Looking beyond ectopic fat amount: A SMART method to quantify epicardial adipose tissue density

European Journal of Preventive Cardiology

Volumn 24, Issue 6, 2017, Pages 657-659

  Gaborit, Bénédicte ^a,b   Dutour, Anne ^a,b  

^a AIX MARSEILLE UNIVERSITY   (France)

^b Centre Hospitalier Universitaire   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVIN A; ANGIOTENSIN; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; LOW DENSITY LIPOPROTEIN CHOLESTEROL; SECRETORY PHOSPHOLIPASE A2;

ANGIOGENESIS; AORTA ATHEROSCLEROSIS; CELL ADHESION; CELL PROLIFERATION; COMPUTER ASSISTED TOMOGRAPHY; CORONARY FLOW RESERVE; DIABETES MELLITUS; EDITORIAL; EPICARDIAL FAT; FAT MASS; HUMAN; LIPID STORAGE; PRIORITY JOURNAL; RESTENOSIS; SYSTOLIC BLOOD PRESSURE; UNSTABLE ANGINA PECTORIS; WAIST CIRCUMFERENCE; ADIPOSE TISSUE; PERICARDIUM;

ADIPOSE TISSUE; HUMANS; PERICARDIUM;

EID: 85018683358     PISSN: 20474873     EISSN: 20474881     Source Type: Journal    
DOI: 10.1177/2047487317689976     Document Type: Editorial

References (28)

1. Sacks HS and Fain JN. Human epicardial adipose tissue: A review. Am Heart J 2007; 153: 907-917.
2. Rabkin SW. Epicardial fat: properties, function and relationship to obesity. Obes Rev 2007; 8: 253-261.
3. Cherian S, Lopaschuk GD and Carvalho E. Cellular crosstalk between epicardial adipose tissue and myocardium in relation to the pathogenesis of cardiovascular disease. Am J Physiol Endocrinol Metab 2012; 303: E937-E949.
4. Rietdorf K and MacQueen H. Investigating interactions between epicardial adipose tissue and cardiac myocytes: what can we learn from different approaches? Br J Pharmacol. Epub ahead of print 24 November 2016. DOI: 10.1111/bph.13678.
5. Mazurek T. Human epicardial adipose tissue is a source of inflammatory mediators. Circulation 2003; 108: 2460-2466.
6. Sacks HS and Fain JN. Human epicardial fat: what is new and what is missing? Clin Exp Pharmacol Physiol 2011; 38: 879-887.
7. Hirata Y, Tabata M, Kurobe H, et al. Coronary atherosclerosis is associated with macrophage polarization in epicardial adipose tissue. J Am Coll Cardiol 2011; 58: 248-255.
8. Karastergiou K, Evans I, Ogston N, et al. Epicardial adipokines in obesity and coronary artery disease induce atherogenic changes in monocytes and endothelial cells. Arterioscler Thromb Vasc Biol 2010; 30: 1340-1346.
9. Venteclef N, Guglielmi V, Balse E, et al. Human epicardial adipose tissue induces fibrosis of the atrial myocardium through the secretion of adipo-fibrokines. Eur Heart J 2015; 36: 795-805a.
10. Silaghi A, Achard V, Paulmyer-Lacroix O, et al. Expression of adrenomedullin in human epicardial adipose tissue: role of coronary status. AJP Endocrinol Metab 2007; 293: E1443-E1450.
11. Sacks HS, Fain JN, Holman B, et al. Uncoupling protein-1 and related messenger ribonucleic acids in human epicardial and other adipose tissues: epicardial fat functioning as brown fat. J Clin Endocrinol Metab 2009; 94: 3611-3615.
12. Ojha S, Fainberg HP, Wilson V, et al. Gene pathway development in human epicardial adipose tissue during early life. JCI Insight 2016; 1: e87460.
13. Moreno-Santos I, Pérez-Belmonte LM, Macías-Gonzá lez M, et al. Type 2 diabetes is associated with decreased PGC1a expression in epicardial adipose tissue of patients with coronary artery disease. J Transl Med 2016; 14: 243.
14. Fitzgibbons TP and Czech MP. Epicardial and perivascular adipose tissues and their influence on cardiovascular disease: basic mechanisms and clinical associations. J Am Heart Assoc 2014; 3: e000582.
15. Mahabadi AA, Berg MH, Lehmann N, et al. Association of epicardial fat with cardiovascular risk factors and incident myocardial infarction in the general population: The Heinz Nixdorf Recall Study. J Am Coll Cardiol 2013; 61: 1388-1395.
16. Ito T, Nasu K, Terashima M, et al. The impact of epicardial fat volume on coronary plaque vulnerability: insight from optical coherence tomography analysis. Eur Heart J Cardiovasc Imaging 2012; 13: 408-415.
17. Zhou Y, Zhang H-W, Tian F, et al. Influence of increased epicardial adipose tissue volume on 1-year in-stent restenosis in patients who received coronary stent implantation. J Geriatr Cardiol JGC 2016; 13: 768-775.
18. Homsi R, Sprinkart AM, Gieseke J, et al. 3D-Dixon cardiac magnetic resonance detects an increased epicardial fat volume in hypertensive men with myocardial infarction. Eur J Radiol 2016; 85: 936-942.
19. Franssens BT, Nathoe HM, Leiner T, et al. Relation between cardiovascular disease risk factors and epicardial adipose tissue density on cardiac computed tomography in patients at high risk of cardiovascular events. Eur J Prev Cardiol 2017; 24: 660-670.
20. Rosenquist KJ, Pedley A, Massaro JM, et al. Visceral and subcutaneous fat quality and cardiometabolic risk. JACC Cardiovasc Imaging 2013; 6: 762-771.
21. Simons PC, Algra A, van de Laak MF, et al. Second manifestations of ARTerial disease (SMART) study: rationale and design. Eur J Epidemiol 1999; 15: 773-781.
22. Tanami Y, Jinzaki M, Kishi S, et al. Lack of association between epicardial fat volume and extent of coronary artery calcification, severity of coronary artery disease, or presence of myocardial perfusion abnormalities in a diverse, symptomatic patient population: results from the CORE320 multicenter study. Circ Cardiovasc Imaging 2015; 8: e002676.
23. Gaborit B, Kober F, Jacquier A, et al. Assessment of epicardial fat volume and myocardial triglyceride content in severely obese subjects: relationship to metabolic profile, cardiac function and visceral fat. Int J Obes 2005 2012; 36: 422-430.
24. Lu MT, Park J, Ghemigian K, et al. Epicardial and paracardial adipose tissue volume and attenuation -association with high-risk coronary plaque on computed tomographic angiography in the ROMICAT II trial. Atherosclerosis 2016; 251: 47-54.
25. Alvey NJ, Pedley A, Rosenquist KJ, et al. Association of fat density with subclinical atherosclerosis. J Am Heart Assoc. Epub ahead of print 28 August 2014. DOI: 10.1161/JAHA.114.000788.
26. Gaborit B, Venteclef N, Ancel P, et al. Human epicardial adipose tissue has a specific transcriptomic signature depending on its anatomical peri-atrial, peri-ventricular, or peri-coronary location. Cardiovasc Res 2015; 108: 62-73.
27. Konishi M, Sugiyama S, Sato Y, et al. Pericardial fat inflammation correlates with coronary artery disease. Atherosclerosis 2010; 213: 649-655.
28. Kusayama T, Furusho H, Kashiwagi H, et al. Inflammation of left atrial epicardial adipose tissue is associated with paroxysmal atrial fibrillation. J Cardiol 2016; 68: 406-411.