Increased Stiffness Is the Major Early Abnormality in a Pig Model of Severe Aortic Stenosis and Predisposes to Congestive Heart Failure in the Absence of Systolic Dysfunction

Journal of the American Heart Association

Volumn 4, Issue 5, 2015, Pages

  Ishikawa, Kiyotake ^a   Aguero, Jaume ^a   Oh, Jae Gyun ^a   Hammoudi, Nadjib ^a   A Fish, Lauren ^a   Leonardson, Lauren ^a   Picatoste, Belén ^a   Santos Gallego, Carlos G ^a   M Fish, Kenneth ^a   Hajjar, Roger J ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

diastolic dysfunction; fibrosis; hypertrophy; stiffness; systolic dysfunction

Indexed keywords

ADENOSINE TRIPHOSPHATASE (CALCIUM);

ANIMAL; AORTA VALVE STENOSIS; ARTERIAL STIFFNESS; CAUSALITY; COMPLICATION; DIAGNOSTIC IMAGING; DISEASE MODEL; ECHOCARDIOGRAPHY; ENZYMOLOGY; HEART ATRIUM; HEART FAILURE; HEART LEFT VENTRICLE FUNCTION; HEART RATE; HEART STROKE VOLUME; HEART VENTRICLE; HYPERTROPHY; METABOLISM; PATHOLOGY; PHYSIOLOGY; PIG; SARCOPLASMIC RETICULUM; SYSTOLE;

ANIMALS; AORTIC VALVE STENOSIS; CALCIUM-TRANSPORTING ATPASES; CAUSALITY; DISEASE MODELS, ANIMAL; ECHOCARDIOGRAPHY; HEART ATRIA; HEART FAILURE; HEART RATE; HEART VENTRICLES; HYPERTROPHY; SARCOPLASMIC RETICULUM; STROKE VOLUME; SWINE; SYSTOLE; VASCULAR STIFFNESS; VENTRICULAR FUNCTION, LEFT;

EID: 85018217795     PISSN: None     EISSN: 20479980     Source Type: Journal    
DOI: 10.1161/JAHA.115.001925     Document Type: Article

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