Venous thromboembolism in radiation therapy cancer patients: Findings from the RIETE registry

Critical Reviews in Oncology/Hematology

Volumn 113, Issue , 2017, Pages 83-89

  Guy, Jean Baptiste ^a   Bertoletti, Laurent ^b,c,d   Magné, Nicolas ^a   Rancoule, Chloé ^a   Mahé, Isabelle ^e   Font, Carme ^f   Sanz, Oscar ^g   Martín Antorán, José Manuel ^h   Pace, Federica ⁱ   Vela, Jerónimo Ramón ^j   Monreal, Manuel ^k  

^a Department of Radiation Oncology   (France)

^b UNIVERSITÉ JEAN MONNET   (France)

^c INSERM   (France)

^d UNIVERSITY HOSPITAL OF SAINT ETIENNE   (France)

^e HÔPITAL LOUIS MOURIER   (France)

^f HOSPITAL CLÍNIC   (Spain)

^g HOSPITAL UNIVERSITARIO DE GRAN CANARIA DR NEGRÍN   (Spain)

^h HOSPITAL RÍO CARRIÓN   (Spain)

ⁱ SAN CAMILLO FORLANINI HOSPITAL   (Italy)

^j HOSPITAL UNIVERSITARIO MIGUEL SERVET   (Spain)

^k HOSPITAL UNIVERSITARI GERMANS TRIAS I PUJOL   (Spain)

more..

Author keywords

Anticoagulant therapy; Cancer; Pulmonary embolism; Radiation therapy; Venous thromboembolism

Indexed keywords

ANTICOAGULANT AGENT; FONDAPARINUX; HEPARIN; LOW MOLECULAR WEIGHT HEPARIN;

AGED; BLEEDING; BLOOD CLOT LYSIS; CANCER CHEMOTHERAPY; CANCER PATIENT; CANCER RADIOTHERAPY; CLINICAL FEATURE; CONTROLLED STUDY; DATA BASE; DEEP VEIN THROMBOSIS; ECHOGRAPHY; FEMALE; FOLLOW UP; HORMONAL THERAPY; HUMAN; LUNG ANGIOGRAPHY; LUNG EMBOLISM; MAJOR CLINICAL STUDY; MALE; MORTALITY RATE; PHLEBOGRAPHY; POPULATION RISK; RECURRENCE RISK; REVIEW; TREATMENT DURATION; TREATMENT OUTCOME; VENOUS THROMBOEMBOLISM; ADVERSE EFFECTS; COMPLICATION; HEMORRHAGE; MIDDLE AGED; MORTALITY; NEOPLASMS; PATHOLOGY; PROSPECTIVE STUDY; PULMONARY EMBOLISM; RECURRENT DISEASE; REGISTER; VENOUS THROMBOSIS;

AGED; FEMALE; HEMORRHAGE; HUMANS; MALE; MIDDLE AGED; NEOPLASMS; PROSPECTIVE STUDIES; PULMONARY EMBOLISM; RADIOTHERAPY; RECURRENCE; REGISTRIES; VENOUS THROMBOEMBOLISM; VENOUS THROMBOSIS;

EID: 85018461291     PISSN: 10408428     EISSN: 18790461     Source Type: Journal    
DOI: 10.1016/j.critrevonc.2017.03.006     Document Type: Review

References (33)

