메뉴 건너뛰기




Volumn 45, Issue 3, 2017, Pages 357-384

Investigation of the safety and efficacy of dapagliflozin for type 2 diabetes in elderly patients - Final report of the dapagliflozin observational study (DIANTHUS Study)

Author keywords

Adverse reaction; Dapagliflozin; Elderly patients; SGLT2 inhibitor; Use result survey

Indexed keywords

DAPAGLIFLOZIN;

EID: 85018759408     PISSN: 03863603     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (3)

References (26)
  • 1
    • 85018734799 scopus 로고    scopus 로고
    • Geriat Med 2015; 53: 479-83.
    • (2015) Geriat Med , vol.53 , pp. 479-483
  • 2
    • 41649087328 scopus 로고    scopus 로고
    • Discovery of dapagliflozin: A potent, selective renal sodium-dependent glucose cotransporter 2 (SGLT2) inhibitor for the treatment of type 2 diabetes
    • Meng W, Ellsworth BA, Nirschl AA, McCann PJ, Patel M, Girotra RN, et al. Discovery of dapagliflozin: a potent, selective renal sodium-dependent glucose cotransporter 2 (SGLT2) inhibitor for the treatment of type 2 diabetes. J MedChem 2008;51: 1145-9.
    • (2008) J MedChem , vol.51 , pp. 1145-1149
    • Meng, W.1    Ellsworth, B.A.2    Nirschl, A.A.3    McCann, P.J.4    Patel, M.5    Girotra, R.N.6
  • 3
    • 48249146624 scopus 로고    scopus 로고
    • Dapagliflozin, a selective SGLT2 inhibitor, improves glucose homeostasis in normal and diabetic rats
    • Han S, Hagan DL, Taylor JR, Xin L, Meng W, Biller SA, et al. Dapagliflozin, a selective SGLT2 inhibitor, improves glucose homeostasis in normal and diabetic rats. Diabetes 2008; 57: 1723-9.
    • (2008) Diabetes , vol.57 , pp. 1723-1729
    • Han, S.1    Hagan, D.L.2    Taylor, J.R.3    Xin, L.4    Meng, W.5    Biller, S.A.6
  • 4
    • 84866003015 scopus 로고    scopus 로고
    • Dapagliflozin monotherapy in drug-naive patients with diabetes: A random-ized-controlled trial of low-dose range
    • Bailey CJ, Iqbal N, T joen C, List JF. Dapagliflozin monotherapy in drug-naive patients with diabetes: a random-ized-controlled trial of low-dose range. Diabetes Obes Metab 2012; 14: 951-9.
    • (2012) Diabetes Obes Metab , vol.14 , pp. 951-959
    • Bailey, C.J.1    Iqbal, N.2    Tjoen, C.3    List, J.F.4
  • 5
    • 84873960885 scopus 로고    scopus 로고
    • Dapagliflozin add-on to metformin in type 2 diabetes inadequately controlled with metformin: A randomized, double-blind, placebo-controlled 102-week trial
    • Bailey CJ, Gross JL, Hennicken D, Iqbal N, Mansfield TA, List JF. Dapagliflozin add-on to metformin in type 2 diabetes inadequately controlled with metformin: a randomized, double-blind, placebo-controlled 102-week trial. BMC Med 2013; 11:43.
    • (2013) BMC Med , vol.11 , pp. 43
    • Bailey, C.J.1    Gross, J.L.2    Hennicken, D.3    Iqbal, N.4    Mansfield, T.A.5    List, J.F.6
  • 6
    • 84914181817 scopus 로고    scopus 로고
    • Efficacy and safety of dapagliflozin monotherapy in Japanese patients with type 2 diabetes inadequately controlled by diet and exercise
    • Kaku K, Kiyosue A, Inoue S, Ueda N, Tokudome T, Yang J, et al. Efficacy and safety of dapagliflozin monotherapy in Japanese patients with type 2 diabetes inadequately controlled by diet and exercise. Diabetes Obes Metab 2014; 16: 1102-10.
    • (2014) Diabetes Obes Metab , vol.16 , pp. 1102-1110
    • Kaku, K.1    Kiyosue, A.2    Inoue, S.3    Ueda, N.4    Tokudome, T.5    Yang, J.6
  • 7
    • 84915738768 scopus 로고    scopus 로고
    • Dapagliflozin as monotherapy or combination therapy in Japanese patients with type 2 diabetes: An open-label study
    • Kaku K, Maegawa H, Tanizawa Y, Kiyosue A, Ide Y, Tokudome T, et al. Dapagliflozin as monotherapy or combination therapy in Japanese patients with type 2 diabetes: an open-label study. Diabetes Ther 2014; 5: 415-33.
    • (2014) Diabetes Ther , vol.5 , pp. 415-433
    • Kaku, K.1    Maegawa, H.2    Tanizawa, Y.3    Kiyosue, A.4    Ide, Y.5    Tokudome, T.6
  • 8
    • 84876322415 scopus 로고    scopus 로고
    • Inhibition of the sodium glucose co-transporter-2: Its beneficial action and potential combination therapy for type 2 diabetes mellitus
