Hepatitis E and blood donation safety in selected European countries: A shift to screening?

Eurosurveillance

Volumn 22, Issue 16, 2017, Pages

  Domanović, Dragoslav ^a   Tedder, R ^b   Blumel, J ^c   Zaaijer, H ^d   Gallian, P ^e   Niederhauser, C ^f   Sauleda Oliveras, S ^g   O'Riordan J ^h   Boland, F ^h   Harritshoj, L ⁱ   Nascimento, M S J ^j   Ciccaglione, A R ^k   Politis, C ^l   Adlhoch, C ^a   Flan, B ^m   Oualikene Gonin, W ⁿ   Rautmann, G ^o   Strengers, P ^p   Hewitt, P ^b  

^a EUROPEAN CENTRE FOR DISEASE PREVENTION AND CONTROL ECDC   (Sweden)

^b NHS BLOOD AND TRANSPLANT   (United Kingdom)

^c PAUL EHRLICH INSTITUT   (Germany)

^d ACADEMIC MEDICAL CENTER   (Netherlands)

^e ETABLISSEMENT FRANÇAIS DU SANG   (France)

^f Blood Transfusion Service SRC Ltd   (Switzerland)

^g BANC DE SANG I TEIXITS   (Spain)

^h IRISH BLOOD TRANSFUSION SERVICE   (Ireland)

ⁱ University of Copenhagen   (Denmark)

^j UNIVERSITY OF PORTO   (Portugal)

^k Superior Institute of National Health   (Italy)

^l SKAE Hellenic Coordinating Haemovigilance Centre   (Greece)

^m Immunology Therapeutic Unit   (France)

ⁿ Agence Nationale de Sécurité du Médicament and des Produits de Santé   (France)

^o European Directorate for the Quality of Medicines and HealthCare   (France)

^p International Plasma Fractionation Association   (Netherlands)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; BLOOD DONOR; BLOOD TRANSFUSION; DENMARK; ENZYME LINKED IMMUNOSORBENT ASSAY; FRACTIONATION; FRANCE; GENOTYPE; GERMANY; GREECE; HEPATITIS E; HUMAN; IRELAND; ITALY; LIVER INJURY; POLYMERASE CHAIN REACTION; PORTUGAL; SEROPREVALENCE; SPAIN; SWITZERLAND; UNITED KINGDOM; VIREMIA; ADVERSE EFFECTS; BLOOD; BLOOD SAFETY; EUROPE; GENETICS; HEPATITIS E VIRUS; ISOLATION AND PURIFICATION; MASS SCREENING; SEROEPIDEMIOLOGY; TRANSMISSION;

VIRUS RNA;

BLOOD DONORS; BLOOD SAFETY; BLOOD TRANSFUSION; EUROPE; HEPATITIS E; HEPATITIS E VIRUS; HUMANS; MASS SCREENING; RNA, VIRAL; SEROEPIDEMIOLOGIC STUDIES;

EID: 85018261916     PISSN: 1025496X     EISSN: 15607917     Source Type: Journal    
DOI: 10.2807/1560-7917.ES.2017.22.16.30514     Document Type: Article

References (53)

