Rocuronium vs. succinylcholine for rapid sequence intubation: a Cochrane systematic review

Anaesthesia

Volumn 72, Issue 6, 2017, Pages 765-777

  Tran, D T T ^a   Newton, E K ^a   Mount, V A H ^b   Lee, J S ^c   Mansour, C ^a   Wells, G A ^a   Perry, J J ^a,d  

^a UNIVERSITY OF OTTAWA HEART INSTITUTE   (Canada)

^b QUEEN S UNIVERSITY   (Canada)

^c SUNNYBROOK RESEARCH INSTITUTE   (Canada)

^d UNIVERSITY OF OTTAWA   (Canada)

Author keywords

laryngoscopic view; muscle relaxation

Indexed keywords

ROCURONIUM; SUXAMETHONIUM; THIOPENTAL; NEUROMUSCULAR BLOCKING AGENT; NEUROMUSCULAR DEPOLARIZING AGENT;

ANESTHESIA INDUCTION; COCHRANE LIBRARY; COMPARATIVE EFFECTIVENESS; CONTROLLED CLINICAL TRIAL (TOPIC); DRUG EFFICACY; EMBASE; ENDOTRACHEAL INTUBATION; EVIDENCE BASED PRACTICE; HUMAN; INCIDENCE; MEDLINE; META ANALYSIS; META ANALYSIS (TOPIC); RANDOMIZED CONTROLLED TRIAL (TOPIC); REVIEW; SYSTEMATIC REVIEW; COMPARATIVE STUDY; PROCEDURES;

HUMANS; INTUBATION, INTRATRACHEAL; NEUROMUSCULAR DEPOLARIZING AGENTS; NEUROMUSCULAR NONDEPOLARIZING AGENTS; RANDOMIZED CONTROLLED TRIALS AS TOPIC; ROCURONIUM; SUCCINYLCHOLINE;

EID: 85019049727     PISSN: 00032409     EISSN: 13652044     Source Type: Journal    
DOI: 10.1111/anae.13903     Document Type: Review

References (70)

