-
1
-
-
33646794392
-
Checkpoint blockade in cancer immunotherapy
-
Korman, A. J., Peggs, K. S. & Allison, J. P. Checkpoint blockade in cancer immunotherapy. Adv. Immunol. 90, 297-339 (2006).
-
(2006)
Adv. Immunol.
, vol.90
, pp. 297-339
-
-
Korman, A.J.1
Peggs, K.S.2
Allison, J.P.3
-
2
-
-
84927130807
-
Immune checkpoint targeting in cancer therapy: Toward combination strategies with curative potential
-
Sharma, P. & Allison, J. P. Immune checkpoint targeting in cancer therapy: toward combination strategies with curative potential. Cell 161, 205-214 (2015).
-
(2015)
Cell
, vol.161
, pp. 205-214
-
-
Sharma, P.1
Allison, J.P.2
-
3
-
-
84939625807
-
Phagocytosis of apoptotic cells in homeostasis
-
Arandjelovic, S. & Ravichandran, K. S. Phagocytosis of apoptotic cells in homeostasis. Nat. Immunol. 16, 907-917 (2015).
-
(2015)
Nat. Immunol.
, vol.16
, pp. 907-917
-
-
Arandjelovic, S.1
Ravichandran, K.S.2
-
4
-
-
84911092143
-
Macrophage heterogeneity in tissues: Phenotypic diversity and functions
-
Gordon, S., Plüddemann, A. & Martinez Estrada, F. Macrophage heterogeneity in tissues: phenotypic diversity and functions. Immunol. Rev. 262, 36-55 (2014).
-
(2014)
Immunol. Rev.
, vol.262
, pp. 36-55
-
-
Gordon, S.1
Plüddemann, A.2
Martinez Estrada, F.3
-
5
-
-
84961918625
-
Molecular features of macrophage activation
-
Schultze, J. L. & Schmidt, S. V. Molecular features of macrophage activation. Semin. Immunol. 27, 416-423 (2015).
-
(2015)
Semin. Immunol.
, vol.27
, pp. 416-423
-
-
Schultze, J.L.1
Schmidt, S.V.2
-
6
-
-
84911122639
-
Phagocytosis: Receptors, signal integration, and the cytoskeleton
-
Freeman, S. A. & Grinstein, S. Phagocytosis: receptors, signal integration, and the cytoskeleton. Immunol. Rev. 262, 193-215 (2014).
-
(2014)
Immunol. Rev.
, vol.262
, pp. 193-215
-
-
Freeman, S.A.1
Grinstein, S.2
-
7
-
-
77956150056
-
Anti-CD47 antibody synergizes with rituximab to promote phagocytosis and eradicate non-Hodgkin lymphoma
-
Chao, M. P. et al. Anti-CD47 antibody synergizes with rituximab to promote phagocytosis and eradicate non-Hodgkin lymphoma. Cell 142, 699-713 (2010).
-
(2010)
Cell
, vol.142
, pp. 699-713
-
-
Chao, M.P.1
-
8
-
-
67650632683
-
CD47 is an adverse prognostic factor and therapeutic antibody target on human acute myeloid leukemia stem cells
-
Majeti, R. et al. CD47 is an adverse prognostic factor and therapeutic antibody target on human acute myeloid leukemia stem cells. Cell 138, 286-299 (2009).
-
(2009)
Cell
, vol.138
, pp. 286-299
-
-
Majeti, R.1
-
9
-
-
67650646082
-
CD47 is upregulated on circulating hematopoietic stem cells and leukemia cells to avoid phagocytosis
-
Jaiswal, S. et al. CD47 is upregulated on circulating hematopoietic stem cells and leukemia cells to avoid phagocytosis. Cell 138, 271-285 (2009).
-
(2009)
Cell
, vol.138
, pp. 271-285
-
-
Jaiswal, S.1
-
10
-
-
84869200371
-
Disruption of SIRP? Signaling in macrophages eliminates human acute myeloid leukemia stem cells in xenografts
-
Theocharides, A. P. et al. Disruption of SIRP? signaling in macrophages eliminates human acute myeloid leukemia stem cells in xenografts. J. Exp. Med. 209, 1883-1899 (2012).
-
(2012)
J. Exp. Med.
, vol.209
, pp. 1883-1899
-
-
Theocharides, A.P.1
-
11
-
-
84901844609
-
The CD47-SIRP? Signalling system: Its physiological roles and therapeutic application
-
Murata, Y., Kotani, T., Ohnishi, H. & Matozaki, T. The CD47-SIRP? signalling system: its physiological roles and therapeutic application. J. Biochem. 155, 335-344 (2014).
