-
1
-
-
85018734799
-
-
Geriat Med 2015; 53: 479-83.
-
(2015)
Geriat Med
, vol.53
, pp. 479-483
-
-
-
2
-
-
41649087328
-
Discovery of dapagliflozin: A potent, selective renal sodium-dependent glucose cotransporter 2 (SGLT2) inhibitor for the treatment of type 2 diabetes
-
Meng W, Ellsworth BA, Nirschl AA, McCann PJ, Patel M, Girotra RN, et al. Discovery of dapagliflozin: a potent, selective renal sodium-dependent glucose cotransporter 2 (SGLT2) inhibitor for the treatment of type 2 diabetes. J MedChem 2008;51: 1145-9.
-
(2008)
J MedChem
, vol.51
, pp. 1145-1149
-
-
Meng, W.1
Ellsworth, B.A.2
Nirschl, A.A.3
McCann, P.J.4
Patel, M.5
Girotra, R.N.6
-
3
-
-
48249146624
-
Dapagliflozin, a selective SGLT2 inhibitor, improves glucose homeostasis in normal and diabetic rats
-
Han S, Hagan DL, Taylor JR, Xin L, Meng W, Biller SA, et al. Dapagliflozin, a selective SGLT2 inhibitor, improves glucose homeostasis in normal and diabetic rats. Diabetes 2008; 57: 1723-9.
-
(2008)
Diabetes
, vol.57
, pp. 1723-1729
-
-
Han, S.1
Hagan, D.L.2
Taylor, J.R.3
Xin, L.4
Meng, W.5
Biller, S.A.6
-
4
-
-
84866003015
-
Dapagliflozin monotherapy in drug-naive patients with diabetes: A random-ized-controlled trial of low-dose range
-
Bailey CJ, Iqbal N, T joen C, List JF. Dapagliflozin monotherapy in drug-naive patients with diabetes: a random-ized-controlled trial of low-dose range. Diabetes Obes Metab 2012; 14: 951-9.
-
(2012)
Diabetes Obes Metab
, vol.14
, pp. 951-959
-
-
Bailey, C.J.1
Iqbal, N.2
Tjoen, C.3
List, J.F.4
-
5
-
-
84873960885
-
Dapagliflozin add-on to metformin in type 2 diabetes inadequately controlled with metformin: A randomized, double-blind, placebo-controlled 102-week trial
-
Bailey CJ, Gross JL, Hennicken D, Iqbal N, Mansfield TA, List JF. Dapagliflozin add-on to metformin in type 2 diabetes inadequately controlled with metformin: a randomized, double-blind, placebo-controlled 102-week trial. BMC Med 2013; 11:43.
-
(2013)
BMC Med
, vol.11
, pp. 43
-
-
Bailey, C.J.1
Gross, J.L.2
Hennicken, D.3
Iqbal, N.4
Mansfield, T.A.5
List, J.F.6
-
6
-
-
84914181817
-
Efficacy and safety of dapagliflozin monotherapy in Japanese patients with type 2 diabetes inadequately controlled by diet and exercise
-
Kaku K, Kiyosue A, Inoue S, Ueda N, Tokudome T, Yang J, et al. Efficacy and safety of dapagliflozin monotherapy in Japanese patients with type 2 diabetes inadequately controlled by diet and exercise. Diabetes Obes Metab 2014; 16: 1102-10.
-
(2014)
Diabetes Obes Metab
, vol.16
, pp. 1102-1110
-
-
Kaku, K.1
Kiyosue, A.2
Inoue, S.3
Ueda, N.4
Tokudome, T.5
Yang, J.6
-
7
-
-
84915738768
-
Dapagliflozin as monotherapy or combination therapy in Japanese patients with type 2 diabetes: An open-label study
-
Kaku K, Maegawa H, Tanizawa Y, Kiyosue A, Ide Y, Tokudome T, et al. Dapagliflozin as monotherapy or combination therapy in Japanese patients with type 2 diabetes: an open-label study. Diabetes Ther 2014; 5: 415-33.
-
(2014)
Diabetes Ther
, vol.5
, pp. 415-433
-
-
Kaku, K.1
Maegawa, H.2
Tanizawa, Y.3
Kiyosue, A.4
Ide, Y.5
Tokudome, T.6
-
8
-
-
84876322415
-
Inhibition of the sodium glucose co-transporter-2: Its beneficial action and potential combination therapy for type 2 diabetes mellitus
-
Chen LH, Leung PS. Inhibition of the sodium glucose co-transporter-2: its beneficial action and potential combination therapy for type 2 diabetes mellitus. Diabetes Obes Metab 2013; 15: 392-402.
