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Volumn 650, Issue , 2017, Pages 82-88

Tenuigenin down-regulates the release of nitric oxide, matrix metalloproteinase-9 and cytokines from lipopolysaccharide-stimulated microglia

Author keywords

Cytokine; Matrix metalloproteinase 9; Microglia; Nitric oxide; Tenuigenin

Indexed keywords

BETA ACTIN; GELATINASE B; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; LIPOPOLYSACCHARIDE; MESSENGER RNA; MINOCYCLINE; NEUROPROTECTIVE AGENT; NITRIC OXIDE; NITRITE; PLANT EXTRACT; TENUIGENIN; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; CYTOKINE; HERBACEOUS AGENT; MMP9 PROTEIN, RAT;

EID: 85018596368     PISSN: 03043940     EISSN: 18727972     Source Type: Journal    
DOI: 10.1016/j.neulet.2017.04.001     Document Type: Article
Times cited : (22)

References (18)
  • 1
    • 84956681780 scopus 로고    scopus 로고
    • The neuritogenic and neuroprotective potential of senegenin against Aβ-induced neurotoxicity in PC 12 cells
    • [1] Jesky, R., Chen, H., The neuritogenic and neuroprotective potential of senegenin against Aβ-induced neurotoxicity in PC 12 cells. BMC Complement Altern. Med., 16, 2016, 26.
    • (2016) BMC Complement Altern. Med. , vol.16 , pp. 26
    • Jesky, R.1    Chen, H.2
  • 2
    • 84942818239 scopus 로고    scopus 로고
    • Senegenin inhibits hypoxia/reoxygenation-induced neuronal apoptosis by upregulating RhoGDIα
    • [2] Li, X., Zhao, Y., Liu, P., Zhu, X., Chen, M., Wang, H., Lu, D., Qi, R., Senegenin inhibits hypoxia/reoxygenation-induced neuronal apoptosis by upregulating RhoGDIα. Mol. Neurobiol. 52 (2015), 1561–1571.
    • (2015) Mol. Neurobiol. , vol.52 , pp. 1561-1571
    • Li, X.1    Zhao, Y.2    Liu, P.3    Zhu, X.4    Chen, M.5    Wang, H.6    Lu, D.7    Qi, R.8
  • 3
    • 79956333078 scopus 로고    scopus 로고
    • Neuroprotective effects of tenuigenin in a SH-SY5Y cell model with 6-OHDA-induced injury
    • [3] Liang, Z., Shi, F., Wang, Y., Lu, L., Zhang, Z., Wang, X., Wang, X., Neuroprotective effects of tenuigenin in a SH-SY5Y cell model with 6-OHDA-induced injury. Neurosci. Lett. 497 (2011), 104–109.
    • (2011) Neurosci. Lett. , vol.497 , pp. 104-109
    • Liang, Z.1    Shi, F.2    Wang, Y.3    Lu, L.4    Zhang, Z.5    Wang, X.6    Wang, X.7
  • 4
    • 84983071295 scopus 로고    scopus 로고
    • How neuroinflammation contributes to neurodegeneration
    • [4] Ransohoff, R.M., How neuroinflammation contributes to neurodegeneration. Science 353 (2016), 777–783.
    • (2016) Science , vol.353 , pp. 777-783
    • Ransohoff, R.M.1
  • 5
    • 84949969049 scopus 로고    scopus 로고
    • Getting to NO alzheimer's disease: neuroprotection versus neurotoxicity mediated by nitric oxide
    • [5] Balez, R., Ooi, L., Getting to NO alzheimer's disease: neuroprotection versus neurotoxicity mediated by nitric oxide. Oxid. Med. Cell Longev. 2016 (2016), 1–8.
    • (2016) Oxid. Med. Cell Longev. , vol.2016 , pp. 1-8
    • Balez, R.1    Ooi, L.2
  • 6
    • 84922322478 scopus 로고    scopus 로고
    • On the structure and functions of gelatinase B/matrix metalloproteinase-9 in neuroinflammation
    • [6] Vandooren, J., Van Damme, J., Opdenakker, G., On the structure and functions of gelatinase B/matrix metalloproteinase-9 in neuroinflammation. Prog. Brain Res. 214 (2014), 193–206.
    • (2014) Prog. Brain Res. , vol.214 , pp. 193-206
    • Vandooren, J.1    Van Damme, J.2    Opdenakker, G.3
  • 7
    • 0022922108 scopus 로고
    • Characterization of ameboid microglia isolated from developing mammalian brain
    • [7] Giulian, D., Baker, T.J., Characterization of ameboid microglia isolated from developing mammalian brain. J. Neurosci. 6 (1986), 2163–2178.
    • (1986) J. Neurosci. , vol.6 , pp. 2163-2178
    • Giulian, D.1    Baker, T.J.2
  • 8
    • 0028345645 scopus 로고
    • Quantitative zymography: detection of pictogram quantities of gelatinases
    • [8] Kleiner, D.E., Stetler-Stevenson, W.G., Quantitative zymography: detection of pictogram quantities of gelatinases. Anal. Biochem. 218 (1994), 325–329.
    • (1994) Anal. Biochem. , vol.218 , pp. 325-329
