메뉴 건너뛰기




Volumn 56, Issue 8, 2017, Pages 1992-1998

MIR-27a regulates the TGF-β signaling pathway by targeting SMAD2 and SMAD4 in lung cancer

Author keywords

lung cancer; miR 27a; SMAD2; SMAD4; TGF

Indexed keywords

MESSENGER RNA; MICRORNA; MICRORNA 27A; SMAD2 PROTEIN; SMAD4 PROTEIN; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; MIRN27 MICRORNA, HUMAN; SMAD2 PROTEIN, HUMAN; SMAD4 PROTEIN, HUMAN;

EID: 85017505665     PISSN: 08991987     EISSN: 10982744     Source Type: Journal    
DOI: 10.1002/mc.22655     Document Type: Article
Times cited : (59)

References (23)
  • 1
    • 0141594935 scopus 로고    scopus 로고
    • From developmental disorder to heritable cancer: it's all in the BMP/TGF-beta family
    • Waite KA, Eng C. From developmental disorder to heritable cancer: it's all in the BMP/TGF-beta family. Nat Rev Genet. 2003; 4:763–773.
    • (2003) Nat Rev Genet , vol.4 , pp. 763-773
    • Waite, K.A.1    Eng, C.2
  • 2
    • 77952896646 scopus 로고    scopus 로고
    • TGFbeta signalling: a complex web in cancer progression
    • Ikushima H, Miyazono K. TGFbeta signalling: a complex web in cancer progression. Nat Rev Cancer. 2010; 10:415–424.
    • (2010) Nat Rev Cancer , vol.10 , pp. 415-424
    • Ikushima, H.1    Miyazono, K.2
  • 3
    • 84901782974 scopus 로고    scopus 로고
    • Two faces of TGF-beta1 in breast cancer
    • Zarzynska JM. Two faces of TGF-beta1 in breast cancer. Mediators Inflamm. 2014; 2014:141747.
    • (2014) Mediators Inflamm , vol.2014 , pp. 141747
    • Zarzynska, J.M.1
  • 4
    • 84862757239 scopus 로고    scopus 로고
    • Two sides of the story? Smad4 loss in pancreatic cancer versus head-and-neck cancer
    • Malkoski SP, Wang XJ. Two sides of the story? Smad4 loss in pancreatic cancer versus head-and-neck cancer. FEBS Lett. 2012; 586:1984–1992.
    • (2012) FEBS Lett , vol.586 , pp. 1984-1992
    • Malkoski, S.P.1    Wang, X.J.2
  • 5
    • 58249088751 scopus 로고    scopus 로고
    • MicroRNAs: target recognition and regulatory functions
    • Bartel DP. MicroRNAs: target recognition and regulatory functions. Cell 2009; 136:215–233.
    • (2009) Cell , vol.136 , pp. 215-233
    • Bartel, D.P.1
  • 6
    • 84907915273 scopus 로고    scopus 로고
    • MicroRNA-27a promotes proliferation and suppresses apoptosis by targeting PLK2 in laryngeal carcinoma
    • Tian Y, Fu S, Qiu GB, et al. MicroRNA-27a promotes proliferation and suppresses apoptosis by targeting PLK2 in laryngeal carcinoma. BMC Cancer. 2014; 14:678.
    • (2014) BMC Cancer , vol.14 , pp. 678
    • Tian, Y.1    Fu, S.2    Qiu, G.B.3
  • 7
    • 84951910396 scopus 로고    scopus 로고
    • The Six1 oncoprotein downregulates p53 via concomitant regulation of RPL26 and microRNA-27a-3p
    • Towers CG, Guarnieri AL, Micalizzi DS, et al. The Six1 oncoprotein downregulates p53 via concomitant regulation of RPL26 and microRNA-27a-3p. Nat Commun. 2015; 6:10077.
    • (2015) Nat Commun , vol.6 , pp. 10077
    • Towers, C.G.1    Guarnieri, A.L.2    Micalizzi, D.S.3
  • 8
    • 77956475436 scopus 로고    scopus 로고
    • Cooperative and individualistic functions of the microRNAs in the miR-23a ∼ 27a ∼ 24-2 cluster and its implication in human diseases
    • Chhabra R, Dubey R, Saini N. Cooperative and individualistic functions of the microRNAs in the miR-23a ∼ 27a ∼ 24-2 cluster and its implication in human diseases. Mol Cancer. 2010; 9:232.
    • (2010) Mol Cancer , vol.9 , pp. 232
    • Chhabra, R.1    Dubey, R.2    Saini, N.3
  • 9
    • 84891930466 scopus 로고    scopus 로고
    • MicroRNA-27a functions as a tumor suppressor in esophageal squamous cell carcinoma by targeting KRAS
    • Zhu L, Wang Z, Fan Q, Wang R, Sun Y. MicroRNA-27a functions as a tumor suppressor in esophageal squamous cell carcinoma by targeting KRAS. Oncol Rep. 2014; 31:280–286.
    • (2014) Oncol Rep , vol.31 , pp. 280-286
    • Zhu, L.1    Wang, Z.2    Fan, Q.3    Wang, R.4    Sun, Y.5
  • 10
    • 84967190323 scopus 로고    scopus 로고
    • MicroRNA-27a functions as a tumor suppressor in renal cell carcinoma by targeting epidermal growth factor receptor