-
(2014)
J. Biochem.
, vol.155
, pp. 335-344
-
-
Murata, Y.1
Kotani, T.2
Ohnishi, H.3
Matozaki, T.4
-
12
-
-
84893587799
-
The interaction between signal regulatory protein alpha (SIRP? ) and CD47: Structure, function, and therapeutic target
-
Barclay, A. N. & Van den Berg, T. K. The interaction between signal regulatory protein alpha (SIRP? ) and CD47: structure, function, and therapeutic target. Annu. Rev. Immunol. 32, 25-50 (2014).
-
(2014)
Annu. Rev. Immunol.
, vol.32
, pp. 25-50
-
-
Barclay, A.N.1
Van Den Berg, T.K.2
-
13
-
-
84859158880
-
The CD47-SIRP? Pathway in cancer immune evasion and potential therapeutic implications
-
Chao, M. P., Weissman, I. L. & Majeti, R. The CD47-SIRP? pathway in cancer immune evasion and potential therapeutic implications. Curr. Opin. Immunol. 24, 225-232 (2012).
-
(2012)
Curr. Opin. Immunol.
, vol.24
, pp. 225-232
-
-
Chao, M.P.1
Weissman, I.L.2
Majeti, R.3
-
14
-
-
84886945224
-
Targeting SIRP? In cancer
-
Ho, J. M., Danska, J. S. & Wang, J. C. Targeting SIRP? in cancer. OncoImmunology 2, e23081 (2013).
-
(2013)
OncoImmunology
, vol.2
, pp. e23081
-
-
Ho, J.M.1
Danska, J.S.2
Wang, J.C.3
-
15
-
-
84949293993
-
SLAM family receptors in normal immunity and immune pathologies
-
Wu, N. & Veillette, A. SLAM family receptors in normal immunity and immune pathologies. Curr. Opin. Immunol. 38, 45-51 (2016).
-
(2016)
Curr. Opin. Immunol.
, vol.38
, pp. 45-51
-
-
Wu, N.1
Veillette, A.2
-
16
-
-
79953060006
-
SLAM family receptors and SAP adaptors in immunity
-
Cannons, J. L., Tangye, S. G. & Schwartzberg, P. L. SLAM family receptors and SAP adaptors in immunity. Annu. Rev. Immunol. 29, 665-705 (2011).
-
(2011)
Annu. Rev. Immunol.
, vol.29
, pp. 665-705
-
-
Cannons, J.L.1
Tangye, S.G.2
Schwartzberg, P.L.3
-
17
-
-
43849103008
-
The SLAM and SAP gene families control innate and adaptive immune responses
-
Calpe, S. et al. The SLAM and SAP gene families control innate and adaptive immune responses. Adv. Immunol. 97, 177-250 (2008).
-
(2008)
Adv. Immunol.
, vol.97
, pp. 177-250
-
-
Calpe, S.1
-
18
-
-
9644289575
-
Integrins: Versatile integrators of extracellular signals
-
ffrench-Constant, C. & Colognato, H. Integrins: versatile integrators of extracellular signals. Trends Cell Biol. 14, 678-686 (2004).
-
(2004)
Trends Cell Biol.
, vol.14
, pp. 678-686
-
-
Ffrench-Constant, C.1
Colognato, H.2
-
19
-
-
0036222549
-
Sensing the environment: A historical perspective on integrin signal transduction
-
Miranti, C. K. & Brugge, J. S. Sensing the environment: a historical perspective on integrin signal transduction. Nat. Cell Biol. 4, E83-E90 (2002).
-
(2002)
Nat. Cell Biol.
, vol.4
, pp. E83-E90
-
-
Miranti, C.K.1
Brugge, J.S.2
-
20
-
-
28444497446
-
Integrin structure, allostery, and bidirectional signaling
-
Arnaout, M. A., Mahalingam, B. & Xiong, J. P. Integrin structure, allostery, and bidirectional signaling. Annu. Rev. Cell Dev. Biol. 21, 381-410 (2005).
-
(2005)
Annu. Rev. Cell Dev. Biol.
, vol.21
, pp. 381-410
-
-
Arnaout, M.A.1
Mahalingam, B.2
Xiong, J.P.3
-
21
-
-
35248851278
-
Immunoreceptor-like signaling by ? 2 and ? 3 integrins
-
Jakus, Z., Fodor, S., Abram, C. L., Lowell, C. A. & Mócsai, A. Immunoreceptor-like signaling by ? 2 and ? 3 integrins. Trends Cell Biol. 17, 493-501 (2007).