-
(2013)
Diabetes Obes Metab
, vol.15
, pp. 392-402
-
-
Chen, L.H.1
Leung, P.S.2
-
9
-
-
79951897566
-
Pharmacokinetics and pharmacodynamics of dapagliflozin, a novel selective inhibitor of sodium-glucose co-transporter type 2, in Japanese subjects without and with type 2 diabetes mellitus
-
Kasichayanula S, Chang M, Hasegawa M, Liu X, Yamahira N, LaCreta FP, et al. Pharmacokinetics and pharmacodynamics of dapagliflozin, a novel selective inhibitor of sodium-glucose co-transporter type 2, in Japanese subjects without and with type 2 diabetes mellitus. Diabetes Obes Metab 2011; 13:357-65.
-
(2011)
Diabetes Obes Metab
, vol.13
, pp. 357-365
-
-
Kasichayanula, S.1
Chang, M.2
Hasegawa, M.3
Liu, X.4
Yamahira, N.5
LaCreta, F.P.6
-
10
-
-
84876335563
-
Efficacy and safety of dapagliflozin as a monotherapy for type 2 diabetes mellitus in Japanese patients with inadequate glycaemic control: A phase II multicentre, randomized, double-blind, placebo-controlled trial
-
Kaku K, Inoue S, Matsuoka O, Kiyosue A, Azuma H, Hayashi N, et al. Efficacy and safety of dapagliflozin as a monotherapy for type 2 diabetes mellitus in Japanese patients with inadequate glycaemic control: a phase II multicentre, randomized, double-blind, placebo-controlled trial. Diabetes Obes Metab 2013; 15: 432-40.
-
(2013)
Diabetes Obes Metab
, vol.15
, pp. 432-440
-
-
Kaku, K.1
Inoue, S.2
Matsuoka, O.3
Kiyosue, A.4
Azuma, H.5
Hayashi, N.6
-
11
-
-
84892488179
-
Dapagliflozin in patients with type 2 diabetes receiving high doses of insulin: Efficacy and safety over 2 years
-
Wilding JP, Woo V, Rohwedder K, Sugg J, Parikh S; Dapagliflozin 006 Study Group. Dapagliflozin in patients with type 2 diabetes receiving high doses of insulin: efficacy and safety over 2 years. Diabetes Obes Metab 2014; 16: 124-36.
-
(2014)
Diabetes Obes Metab
, vol.16
, pp. 124-136
-
-
Wilding, J.P.1
Woo, V.2
Rohwedder, K.3
Sugg, J.4
Parikh, S.5
-
12
-
-
84928426587
-
Long-term glycaemic response and tolerability of dapagliflozin versus a sulpho-nylurea as add-on therapy to metformin in patients with type 2 diabetes: 4-year data
-
Del Prato S, Nauck M, Durán-Garcia S, Maffei L, Rohwedder K, Theuerkauf A, et al. Long-term glycaemic response and tolerability of dapagliflozin versus a sulpho-nylurea as add-on therapy to metformin in patients with type 2 diabetes: 4-year data. Diabetes Obes Metab 2015; 17: 581-90.
-
(2015)
Diabetes Obes Metab
, vol.17
, pp. 581-590
-
-
Del Prato, S.1
Nauck, M.2
Durán-Garcia, S.3
Maffei, L.4
Rohwedder, K.5
Theuerkauf, A.6
-
13
-
-
84870989233
-
Diabetes in older adults: A consensus report
-
Kirkman MS, Briscoe VJ, Clark N, Florez H, Haas LB, Halter JB, et al. Diabetes in older adults: a consensus report. J Am Geriatr Soc 2012; 60: 2342-56.
-
(2012)
J Am Geriatr Soc
, vol.60
, pp. 2342-2356
-
-
Kirkman, M.S.1
Briscoe, V.J.2
Clark, N.3
Florez, H.4
Haas, L.B.5
Halter, J.B.6
-
14
-
-
84934288630
-
Safety profile of dapagliflozin for type 2 diabetes: Pooled analysis of clinical studies for overall safety and rare events
-
Ptaszynska A, Johnsson KM, Parikh SJ, de Bruin TW, Apanovitch AM, List JF. Safety profile of dapagliflozin for type 2 diabetes: pooled analysis of clinical studies for overall safety and rare events. Drug Saf 2014; 37: 815-29.
-
(2014)
Drug Saf
, vol.37
, pp. 815-829
-
-
Ptaszynska, A.1
Johnsson, K.M.2
Parikh, S.J.3
De Bruin, T.W.4
Apanovitch, A.M.5
List, J.F.6
-
15
-
-
84908066747
-
Update on developments with SGLT2 inhibitors in the management of type 2 diabetes
-
Nauck MA. Update on developments with SGLT2 inhibitors in the management of type 2 diabetes. Drug Des Devel Ther 2014; 8: 1335-80.
-
(2014)
Drug des Devel Ther
, vol.8
, pp. 1335-1380
-
-
Nauck, M.A.1
-
16
-
-
65349196064
-
Sodium-glucose cotransport inhibition with dapagliflozin in type 2 diabetes
-
List JF, Woo V, Morales E, Tang W, Fiedorek FT. Sodium-glucose cotransport inhibition with dapagliflozin in type 2 diabetes. Diabetes Care 2009; 32: 650-7.
