Septal Cholinergic Neuromodulation Tunes the Astrocyte-Dependent Gating of Hippocampal NMDA Receptors to Wakefulness

Neuron

Volumn 94, Issue 4, 2017, Pages 840-854.e7

  Papouin, Thomas ^a   Dunphy, Jaclyn M ^b   Tolman, Michaela ^b   Dineley, Kelly T ^c   Haydon, Philip G ^a  

^a TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b TUFTS UNIVERSITY   (United States)

^c University of Texas Medical Branch School of Medicine   (United States)

Author keywords

acetylcholine; astrocytes; contextual guidance; D serine; EVP 6124; NMDAR; schizophrenia; vigilance state; wakefulness; 7nAChR

Indexed keywords

ENCENICLINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; 7-CHLORO-N-QUINUCLIDIN-3-YL-BENZO(B)THIOPHENE-2-CARBOXAMIDE; BUNGAROTOXIN RECEPTOR; CHRNA7 PROTEIN, MOUSE; NICOTINIC AGENT; QUINUCLIDINE DERIVATIVE; SERINE; THIOPHENE DERIVATIVE;

ADULT; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BINDING SITE; CHOLINERGIC ACTIVITY; CHOLINERGIC SYSTEM; CONCEPTUAL FRAMEWORK; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME DEGRADATION; ENZYME SYNTHESIS; EXCITATORY POSTSYNAPTIC POTENTIAL; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HIPPOCAMPAL SLICE; HIPPOCAMPUS; LEARNING; MALE; MOUSE; NEUROMODULATION; NEUROTRANSMISSION; NONHUMAN; OPTOGENETICS; PRIORITY JOURNAL; SENSORY GATING; SIGNAL TRANSDUCTION; STRATUM RADIATUM; SYNAPSE; SYNAPTIC TRANSMISSION; TISSUE OXYGENATION; WAKEFULNESS; AGONISTS; ANIMAL; ANIMAL BEHAVIOR; CONDITIONING; CYTOLOGY; DRUG EFFECTS; ELECTROENCEPHALOGRAPHY; ELECTROMYOGRAPHY; FEAR; FLUORESCENCE IMAGING; GENETICS; IMMUNOHISTOCHEMISTRY; MEMORY; METABOLISM; MICRODIALYSIS; NECK MUSCLE; SCHIZOPHRENIA; TRANSGENIC MOUSE;

ALPHA7 NICOTINIC ACETYLCHOLINE RECEPTOR; ANIMALS; ASTROCYTES; BEHAVIOR, ANIMAL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CONDITIONING (PSYCHOLOGY); ELECTROENCEPHALOGRAPHY; ELECTROMYOGRAPHY; EXCITATORY POSTSYNAPTIC POTENTIALS; FEAR; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; LEARNING; MEMORY; MICE; MICE, TRANSGENIC; MICRODIALYSIS; NECK MUSCLES; NICOTINIC AGONISTS; OPTICAL IMAGING; OPTOGENETICS; QUINUCLIDINES; RECEPTORS, N-METHYL-D-ASPARTATE; SCHIZOPHRENIA; SERINE; SYNAPSES; THIOPHENES; WAKEFULNESS;

EID: 85018998406     PISSN: 08966273     EISSN: 10974199     Source Type: Journal    
DOI: 10.1016/j.neuron.2017.04.021     Document Type: Article

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