-
(2007)
Trends Cell Biol.
, vol.17
, pp. 493-501
-
-
Jakus, Z.1
Fodor, S.2
Abram, C.L.3
Lowell, C.A.4
Mócsai, A.5
-
22
-
-
70350414455
-
The expanding roles of ITAM adapters FcR? And DAP12 in myeloid cells
-
Hamerman, J. A., Ni, M., Killebrew, J. R., Chu, C. L. & Lowell, C. A. The expanding roles of ITAM adapters FcR? and DAP12 in myeloid cells. Immunol. Rev. 232, 42-58 (2009).
-
(2009)
Immunol. Rev.
, vol.232
, pp. 42-58
-
-
Hamerman, J.A.1
Ni, M.2
Killebrew, J.R.3
Chu, C.L.4
Lowell, C.A.5
-
23
-
-
78650664067
-
Calreticulin is the dominant pro-phagocytic signal on multiple human cancers and is counterbalanced by CD47
-
Chao, M. P. et al. Calreticulin is the dominant pro-phagocytic signal on multiple human cancers and is counterbalanced by CD47. Sci. Transl. Med. 2, 63ra94 (2010).
-
(2010)
Sci. Transl. Med.
, vol.2
, pp. 63ra94
-
-
Chao, M.P.1
-
24
-
-
84884164729
-
CS1, a SLAM family receptor involved in immune regulation, is a therapeutic target in multiple myeloma
-
Veillette, A. & Guo, H. CS1, a SLAM family receptor involved in immune regulation, is a therapeutic target in multiple myeloma. Crit. Rev. Oncol. Hematol. 88, 168-177 (2013).
-
(2013)
Crit. Rev. Oncol. Hematol.
, vol.88
, pp. 168-177
-
-
Veillette, A.1
Guo, H.2
-
25
-
-
84920019769
-
Immune cell inhibition by SLAMF7 is mediated by a mechanism requiring Src kinases, CD45, and SHIP-1 that is defective in multiple myeloma cells
-
Guo, H., Cruz-Munoz, M. E., Wu, N., Robbins, M. & Veillette, A. Immune cell inhibition by SLAMF7 is mediated by a mechanism requiring Src kinases, CD45, and SHIP-1 that is defective in multiple myeloma cells. Mol. Cell. Biol. 35, 41-51 (2015).
-
(2015)
Mol. Cell. Biol.
, vol.35
, pp. 41-51
-
-
Guo, H.1
Cruz-Munoz, M.E.2
Wu, N.3
Robbins, M.4
Veillette, A.5
-
26
-
-
0027305921
-
Mutation of unique region of Bruton's tyrosine kinase in immunodeficient XID mice
-
Rawlings, D. J. et al. Mutation of unique region of Bruton's tyrosine kinase in immunodeficient XID mice. Science 261, 358-361 (1993).
-
(1993)
Science
, vol.261
, pp. 358-361
-
-
Rawlings, D.J.1
-
27
-
-
0028042424
-
FcR ? Chain deletion results in pleiotrophic effector cell defects
-
Takai, T., Li, M., Sylvestre, D., Clynes, R. & Ravetch, J. V. FcR ? chain deletion results in pleiotrophic effector cell defects. Cell 76, 519-529 (1994).
-
(1994)
Cell
, vol.76
, pp. 519-529
-
-
Takai, T.1
Li, M.2
Sylvestre, D.3
Clynes, R.4
Ravetch, J.V.5
-
28
-
-
0030188493
-
The continuing saga of complement receptor type 3 (CR3)
-
Todd, R. F. III. The continuing saga of complement receptor type 3 (CR3). J. Clin. Invest. 98, 1-2 (1996).
-
(1996)
J. Clin. Invest.
, vol.98
, pp. 1-2
-
-
Todd, R.F.1
-
29
-
-
84992183727
-
Deletion of Slam locus in mice reveals inhibitory role of SLAM family in NK cell responses regulated by cytokines and LFA-1
-
Guo, H. et al. Deletion of Slam locus in mice reveals inhibitory role of SLAM family in NK cell responses regulated by cytokines and LFA-1. J. Exp. Med. 213, 2187-2207 (2016).