    • Chen LH, Leung PS. Inhibition of the sodium glucose co-transporter-2: its beneficial action and potential combination therapy for type 2 diabetes mellitus. Diabetes Obes Metab 2013; 15: 392-402.
    • (2013) Diabetes Obes Metab , vol.15 , pp. 392-402
    • Chen, L.H.1    Leung, P.S.2
  • 9
    • 79951897566 scopus 로고    scopus 로고
    • Pharmacokinetics and pharmacodynamics of dapagliflozin, a novel selective inhibitor of sodium-glucose co-transporter type 2, in Japanese subjects without and with type 2 diabetes mellitus
    • Kasichayanula S, Chang M, Hasegawa M, Liu X, Yamahira N, LaCreta FP, et al. Pharmacokinetics and pharmacodynamics of dapagliflozin, a novel selective inhibitor of sodium-glucose co-transporter type 2, in Japanese subjects without and with type 2 diabetes mellitus. Diabetes Obes Metab 2011; 13:357-65.
    • (2011) Diabetes Obes Metab , vol.13 , pp. 357-365
    • Kasichayanula, S.1    Chang, M.2    Hasegawa, M.3    Liu, X.4    Yamahira, N.5    LaCreta, F.P.6
  • 10
    • 84876335563 scopus 로고    scopus 로고
    • Efficacy and safety of dapagliflozin as a monotherapy for type 2 diabetes mellitus in Japanese patients with inadequate glycaemic control: A phase II multicentre, randomized, double-blind, placebo-controlled trial
    • Kaku K, Inoue S, Matsuoka O, Kiyosue A, Azuma H, Hayashi N, et al. Efficacy and safety of dapagliflozin as a monotherapy for type 2 diabetes mellitus in Japanese patients with inadequate glycaemic control: a phase II multicentre, randomized, double-blind, placebo-controlled trial. Diabetes Obes Metab 2013; 15: 432-40.
    • (2013) Diabetes Obes Metab , vol.15 , pp. 432-440
    • Kaku, K.1    Inoue, S.2    Matsuoka, O.3    Kiyosue, A.4    Azuma, H.5    Hayashi, N.6
  • 11
    • 84892488179 scopus 로고    scopus 로고
    • Dapagliflozin in patients with type 2 diabetes receiving high doses of insulin: Efficacy and safety over 2 years
    • Wilding JP, Woo V, Rohwedder K, Sugg J, Parikh S; Dapagliflozin 006 Study Group. Dapagliflozin in patients with type 2 diabetes receiving high doses of insulin: efficacy and safety over 2 years. Diabetes Obes Metab 2014; 16: 124-36.
    • (2014) Diabetes Obes Metab , vol.16 , pp. 124-136
    • Wilding, J.P.1    Woo, V.2    Rohwedder, K.3    Sugg, J.4    Parikh, S.5
  • 12
    • 84928426587 scopus 로고    scopus 로고
    • Long-term glycaemic response and tolerability of dapagliflozin versus a sulpho-nylurea as add-on therapy to metformin in patients with type 2 diabetes: 4-year data
    • Del Prato S, Nauck M, Durán-Garcia S, Maffei L, Rohwedder K, Theuerkauf A, et al. Long-term glycaemic response and tolerability of dapagliflozin versus a sulpho-nylurea as add-on therapy to metformin in patients with type 2 diabetes: 4-year data. Diabetes Obes Metab 2015; 17: 581-90.
    • (2015) Diabetes Obes Metab , vol.17 , pp. 581-590
    • Del Prato, S.1    Nauck, M.2    Durán-Garcia, S.3    Maffei, L.4    Rohwedder, K.5    Theuerkauf, A.6
  • 14
    • 84934288630 scopus 로고    scopus 로고
    • Safety profile of dapagliflozin for type 2 diabetes: Pooled analysis of clinical studies for overall safety and rare events
    • Ptaszynska A, Johnsson KM, Parikh SJ, de Bruin TW, Apanovitch AM, List JF. Safety profile of dapagliflozin for type 2 diabetes: pooled analysis of clinical studies for overall safety and rare events. Drug Saf 2014; 37: 815-29.
    • (2014) Drug Saf , vol.37 , pp. 815-829
    • Ptaszynska, A.1    Johnsson, K.M.2    Parikh, S.J.3    De Bruin, T.W.4    Apanovitch, A.M.5    List, J.F.6
  • 15
    • 84908066747 scopus 로고    scopus 로고
    • Update on developments with SGLT2 inhibitors in the management of type 2 diabetes
    • Nauck MA. Update on developments with SGLT2 inhibitors in the management of type 2 diabetes. Drug Des Devel Ther 2014; 8: 1335-80.
    • (2014) Drug des Devel Ther , vol.8 , pp. 1335-1380
    • Nauck, M.A.1
  • 16
    • 65349196064 scopus 로고    scopus 로고
    • Sodium-glucose cotransport inhibition with dapagliflozin in type 2 diabetes
    • List JF, Woo V, Morales E, Tang W, Fiedorek FT. Sodium-glucose cotransport inhibition with dapagliflozin in type 2 diabetes. Diabetes Care 2009; 32: 650-7.
