Randomized study on early detection of lung cancer with MSCT in Germany: Results of the first 3 years of follow-up after randomization

Journal of Thoracic Oncology

Volumn 10, Issue 6, 2015, Pages 890-896

  Becker, N ^a   Motsch, E ^a   Gross, M L ^a   Eigentopf, A ^a   Heussel, C P ^b,c,d   Dienemann, H ^b,d   Schnabel, P A ^d,e   Eichinger, M ^b,c   Optazaite, D E ^b,c   Puderbach, M ^b,c,f   Wielputz M ^a,c   Kauczor, H U ^c   Tremper, J ^a,d   Delorme, S ^a,d  

^a GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^b UNIVERSITY OF HEIDELBERG   (Germany)

^c UNIVERSITY OF HEIDELBERG   (Germany)

^d German Center for Lung Research (DZL)   (Germany)

^e SAARLAND UNIVERSITY   (Germany)

^f Hufeland Klinikum GmbH Bad Langensalza   (Germany)

Author keywords

cancer; low dose CT; lung; randomized trial; screening

Indexed keywords

ADULT; ADVANCED CANCER; AGED; ARTICLE; CANCER DIAGNOSIS; CANCER MORTALITY; CANCER SCREENING; CONTROLLED STUDY; FEMALE; FOLLOW UP; HUMAN; LUNG CANCER; MAJOR CLINICAL STUDY; MALE; MULTIDETECTOR COMPUTED TOMOGRAPHY; PRIORITY JOURNAL; RADIATION EXPOSURE; TUMOR BIOPSY; EARLY CANCER DIAGNOSIS; GERMANY; LUNG NEOPLASMS; MASS SCREENING; MIDDLE AGED; PATHOLOGY; PROCEDURES; RANDOMIZED CONTROLLED TRIAL;

AGED; EARLY DETECTION OF CANCER; FEMALE; FOLLOW-UP STUDIES; GERMANY; HUMANS; LUNG NEOPLASMS; MALE; MASS SCREENING; MIDDLE AGED; MULTIDETECTOR COMPUTED TOMOGRAPHY;

EID: 84938225584     PISSN: 15560864     EISSN: 15561380     Source Type: Journal    
DOI: 10.1097/JTO.0000000000000530     Document Type: Article

References (16)

1. Aberle DR, Adams AM, Berg CD, Reduced lung-cancer mortality with low-dose computed tomographic screening. New Engl J Med 2011 365 395 409
2. Saghir Z, Dirksen A, Ashraf H, CT screening for lung cancer brings forward early disease. The randomised Danish Lung Cancer Screening Trial: status after five annual screening rounds with low-dose CT. Thorax 2012 67 296 301
3. Infante M, Cavuto S, Lutman FR, DANTE Study Group A randomized study of lung cancer screening with spiral computed tomography: three-year results from the DANTE trial. Am J Respir Crit Care Med 2009 180 445 453
4. Lopes Pegna A, Picozzi G, Mascalchi M, ITALUNG Study Research Group Design, recruitment and baseline results of the ITALUNG trial for lung cancer screening with low-dose CT. Lung Cancer 2009 64 34 40
5. Pastorino U, Rossi M, Rosato V, Annual or biennial CT screening versus observation in heavy smokers: 5-year results of the MILD trial. Eur J Cancer Prev 2012 21 308 315
6. Horeweg N, van Der Aalst CM, Thunnissen E, Characteristics of lung cancers detected by computer tomography screening in the randomized NELSON trial. Am J Respir Crit Care Med 2013 187 848 854
7. Baldwin DR, Duffy SW, Wald NJ, Page R, Hansell DM, Field JK., UK Lung Screen (UKLS) nodule management protocol: modelling of a single screen randomised controlled trial of low-dose CT screening for lung cancer. Thorax 2011 66 308 313
8. Field JK, van Klaveren R, Pedersen JH, European Randomized Screening Trial Group European randomized lung cancer screening trials: post NLST. J Surg Oncol 2013 108 280 286
9. Becker N, Motsch E, Gross ML, Randomized study on early detection of lung cancer with MSCT in Germany: study design and results of the first screening round. J Cancer Res Clin Oncol 2012 138 1475 1486
10. IARC Cervix Cancer Screening 2005 Lyon IARC Press, International Agency for Research on Cancer
11. Greenwald P., Kramer B.S., Weed D.L., Prorok. Screening studies. Cancer Prevention and Control 1996 New York Basel Hong Kong Marcel Dekker
12. Church TR, Black WC, Aberle DR, Results of initial low-dose computed tomographic screening for lung cancer. N Engl J Med 2013 368 1980 1991
13. Aberle DR, DeMello S, Berg CD, National Lung Screening Trial Research Team Results of the two incidence screenings in the National Lung Screening Trial. N Engl J Med 2013 369 920 931
14. Lynge E, Olsen AH, Fracheboud J, Patnick J., Reporting of performance indicators of mammography screening in Europe. Eur J Cancer Prev 2003 12 213 222
15. Hackshaw A., EUSOMA review of mammography screening. Ann Oncol 2003 14 1193 1195
16. Pastorino U, Bellomi M, Landoni C, Early lung-cancer detection with spiral CT and positron emission tomography in heavy smokers: 2-year results. Lancet 2003 362 593 597