-
(2016)
J. Exp. Med.
, vol.213
, pp. 2187-2207
-
-
Guo, H.1
-
30
-
-
84958069162
-
A hematopoietic cell-driven mechanism involving SLAMF6 receptor, SAP adaptors and SHP-1 phosphatase regulates NK cell education
-
Wu, N. et al. A hematopoietic cell-driven mechanism involving SLAMF6 receptor, SAP adaptors and SHP-1 phosphatase regulates NK cell education. Nat. Immunol. 17, 387-396 (2016).
-
(2016)
Nat. Immunol.
, vol.17
, pp. 387-396
-
-
Wu, N.1
-
31
-
-
84862976954
-
The adaptor SAP controls NK cell activation by regulating the enzymes Vav-1 and SHIP-1 and by enhancing conjugates with target cells
-
Dong, Z. et al. The adaptor SAP controls NK cell activation by regulating the enzymes Vav-1 and SHIP-1 and by enhancing conjugates with target cells. Immunity 36, 974-985 (2012).
-
(2012)
Immunity
, vol.36
, pp. 974-985
-
-
Dong, Z.1
-
32
-
-
80054728763
-
Deletion of Syk in neutrophils prevents immune complex arthritis
-
Elliott, E. R. et al. Deletion of Syk in neutrophils prevents immune complex arthritis. J. Immunol. 187, 4319-4330 (2011).
-
(2011)
J. Immunol.
, vol.187
, pp. 4319-4330
-
-
Elliott, E.R.1
-
33
-
-
0037314230
-
Osteopetrosis and thalamic hypomyelinosis with synaptic degeneration in DAP12-deficient mice
-
Kaifu, T. et al. Osteopetrosis and thalamic hypomyelinosis with synaptic degeneration in DAP12-deficient mice. J. Clin. Invest. 111, 323-332 (2003).
-
(2003)
J. Clin. Invest.
, vol.111
, pp. 323-332
-
-
Kaifu, T.1
-
34
-
-
33846295127
-
Integrin signaling in neutrophils and macrophages uses adaptors containing immunoreceptor tyrosine-based activation motifs
-
Mócsai, A. et al. Integrin signaling in neutrophils and macrophages uses adaptors containing immunoreceptor tyrosine-based activation motifs. Nat. Immunol. 7, 1326-1333 (2006).
-
(2006)
Nat. Immunol.
, vol.7
, pp. 1326-1333
-
-
Mócsai, A.1
-
35
-
-
84878971365
-
Macrophage fusion is controlled by the cytoplasmic protein tyrosine phosphatase PTP-PEST/ PTPN12
-
Rhee, I., Davidson, D., Souza, C. M., Vacher, J. & Veillette, A. Macrophage fusion is controlled by the cytoplasmic protein tyrosine phosphatase PTP-PEST/ PTPN12. Mol. Cell. Biol. 33, 2458-2469 (2013).
-
(2013)
Mol. Cell. Biol.
, vol.33
, pp. 2458-2469
-
-
Rhee, I.1
Davidson, D.2
Souza, C.M.3
Vacher, J.4
Veillette, A.5
-
36
-
-
69049110783
-
Essential function for SAP family adaptors in the surveillance of hematopoietic cells by natural killer cells
-
Dong, Z. et al. Essential function for SAP family adaptors in the surveillance of hematopoietic cells by natural killer cells. Nat. Immunol. 10, 973-980 (2009).
-
(2009)
Nat. Immunol.
, vol.10
, pp. 973-980
-
-
Dong, Z.1
-
37
-
-
0028046647
-
Two distinct protein isoforms are encoded by ntk, a csk-related tyrosine protein kinase gene
-
Chow, L. M. et al. Two distinct protein isoforms are encoded by ntk, a csk-related tyrosine protein kinase gene. Oncogene 9, 3437-3448 (1994).
-
(1994)
Oncogene
, vol.9
, pp. 3437-3448
-
-
Chow, L.M.1
-
38
-
-
0026080883
-
Enhancement of T-cell responsiveness by the lymphocyte-specific tyrosine protein kinase p56lck
-
Abraham, N., Miceli, M. C., Parnes, J. R. & Veillette, A. Enhancement of T-cell responsiveness by the lymphocyte-specific tyrosine protein kinase p56lck. Nature 350, 62-66 (1991).
-
(1991)
Nature
, vol.350
, pp. 62-66
-
-
Abraham, N.1
Miceli, M.C.2
Parnes, J.R.3
Veillette, A.4
-
39
-
-
0035890037
-
Activation of NK cell-mediated cytotoxicity by a SAP-independent receptor of the CD2 family
-
Bouchon, A., Cella, M., Grierson, H. L., Cohen, J. I. & Colonna, M. Activation of NK cell-mediated cytotoxicity by a SAP-independent receptor of the CD2 family. J. Immunol. 167, 5517-5521 (2001).
