Gene analysis for longitudinal family data using random-effects models

BMC Proceedings

Volumn 8, Issue , 2014, Pages

  Houwing Duistermaat, Jeanine J ^a   Helmer, Quinta ^a   Balliu, Bruna ^a   Van Den Akker, Erik ^a,b   Tsonaka, Roula ^a   Uh, Hae Won ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b DELFT UNIVERSITY OF TECHNOLOGY   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ABTB1 GENE; ARF4 GENE; ARHGEF3 GENE; B4GALT4 GENE; BAYES THEOREM; BTD GENE; CHROMOSOME 3; CONFERENCE PAPER; DIASTOLIC BLOOD PRESSURE; DNASE1L3 GENE; EFFECT SIZE; FRMD4B GENE; GENE; GENE FREQUENCY; GENETIC ANALYSIS; GENETIC VARIATION; GENOME-WIDE ASSOCIATION STUDY; GENOTYPE; GPR160 GENE; GTDC2 GENE; HUMAN; LONGITUDINAL STUDY; MAP4 GENE; MLH1 GENE; MUC13 GENE; MUSTN1 GENE; NULL HYPOTHESIS; PAK2 GENE; PDCD6I GENE; PHENOTYPE; PPP2R3A GENE; PTPLB GENE; QUANTITATIVE TRAIT LOCUS; RAD18 GENE; RANDOMIZATION; RYBP GENE; SEMA3F GENE; SERP1 GENE; SINGLE NUCLEOTIDE POLYMORPHISM; STOP CODON; VPS8 GENE; ZBTB38 GENE;

EID: 85018193089     PISSN: None     EISSN: 17536561     Source Type: Journal    
DOI: 10.1186/1753-6561-8-S1-S88     Document Type: Conference Paper

References (8)

1. Tsonaka R, van der Helm-vander Mill A, Houwing-Duistermaat JJ: Association tests for the effect of genetic pathways on longitudinal outcomes. Stat Med. 2012, 1190-1202. 31
2. Houwing-Duistermaat JJ, Uh HW, Tsonaka R: Pathway analysis for family data using nested random-effects models. BMC Proc. 2011, 5 (suppl 9): S22-10.1186/1753-6561-5-S9-S22.
3. Ladouceur M, Dastani Z, Aulchenko YS, Greenwood CM, Richards JB: The empirical power of rare variant association methods: results from Sanger sequencing in 1,998 individuals. PLoS Genet. 2012, 8: e1002496-10.1371/journal.pgen.1002496.
4. Wang K, Li M, Hakonarson H: ANNOVAR: functional annotation of genetic variants from next-generation sequencing data. Nucleic Acids Res. 2010, 38: e164-10.1093/nar/gkq603.
5. UCSC Known Genes database. [ http://hgdownload.cse.ucsc.edu ]
6. Almasy L, Dyer TD, Peralta JM, Jun G, Fuchsberger C, Almeida MA, Kent JW, Fowler S, Duggirala R, Blangero J: Data for Genetic Analysis Workshop 18: human whole genome sequence, blood pressure, and simulated phenotypes in extended pedigrees. BMC Proc. 2014, 8 (suppl 2): S2-
7. R program. [ http://www.r-project.org ]
8. Cappola TP, Li M, He J, Ky B, Gilmore J, Qu L, Keating B, Reilly M, Kim CE, Glessner J, et al: Common variants in HSPB7 and FRMD4B associated with advanced heart failure. Circ Cardiovasc Genet. 2010, 147-154. 3