1. Barnaud E, Rogée S, Garry P, Rose N, Pavio N. Thermal inactivation of infectious hepatitis E virus in experimentally contaminated food. Appl Environ Microbiol. 2012;78(15):5153-9.DOI:10.1128/AEM.00436-12PMID: 22610436
2. Perez-Gracia MT, Garcia M, Suay B, Mateos-Lindemann ML. Current Knowledge on Hepatitis E. J Clin Transl Hepatol. 2015;3(2):117-26.
3. Schlosser B, Stein A, Neuhaus R, Pahl S, Ramez B, Krüger DH, et al. Liver transplant from a donor with occult HEV infection induced chronic hepatitis and cirrhosis in the recipient. J Hepatol. 2012;56(2):500-2.DOI:10.1016/j.jhep.2011.06.021PMID: 21798217
4. Nelson KE, Kmush B, Labrique AB. The epidemiology of hepatitis E virus infections in developed countries and among immunocompromised patients. Expert Rev Anti Infect Ther. 2011;9(12):1133-48.DOI:10.1586/eri.11.138PMID: 22114964
5. Adlhoch C, Avellon A, Baylis SA, Ciccaglione AR, Couturier E, de Sousa R, et al. Hepatitis E virus: Assessment of the epidemiological situation in humans in Europe, 2014/15. J Clin Virol. 2016;82:9-16.DOI:10.1016/j.jcv.2016.06.010PMID: 27393938
6. Kamar N, Dalton HR, Abravanel F, Izopet J. Hepatitis E virus infection. Clin Microbiol Rev. 2014;27(1):116-38.DOI:10.1128/CMR.00057-13PMID: 24396139
7. Hogema BM, Molier M, Sjerps M, de Waal M, van Swieten P, van de Laar T, et al. Incidence and duration of hepatitis E virus infection in Dutch blood donors. Transfusion. 2016;56(3):722-8.DOI:10.1111/trf.13402PMID: 26559806
8. Hewitt PE, Ijaz S, Brailsford SR, Brett R, Dicks S, Haywood B, et al. Hepatitis E virus in blood components: a prevalence and transmission study in southeast England. Lancet. 2014;384(9956):1766-73.DOI:10.1016/S0140-6736(14)61034-5PMID: 25078306
9. Baylis SA, Koc O, Nick S, Blümel J. Widespread distribution of hepatitis E virus in plasma fractionation pools. Vox Sang. 2012;102(2):182-3.DOI:10.1111/j.1423-0410.2011.01527.xPMID: 21806631
10. European Medicines Agency (EMA). Reflection paper on viral safety of plasma-derived medicinal products with respect to hepatitis E virus. London: EMA; 23 Jun 2016. Available from: http://www.ema.europa.eu/docs/en_GB/document_library/Scientific_guideline/2016/06/WC500209354.pdf
11. Tedder RS, Ijaz S, Kitchen A, Ushiro-Lumb I, Tettmar KI, Hewitt P, et al. Hepatitis E risks: pigs or blood-that is the question. Transfusion. 2017;57(2):267-72.DOI:10.1111/trf.13976PMID: 28194857
12. Dalton HR, Kamar N. Treatment of hepatitis E virus. Curr Opin Infect Dis. 2016;29(6):639-44.DOI:10.1097/QCO.0000000000000316PMID: 27607911
13. The European Directorate for the Quality of Medicines and HealthCare (EDQM). European Pharmacopoeia 8th edition; Strasbourg: Council of Europe; 2016.
14. Breum SO, Hjulsager CK, de Deus N, Segalés J, Larsen LE. Hepatitis E virus is highly prevalent in the Danish pig population. Vet Microbiol. 2010;146(1-2):144-9.DOI:10.1016/j.vetmic.2010.05.002PMID: 20554125
15. Holm DK, Moessner BK, Engle RE, Zaaijer HL, Georgsen J, Purcell RH, et al. Declining prevalence of hepatitis E antibodies among Danish blood donors. Transfusion. 2015;55(7):1662-7.DOI:10.1111/trf.13028PMID: 25819381
16. Harritshøj LH, Holm DK, Saekmose SG, Jensen BA, Hogema BM, Fischer TK, et al. Low transfusion transmission of hepatitis E among 25,637 single-donation, nucleic acid-tested blood donors. Transfusion. 2016;56(9):2225-32.DOI:10.1111/trf.13700PMID: 27385646
17. The Danish Society of Clinical Immunology. Udvalg vedrørende transfusionsoverførte infektioner, 2015. [Committee for transfusion-transmitted infections, 2015]. Danish. [Accessed 1 Apr 2017]. Available from: http://dski.dk/files/%C3%85rsberetning-for-smitteudvalget-2015.pdf
18. Gallian P, Lhomme S, Piquet Y, Sauné K, Abravanel F, Assal A, et al. Hepatitis E virus infections in blood donors, France. Emerg Infect Dis. 2014;20(11):1914-7.DOI:10.3201/eid2011.140516PMID: 25340881
19. Mansuy JM, Gallian P, Dimeglio C, Saune K, Arnaud C, Pelletier B, et al. A nationwide survey of hepatitis E viral infection in French blood donors. Hepatology. 2016;63(4):1145-54.DOI:10.1002/hep.28436PMID: 27008201
20. Hauser L, Roque-Afonso AM, Beylouné A, Simonet M, Deau Fischer B, Burin des Roziers N, et al. Hepatitis E transmission by transfusion of Intercept blood system-treated plasma. Blood. 2014;123(5):796-7.DOI:10.1182/blood-2013-09-524348PMID: 24482503