1. Huizinga AC, Vandenbrom RH, Wierda JM, Hommes FD, Hennis PJ. Intubating conditions and onset of neuromuscular block of rocuronium (Org 9426); a comparison with suxamethonium. Acta Anaesthesiologica Scandinavica 1992; 36: 463–8.
2. McCourt KC, Salmela L, Mirakhur RK, et al. Comparison of rocuronium and suxamethonium for use during rapid sequence induction of anaesthesia. Anaesthesia 1998; 53: 867–71.
3. Stollings JL, Diedrich DA, Oyen LJ, Brown DR. Rapid sequence intubation: a review of the process and considerations when choosing medications. Annals of Pharmacotherapy 2014; 48: 62–76.
4. Frerk C, Mitchell VS, McNarry AF, et al. Difficult Airway Society 2015 guidelines for management of unanticipated difficult intubation in adults. British Journal of Anaesthesia 2015; 115: 827–48.
5. Rosenblatt WH. Airway Management. In: Barash PG, Cullen BF, Stoelting RK, eds. Clinical Anesthesia, 4th edn. Philadelphia: Lippincott Williams & Wilkins, 2001: 610.
6. Weiss JH, Gratz I, Goldberg ME, Afshar M, Insinga F, Larijani G. Double-blind comparison of two doses of rocuronium and succinylcholine for rapid-sequence intubation. Journal of Clinical Anesthesia 1997; 9: 379–82.
7. Minton MD, Grosslight K, Stirt JA, Bedford RF. Increases in intracranial pressure from succinylcholine: prevention by prior nondepolarizing blockade. Anesthesiology 1986; 65: 165–9.
8. Vinik HR. Intraocular pressure changes during rapid sequence induction and intubation: a comparison of rocuronium, atracurium, and succinylcholine. Journal of Clinical Anesthesia 1999; 11: 95–100.
9. Combs JM, Combs GN. A literature review of the newest muscle relaxant: org 9426. The Clinical Forum for Nurse Anesthetists 1994; 5: 104–12.
10. Schreiber JU, Lysakowski C, Fuchs-Buder T, Tramer MR. Prevention of succinylcholine-induced fasciculation and myalgia: a meta-analysis of randomized trials. Anesthesiology 2005; 103: 877–84.
11. Sullivan M, Thompson WK, Hill GD. Succinylcholine-induced cardiac arrest in children with undiagnosed myopathy. Canadian Journal of Anesthesia 1994; 41: 497–501.
12. Martyn JA, Richtsfeld M. Succinylcholine-induced hyperkalemia in acquired pathologic states: etiologic factors and molecular mechanisms. Anesthesiology 2006; 104: 158–69.
13. Lebowitz PW, Ramsey FM. Muscle relaxants. Clinical Anesthesia 1989; 1: 344–6.
14. Magorian T, Flannery KB, Miller RM. Comparison of rocuronium, succinylcholine, and vecuronium for rapid-sequence induction of anesthesia in adult patients. Anesthesiology 1993; 79: 913–8.
15. RC0781-000. Sugammadex for the Reversal of Neuromuscular Blockade in Adult Patients: A Review of Clinical Effectiveness and Cost-Effectiveness. Ottawa: Canadian Agency for Drugs and Technolologies in Health, 2016.
16. Keating GM. Sugammadex: a review of neuromuscular blockade reversal. Drugs 2016; 76: 1041–52.
17. Haynes RB, Wilczynski N, McKibbon KA, Walker CJ, Sinclair JC. Developing optimal search strategies for detecting clinically sound studies in MEDLINE. Journal of the American Medical Informatics Association 1994; 1: 447–58.
18. Tran DTT, Newton EK, Mount VAH, Lee JS, Wells GA, Perry JJ. Rocuronium vs. succinylcholine for rapid sequence induction intubation. Cochrane Database of Systematic Reviews 2015; Art. No. CD002788. DOI: 10.1002/14651858.
19. Danzl DF. Tracheal intubation and mechanical ventillation. In: Tintinalli JE, Kelen GD, Stapczynski JS, eds. Emergency Medicine–A Comprehensive Study Guide. Toronto: McGraw-Hill, 2000: 85–96.
20. Sluga M, Ummenhofer W, Studer W, Siegemund M, Marsch SC. Rocuronium versus succinylcholine for rapid sequence induction of anesthesia and endotracheal intubation: a prospective, randomized trial in emergent cases. Anesthesia and Analgesia 2005; 101: 1356–61.
21. Goldberg ME, Larijani GE, Azad SS, et al. Comparison of tracheal intubating conditions and neuromuscular blocking profiles after intubating doses of mivacurium chloride or succinylcholine in surgical outpatients. Anesthesia and Analgesia 1989; 69: 93–9.
22. Higgins JPT, Thompson SG, Deeks JJ, Altman DG. Measuring inconsistency in meta-analyses. British Medical Journal 2003; 327: 557–60.
23. Abdulatif M, Al-Ghamdi A, El-Sanabary M. Rocuronium priming of atracurium-induced neuromuscular blockade: the use of short priming intervals. Journal of Clinical Anesthesia 1996; 8: 376–81.
24. Abu-Halaweh SA, Massad IM, Abu-Ali HM, Badran IZ, Barazangi BA, Ramsay MA. Rapid sequence induction and intubation with 1 mg/kg rocuronium bromide in cesarean section, comparison with suxamethonium. Saudi Medical Journal 2007; 28: 1393–6.
25. Alanoglu Z, Ates Y, Yilmaz AA, Tuzuner F. Is there an ideal approach for rapid-sequence induction in hypertensive patients? Journal of Clinical Anesthesia 2006; 18: 34–40.