-
(2001)
J. Immunol.
, vol.167
, pp. 5517-5521
-
-
Bouchon, A.1
Cella, M.2
Grierson, H.L.3
Cohen, J.I.4
Colonna, M.5
-
40
-
-
0029788103
-
Differential intrinsic enzymatic activity of Syk and Zap-70 protein-tyrosine kinases
-
Latour, S., Chow, L. M. & Veillette, A. Differential intrinsic enzymatic activity of Syk and Zap-70 protein-tyrosine kinases. J. Biol. Chem. 271, 22782-22790 (1996).
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 22782-22790
-
-
Latour, S.1
Chow, L.M.2
Veillette, A.3
-
41
-
-
60749124123
-
Influence of CRACC, a SLAM family receptor coupled to the adaptor EAT-2, on natural killer cell function
-
Cruz-Munoz, M. E., Dong, Z., Shi, X., Zhang, S. & Veillette, A. Influence of CRACC, a SLAM family receptor coupled to the adaptor EAT-2, on natural killer cell function. Nat. Immunol. 10, 297-305 (2009).
-
(2009)
Nat. Immunol.
, vol.10
, pp. 297-305
-
-
Cruz-Munoz, M.E.1
Dong, Z.2
Shi, X.3
Zhang, S.4
Veillette, A.5
-
42
-
-
84875368795
-
Multimolecular signaling complexes enable Syk-mediated signaling of CD36 internalization
-
Heit, B. et al. Multimolecular signaling complexes enable Syk-mediated signaling of CD36 internalization. Dev. Cell 24, 372-383 (2013).
-
(2013)
Dev. Cell
, vol.24
, pp. 372-383
-
-
Heit, B.1
-
43
-
-
84897050176
-
Methylation of the DNA/RNA-binding protein Kin17 by METTL22 affects its association with chromatin
-
Cloutier, P., Lavallée-Adam, M., Faubert, D., Blanchette, M. & Coulombe, B. Methylation of the DNA/RNA-binding protein Kin17 by METTL22 affects its association with chromatin. J. Proteomics 100, 115-124 (2014).
-
(2014)
J. Proteomics
, vol.100
, pp. 115-124
-
-
Cloutier, P.1
Lavallée-Adam, M.2
Faubert, D.3
Blanchette, M.4
Coulombe, B.5
-
44
-
-
0023737931
-
The CD4 and CD8 T cell surface antigens are associated with the internal membrane tyrosine-protein kinase p56lck
-
Veillette, A., Bookman, M. A., Horak, E. M. & Bolen, J. B. The CD4 and CD8 T cell surface antigens are associated with the internal membrane tyrosine-protein kinase p56lck. Cell 55, 301-308 (1988).
-
(1988)
Cell
, vol.55
, pp. 301-308
-
-
Veillette, A.1
Bookman, M.A.2
Horak, E.M.3
Bolen, J.B.4
-
45
-
-
48749084082
-
An international standardization programme towards the application of gene expression profiling in routine leukaemia diagnostics: The Microarray Innovations in LEukemia study prephase
-
Kohlmann, A. et al. An international standardization programme towards the application of gene expression profiling in routine leukaemia diagnostics: the Microarray Innovations in LEukemia study prephase. Br. J. Haematol. 142, 802-807 (2008).
-
(2008)
Br. J. Haematol.
, vol.142
, pp. 802-807
-
-
Kohlmann, A.1
-
46
-
-
84976874913
-
BloodSpot: A database of gene expression profiles and transcriptional programs for healthy and malignant haematopoiesis
-
Bagger, F. O. et al. BloodSpot: a database of gene expression profiles and transcriptional programs for healthy and malignant haematopoiesis. Nucleic Acids Res. 44 (D1), D917-D924 (2016).
-
(2016)
Nucleic Acids Res.
, vol.44
, Issue.D1
, pp. D917-D924
-
-
Bagger, F.O.1
-
47
-
-
79951494668
-
Initial genome sequencing and analysis of multiple myeloma
-
Chapman, M. A. et al. Initial genome sequencing and analysis of multiple myeloma. Nature 471, 467-472 (2011).
-
(2011)
Nature
, vol.471
, pp. 467-472
-
-
Chapman, M.A.1
|