    • (2009) Diabetes Care , vol.32 , pp. 650-657
    • List, J.F.1    Woo, V.2    Morales, E.3    Tang, W.4    Fiedorek, F.T.5
  • 17
    • 0031969717 scopus 로고    scopus 로고
    • Perceived symptoms of hypoglycaemia in elderly type 2 diabetic patients treated with insulin
    • Jaap AJ, Jones GC, McCrimmon RJ, Deary IJ, Frier BM. Perceived symptoms of hypoglycaemia in elderly type 2 diabetic patients treated with insulin. Diabet Med 1998; 15:398-401.
    • (1998) Diabet Med , vol.15 , pp. 398-401
    • Jaap, A.J.1    Jones, G.C.2    McCrimmon, R.J.3    Deary, I.J.4    Frier, B.M.5
  • 18
    • 2442606195 scopus 로고    scopus 로고
    • Factors affecting hypoglycemia awareness in insulin-treated type 2 diabetes: The Diabetes Outcomes in Veterans Study (DOVES)
    • Murata GH, Duckworth WC, Shah JH, Wendel CS, Hoffman RM; Diabetes Outcomes in Veterans Study. Factors affecting hypoglycemia awareness in insulin-treated type 2 diabetes: The Diabetes Outcomes in Veterans Study (DOVES). Diabetes Res Clin Pract 2004; 65: 61-7.
    • (2004) Diabetes Res Clin Pract , vol.65 , pp. 61-67
    • Murata, G.H.1    Duckworth, W.C.2    Shah, J.H.3    Wendel, C.S.4    Hoffman, R.M.5
  • 19
    • 84898791935 scopus 로고    scopus 로고
    • Efficacy and safety of sodium glucose co-transport-2 inhibitors in type 2 diabetes: A meta-analysis of randomized clinical trials
    • Monami M, Nardini C, Mannucci E. Efficacy and safety of sodium glucose co-transport-2 inhibitors in type 2 diabetes: a meta-analysis of randomized clinical trials. Diabetes Obes Metab 2014; 16: 457-66.
    • (2014) Diabetes Obes Metab , vol.16 , pp. 457-466
    • Monami, M.1    Nardini, C.2    Mannucci, E.3
  • 20
    • 84882251091 scopus 로고    scopus 로고
    • Sodium-glucose cotransporter 2 inhibitors for type 2 diabetes: A systematic review and meta-analysis
    • Vasilakou D, Karagiannis T, Athanasiadou E, Mainou M, Liakos A, Bekiari E, et al. Sodium-glucose cotransporter 2 inhibitors for type 2 diabetes: a systematic review and meta-analysis. Ann Intern Med 2013; 159: 262-74.
    • (2013) Ann Intern Med , vol.159 , pp. 262-274
    • Vasilakou, D.1    Karagiannis, T.2    Athanasiadou, E.3    Mainou, M.4    Liakos, A.5    Bekiari, E.6
  • 21
    • 84897509165 scopus 로고    scopus 로고
    • US Food and Drug Administration Advisory committee briefing document
    • US Food and Drug Administration, Endocrinologie and Metabolic Drugs Advisory Committee. Advisory committee briefing document. 2013.
    • (2013) Endocrinologie and Metabolic Drugs Advisory Committee
  • 22
    • 84962439093 scopus 로고    scopus 로고
    • Euglycemic diabetic ketoacidosis: A predictable, detectable, and preventable safety concern with SGLT2 inhibitors
    • Rosenstock J, Ferrannini E. Euglycemic diabetic ketoacidosis: a predictable, detectable, and preventable safety concern with SGLT2 inhibitors. Diabetes Care 2015; 38: 1638-42.
    • (2015) Diabetes Care , vol.38 , pp. 1638-1642
    • Rosenstock, J.1    Ferrannini, E.2
  • 23
    • 84959366596 scopus 로고    scopus 로고
    • Euglycemic diabetic ketoacidosis induced by SGLT2 inhibitors: Possible mechanism and contributing factors
    • Ogawa W, Sakaguchi K. Euglycemic diabetic ketoacidosis induced by SGLT2 inhibitors: possible mechanism and contributing factors. J Diabetes Investig 2016; 7: 135-8.
    • (2016) J Diabetes Investig , vol.7 , pp. 135-138
    • Ogawa, W.1    Sakaguchi, K.2
  • 26
    • 84976421792 scopus 로고    scopus 로고
    • Long-term safety of dapagliflozin in older patients with type 2 diabetes mellitus: A pooled analysis of phase II b/III studies
    • Fioretto P, Mansfield TA, Ptaszynska A, Yavin Y, Johnsson E, Parikh S. Long-term safety of dapagliflozin in older patients with type 2 diabetes mellitus: a pooled analysis of phase II b/III studies. Drugs Aging 2016; 33: 511-22.
    • (2016) Drugs Aging , vol.33 , pp. 511-522
    • Fioretto, P.1    Mansfield, T.A.2    Ptaszynska, A.3    Yavin, Y.4    Johnsson, E.5    Parikh, S.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.