21. Féray C, Pawlotsky JM, Roque-Afonso AM, Samuel D, Dhumeaux D. Should we screen blood products for hepatitis E virus RNA? Lancet. 2014;383(9913): 218.DOI:10.1016/S0140-6736(14)60072-6PMID: 24439737
22. Robert Koch Institute (RKI). Hepatitis E. Berlin: RKI. [Accessed Oct 2016]. German. Available from: http://www.rki.de/DE/Content/InfAZ/H/HepatitisE/HepatitisE.html;jsessionid=5F3CF80856DD62113C928C009B4F0E88.2_cid381?cms_box=1&cms_current=Hepatitis+E&cms_lv2=2398522.
23. Baylis SA, Gärtner T, Nick S, Ovemyr J, Blümel J. Occurrence of hepatitis E virus RNA in plasma donations from Sweden, Germany and the United States.Vox Sang. 2012;103(1):89-90.DOI:10.1111/j.1423-0410.2011.01583.xPMID: 22220775
24. Vollmer T, Diekmann J, Johne R, Eberhardt M, Knabbe C, Dreier J. Novel approach for detection of hepatitis E virus infection in German blood donors. J Clin Microbiol. 2012;50(8):2708-13.DOI:10.1128/JCM.01119-12PMID: 22675127
25. Müller B, Koch HLP. PCR-Screening of blood donations for hepatitis E with the cobas HEV test performed on the new Roche cobas 8800 platform in minipools of 6. Transfus Med Hemother. 2015;42(suppl 1):1-64.
26. Paul-Ehrlich-Institut (PEI). Hämovigilanz-Bericht. [Hemovigilance report]. Langen: PEI. [Accessed Oct 2016]. German. Available from: http://www.pei.de/DE/arzneimittelsicherheit-vigilanz/haemovigilanz/haemovigilanzberichte/haemovigilanzberichte-node.html.
27. Bettinger D, Schorb E, Huzly D, Panning M, Schmitt-Graeff A, Kurz P, et al. Chronic hepatitis E virus infection following allogeneic hematopoietic stem cell transplantation: an important differential diagnosis for graft versus host disease. Ann Hematol. 2015;94(2):359-60.DOI:10.1007/s00277-014-2163-4PMID: 25015055
28. Pauli G, Aepfelbacher M, Bauerfeind U, Blümel J, Burger R, Gärtner B, et al. Hepatitis E Virus. Transfus Med Hemother. 2015;42(4):247-65.DOI:10.1159/000431191PMID: 26557817
29. Zervou EZ, Politis CP, Hassapopoulou EH, Vini MV, Parara MP, Kavallierou LK, et al. Prevalence of hepatitis e virus (HEV) infection in blood donors and multi-transfused patients in Greece. Vox Sang. 2015;109:242-3.
30. O’Riordan J, Boland F, Williams P, Donnellan J, Hogema BM, Ijaz S, et al. Hepatitis E virus infection in the Irish blood donor population. Transfusion. 2016;56(11):2868-76.DOI:10.1111/trf.13757PMID: 27522065
31. Stroffolini T, Menchinelli M, Dambruoso V, Menniti Ippolito F, Costantino A, Rapicetta M, et al. Prevalence of hepatitis E in a central Italian town at high endemicity for hepatitis C virus. Ital J Gastroenterol. 1996;28(9):523-5.PMID: 9131399
32. Rapicetta M, Kondili LA, Pretolani S, Stroffolini T, Chionne P, Villano U, et al. Seroprevalence and anti-HEV persistence in the general population of the Republic of San Marino. J Med Virol. 1999;58(1):49-53.DOI:10.1002/(SICI)1096-9071(199905)58:1<49::AID-JMV7>3.0.CO;2-CPMID: 10223545
33. Gessoni G, Manoni F. Hepatitis E virus infection in north-east Italy: serological study in the open population and groups at risk. J Viral Hepat. 1996;3(4):197-202.DOI:10.1111/j.1365-2893.1996.tb00095.xPMID: 8871881
34. Vulcano A, Angelucci M, Candelori E, Martini V, Patti AM, Mancini C, et al. HEV prevalence in the general population and among workers at zoonotic risk in Latium Region. Ann Ig. 2007;19(3):181-6.PMID: 17658105
35. Pavia M, Iiritano E, Veratti MA, Angelillo IF. Prevalence of hepatitis E antibodies in healthy persons in southern Italy. Infection. 1998;26(1):32-5.DOI:10.1007/BF02768749PMID: 9505177
36. De Donno A, Chironna M, Craca R, Paiano A, Zizza A, Guido M, et al. [Anti-HEV seroprevalence in the area of Lecce]. Ann Ig. 2003;15(3):199-205.PMID: 12910873
37. Scotto G, Martinelli D, Centra M, Querques M, Vittorio F, Delli Carri P, et al. Epidemiological and clinical features of HEV infection: a survey in the district of Foggia (Apulia, Southern Italy). Epidemiol Infect. 2014;142(2):287-94.DOI:10.1017/S0950268813001167PMID: 23673019
38. Epicentro. Il portale dell’epidemiologia per la sanità pubblica. Epatite virale. Aspetti epidemiologici in Italia. [Viral hepatitis. Epidemiological aspects in Italy]. Rome: Istituto superiore di sanità; 2015. Italian. Available from: http://www.Epicentro.Iss.It/problemi/epatite/epidemiologiaitalia.Asp
