Graft-derived cell-free DNA as an early organ integrity biomarker after transplantation of a marginal HELLP syndrome donor liver

Transplantation

Volumn 98, Issue 5, 2014, Pages

  Kanzow, Philipp ^a   Kollmar, Otto ^a   Schütz, Ekkehard ^b   Oellerich, Michael ^a   Schmitz, Jessica ^b   Beck, Julia ^b   Walson, Philip D ^a   Slotta, Jan E ^a  

^a UNIVERSITY MEDICAL CENTER GÖTTINGEN   (Germany)

^b Chronix Biomedical   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; BASILIXIMAB; DNA; EVEROLIMUS; GRAFT DERIVED CELL FREE DNA; METHYLPREDNISOLONE; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; TACROLIMUS; UNCLASSIFIED DRUG; BIOLOGICAL MARKER;

ACUTE GRAFT REJECTION; ADULT; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANAMNESIS; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BACTERIAL INFECTION; CASE REPORT; CYTOMEGALOVIRUS INFECTION; DNA DETERMINATION; DNA MARKER; DRUG SUBSTITUTION; DRUG TOLERABILITY; DRUG WITHDRAWAL; END STAGE LIVER DISEASE; GRAFT SURVIVAL; HELLP SYNDROME; HEMODIALYSIS; HEPATORENAL SYNDROME; HISTOLOGY; HUMAN; HUMAN TISSUE; IMMUNOSUPPRESSIVE TREATMENT; KIDNEY DYSFUNCTION; LETTER; LIVER CIRRHOSIS; LIVER GRAFT; LIVER HEMATOMA; LIVER TRANSPLANTATION; MIDDLE AGED; ORGAN DONOR; POSTOPERATIVE INFECTION; PREOPERATIVE TREATMENT; PRIORITY JOURNAL; RIB FRACTURE; SKULL FRACTURE; SUBDURAL HEMATOMA; SURGICAL TECHNIQUE; THROMBOCYTE COUNT; BLOOD; CELL FREE SYSTEM; DONOR; FEMALE; GRAFT REJECTION; PREGNANCY;

BIOLOGICAL MARKERS; CELL-FREE SYSTEM; DNA; FEMALE; GRAFT REJECTION; HELLP SYNDROME; HUMANS; LIVER TRANSPLANTATION; MIDDLE AGED; PREGNANCY; TISSUE DONORS;

EID: 84907401077     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/TP.0000000000000303     Document Type: Letter

References (4)

1. Lo YM. Transplantation monitoring by plasma DNA sequencing. Clin Chem 2011; 57: 941.
2. Beck J, Bierau S, Balzer S, et al. Digital droplet PCR for rapid quantification of donor DNA in the circulation of transplant recipients as a potential universal biomarker of graft injury. Clin Chem 2013; 59: 1732.
3. Rodr?́guez-Perálvarez M, Germani G, Papastergiou V, et al. Early tacrolimus exposure after liver transplantation: Relationship with moderate/severe acute rejection and long-term outcome. J Hepatol 2013; 58: 262.
4. Oellerich M, Schütz E, Kanzow P, et al. Use of graft-derived cell-free DNA as an organ integrity biomarker to reexamine effective tacrolimus trough concentrations after liver transplantation. Ther Drug Monit 2014; 36: 136.