1. Biswal, B.M., Lal, P., Rath, G.K., Mohanti, B.K., Hemostatic radiotherapy in carcinoma of the uterine cervix. Int. J. Gynaecol. Obstet. Off. Organ Int. Fed. Gynaecol. Obstet. 50 (1995), 281–285.
2. Blirando, K., Hneino, M., Martelly, I., Benderitter, M., Milliat, F., François, A., Mast cells and ionizing radiation induce a synergistic expression of inflammatory genes in endothelial cells by a mechanism involving p38(MAP kinase and (p65) NF-κB activation. Radiat. Res. 178 (2012), 556–567, 10.1667/RR3058.1.
3. Blom, J.W., Doggen, C.J.M., Osanto, S., Rosendaal, F.R., Malignancies, prothrombotic mutations, and the risk of venous thrombosis. JAMA 293 (2005), 715–722, 10.1001/jama.293.6.715.
4. Boerma, M., Kruse, J.J.C.M., van Loenen, M., Klein, H.R., Bart, C.I., Zurcher, C., Wondergem, J., Increased deposition of von Willebrand factor in the rat heart after local ionizing irradiation. Strahlenther. Onkol. Organ Dtsch. Röntgenges. Al 180 (2004), 109–116, 10.1007/s00066-004-1138-0.
5. Byrne, M., Reynolds, J.V., O'Donnell, J.S., Keogan, M., White, B., Byrne, M., Murphy, S., Maher, S.G., Pidgeon, G.P., Long-term activation of the pro-coagulant response after neoadjuvant chemoradiation and major cancer surgery. Br. J. Cancer 102 (2010), 73–79, 10.1038/sj.bjc.6605463.
6. Chargari, C., Guy, J.-B., Falk, A.T., Schouver, E.D., Trone, J.-C., Moncharmont, C., Védrine, L., Magné, N., Cardiotoxicity research in breast cancer patients: past and future. Am. J. Cardiol. 113 (2014), 1447–1448, 10.1016/j.amjcard.2014.01.421.
7. Cihoric, N., Crowe, S., Eychmüller, S., Aebersold, D.M., Ghadjar, P., Clinically significant bleeding in incurable cancer patients: effectiveness of hemostatic radiotherapy. Radiat. Oncol. Lond. Engl., 7, 2012, 132, 10.1186/1748-717X-7-132.
8. Darby, S.C., Ewertz, M., McGale, P., Bennet, A.M., Blom-Goldman, U., Brønnum, D., Correa, C., Cutter, D., Gagliardi, G., Gigante, B., Jensen, M.-B., Nisbet, A., Peto, R., Rahimi, K., Taylor, C., Hall, P., Risk of ischemic heart disease in women after radiotherapy for breast cancer. N. Engl. J. Med. 368 (2013), 987–998, 10.1056/NEJMoa1209825.
9. Farías, C.E., Giménez, J.C., Kempfer, A.C., Singer, E., Woods, A.I., Santarelli, M.T., Lazzari, M.A., Ionizing radiation increases concentration of plasma von Willebrand factor in Cebus Apella Paraguayanus monkeys. Thromb. Res. 88 (1997), 81–87.
10. Farge, D., Trujillo-Santos, J., Debourdeau, P., Bura-Riviere, A., Rodriguez-Beltrán, E.M., Nieto, J.A., Peris, M.L., Zeltser, D., Mazzolai, L., Hij, A., Monreal, M., RIETE Investigators, Fatal events in cancer patients receiving anticoagulant therapy for venous thromboembolism. Medicine (Baltimore), 94, 2015, e1235, 10.1097/MD.0000000000001235.
11. Geerts, W.H., Bergqvist, D., Pineo, G.F., Heit, J.A., Samama, C.M., Lassen, M.R., Colwell, C.W., American College of Chest Physicians, Prevention of venous thromboembolism: american college of chest physicians evidence-based clinical practice guidelines (8th edition). Chest 133 (2008), 381S–453S, 10.1378/chest.08-0656.
12. Geiger, H., Pawar, S.A., Kerschen, E.J., Nattamai, K.J., Hernandez, I., Liang, H.P.H., Fernández, J.Á., Cancelas, J.A., Ryan, M.A., Kustikova, O., Schambach, A., Fu, Q., Wang, J., Fink, L.M., Petersen, K.-U., Zhou, D., Griffin, J.H., Baum, C., Weiler, H., Hauer-Jensen, M., Pharmacological targeting of the thrombomodulin-activated protein C pathway mitigates radiation toxicity. Nat. Med. 18 (2012), 1123–1129, 10.1038/nm.2813.
13. Goldin-Lang, P., Niebergall, F., Antoniak, S., Szotowski, B., Rosenthal, P., Pels, K., Schultheiss, H.-P., Rauch, U., Ionizing radiation induces upregulation of cellular procoagulability and tissue factor expression in human peripheral blood mononuclear cells. Thromb. Res. 120 (2007), 857–864, 10.1016/j.thromres.2007.01.008.
14. Goldin-Lang, P., Pels, K., Tran, Q.-V., Szotowski, B., Wittchen, F., Antoniak, S., Willich, T., Witt, H., Hummel, M., Lenze, D., Poller, W., Schultheiss, H.-P., Rauch, U., Effect of ionizing radiation on cellular procoagulability and co-ordinated gene alterations. Haematologica 92 (2007), 1091–1098.
15. Gujral, D.M., Chahal, N., Senior, R., Harrington, K.J., Nutting, C.M., Radiation-induced carotid artery atherosclerosis. Radiother. Oncol. J. Eur. Soc. Ther. Radiol. Oncol. 110 (2014), 31–38, 10.1016/j.radonc.2013.08.009.
16. Guy, J.-B., Falk, A.T., Chargari, C., Bertoletti, L., Magné, N., Thromboembolic events following brachytherapy: case reports. J. Contemp. Brachytherapy 7 (2015), 76–78, 10.5114/jcb.2015.48580.
