Monophasic demyelination reduces brain growth in children

Neurology

Volumn 88, Issue 18, 2017, Pages 1744-1750

  Aubert Broche, Bérengère ^a   Weier, Katrin ^a   Longoni, Giulia ^c   Fonov, Vladimir S ^a   Bar Or, Amit ^b   Marrie, Ruth Ann ^d   Yeh, E Ann ^c   Narayanan, Sridar ^a   Arnold, Douglas L ^a   Verhey, Leonard H ^c   Banwell, Brenda ^e   Collins, D Louis ^a  

^a MCGILL UNIVERSITY   (Canada)

^b MCGILL UNIVERSITY   (Canada)

^c HOSPITAL FOR SICK CHILDREN   (Canada)

^d UNIVERSITY OF MANITOBA   (Canada)

^e UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CORTICOSTEROID;

ACUTE DISSEMINATED ENCEPHALOMYELITIS; ADOLESCENT; ARTICLE; BRAIN CORTEX; BRAIN DAMAGE; BRAIN EDEMA; BRAIN GROWTH; BRAIN SIZE; CATCH UP GROWTH; CENTRAL NERVOUS SYSTEM DISEASE; CHILD; CHILD DEVELOPMENT; CHILDHOOD DISEASE; CORTICOSTEROID THERAPY; DEMYELINATION; FEMALE; GRAY MATTER; GROUPS BY AGE; HUMAN; MAJOR CLINICAL STUDY; MALE; MONOPHASIC ACQUIRED DEMYELINATING SYNDROME; ONSET AGE; PRIORITY JOURNAL; SEX DIFFERENCE; WHITE MATTER; BRAIN; DEMYELINATING DISEASE; DIAGNOSTIC IMAGING; FOLLOW UP; GROWTH, DEVELOPMENT AND AGING; LONGITUDINAL STUDY; NUCLEAR MAGNETIC RESONANCE IMAGING; ORGAN SIZE; PRESCHOOL CHILD; PROSPECTIVE STUDY; YOUNG ADULT;

ADOLESCENT; BRAIN; CHILD; CHILD, PRESCHOOL; DEMYELINATING AUTOIMMUNE DISEASES, CNS; FEMALE; FOLLOW-UP STUDIES; GRAY MATTER; HUMANS; LONGITUDINAL STUDIES; MAGNETIC RESONANCE IMAGING; MALE; ORGAN SIZE; PROSPECTIVE STUDIES; YOUNG ADULT;

EID: 85019541463     PISSN: 00283878     EISSN: 1526632X     Source Type: Journal    
DOI: 10.1212/WNL.0000000000003884     Document Type: Article

References (14)

1. Kerbrat A, Aubert-Broche B, Fonov V, et al. Reduced head and brain size for age and disproportionately smaller thalami in child-onset MS. Neurology 2012;78:194-201.
2. Aubert-Broche B, Fonov V, Ghassemi R, et al. Regional brain atrophy in children with multiple sclerosis. Neuroimage 2011;58:409-415.
3. Aubert-Broche B, Fonov V, Narayanan S, et al. Onset of multiple sclerosis before adulthood leads to failure of ageexpected brain growth. Neurology 2014;83:2140-2146.
4. Harder LL, Holland AA, Frohman E, Graves D, Greenberg BM. Cognitive functioning in pediatric transverse myelitis. Mult Scler 2013;19:947-952.
5. Aubert-Broche B, Fonov V, Weier K, et al. Is it possible to differentiate the impact of pediatric monophasic demyelinating disorders and multiple sclerosis after a first episode of demyelination? In: Durrleman S, Fletcher T, Gerig G, Niethammer M, Pennec X, eds. Spatio-Temporal Image Anal Longitudinal Time-Series Image Data. Cham, Switzerland: Springer International Publishing; 2014:38-48.
6. Banwell B, Bar-Or A, Arnold DL, et al. Clinical, environmental, and genetic determinants of multiple sclerosis in children with acute demyelination: a prospective national cohort study. Lancet Neurol 2011;10:436-445.
7. Polman CH, Reingold SC, Banwell B, et al. Diagnostic criteria for multiple sclerosis: 2010 revisions to the McDonald criteria. Ann Neurol 2011;69:292-302.
8. Wingerchuk DM, Banwell B, Bennett JL, et al. International consensus diagnostic criteria for neuromyelitis optica spectrum disorders. Neurology 2015;85:177-189.
9. Krupp LB, Banwell B, Tenembaum S; International Pediatric MS Study Group. Consensus definitions proposed for pediatric multiple sclerosis and related disorders. Neurology 2007;68:S7-S12.
10. Evans AC; Brain Development Cooperative Group. The NIH MRI study of normal brain development. Neuroimage 2006;30:184-202.
11. Siegel S, Castellan NJ. Nonparametric Statistics for the Behavioral Sciences. 2nd ed. New York:McGraw-Hill; 1988.
12. Smith SM, Zhang Y, Jenkinson M, et al. Accurate, robust, and automated longitudinal and cross-sectional brain change analysis. Neuroimage 2002;17:479-489.
13. Aubert-Broche B, Fonov VS, Garcia-Lorenzo D, et al. A new method for structural volume analysis of longitudinal brain MRI data and its application in studying the growth trajectories of anatomical brain structures in childhood. Neuroimage 2013;82:393-402.
14. Fox RJ, Fisher E, Tkach J, Lee JC, Cohen JA, Rudick RA. Brain atrophy and magnetization transfer ratio following methylprednisolone in multiple sclerosis: short-term changes and long-term implications. Mult Scler 2005;11: 140-145.