Netting insights into fibrosis

New England Journal of Medicine

Volumn 376, Issue 15, 2017, Pages 1475-1477

  Dimmeler, Stefanie ^a,b   Zeiher, Andreas M ^b,c  

^a GOETHE UNIVERSITY   (Germany)

^b DZHK GERMAN CENTRE FOR CARDIOVASCULAR RESEARCH   (Germany)

^c UNIVERSITY HOSPITAL FRANKFURT   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

PEPTIDES AND PROTEINS; PROTEIN PADI4; UNCLASSIFIED DRUG; HYDROLASE; PROTEIN-ARGININE DEIMINASE;

ARTICLE; EXTRACELLULAR TRAP; HEART MUSCLE FIBROSIS; LUNG FIBROSIS; MOLECULAR PATHOLOGY; MYOFIBROBLAST; NONHUMAN; ANIMAL; CARDIAC MUSCLE; DEFICIENCY; DISEASE MODEL; FIBROSIS; HUMAN; MOUSE; NEUTROPHIL; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY;

ANIMALS; DISEASE MODELS, ANIMAL; EXTRACELLULAR TRAPS; FIBROSIS; HUMANS; HYDROLASES; MICE; MYOCARDIUM; MYOFIBROBLASTS; NEUTROPHILS;

EID: 85018462677     PISSN: 00284793     EISSN: 15334406     Source Type: Journal    
DOI: 10.1056/NEJMcibr1616598     Document Type: Article

References (6)

1. Leask A. Getting to the heart of the matter: new insights into cardiac fibrosis. Circ Res 2015; 116: 1269-76
2. Gourdie RG, Dimmeler S, Kohl P. Novel therapeutic strategies targeting fibroblasts and fibrosis in heart disease. Nat Rev Drug Discov 2016; 15: 620-38
3. Martinod K, Witsch T, Erpenbeck L, et al. Peptidylarginine deiminase 4 promotes age-related organ fibrosis. J Exp Med 2017; 214: 439-58
4. Duffield JS, Lupher M, Thannickal VJ, Wynn TA. Host responses in tissue repair and fibrosis. Annu Rev Pathol 2013; 8: 241-76
5. Sørensen OE, Borregaard N. Neutrophil extracellular traps - the dark side of neutrophils. J Clin Invest 2016; 126: 1612-20
6. Satoh T, Nakagawa K, Sugihara F, et al. Identification of an atypical monocyte and committed progenitor involved in fibrosis. Nature 2017; 541: 96-101