-
1
-
-
84880330155
-
HIV-1 eradication strategies: Design and assessment
-
Jul 8 PMID: 23698561
-
SilicianoJD, SilicianoRF. HIV-1 eradication strategies: design and assessment. CurrOpin HIV AIDS. 2013 Jul; 8(4):318-25. https://doi.org/10.1097/COH.0b013e328361eaca PMID: 23698561
-
(2013)
CurrOpin HIV AIDS
, vol.4
, pp. 318-325
-
-
Siliciano, J.D.1
Siliciano, R.F.2
-
2
-
-
84891827613
-
Emerging strategies todeplete the HIV reservoir
-
Feb 27
-
Archin NM, Margolis DM. Emerging strategies todeplete the HIV reservoir. CurrOpin Infect Dis. 2014 Feb; 27(1):29-35
-
(2014)
Curr Opin Infect Dis
, vol.1
, pp. 29-35
-
-
Archin, N.M.1
Margolis, D.M.2
-
3
-
-
84864203255
-
Administration of vorinostat disrupts HIV-1 latency in patients on antiretroviral therapy
-
Jul 25 PMID: 22837004
-
Archin NM, Liberty AL, Kashuba AD, Choudhary SK, Kuruc JD, Crooks AM, et al.Administration of vorinostat disrupts HIV-1 latency in patients on antiretroviral therapy. Nature. 2012 Jul 25; 487(7408):482-5. https://doi.org/10.1038/nature11286 PMID: 22837004
-
(2012)
Nature
, vol.487
, Issue.7408
, pp. 482-485
-
-
Archin, N.M.1
Liberty, A.L.2
Kashuba, A.D.3
Choudhary, S.K.4
Kuruc, J.D.5
Crooks, A.M.6
-
4
-
-
84912122037
-
Activation of HIV transcription with short-course vorinostat in HIV-infected patients on suppressive antiretroviral therapy
-
Nov13
-
Elliott JH, Wightman F, Solomon A, Ghneim K, Ahlers J, Cameron MJ, et al.Activation of HIV transcription with short-course vorinostat in HIV-infected patients on suppressive antiretroviral therapy. PLoSPathog. 2014 Nov13; 10(10):e1004473
-
(2014)
PLoSPathog
, vol.10
, Issue.10
, pp. e1004473
-
-
Elliott, J.H.1
Wightman, F.2
Solomon, A.3
Ghneim, K.4
Ahlers, J.5
Cameron, M.J.6
-
5
-
-
84911460971
-
Panobinostat, a histone deacetylase inhibitor, for latent-virus reactivation in HIV-infected patients on suppressive antiretroviral therapy: A phase 1/2, single group, clinical trial
-
Oct 1
-
Rasmussen TA, Tolstrup M, Brinkmann CR, Olesen R, Erikstrup C, Solomon A, et al. Panobinostat, a histone deacetylase inhibitor, for latent-virus reactivation in HIV-infected patients on suppressive antiretroviral therapy: a phase 1/2, single group, clinical trial. Lancet HIV. 2014Oct; 1(1):e13-21
-
(2014)
Lancet HIV.
