SCOPUS 정보 검색 플랫폼

Volumn 38, Issue 15, 2017, Pages 1229-1237

Are induced fit protein conformational changes caused by ligand-binding predictable? A molecular dynamics investigation

(3) Gao, Cen a Desaphy, Jeremy a Vieth, Michal a

Author keywords

active site flexibility; active site rearrangement; apo holo transition; conformational changes; conformational transition; induced fit; ligand binding; molecular dynamics

Indexed keywords

BINDING SITES; BINS; LIGANDS; PROTEINS;

ACTIVE SITE; APO-HOLO TRANSITION; CONFORMATIONAL CHANGE; CONFORMATIONAL TRANSITIONS; INDUCED FIT; LIGAND BINDING;

MOLECULAR DYNAMICS;

LIGAND; PROTEIN; PROTEIN BINDING;

BINDING SITE; CHEMISTRY; COMPUTER AIDED DESIGN; DRUG DESIGN; DRUG EFFECT; ENZYME ACTIVE SITE; HUMAN; METABOLISM; MOLECULAR DYNAMICS; PROTEIN CONFORMATION; PROTEIN DATABASE; X RAY CRYSTALLOGRAPHY;

BINDING SITES; CATALYTIC DOMAIN; COMPUTER-AIDED DESIGN; CRYSTALLOGRAPHY, X-RAY; DATABASES, PROTEIN; DRUG DESIGN; HUMANS; LIGANDS; MOLECULAR DYNAMICS SIMULATION; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEINS;

EID: 85017544400 PISSN: 01928651 EISSN: 1096987X Source Type: Journal
DOI: 10.1002/jcc.24714 Document Type: Article

Times cited : (11)

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