26. Ali J, Gurckoo SA, Shora A, Qazi S. Intubating conditions of rocuronium bromide and succinylcholine during rapid sequence induction of anaesthesia in unpremedicated adult patients. Journal of Anaesthesiology Clinical Pharmacology 2008; 24: 337–42.
27. Alvarez Rios JJ, Hernandez MV, Baez L, Meza G, Higuera E, Gomez B. Analysis of the effects of rocuronium, mivacurium and succinicholine for endotracheal intubaction. Revista Mexicana de Anestesiologia 1997; 20: 122–6.
28. Andrews JI, Kumar N, Van den Brom RH, Olkkola KT, Roest GJ, Wright PM. A large simple randomized trial of rocuronium vs succinylcholine in rapid-sequence induction of anaesthesia along with propofol. Acta Anaesthesiologica Scandinavica 1999; 43: 4–8.
29. Belyamani L, Azendour A, Elhassouni A, Zidouh S, Atmani M, Kamili ND. Effect of ephedrine on the intubation conditions using rocuronium vs. succinylcholine. Annales Français d'Anesthesie et de Reanimation 2008; 27: 292–6.
30. Cheng CA, Aun CA, Gin T. Comparison of rocuronium and suxamethonium for rapid tracheal intubation in children. Paediatric Anesthesia 2002; 12: 140–5.
31. Chiu CL, Jaais J, Wang CY. Effect of rocuronium compared with succinylcholine on intraocular pressure during rapid sequence induction of anaesthesia. British Journal of Anaesthesia 1999; 82: 757–60.
32. Chung YT, Yeh LT. Effectiveness and safety of rocuronium-hypnotic sequence for rapid-sequence induction. Acta Anaesthesiologica Sinica 2001; 39: 3–9.
33. Cooper R, Mirakhur RK, Clarke RS, Boules Z. Comparison of intubating conditions after administration of Org 9246 (rocuronium) and suxamethonium. British Journal of Anaesthesia 1992; 69: 269–73.
34. De Almeida MC, Pederneiras SG, Chiaroni S, De Souze L, Locks GF. Evaluation of tracheal intubation conditions in morbidly obese patients: a comparison of succinylcholine and rocuronium. Revista Española de Anestesiologia y Reanimacion 2009; 56: 3–8.
35. Dubois M, Lea D, Kataria B, Gadde P, Tran D, Shearrow T. Pharmacodynamics of rocuronium with and without prior administration of succinylcholine. Journal of Clinical Anesthesia 1995; 7: 44–8.
36. Giudice G, Tomassini G, Baggianini A, Sagredini R. Speed and ease of endotracheal untubation with the neuromuscular monitoring guide (TOF) after rocuronium doses of various multiples of ED95 and succinylcholine. Acta Anaesthesiologica Italica 1998; 49: 231–9.
37. Iqbal M, Turab SM, Siddiqui MH, et al. To compare the efficacy of rocuronium bromide and succinylcholine in elective surgery for endotracheal tube. Medical Forum Monthly 2013; 24: 38–41.
38. Koroglu N, Iyilikci L, Van Koroglu L, Atay A, Gokel E. Comparison of rocuronium and succinylcholine for rapid sequence intubation cesarian section. Turk Anesteziyoloji ve Reanimasyon Cemiyeti Mecmuasi 2002; 30: 173–80.
39. Kulkarni K, Patil M, Shirke A. Comparison of intubating conditions of succinylcholine with two doses of rocuronium bromide in children. Journal of Anaesthesiology Clinical Pharmacology 2010; 26: 323–28.
40. Kwon MA, Song J, Kim J-R. Tracheal intubation with rocuronium using a “modified timing principle”. Korean Journal of Anesthesiology 2013; 64: 218–22.
41. Lam AM, Pavlin EG, Visco E, Taraday J. Rocuronium vs succinylcholine-atracurium for tracheal intubation and maintenance relaxation during propofol anesthesia. Journal of Clinical Anesthesia 2000; 12: 449–53.
42. Larsen PB, Hansen EG, Jocobsen LS, et al. Intubation conditions after rocuronium or succinylcholine for rapid sequence induction with alfentanil and propofol in the emergency patient. European Journal of Anaesthesiology 2005; 22: 748–53.
43. Latorre F, Stanek A, Gervais HW, Kleeman PP. Intubationsbedingungen nach Rocuronium und Succinylcholin. Anästhesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie 1996; 31: 470–3.
44. Le Corre F, Plaud B, Benhamou E, Debaene B. Visual estimation of onset time at the orbicularis oculi after five muscle relaxants: application to clinical monitoring of tracheal intubation. Anesthesia and Analgesia 1999; 89: 1305–10.
45. Malik P, Rao S, Malhotra N, Chugh JP, Hooda S. Comparative evaluation of effect of rocuronium and succinylcholine on intraocular pressure. Journal of Anaesthesiology Clinical Pharmacology 2004; 20: 255–61.
46. Marsch SC, Steiner L, Bucher E, et al. Succinylcholine vs. rocuronium for rapid sequence intubation in intensive care: a prospective, randomized controlled trial. Critical Care 2011; 15: R199.
47. Mazurek AJ, Rae B, Hann S, Kim I, Castro B, Cote CJ. Rocuronium versus succinylcholine: are they equally effective during rapid-sequence induction of anesthesia? Anesthesia and Analgesia 1998; 87: 1259–62.
48. Mencke T, Scherelber J-U, Knoll H, et al. Influence of gender on the intubation conditions with rocuronium. Der Anaesthesist 2005; 54: 884–88.