, vol.1
, pp. e13-21
-
-
Rasmussen, T.A.1
Tolstrup, M.2
Brinkmann, C.R.3
Olesen, R.4
Erikstrup, C.5
Solomon, A.6
-
6
-
-
84943557984
-
The DepsipeptideRomidepsin Reverses HIV-1 Latency in Vivo
-
Sep 17
-
Sogaard OS, Graversen ME, Leth S, Olesen R, Brinkmann CR, Nissen SK, et al. The DepsipeptideRomidepsin Reverses HIV-1 Latency In Vivo. PLoSPathog. 2015 Sep 17; 11(9):e1005142
-
(2015)
PLoSPathog
, vol.11
, Issue.9
, pp. e1005142
-
-
Sogaard, O.S.1
Graversen, M.E.2
Leth, S.3
Olesen, R.4
Brinkmann, C.R.5
Nissen, S.K.6
-
7
-
-
84984799753
-
Histone deacetylase inhibitors enhance CD4 T cell susceptibility Tonk cell killing but reduce nk cell function
-
Aug 16
-
Pace M, Williams J, Kurioka A, Gerry AB, Jakobsen B, Klenerman P,et al. Histone Deacetylase Inhibitors Enhance CD4 T Cell Susceptibility toNK Cell Killing but Reduce NK Cell Function. PLoSPathog. 2016 Aug 16; 12(8):e1005782
-
(2016)
PLoSPathog
, vol.12
, Issue.8
, pp. e1005782
-
-
Pace, M.1
Williams, J.2
Kurioka, A.3
Gerry, A.B.4
Jakobsen, B.5
Klenerman, P.6
-
8
-
-
84992166423
-
HIV Latency-reversing agents have diverse effects on natural killer cell function
-
in press
-
GarridoC, Spivak AM, Soriano-Sarabia N, Checkley MA, Barker E, Karn J, et al. HIV Latency-Reversing Agents Have Diverse Effects on Natural Killer Cell Function. Front Immunol in press 2016
-
(2016)
Front Immunol
-
-
Garrido, C.1
Spivak, A.M.2
Soriano-Sarabia, N.3
Ma, C.4
Barker, E.5
Karn, J.6
-
9
-
-
84863378890
-
Histone/protein deacetylases and T-cell immune responses
-
Mar 15 PMID: 22246031
-
Akimova T, Beier UH, LiuY, Wang L, Hancock WW. Histone/protein deacetylases and T-cell immune responses. Blood. 2012 Mar 15; 119(11):2443-51. https://doi.org/10.1182/blood-2011-10-292003 PMID: 22246031
-
(2012)
Blood
, vol.119
, Issue.11
, pp. 2443-2451
-
-
Akimova, T.1
Beier, U.H.2
Liu, Y.3
Wang, L.4
Hancock, W.W.5
-
10
-
-
84912530131
-
Histone deacetylase inhibitors impair the elimination of HIV-infected cells by cytotoxic T-lymphocytes
-
Aug 14
-
Jones RB, OConnor R, Mueller S, Foley M, SzetoGL, Karel D,et al. Histone deacetylase inhibitors impair the elimination of HIV-infected cells by cytotoxic T-lymphocytes. PLoSPathog. 2014 Aug 14; 10 (8):e1004287
-
(2014)
PLoSPathog
, vol.10
, Issue.8
, pp. e1004287
-
-
Jones, R.B.1
Oconnor, R.2
Mueller, S.3
Foley, M.4
Szeto, G.L.5
Karel, D.6
-
11
-
-
84964301410
-
The effect of latency reversal agents on primary cd8+ t cells: Implications for shock and kill strategies for human immunodeficiency virus eradication
-
Jun PMID: 27428432
-
Walker-Sperling VE, Pohlmeyer CW, Tarwater PM, Blankson JN. The Effect of Latency Reversal Agents on Primary CD8+ T Cells: Implications for Shock and Kill Strategies for Human Immunodeficiency Virus Eradication. EBioMedicine. 2016 Jun; 8:217-29. https://doi.org/10.1016/j.ebiom.2016.04. 019 PMID: 27428432
-
(2016)
EBioMedicine
, vol.8
