Mortality, survival and incidence rates in the ITALUNG randomised lung cancer screening trial

Thorax

Volumn 72, Issue 9, 2017, Pages 825-831

  Paci, Eugenio ^a   Puliti, Donella ^a   Lopes Pegna, Andrea ^b   Carrozzi, Laura ^c   Picozzi, Giulia ^a   Falaschi, Fabio ^c   Pistelli, Francesco ^c   Aquilini, Ferruccio ^c   Ocello, Cristina ^a   Zappa, Marco ^a   Carozzi, Francesca M ^a   Mascalchi, Mario ^d   Manneschi, G ^e   Visioli, C ^e   Cordopatri, G ^e   Giusti, F ^e   Esposito, I ^e   Bianchi, R ^e   Ronchi, C ^e   Cini, S ^e   De Santis, M ^e   Baliva, F ^e   Chella, A ^e   Tavanti, L ^e   Grazzini, M ^e   Innocenti, F ^e   Natali, I ^e   Bartolucci, M ^e   Crisci, E ^e   De Francisci, A ^e   Falchini, M ^e   Gabbrielli, S ^e   Roselli, G ^e   Masi, A ^e   Battola, L ^e   De Liperi, A ^e   Spinelli, C ^e   Vannucchi, L ^e   Petruzzelli, A ^e   Gadda, D ^e   Neri, A T ^e   Niccolai, F ^e   Vaggelli, L ^e   Vella, A ^e   Maddau, C ^e   Bisanzi, S ^e   Janni, A ^e   Mussi, A ^e   Lucchi, M ^e   Comin, C ^e   Fontanini, G ^e   Tognetti, A R ^e   Iacuzio, L ^e   Caldarella, A ^e   Barchielli, A ^e   Goldoni, C A ^e   more..

^a CANCER RESEARCH AND PREVENTION INSTITUTE ISPO   (Italy)

^b CAREGGI UNIVERSITY HOSPITAL   (Italy)

^c UNIVERSITY HOSPITAL OF PISA   (Italy)

^d UNIVERSITY OF FLORENCE   (Italy)

^e NONE

Author keywords

Clinical Epidemiology; Lung Cancer

Indexed keywords

ADULT; AGED; ARTICLE; CANCER DIAGNOSIS; CANCER INCIDENCE; CANCER MORTALITY; CANCER REGISTRY; CANCER SCREENING; CANCER STAGING; CANCER SURVIVAL; CAUSE OF DEATH; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; FEMALE; FOLLOW UP; HUMAN; LUNG CANCER; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; MORTALITY RATE; OUTCOME ASSESSMENT; PRIORITY JOURNAL; QUESTIONNAIRE; RANDOMIZED CONTROLLED TRIAL; SMOKING HABIT; SURVIVAL RATE; ADVERSE EFFECTS; CLINICAL TRIAL; DIAGNOSTIC IMAGING; EARLY CANCER DIAGNOSIS; INCIDENCE; ITALY; KAPLAN MEIER METHOD; LUNG NEOPLASMS; MULTICENTER STUDY; PATHOLOGY; PROCEDURES; REGISTER; SMOKING; X-RAY COMPUTED TOMOGRAPHY;

AGED; EARLY DETECTION OF CANCER; FEMALE; FOLLOW-UP STUDIES; HUMANS; INCIDENCE; ITALY; KAPLAN-MEIER ESTIMATE; LUNG NEOPLASMS; MALE; MIDDLE AGED; NEOPLASM STAGING; REGISTRIES; SMOKING; TOMOGRAPHY, X-RAY COMPUTED;

EID: 85018491483     PISSN: 00406376     EISSN: 14683296     Source Type: Journal    
DOI: 10.1136/thoraxjnl-2016-209825     Document Type: Article

References (29)

