Graft-derived cell-free DNA, a noninvasive early rejection and graft damage marker in liver transplantation: A prospective, observational, multicenter cohort study

PLoS Medicine

Volumn 14, Issue 4, 2017, Pages

  Schütz, Ekkehard ^a   Fischer, Anna ^b   Beck, Julia ^a   Harden, Markus ^b   Koch, Martina ^c   Wuensch, Tilo ^d   Stockmann, Martin ^d   Nashan, Björn ^c   Kollmar, Otto ^b   Matthaei, Johannes ^b   Kanzow, Philipp ^b   Walson, Philip D ^b   Brockmöller, Jürgen ^b   Oellerich, Michael ^b  

^a Chronix Biomedical   (Germany)

^b UNIVERSITY MEDICAL CENTER GÖTTINGEN   (Germany)

^c UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^d CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AZATHIOPRINE; BASILIXIMAB; CORTICOSTEROID; CYCLOSPORIN; EVEROLIMUS; MYCOPHENOLATE MOFETIL; STEROID; TACROLIMUS; THYMOCYTE ANTIBODY; BIOLOGICAL MARKER; DNA;

ACUTE LIVER FAILURE; ADULT; ALANINE AMINOTRANSFERASE BLOOD LEVEL; APOPTOSIS; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BILIRUBIN BLOOD LEVEL; BIOPSY; CELL FREE SYSTEM; CLINICAL EVALUATION; COHORT ANALYSIS; CONTROLLED STUDY; FEMALE; GAMMA GLUTAMYL TRANSFERASE BLOOD LEVEL; GRAFT REJECTION; HEMOCHROMATOSIS; HUMAN; HUMAN TISSUE; IMMUNOSUPPRESSIVE TREATMENT; LEUKOCYTOSIS; LEUKOPENIA; LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY; LIVER CIRRHOSIS; LIVER FUNCTION TEST; LIVER TRANSPLANTATION; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; MODEL FOR END STAGE LIVER DISEASE SCORE; OBSERVATIONAL STUDY; POLYMERASE CHAIN REACTION; PROSPECTIVE STUDY; PROTHROMBIN TIME; QUANTITATIVE ANALYSIS; RECEIVER OPERATING CHARACTERISTIC; REPERFUSION INJURY; SENSITIVITY AND SPECIFICITY; AGED; AREA UNDER THE CURVE; BLOOD; CHIMERA; CLINICAL TRIAL; GERMANY; HEPACIVIRUS; LEUKOCYTE; METABOLISM; MULTICENTER STUDY; STATISTICAL MODEL;

ADULT; AGED; AREA UNDER CURVE; BIOMARKERS; CHIMERISM; DNA; FEMALE; GERMANY; GRAFT REJECTION; HEPACIVIRUS; HUMANS; LEUKOCYTES; LIVER FUNCTION TESTS; LIVER TRANSPLANTATION; LOGISTIC MODELS; MALE; MIDDLE AGED; PROSPECTIVE STUDIES; ROC CURVE;

EID: 85018287122     PISSN: 15491277     EISSN: 15491676     Source Type: Journal    
DOI: 10.1371/journal.pmed.1002286     Document Type: Article

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