, pp. 217-229
-
-
Walker-Sperling, V.E.1
Pohlmeyer, C.W.2
Tarwater, P.M.3
Blankson, J.N.4
-
12
-
-
84982683043
-
The differential short-and longterm effects of HIV-1 latency-reversing agents on T cell function
-
Aug 2 PMID: 27480951
-
Clutton G, XuY, Baldoni PL, Mollan KR, Kirchherr J, Newhard W, et al. The differential short-and longterm effects of HIV-1 latency-reversing agents on T cell function. Sci Rep. 2016 Aug 2; 6:30749. https:// doi.org/10.1038/srep30749 PMID: 27480951
-
(2016)
Sci Rep
, vol.6
, pp. 30749
-
-
Clutton, G.1
Xu, Y.2
Baldoni, P.L.3
Mollan, K.R.4
Kirchherr, J.5
Newhard, W.6
-
13
-
-
84906331211
-
The histone deacetylase inhibitor vorinostat (SAHA) increases the susceptibility of uninfected CD4+ T cells toHIV by increasing the kinetics and efficiency of postentry viral events
-
Sep 88 PMID: 25008921
-
Lucera MB, Tilton CA, MaoH, Dobrowolski C, Tabler CO, Haqqani AA, et al. The histone deacetylase inhibitor vorinostat (SAHA) increases the susceptibility of uninfected CD4+ T cells toHIV by increasing the kinetics and efficiency of postentry viral events. J Virol. 2014 Sep; 88(18):10803-12 https://doi.org/ 10.1128/JVI.00320-14 PMID: 25008921
-
(2014)
J Virol
, vol.18
, pp. 10803-10812
-
-
Lucera, M.B.1
Tilton, C.A.2
Mao, H.3
Dobrowolski, C.4
Tabler, C.O.5
Haqqani, A.A.6
-
14
-
-
84928986546
-
Ex vivoanalysis identifies effective HIV-1 latency-reversing drug combinations
-
May 125 PMID: 25822022
-
Laird GM, Bullen CK, Rosenbloom DI, Martin AR, Hill AL, Durand CM, et al. Ex vivoanalysis identifies effective HIV-1 latency-reversing drug combinations. J Clin Invest. 2015 May; 125(5):1901-12 https:// doi.org/10.1172/JCI80142 PMID: 25822022
-
(2015)
J Clin Invest
, vol.5
, pp. 1901-1912
-
-
Laird, G.M.1
Bullen, C.K.2
Rosenbloom, D.I.3
Martin, A.R.4
Hill, A.L.5
Durand, C.M.6
-
15
-
-
84938795129
-
An in-depth comparison of latency-reversing agent combinations in various in vitroand ex vivohiv-1 latency models identified bryostatin-1+jq1 and ingenol-b+jq1 topotently reactivate viral gene expression
-
Jul 30
-
Darcis G, Kula A, Bouchat S, Fujinaga K, Corazza F, Ait-Ammar A, et al. An In-Depth Comparison of Latency-Reversing Agent Combinations in Various In Vitroand Ex VivoHIV-1 Latency Models Identified Bryostatin-1+JQ1 and Ingenol-B+JQ1 toPotently Reactivate Viral Gene Expression. PLoSPathog. 2015 Jul 30; 11(7):e1005063
-
(2015)
PLoSPathog
, vol.11
, Issue.7
, pp. e1005063
-
-
Darcis, G.1
Kula, A.2
Bouchat, S.3
Fujinaga, K.4
Corazza, F.5
Ait-Ammar, A.6
-
16
-
-
84938786056
-
Progress and challenges in the use of latent HIV-1 reactivating agents
-
Shang H, Ding J, YuS, WuT, Zhang Q, Liang F. Progress and challenges in the use of latent HIV-1 reactivating agents. ActaPharmacologicaSinica. 2015; 36(8):908-916
-
(2015)
ActaPharmacologicaSinica
, vol.36
, Issue.8
, pp. 908-916
-
-
Shang, H.1
Ding, J.2
Yu, S.3
Wu, T.4
Zhang, Q.5
