A two-stage mixed-effects model approach for gene-set analyses in candidate gene studies

Statistics in Medicine

Volumn 31, Issue 11-12, 2012, Pages 1190-1202

  Tsonaka, Roula ^a   van der Helm van Mil, Annette H M ^a   Houwing Duistermaat, Jeanine J ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Crossed nested random effects; Longitudinal data

Indexed keywords

ARTICLE; BAYES THEOREM; COMPUTER PROGRAM; CORRELATION ANALYSIS; GENE FREQUENCY; GENE SET ANALYSIS; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENOTYPE; HUMAN; PHENOTYPE; RHEUMATOID ARTHRITIS; SIMULATION; SINGLE NUCLEOTIDE POLYMORPHISM; STATISTICAL MODEL; TWO STAGE MIXED EFFECTS MODEL;

ARTHRITIS, RHEUMATOID; BAYES THEOREM; COMPUTER SIMULATION; GENETIC ASSOCIATION STUDIES; GENETIC PREDISPOSITION TO DISEASE; HUMANS; LONGITUDINAL STUDIES; MODELS, GENETIC; MODELS, STATISTICAL; POLYMORPHISM, SINGLE NUCLEOTIDE; SEVERITY OF ILLNESS INDEX; SOFTWARE;

EID: 84861200999     PISSN: 02776715     EISSN: 10970258     Source Type: Journal    
DOI: 10.1002/sim.4370     Document Type: Article

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