49. Mencke T, Knoll H, Shreiber JU, et al. Rocuronium is not associated with more vocal cord injuries than succinylcholine after rapid-sequence induction: a randomized, prospective, controlled trial. Anesthesia and Analgesia 2006; 102: 943–9.
50. Mitra S, Gombar KK, Gombar S. The effect of rocuronium on intraocular pressure: a comparison with succinylcholine. European Journal of Anaesthesiology 2001; 18: 836–8.
51. Naguib M. Different priming techniques, including mivacurium, accelerate the onset of rocuronium. Canadian Journal of Anesthesia 1994; 41: 902–7.
52. Naguib M, Samarkandi AH, Ammar A, Turkistani A. Comparison of suxamethonium and different combinations of rocuronium and mivacurium for rapid tracheal intubation in children. British Journal of Anaesthesia 1997; 79: 450–5.
53. Nelson JM, Morell RC, Butterworth JF. Rocuronium versus succinylcholine for rapid-sequence induction using a variation of the timing principle. Journal of Clinical Anesthesia 1997; 9: 317–20.
54. Patel N, Smith CE, Pinchak AC. Emergency surgery and rapid sequence intubation: rocuronium vs succinylcholine. Anesthesiology 1995; 83: A914.
55. Puhringer FK, Khuenl-Brady KS, Koller J, Mitterschiffthaler G. Evaluation of the endotracheal intubating conditions of rocuronium (ORG 9426) and succinylcholine in outpatient surgery. Anesthesia and Analgesia 1992; 75: 37–40.
56. Ratan Singh N, Thangluai T, Laithangbam PKS, Hemjit Singh T, Chaoba Singh L, Shanti Devi RK. Comparison of intubating conditions of succinylcholine, vecuronium and rocuronium in patients undergoing elective surgery–a study. Journal of Medical Society 2011; 25: 54–8.
57. Sorensen MK, Bretlau C, Gatke MR, Sorensen AM, Rasmussen LS. Rapid sequence induction and intubation with rocuronium-sugammadex compared with succinylcholine: a randomized trial. British Journal of Anaesthesia 2012; 108: 682–9.
58. Sparr HJ, Luger TJ, Heidegger T, Putensen-Himmer G. Comparison of intubating conditions after rocuronium and suxamethonium following “rapid-sequence induction” with thiopentone in elective cases. Acta Anaesthesiologica Scandinavica 1996; 40: 425–30.
59. Sparr HJ, Giesinger S, Ulmer H, Hollenstein-Zache M, Luger TJ. Influence of induction technique on intubating conditions after rocuronium in adults: comparison with rapid-sequence induction using thiopentone and suxamethonium. British Journal of Anaesthesia 1996; 77: 339–42.
60. Stevens JB, Shepherd JM, Vories PA, Walker SC, Vescovo MV. A mixture of mivacurium and rocuronium is comparable in clinical onset to succinylcholine. Journal of Clinical Anesthesia 1996; 8: 486–90.
61. Stoddart PA, Mather SJ. Onset of neuromuscular blockade and intubating conditions one minute after the administration of rocuronium in children. Paediatric Anesthesia 1998; 8: 37–40.
62. Tang J, Joshi GP, White PF. Comparison of rocuronium and mivacurium to succinylcholine during outpatient laparoscopic surgery. Anesthesia and Analgesia 1996; 82: 994–8.
63. Tripathi D, Trivedi L, Doshi S, Shah C, Sheth P. Evaluation of onset of action and endotracheal intubating conditions after suxamethonium chloride and rocuronium bromide in adults. Journal of Anaesthesiology Clinical Pharmacology 2010; 26: 350–4.
64. Tryba M, Zorn A, Thole H, Zenz M. Rapid-sequence orotracheal intubation with rocuronium: a randomized double-blind comparison with suxamethonium–Preliminary communication. European Journal of Anaesthesiology 1994; 11: 44–8.
65. Turan G, Ozgultekin A, Bafali M, Kasikci M, Senel NA. Is rocuronium an alternative to succinylcholine? Türk Anesteziyoloji ve Reanimasyon Derne 1999; 27: 193–7.
66. Türkmen A, Altan A, Turgut N, et al. Mivacurium in balanced anesthesia, intubation with succinylcholine rocuronium and conditions and clinical effects comparison of time. Türk Anesteziyoloji ve Reanimasyon Dernegi Dergisi 2004; 322: 85–90.
67. Yorukoglu D, Asik Y, Okten F. Rocuronium combined with i.v. lidocaine for rapid tracheal intubation. Acta Anaesthesiologica Scandinavica 2003; 47: 583–7.
68. Soto R, Jahr JS, Pavlin J, et al. Safety and efficacy of rocuronium with sugammadex reversal vs. succinylcholine in outpatient surgery–a multicenter, randomized, safety assessor-blinded trial. American Journal of Therapeutics 2015; 23: 1654–62.
69. Patanwala AE, Stahle SA, Erstad BL. Comparison of succinylcholine and rocuronium for first-attempt intubation success in the emergency department. Academic Emergency Medicine 2011; 18: 10–4.
70. Herbstritt A, Amarakone K. Towards evidence-based emergency medicine: best BETs from the Manchester Royal Infirmary. BET 3: is rocuronium as effective as succinylcholine at facilitating laryngoscopy during rapid sequence intubation? Emergency Medicine Journal 2012; 29: 256–8.