    • Kleiner, D.E.1    Stetler-Stevenson, W.G.2
  • 10
    • 84875681148 scopus 로고    scopus 로고
    • Tenuigenin treatment improves behavioral Y-maze learning by enhancing synaptic plasticity in mice
    • [10] Huang, J.N., Wang, C.Y., Wang, X.L., Wu, B.Z., Gu, X.Y., Liu, W.X., Gong, L.W., Xiao, P., Li, C.H., Tenuigenin treatment improves behavioral Y-maze learning by enhancing synaptic plasticity in mice. Behav. Brain Res. 246 (2013), 111–115.
    • (2013) Behav. Brain Res. , vol.246 , pp. 111-115
    • Huang, J.N.1    Wang, C.Y.2    Wang, X.L.3    Wu, B.Z.4    Gu, X.Y.5    Liu, W.X.6    Gong, L.W.7    Xiao, P.8    Li, C.H.9
  • 12
    • 84863534146 scopus 로고    scopus 로고
    • Tenuigenin protects dopaminergic neurons from inflammation-mediated damage induced by the lipopolysaccharide
    • [12] Yuan, H.L., Li, B., Xu, J., Wang, Y., He, Y., Zheng, Y., Wang, X.M., Tenuigenin protects dopaminergic neurons from inflammation-mediated damage induced by the lipopolysaccharide. CNS Neurosci. Ther. 18 (2012), 584–590.
    • (2012) CNS Neurosci. Ther. , vol.18 , pp. 584-590
    • Yuan, H.L.1    Li, B.2    Xu, J.3    Wang, Y.4    He, Y.5    Zheng, Y.6    Wang, X.M.7
  • 13
    • 84956623784 scopus 로고    scopus 로고
    • Tenuigenin exhibits anti-inflammatory activity via inhibiting MAPK and NF-κB and inducing Nrf2/HO-1 signaling in macrophages
    • [13] Lv, H., Ren, W., Zheng, Y., Wang, L., Lu, G., Yi, P., Ci, X., Tenuigenin exhibits anti-inflammatory activity via inhibiting MAPK and NF-κB and inducing Nrf2/HO-1 signaling in macrophages. Food Funct. 7 (2016), 355–363.
    • (2016) Food Funct. , vol.7 , pp. 355-363
    • Lv, H.1    Ren, W.2    Zheng, Y.3    Wang, L.4    Lu, G.5    Yi, P.6    Ci, X.7
  • 14
    • 0033556024 scopus 로고    scopus 로고
    • Matrix metalloproteinase 2 (MMP2) and MMP9 are produced by kidney collecting duct principal cells but are differentially regulated by SV40 large-T arginine vasopressin, and epidermal growth factor
    • [14] Piedagnel, R., Murphy, G., Ronco, P.M., Lelongt, B., Matrix metalloproteinase 2 (MMP2) and MMP9 are produced by kidney collecting duct principal cells but are differentially regulated by SV40 large-T arginine vasopressin, and epidermal growth factor. J. Biol. Chem. 274 (1999), 1614–1620.
    • (1999) J. Biol. Chem. , vol.274 , pp. 1614-1620
    • Piedagnel, R.1    Murphy, G.2    Ronco, P.M.3    Lelongt, B.4
  • 16
    • 84935030100 scopus 로고    scopus 로고
    • Tenuigenin ameliorates acute lung injury by inhibiting NF-κB and MAPK signalling pathways
    • [16] Lv, H., Zhu, C., Liao, Y., Gao, Y., Lu, G., Zhong, W., Zheng, Y., Chen, W., Ci, X., Tenuigenin ameliorates acute lung injury by inhibiting NF-κB and MAPK signalling pathways. Respir, Physiol, Neurobiol. 216 (2015), 43–51.
    • (2015) Respir, Physiol, Neurobiol. , vol.216 , pp. 43-51
    • Lv, H.1    Zhu, C.2    Liao, Y.3    Gao, Y.4    Lu, G.5    Zhong, W.6    Zheng, Y.7    Chen, W.8    Ci, X.9
  • 17
    • 84986331398 scopus 로고    scopus 로고
    • Tenuigenin exhibits protective effects against LPS-induced acute kidney injury via inhibiting TLR4/NF-κB signaling pathway
    • [17] Fu, H., Hu, Z., Di, X., Zhang, Q., Zhou, R., Du, H., Tenuigenin exhibits protective effects against LPS-induced acute kidney injury via inhibiting TLR4/NF-κB signaling pathway. Eur. J. Pharmacol. 791 (2016), 229–234.
    • (2016) Eur. J. Pharmacol. , vol.791 , pp. 229-234
    • Fu, H.1    Hu, Z.2    Di, X.3    Zhang, Q.4    Zhou, R.5    Du, H.6
  • 18
    • 84957539993 scopus 로고    scopus 로고
    • Tenuigenin prevents IL-1β-induced inflammation in human osteoarthritis chondrocytes by suppressing PI3 K/AKT/NF-κB signaling pathway
    • [18] Wang, C., Zeng, L., Zhang, T., Liu, J., Wang, W., Tenuigenin prevents IL-1β-induced inflammation in human osteoarthritis chondrocytes by suppressing PI3 K/AKT/NF-κB signaling pathway. Inflammation 39 (2016), 807–812.
    • (2016) Inflammation , vol.39 , pp. 807-812
    • Wang, C.1    Zeng, L.2    Zhang, T.3    Liu, J.4    Wang, W.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.