39. Lucarelli C, Spada E, Taliani G, Chionne P, Madonna E, Marcantonio C, et al. High prevalence of anti-hepatitis E virus antibodies among blood donors in central Italy, February to March 2014. Euro Surveill. 2016;21(30):30299.DOI:10.2807/1560-7917.ES.2016.21.30.30299PMID: 27494608
40. Rijksinstituut voor Volksgezondheid en Milieu (RIVM). Signaal 2854: ‘Hepatitis E-virus-RNA in diverse varkensleverproducten’, Signaleringsoverleg 23 juni 2016 (week 25). Alert 2854: ‘Hepatitis E virus-RNA in various pig liver products’, Alert discussion, 23 Jun 2016 (Week 25). Bilthoven: RIVM. Dutch. [Accessed April 2017]. Available from: http://rivm-lci.m13.mailplus.nl/genericservice/code/servlet/React?encId=9vRn24CiVmfDuRp&actId=507413&command=openhtml
41. HEPeCONTROL. Hepatitis E Virus Epidemiology, Safety and Control 2015 [cited 2017]. Available from: http://hepecontroleng.weebly.com/.
42. Mesquita JR, Myrmel M, Stene-Johansen K, Øverbø J, Nascimento MSJ. A Public Health initiative on hepatitis E virus epidemiology, safety and control in Portugal--study protocol. BMC Infect Dis. 2016;16(1):17.DOI:10.1186/s12879-016-1341-5PMID: 26774897
43. Riveiro-Barciela M, Sauleda S, Quer J, Salvador F, Gregori J, Pirón M, et al. Red blood cell transfusion-transmitted acute hepatitis E in an immunocompetent subject in Europe: a case report. Transfusion. 2017;57(2):244-7.DOI:10.1111/trf.13876PMID: 27785789
44. Schnegg A, Bürgisser P, André C, Kenfak-Foguena A, Canellini G, Moradpour D, et al. An analysis of the benefit of using HEV genotype 3 antigens in detecting anti-HEV IgG in a European population. PLoS One. 2013;8(5):e62980.DOI:10.1371/journal.pone.0062980PMID: 23667554
45. Gottschalk J, Hardegger K, Darnuzer R, Frey BM. Seroprevalence of Hepatitis E virus in Swiss blood donors originating from the canton of Zürich. Interlaken: SGM Jahrestagung; 2013. [Accessed April 2017]. Available from: http://www.blutspendezurich.ch/Media/File/Archiv%20div.%20Daten/HEV%20SGM%202013%20Kompatibilit%C3%A4tsmodus.pdf
46. Niederhauser C, Widmer N, Hotz M, Gowland P. Seroprevalence of Hepatitis E virus (HEV) in the Swiss blood donors: Basis for future strategy for preventing HEV transmission to at risk individuals. Vox Sang. 2016; 111 (suppl 1):305 (P240).
47. Advisory Committee on Safety of Blood, Tissues, and Organs. Minutes of the Extraordinary Meeting 7th July 2015. London; 2015. Available from: https://app.box.com/s/m6or0zdspah90u6kg3r9/1/4217161119/34764863333/1
48. Expert advisory committee on the Safety of Blood, Tissues and Organs (SaBTO). Recommendations from the expert advisory committee on the Safety of Blood, Tissues and Organs, on measures to protect patients from acquiring hepatitis E virus via transfusion and transplantation. London: SaBTO; 1 Nov 2016. Available from: https://app.box.com/s/m6or0zdspah90u6kg3r9/1/14460576146/113700100341/1
49. Berto A, Backer JA, Mesquita JR, Nascimento MS, Banks M, Martelli F, et al. Prevalence and transmission of hepatitis E virus in domestic swine populations in different European countries. BMC Res Notes. 2012;5(1):190.DOI:10.1186/1756-0500-5-190PMID: 22534364
50. Agriculture and Horticulture Development Board (AHDB). EU pig meat consumption rises in 2015. Warwickshire: AHDB; [Accessed Sep2016]. Available from: http://pork.ahdb.org.uk/prices-stats/news/2016/march/eu-pig-meat-consumption-rises-in-2015/
51. Passweg JR, Baldomero H, Bader P, Bonini C, Cesaro S, Dreger P, et al. Hematopoietic stem cell transplantation in Europe 2014: more than 40 000 transplants annually. Bone Marrow Transplant. 2016;51(6):786-92.DOI:10.1038/bmt.2016.20PMID: 26901709
52. European Directorate for the Quality of Medecines and Healthcare (EDQM). Newsletter transplant 2015. Strasbourg: Council of Europe; 2015. Available from: https://www.edqm.eu/sites/default/files/newsletter_transplant_volume_21_september_2016.pdf
53. Sauleda S, Ong E, Bes M, Janssen A, Cory R, Babizki M, et al. Seroprevalence of hepatitis E virus (HEV) and detection of HEV RNA with a transcription-mediated amplification assay in blood donors from Catalonia (Spain). Transfusion. 2015;55(5):972-9.DOI:10.1111/trf.12929PMID: 25403913