17. Halle, M., Ekström, M., Farnebo, F., Tornvall, P., Endothelial activation with prothrombotic response in irradiated microvascular recipient veins. J. Plast. Reconstr. Aesthet. Surg. JPRAS 63 (2010), 1910–1916, 10.1016/j.bjps.2009.12.001.
18. Hauer-Jensen, M., Fink, L.M., Wang, J., Radiation injury and the protein C pathway. Crit. Care Med. 32 (2004), S325–330.
19. Heit, J.A., Silverstein, M.D., Mohr, D.N., Petterson, T.M., O'Fallon, W.M., Melton, L.J., Risk factors for deep vein thrombosis and pulmonary embolism: a population-based case-control study. Arch. Intern. Med. 160 (2000), 809–815.
20. Horsted, F., West, J., Grainge, M.J., Risk of venous thromboembolism in patients with cancer: a systematic review and meta-analysis. PLoS Med., 9, 2012, e1001275, 10.1371/journal.pmed.1001275.
21. Khorana, A.A., Connolly, G.C., Assessing risk of venous thromboembolism in the patient with cancer. J. Clin. Oncol. Off. J. Am. Soc. Clin. Oncol. 27 (2009), 4839–4847, 10.1200/JCO.2009.22.3271.
22. Khorana, A.A., Francis, C.W., Culakova, E., Kuderer, N.M., Lyman, G.H., Frequency, risk factors, and trends for venous thromboembolism among hospitalized cancer patients. Cancer 110 (2007), 2339–2346, 10.1002/cncr.23062.
23. Krigsfeld, G.S., Savage, A.R., Sanzari, J.K., Wroe, A.J., Gridley, D.S., Kennedy, A.R., Mechanism of hypocoagulability in proton-irradiated ferrets. Int. J. Radiat. Biol. 89 (2013), 823–831, 10.3109/09553002.2013.802394.
24. Lecumberri, R., Alfonso, A., Jiménez, D., Fernández Capitán, C., Prandoni, P., Wells, P.S., Vidal, G., Barillari, G., Monreal, M., RIETE investigators, Dynamics of case-fatalilty rates of recurrent thromboembolism and major bleeding in patients treated for venous thromboembolism. Thromb. Haemost. 110 (2013), 834–843, 10.1160/th13-02-0132.
25. Muñoz-Torrero, J.F.S., Bounameaux, H., Pedrajas, J.M., Lorenzo, A., Rubio, S., Kearon, C., Hernández, L., Monreal, M., Effects of age on the risk of dying from pulmonary embolism or bleeding during treatment of deep vein thrombosis. J. Vasc. Surg. 54 (2011), 26S–32S, 10.1016/j.jvs.2011.05.114.
26. Muriel, A., Jiménez, D., Aujesky, D., Bertoletti, L., Decousus, H., Laporte, S., Mismetti, P., Muñoz, F.J., Yusen, R., Monreal, M., RIETE Investigators, Survival effects of inferior vena cava filter in patients with acute symptomatic venous thromboembolism and a significant bleeding risk. J. Am. Coll. Cardiol. 63 (2014), 1675–1683, 10.1016/j.jacc.2014.01.058.
27. Nieto, J.A., Solano, R., Ruiz-Ribó, M.D., Ruiz-Gimenez, N., Prandoni, P., Kearon, C., Monreal, M., Riete Investigators, Fatal bleeding in patients receiving anticoagulant therapy for venous thromboembolism: findings from the RIETE registry. J. Thromb. Haemost. 8 (2010), 1216–1222, 10.1111/j.1538-7836.2010.03852.x.
28. Prandoni, P., Falanga, A., Piccioli, A., Cancer and venous thromboembolism. Lancet Oncol. 6 (2005), 401–410, 10.1016/S1470-2045(05)70207-2.
29. Ross, C.C., MacLeod, S.L., Plaxco, J.R., Froude, J.W., Fink, L.M., Wang, J., Stites, W.E., Hauer-Jensen, M., Inactivation of thrombomodulin by ionizing radiation in a cell-free system: possible implications for radiation responses in vascular endothelium. Radiat. Res. 169 (2008), 408–416, 10.1667/RR1148.1.
30. Schultz-Hector, S., Trott, K.-R., Radiation-induced cardiovascular diseases: is the epidemiologic evidence compatible with the radiobiologic data? Int. J. Radiat. Oncol. Biol. Phys. 67 (2007), 10–18, 10.1016/j.ijrobp.2006.08.071.
31. Seng, S., Liu, Z., Chiu, S.K., Proverbs-Singh, T., Sonpavde, G., Choueiri, T.K., Tsao, C.-K., Yu, M., Hahn, N.M., Oh, W.K., Galsky, M.D., Risk of venous thromboembolism in patients with cancer treated with Cisplatin: a systematic review and meta-analysis. J. Clin. Oncol. Off. J. Am. Soc. Clin. Oncol. 30 (2012), 4416–4426, 10.1200/JCO.2012.42.4358.
32. Stupp, R., Mason, W.P., van den Bent, M.J., Weller, M., Fisher, B., Taphoorn, M.J.B., Belanger, K., Brandes, A.A., Marosi, C., Bogdahn, U., Curschmann, J., Janzer, R.C., Ludwin, S.K., Gorlia, T., Allgeier, A., Lacombe, D., Cairncross, J.G., Eisenhauer, E., Mirimanoff, R.O., European Organisation for Research and Treatment of Cancer Brain Tumor, Radiotherapy Groups, National Cancer Institute of Canada Clinical Trials Group, Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N. Engl. J. Med. 352 (2005), 987–996, 10.1056/NEJMoa043330.
33. Verheij, M., Dewit, L.G., Boomgaard, M.N., Brinkman, H.J., van Mourik, J.A., Ionizing radiation enhances platelet adhesion to the extracellular matrix of human endothelial cells by an increase in the release of von Willebrand factor. Radiat. Res. 137 (1994), 202–207.