Liang, F.6
-
17
-
-
84907288256
-
Reactivation of latent HIV-1 by new semi-synthetic ingenol esters
-
PandeloJose D, Bartholomeeusen K, da Cunha RD, AbreuCM, Glinski J, da Costa TB, et al. Reactivation of latent HIV-1 by new semi-synthetic ingenol esters. Virology. 2014; 0:328-339
-
(2014)
Virology
, pp. 328-339
-
-
PandeloJose, D.1
Bartholomeeusen, K.2
Da Cunha, R.D.3
Abreu, C.M.4
Glinski, J.5
Da Costa, T.B.6
-
18
-
-
15444360575
-
Upregulation of HIV-1 replication in chronically infected cells by ingenol derivatives
-
PMID: 9856087
-
Fujiwara M, OkamotoM, Ijichi K, Tokuhisa K, Hanasaki Y, Katsuura K, et al. Upregulation of HIV-1 replication in chronically infected cells by ingenol derivatives. Arch. Virol. 1998; 143: 2003. PMID: 9856087
-
(1998)
Arch. Virol
, vol.143
, pp. 2003
-
-
Fujiwara, M.1
Okamoto, M.2
Ijichi, K.3
Tokuhisa, K.4
Hanasaki, Y.5
Katsuura, K.6
-
19
-
-
84901354407
-
Dual role of novel ingenol derivatives from Euphorbia tirucalli in HIV replication: Inhibition of de novoinfection and activation of viral LTR
-
May 14 PMID: 24827152
-
AbreuCM, Price SL, Shirk EN, Cunha RD, Pianowski LF,Clements JE, et al. Dual role of novel ingenol derivatives from Euphorbia tirucalli in HIV replication: inhibition of de novoinfection and activation of viral LTR. PLoS One. 2014 May 14; 9(5):e97257. https://doi.org/10.1371/journal.pone.0097257 PMID: 24827152
-
(2014)
PLoS One
, vol.9
, Issue.5
, pp. e97257
-
-
Abreu, C.M.1
Price, S.L.2
Shirk, E.N.3
Cunha, R.D.4
Pianowski Lfclements, J.E.5
-
20
-
-
84941290489
-
Ex vivo bioactivity and HIV-1 latency reversal by ingenoldibenzoate and panobinostat in resting CD4(+) T cells from aviremic patients
-
Oct PMID: 26169416
-
Spivak AM, Bosque A, Balch AH, Smyth D, Martins L, Planelles V. Ex VivoBioactivity and HIV-1 Latency Reversal by IngenolDibenzoate and Panobinostat in Resting CD4(+) T Cells from Aviremic Patients. Antimicrob Agents Chemother. 2015 Oct; 59(10):5984-91. https://doi.org/10.1128/AAC. 01077-15 PMID: 26169416
-
(2015)
Antimicrob Agents Chemother
, vol.59
, Issue.10
, pp. 5984-5991
-
-
Spivak, A.M.1
Bosque, A.2
Balch, A.H.3
Smyth, D.4
Martins, L.5
Planelles, V.6
-
21
-
-
84938767578
-
Synergistic Reactivation of Latent HIV Expression by Ingenol-3-Angelate, PEP005, Targeted NF-kB Signaling in Combination with JQ1 Induced p-TEFb Activation
-
Jul 30
-
Jiang G, Mendes EA, Kaiser P, Wong DP, Tang Y, Cai I, et al Synergistic Reactivation of Latent HIV Expression by Ingenol-3-Angelate, PEP005, Targeted NF-kB Signaling in Combination with JQ1 Induced p-TEFb Activation. PLoSPathog. 2015 Jul 30; 11(7):e1005066
-
(2015)
PLoSPathog
, vol.11
, Issue.7
, pp. e1005066
-
-
Jiang, G.1
Mendes, E.A.2
Kaiser, P.3
Wong, D.P.4
Tang, Y.5
Cai, I.6
-
22
-
-
85006462037
-
Reactivation of SIV reservoirs in the brain of virally suppressed macaques
-
Sep 20
-
