Notch-1 knockdown suppresses proliferation, migration and metastasis of salivary adenoid cystic carcinoma cells

Journal of Translational Medicine

Volumn 13, Issue 1, 2015, Pages

  Chen, Wei ^a   Cao, Gang ^a   Yuan, Xinran ^a   Zhang, Xiang ^a   Zhang, Qingqing ^a   Zhu, Yinglan ^a   Dong, Zhen ^a   Zhang, Senlin ^a  

^a NANJING UNIVERSITY   (China)

Author keywords

Adenoid cystic carcinoma; Metastasis; Notch 1; Perineural invasion; RNA interference

Indexed keywords

LENTIVIRUS VECTOR; NOTCH1 RECEPTOR; NOTCH RECEPTOR; SMALL INTERFERING RNA;

ADENOID CYSTIC CARCINOMA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CANCER INHIBITION; CELL MIGRATION; CELL MIGRATION ASSAY; CELL PROLIFERATION; CLONOGENIC ASSAY; CONTROLLED STUDY; DOWN REGULATION; FLOW CYTOMETRY; GENE SILENCING; IN VITRO STUDY; IN VIVO STUDY; LUNG METASTASIS; LUNG NODULE; METASTASIS INHIBITION; MIGRATION INHIBITION; MOUSE; MTT ASSAY; NONHUMAN; NOTCH 1 GENE; PROTEIN FUNCTION; RNA INTERFERENCE; SALIVARY ADENOID CYSTIC CARCINOMA; SALIVARY GLAND CARCINOMA; TRANSWELL ASSAY; TUMOR INVASION; TUMOR XENOGRAFT; ANIMAL; CELL CLONE; CELL CYCLE; CELL MOTION; GENE VECTOR; GENETIC TRANSFECTION; GENETICS; HUMAN; LENTIVIRINAE; METABOLISM; METASTASIS; NUDE MOUSE; PATHOLOGY; REPRODUCIBILITY; SALIVARY GLAND TUMOR; TUMOR CELL LINE;

ANIMALS; APOPTOSIS; CARCINOMA, ADENOID CYSTIC; CELL CYCLE; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; CLONE CELLS; DOWN-REGULATION; GENE KNOCKDOWN TECHNIQUES; GENETIC VECTORS; HUMANS; LENTIVIRUS; MICE, NUDE; NEOPLASM METASTASIS; RECEPTORS, NOTCH; REPRODUCIBILITY OF RESULTS; RNA, SMALL INTERFERING; SALIVARY GLAND NEOPLASMS; TRANSFECTION;

EID: 85019265475     PISSN: None     EISSN: 14795876     Source Type: Journal    
DOI: 10.1186/s12967-015-0520-2     Document Type: Article

References (18)

1. Renehan A, Gleave EN, Hancock BD, Smith P, McGurk M. Long-term follow-up of over 1000 patients with salivary gland tumours treated in a single centre. Br J Surg. 1996;83:1750-4.
2. Fordice J, Kershaw C, El-Naggar A, Goepfert H. Adenoid cystic carcinoma of the head and neck: predictors of morbidity and mortality. Arch Otolaryngol Head Neck Surg. 1999;125:149-52.
3. Van der Wal JE, Becking AG, Snow GB, van der Waal I. Distant metastases of adenoid cystic carcinoma of the salivary glands and the value of diagnostic examinations during follow-up. Head Neck. 2002;24:779-83.
4. Ramer N, Wu H, Sabo E, Ramer Y, Emanuel P, Orta L. Prognostic value of quantitative p63 immunostaining in adenoid cystic carcinoma of salivary gland assessed by computerized image analysis. Cancer. 2010;116:77-83.
5. Go MJ, Eastman DS, Artavanis-Tsakonas S. Cell proliferation control by Notch signaling in Drosophila development. Development. 1998;125:2031-40.
6. Shelly LL, Fuchs C, Miele L. Notch-1 inhibits apoptosis in murine erythroleukemia cells and is necessary for differentiation induced by hybrid polar compounds. J Cell Biochem. 1999;73:164-75.
7. Karamboulas C, Ailles L. Developmental signaling pathways in cancer stem cells of solid tumors. Biochim Biophys Acta. 1830;2013:2481-95.
8. Stephens PJ, Davies HR, Mitani Y, Van Loo P, Shlien A, Tarpey PS. Whole exome sequencing of adenoid cystic carcinoma. J Clin Invest. 2013;123(7):2965-8.
9. Bell D, Hanna EY, Miele L, Roberts D, Weber RS, El-Naggar AK. Expression and significance of notch signaling pathway in salivary adenoid cystic carcinoma. Ann Diagn Pathol. 2014;18:10-3.
10. Lin JT, Chen MK, Yeh KT, Chang CS, Chang TH, Lin CY, et al. Association of high levels of Jagged-1 and Notch-1 expression with poor prognosis in head and neck cancer. Ann Surg Oncol. 2010;17:2976-83.
11. Chen W, Zhang HL, Shao XJ, Jiang YG, Zhao XG, Gao X, et al. Gene expression profile of salivary adenoid cystic carcinoma associated with perineural invasion. Tohoku J Exp Med. 2007;212:319-34.
12. Yao J, Duan L, Fan M, Yuan J, Wu X. Notch1 induces cell cycle arrest and apoptosis in human cervical cancer cells: involvement of nuclear factor kappa B inhibition. Int J Gynecol Cancer. 2007;17:502-10.
13. Duan L, Yao J, Wu X, Fan M. Growth suppression induced by Notch-1 activation involves Wnt-beta-catenin down-regulation in human tongue carcinoma cells. Biol Cell. 2006;98:479-90.
14. Wang T, Xuan X, Pian L, Gao P, Hu H, Zheng Y, et al. Notch-1-mediated esophageal carcinoma EC-9706 cell invasion and metastasis by inducing epithelial-mesenchymal transition through Snail. Tumour Biol. 2014;35(2):1193-201.
15. Xie M, Zhang L, He CS, Xu F, Liu JL, Hu ZH, et al. Activation of Notch-1 enhances epithelial-mesenchymal transition in gefitinib-acquired resistant lung cancer cells. J Cell Biochem. 2012;113(5):1501-13.
16. Ye QF, Zhang YC, Peng XQ, Long Z, Ming YZ, He LY. siRNA-mediated silencing of Notch-1 enhances docetaxel induced mitotic arrest and apoptosis in prostate cancer cells. Asian Pac J Cancer Prev. 2012;13(6):2485-9.
17. Li L, Zhao F, Lu J, Li T, Yang H, Wu C, et al. Notch-1 signaling promotes the malignant features of human breast cancer through NF-κB activation. PLoS One. 2014;9(4), e95912.
18. Chen W, Zhang HL, Wang JD, Cao G, Dong Z, Su H, et al. Lentiviral-mediated gene silencing of Notch-4 inhibits in vitro proliferation and perineural invasion of ACC-M cells. Oncol Rep. 2013;29:1797-804.