1. Associazione Italiana Registri Tumori (AIRTUM). I numeri del cancro in Italia, 2015. http://www.registri-Tumori.it
2. AIRTUM Working Group. Italian cancer figures, report 2011: Survival of cancer patients in Italy. Epidemiol Prev 2011;35(Suppl 3):1-200.
3. Carreras G, Gorini G, Gallus S, et al. Predicting the future prevalence of cigarette smoking in Italy over the next three decades. Eur J Public Health 2012;22:699-704.
4. http://www.salute.gov.it/portale/temi/p2-4.jsp?area=prevenzione (accessed 07/06/2016).
5. National Lung Screening Trial Research TeamAberle DR, Adams AM, Berg CD, et al. Reduced lung-cancer mortality with low-dose computed tomographic screening. N Engl J Med 2011; 365: 395-409.
6. Moyer VA, U.S. Preventive Services Task Force. Screening for lung cancer: U.S. Preventive Services Task Force recommendation statement. Ann Intern Med 2014; 160:330-8.
7. Armaroli P, Villain P, Suonio E, et al. European code against cancer, 4th edition: cancer screening. Cancer Epidemiol 2015;39(Suppl 1): S139-52.
8. Lopes Pegna A, Picozzi G, Mascalchi M, et al., ITALUNG Study Research Group. Design, recruitment and baseline results of the ITALUNG trial for lung cancer screening with low-dose CT. Lung Cancer 2009;64:34-40.
9. Lopes Pegna A, Picozzi G, Falaschi F, et al., ITALUNG Study Research Group. Four-year results of low-dose CT screening and nodule management in the ITALUNG trial. J Thorac Oncol 2013;8:866-75.
10. van Iersel CA, de Koning HJ, Draisma G, et al. Risk-based selection from the general population in a screening trial: selection criteria, recruitment and power for the Dutch-Belgian randomised lung cancer multi-slice CT screening trial (NELSON). Int J Cancer 2007;120:868-74.
11. Sobin L, Gospodarowicz M, Wittekind C, eds. International Union Against Cancer (UICC). TNM Classification of Malignant Tumours. 7th edn. Hoboken, NJ: Wiley Blackwell, 2009.
12. Fritz A, Percy C, Jack A, et al, eds. International Classification of Diseases for Oncology. 3rd edn. Geneva: World Health Organization, 2000.
13. Mascalchi M, Lopes Pegna A, Carrozzi L, et al. Does UKLS strategy increase the yield of screen-detected lung cancers? A comparison with ITALUNG. Thorax 2016;71:950-1.
14. Field JK, Duffy SW, Baldwin DR, et al. UK Lung Cancer RCT Pilot Screening Trial: baseline findings from the screening arm provide evidence for the potential implementation of lung cancer screening. Thorax 2016;71:161-70.
15. Pistelli F, Aquilini F, Tavanti L, et al. Predictors of smoking cessation within a lung cancer CT screening trial. Eur Respir J 2011;38(Suppl 55):780s.
16. Caldarella A, Amunni G, Angiolini C, et al. Feasibility of evaluating quality cancer care using registry data and electronic health records: A population-based study. Int J Qual Health Care 2012;24:411-18.
17. Mangone L, Minicozzi P, Vicentini M, et al. Key factors influencing lung cancer survival in northern Italy. Cancer Epidemiol 2013;37:226-32.
18. Field JK, Smith RA, Duffy SW, et al. The Liverpool Statement 2005: priorities for the European Union/United States spiral computed tomography collaborative group. J Thorac Oncol 2006;1:497-8.
19. Field JK, van Klaveren R, Pedersen JH, et al., European Randomized Screening Trial Group. European randomized lung cancer screening trials: post NLST. J Surg Oncol 2013;108:280-6.
20. Infante M, Lutman FR, Cavuto S, et al., DANTE Study Group. Lung cancer screening with spiral CT: baseline results of the randomized DANTE trial. Lung Cancer 2008;59:355-63.
21. Infante M, Cavuto S, Lutman FR, et al., DANTE Study Group. Long-Term follow-up results of the DANTE Trial, a randomized study of lung cancer screening with spiral computed tomography. Am J Respir Crit Care Med 2015;191:1166-75.
22. Pastorino U, Rossi M, Rosato V, et al. Annual or biennial CT screening versus observation in heavy smokers: 5-year results of the MILD trial. Eur J Cancer Prev 2012;21:308-15.
23. Pedersen JH, Ashraf H, Dirksen A, et al. The Danish randomized lung cancer CT screening trial-overall design and results of the prevalence round. J Thorac Oncol 2009;4:608-14.
24. Saghir Z, Dirksen A, Ashraf H, et al. CT screening for lung cancer brings forward early disease. The randomised Danish Lung Cancer Screening Trial: status after five annual screening rounds with low-dose CT. Thorax 2012;67:296-301.
25. Infante M, Sestini S, Galeone C, et al. Lung cancer screening with low-dose spiral computed tomography: evidence from a pooled analysis of two Italian randomized trials. Eur J Cancer Prev 2016.
26. Field JK, Duffy SW, Baldwin DR, et al. The UK Lung Cancer Screening Trial: A pilot randomised controlled trial of low-dose computed tomography screening for the early detection of lung cancer. Health Technol Assess 2016;20:1-146.
27. Becker N, Motsch E, Gross ML, et al. Randomized study on early detection of lung cancer with MSCT in Germany: results of the first 3 years of follow-up after randomization. J Thorac Oncol 2015;10: 890-6.
28. Field JK, Devaraj A, Duffy SW, et al. CT screening for lung cancer: is the evidence strong enough? Lung Cancer 2016;91:29-35.
29. Yousaf-Khan U, van der Aalst C, de Jong PA, et al. Final screening round of the NELSON lung cancer screening trial: The effect of a 2.5-year screening interval. Thorax 2017;72:48-56.