Gama L, AbreuCM, Shirk EN, Price SL, Li M, Laird GM, et al. Reactivation of SIV reservoirs in the brain of virally suppressed macaques. AIDS. 2016 Sep 20
-
(2016)
AIDS
-
-
Gama, L.1
Abreu, C.M.2
Shirk, E.N.3
Price, S.L.4
Li, M.5
Laird, G.M.6
-
23
-
-
70449657764
-
Elucidating the elite: Mechanisms of control in HIV-1 infection
-
Dec 30 PMID: 19837464
-
OConnell KA, Bailey JR, Blankson JN. Elucidating the elite: mechanisms of control in HIV-1 infection. Trends Pharmacol Sci. 2009 Dec; 30(12):631-7. https://doi.org/10.1016/j.tips.2009.09.005 PMID: 19837464
-
(2009)
Trends Pharmacol Sci
, vol.12
, pp. 631-637
-
-
Oconnell, K.A.1
Bailey, J.R.2
Blankson, J.N.3
-
24
-
-
0036852179
-
HIV-specific CD8 + T cell proliferation is coupled toperforin expression and is maintained in nonprogressors
-
PMID: 12368910
-
Migueles SA, LaboricoAC, Shupert WL, Sabbaghian MS, Rabin R, Hallahan CW,et al. HIV-specific CD8 + T cell proliferation is coupled toperforin expression and is maintained in nonprogressors. Nat. Immunol. 2002; 3:1061-1068 https://doi.org/10.1038/ni845 PMID: 12368910
-
(2002)
Nat. Immunol
, vol.3
, pp. 1061-1068
-
-
Migueles, S.A.1
Laborico, A.C.2
Shupert, W.L.3
Sabbaghian, M.S.4
Rabin, R.5
Hallahan, C.W.6
-
25
-
-
33646686040
-
HIV nonprogressors preferentially maintain highly functional HIV-specific CD8 + T cells
-
PMID: 16467198
-
Betts MR, Nason MC, West SM, De Rosa SC, Migueles SA, Abraham J, et al. HIV nonprogressors preferentially maintain highly functional HIV-specific CD8 + T cells. Blood. 2006; 107:4781-4789 https://doi. org/10.1182/blood-2005-12-4818 PMID: 16467198
-
(2006)
Blood
, vol.107
, pp. 4781-4789
-
-
Betts, M.R.1
Nason, M.C.2
West, S.M.3
De Rosa, S.C.4
Migueles, S.A.5
Abraham, J.6
-
26
-
-
34249852256
-
Agence Nationale de Recherches sur le Sida EP36 HIV Controllers Study Group HIV controllers exhibit potent CD8 T cell capacity tosuppress HIV infection ex vivoand peculiar cytotoxic T lymphocyte activation phenotype
-
PMID: 17428922
-
Saez-Cirion A, Lacabaratz C, Lambotte O, Versmisse P, Urrutia A, Boufassa F, et al., AgenceNationale de Recherches sur le Sida EP36 HIV Controllers Study Group HIV controllers exhibit potent CD8 T cell capacity tosuppress HIV infection ex vivoand peculiar cytotoxic T lymphocyte activation phenotype. Proc. Natl. Acad. Sci. U. S. A. 2007; 104:6776-6781 https://doi.org/10.1073/pnas.0611244104 PMID: 17428922
-
(2007)
Proc. Natl. Acad. Sci. U. S. A
, vol.104
, pp. 6776-6781
-
-
Saez-Cirion, A.1
Lacabaratz, C.2
Lambotte, O.3
Versmisse, P.4
Urrutia, A.5
Boufassa, F.6
-
27
-
-
57449109484
-
Lytic granule loading of CD8 + T cells is required for HIV-infected cell elimination associated with immune control
-
PMID: 19062316
-
Migueles SA, Osborne CM, Royce C, Compton AA, Joshi RP, Weeks KA, et al. Lytic granule loading of CD8 + T cells is required for HIV-infected cell elimination associated with immune control. Immunity. 2008; 29:1009-1021. https://doi.org/10.1016/j.immuni.2008.10.010 PMID: 19062316