-
(2009)
Diabetes Care
, vol.32
, pp. 650-657
-
-
List, J.F.1
Woo, V.2
Morales, E.3
Tang, W.4
Fiedorek, F.T.5
-
17
-
-
0031969717
-
Perceived symptoms of hypoglycaemia in elderly type 2 diabetic patients treated with insulin
-
Jaap AJ, Jones GC, McCrimmon RJ, Deary IJ, Frier BM. Perceived symptoms of hypoglycaemia in elderly type 2 diabetic patients treated with insulin. Diabet Med 1998; 15:398-401.
-
(1998)
Diabet Med
, vol.15
, pp. 398-401
-
-
Jaap, A.J.1
Jones, G.C.2
McCrimmon, R.J.3
Deary, I.J.4
Frier, B.M.5
-
18
-
-
2442606195
-
Factors affecting hypoglycemia awareness in insulin-treated type 2 diabetes: The Diabetes Outcomes in Veterans Study (DOVES)
-
Murata GH, Duckworth WC, Shah JH, Wendel CS, Hoffman RM; Diabetes Outcomes in Veterans Study. Factors affecting hypoglycemia awareness in insulin-treated type 2 diabetes: The Diabetes Outcomes in Veterans Study (DOVES). Diabetes Res Clin Pract 2004; 65: 61-7.
-
(2004)
Diabetes Res Clin Pract
, vol.65
, pp. 61-67
-
-
Murata, G.H.1
Duckworth, W.C.2
Shah, J.H.3
Wendel, C.S.4
Hoffman, R.M.5
-
19
-
-
84898791935
-
Efficacy and safety of sodium glucose co-transport-2 inhibitors in type 2 diabetes: A meta-analysis of randomized clinical trials
-
Monami M, Nardini C, Mannucci E. Efficacy and safety of sodium glucose co-transport-2 inhibitors in type 2 diabetes: a meta-analysis of randomized clinical trials. Diabetes Obes Metab 2014; 16: 457-66.
-
(2014)
Diabetes Obes Metab
, vol.16
, pp. 457-466
-
-
Monami, M.1
Nardini, C.2
Mannucci, E.3
-
20
-
-
84882251091
-
Sodium-glucose cotransporter 2 inhibitors for type 2 diabetes: A systematic review and meta-analysis
-
Vasilakou D, Karagiannis T, Athanasiadou E, Mainou M, Liakos A, Bekiari E, et al. Sodium-glucose cotransporter 2 inhibitors for type 2 diabetes: a systematic review and meta-analysis. Ann Intern Med 2013; 159: 262-74.
-
(2013)
Ann Intern Med
, vol.159
, pp. 262-274
-
-
Vasilakou, D.1
Karagiannis, T.2
Athanasiadou, E.3
Mainou, M.4
Liakos, A.5
Bekiari, E.6
-
21
-
-
84897509165
-
-
US Food and Drug Administration Advisory committee briefing document
-
US Food and Drug Administration, Endocrinologie and Metabolic Drugs Advisory Committee. Advisory committee briefing document. 2013.
-
(2013)
Endocrinologie and Metabolic Drugs Advisory Committee
-
-
-
22
-
-
84962439093
-
Euglycemic diabetic ketoacidosis: A predictable, detectable, and preventable safety concern with SGLT2 inhibitors
-
Rosenstock J, Ferrannini E. Euglycemic diabetic ketoacidosis: a predictable, detectable, and preventable safety concern with SGLT2 inhibitors. Diabetes Care 2015; 38: 1638-42.
-
(2015)
Diabetes Care
, vol.38
, pp. 1638-1642
-
-
Rosenstock, J.1
Ferrannini, E.2
-
23
-
-
84959366596
-
Euglycemic diabetic ketoacidosis induced by SGLT2 inhibitors: Possible mechanism and contributing factors
-
Ogawa W, Sakaguchi K. Euglycemic diabetic ketoacidosis induced by SGLT2 inhibitors: possible mechanism and contributing factors. J Diabetes Investig 2016; 7: 135-8.
-
(2016)
J Diabetes Investig
, vol.7
, pp. 135-138
-
-
Ogawa, W.1
Sakaguchi, K.2
-
26
-
-
84976421792
-
Long-term safety of dapagliflozin in older patients with type 2 diabetes mellitus: A pooled analysis of phase II b/III studies
-
Fioretto P, Mansfield TA, Ptaszynska A, Yavin Y, Johnsson E, Parikh S. Long-term safety of dapagliflozin in older patients with type 2 diabetes mellitus: a pooled analysis of phase II b/III studies. Drugs Aging 2016; 33: 511-22.
-
(2016)
Drugs Aging
, vol.33
, pp. 511-522
-
-
Fioretto, P.1
Mansfield, T.A.2
Ptaszynska, A.3
Yavin, Y.4
Johnsson, E.5
Parikh, S.6
|