-
(2008)
Immunity
, vol.29
, pp. 1009-1021
-
-
Migueles, S.A.1
Osborne, C.M.2
Royce, C.3
Compton, A.A.4
Joshi, R.P.5
Weeks, K.A.6
-
28
-
-
77954080011
-
Perforin expression directly ex vivoby HIV-specific CD8 T-cells is a correlate of HIV elite control
-
Hersperger AR, Pereyra F, Nason M, Demers K, Sheth P, Shin LY, et al. Perforin expression directly ex vivoby HIV-specific CD8 T-cells is a correlate of HIV elite control. PLoSPathog. 2010; 6
-
(2010)
PLoSPathog
, vol.6
-
-
Hersperger, A.R.1
Pereyra, F.2
Nason, M.3
Demers, K.4
Sheth, P.5
Shin, L.Y.6
-
29
-
-
33646686040
-
HIV nonprogressors preferentially maintain highly functional HIV-specific CD8 + T cells
-
PMID: 16467198
-
Betts MR, Nason MC, West SM, De Rosa SC, Migueles SA, Abraham J, et al. HIV nonprogressors preferentially maintain highly functional HIV-specific CD8 + T cells. Blood. 2006; 107:4781-4789 https://doi. org/10.1182/blood-2005-12-4818 PMID: 16467198
-
(2006)
Blood
, vol.107
, pp. 4781-4789
-
-
Betts, M.R.1
Nason, M.C.2
West, S.M.3
De Rosa, S.C.4
Migueles, S.A.5
Abraham, J.6
-
30
-
-
84879481622
-
Primary CD8+ T cells from elite suppressors effectively eliminate non-productively HIV-1 infected resting and activated CD4+ T cells
-
Jul 1 PMID: 23816179
-
BuckheitRW 3rd, SilicianoRF, Blankson JN. Primary CD8+ T cells from elite suppressors effectively eliminate non-productively HIV-1 infected resting and activated CD4+ T cells. Retrovirology. 2013 Jul 1; 10:68. https://doi.org/10.1186/1742-4690-10-68 PMID: 23816179
-
(2013)
Retrovirology
, vol.10
, pp. 68
-
-
Buckheit, R.W.1
Siliciano, R.F.2
Blankson, J.N.3
-
31
-
-
78650171369
-
Differentiation therapy in poor risk myeloid malignancies: Results of a dose finding study of the combination bryostatin-1 and GM-CSF
-
PMID: 20598742
-
Smith BD, Jones RJ, ChoE, Kowalski J, Karp JE, Gore SD, et al.Differentiation therapy in poor risk myeloid malignancies: Results of a dose finding study of the combination bryostatin-1 and GM-CSF. Leukemia research. 2011; 35(1):87-94. https://doi.org/10.1016/j.leukres.2010.06.001 PMID: 20598742
-
(2011)
Leukemia Research
, vol.35
, Issue.1
, pp. 87-94
-
-
Smith, B.D.1
Jones, R.J.2
Cho, E.3
Kowalski, J.4
Karp, J.E.5
Gore, S.D.6
-
32
-
-
84863337769
-
Stimulation of HIV-1-specific cytolytic T lymphocytes facilitates elimination of latent viral reservoir after virus reactivation
-
Mar 23 PMID: 22406268
-
Shan L, Deng K, Shroff NS, Durand CM, Rabi SA, Yang HC, et al. Stimulation of HIV-1-specific cytolytic T lymphocytes facilitates elimination of latent viral reservoir after virus reactivation. Immunity. 2012 Mar 23; 36(3):491-501 https://doi.org/10.1016/j.immuni.2012.01.014 PMID: 22406268
-
(2012)
Immunity
, vol.36
, Issue.3
, pp. 491-501
-
-
Shan, L.1
Deng, K.2
Shroff, N.S.3
Durand, C.M.4
Rabi, S.A.5
Yang, H.C.6
|