    • Li Y, Li J, Sun X, et al. MicroRNA-27a functions as a tumor suppressor in renal cell carcinoma by targeting epidermal growth factor receptor. Oncol Lett. 2016; 11:4217–4223.
    • (2016) Oncol Lett , vol.11 , pp. 4217-4223
    • Li, Y.1    Li, J.2    Sun, X.3
  • 11
    • 84984926970 scopus 로고    scopus 로고
    • Androgen-induced miR-27A acted as a tumor suppressor by targeting MAP2K4 and mediated prostate cancer progression
    • Wan X, Huang W, Yang S, et al. Androgen-induced miR-27A acted as a tumor suppressor by targeting MAP2K4 and mediated prostate cancer progression. Int J Biochem Cell Biol. 2016; 79:249–260.
    • (2016) Int J Biochem Cell Biol , vol.79 , pp. 249-260
    • Wan, X.1    Huang, W.2    Yang, S.3
  • 12
    • 9244239811 scopus 로고    scopus 로고
    • G1 cell-cycle control and cancer
    • Massague J. G1 cell-cycle control and cancer. Nature. 2004; 432:298–306.
    • (2004) Nature , vol.432 , pp. 298-306
    • Massague, J.1
  • 13
    • 84988850898 scopus 로고    scopus 로고
    • MicroRNA-27a-3p is a negative regulator of lung fibrosis by targeting myofibroblast differentiation
    • Cui H, Banerjee S, Xie N, et al. MicroRNA-27a-3p is a negative regulator of lung fibrosis by targeting myofibroblast differentiation. Am J Respir Cell Mol Biol. 2016; 54:843–852.
    • (2016) Am J Respir Cell Mol Biol , vol.54 , pp. 843-852
    • Cui, H.1    Banerjee, S.2    Xie, N.3
  • 14
    • 84928961742 scopus 로고    scopus 로고
    • Tumor suppressor microRNA-27a in colorectal carcinogenesis and progression by targeting SGPP1 and Smad2
    • Bao Y, Chen Z, Guo Y, et al. Tumor suppressor microRNA-27a in colorectal carcinogenesis and progression by targeting SGPP1 and Smad2. PLoS ONE. 2014; 9:105991.
    • (2014) PLoS ONE , vol.9
    • Bao, Y.1    Chen, Z.2    Guo, Y.3
  • 15
    • 57349146677 scopus 로고    scopus 로고
    • MicroRNA-27a functions as an oncogene in gastric adenocarcinoma by targeting prohibitin
    • Liu T, Tang H, Lang Y, Liu M, Li X. MicroRNA-27a functions as an oncogene in gastric adenocarcinoma by targeting prohibitin. Cancer Lett. 2009; 273:233–242.
    • (2009) Cancer Lett , vol.273 , pp. 233-242
    • Liu, T.1    Tang, H.2    Lang, Y.3    Liu, M.4    Li, X.5
  • 16
    • 77957948990 scopus 로고    scopus 로고
    • MiR-27a regulates the growth, colony formation and migration of pancreatic cancer cells by targeting Sprouty2
    • Ma Y, Yu S, Zhao W, Lu Z, Chen J. MiR-27a regulates the growth, colony formation and migration of pancreatic cancer cells by targeting Sprouty2. Cancer Lett. 2010; 298:150–158.
    • (2010) Cancer Lett , vol.298 , pp. 150-158
    • Ma, Y.1    Yu, S.2    Zhao, W.3    Lu, Z.4    Chen, J.5
  • 17
    • 80052518795 scopus 로고    scopus 로고
    • Upregulation of miR-27a contributes to the malignant transformation of human bronchial epithelial cells induced by SV40 small T antigen
    • Wang Q, Li DC, Li ZF, et al. Upregulation of miR-27a contributes to the malignant transformation of human bronchial epithelial cells induced by SV40 small T antigen. Oncogene. 2011; 30:3875–3886.
    • (2011) Oncogene , vol.30 , pp. 3875-3886
    • Wang, Q.1    Li, D.C.2    Li, Z.F.3
  • 18
    • 84859259668 scopus 로고    scopus 로고
    • Alterations in the Smad pathway in human cancers
    • Samanta D, Datta PK. Alterations in the Smad pathway in human cancers. Front Biosci. 2012; 17:1281–1293.
    • (2012) Front Biosci , vol.17 , pp. 1281-1293
    • Samanta, D.1    Datta, P.K.2
  • 19
    • 27944445472 scopus 로고    scopus 로고
    • Restoration of TGF-beta signalling reduces tumorigenicity in human lung cancer cells
    • Anumanthan G, Halder SK, Osada H, et al. Restoration of TGF-beta signalling reduces tumorigenicity in human lung cancer cells. Br J Cancer. 2005; 93:1157–1167.
    • (2005) Br J Cancer , vol.93 , pp. 1157-1167
    • Anumanthan, G.1    Halder, S.K.2    Osada, H.3
  • 20
    • 0034604108 scopus 로고    scopus 로고
    • Heterogeneities in the biological and biochemical functions of Smad2 and Smad4 mutants naturally occurring in human lung cancers
    • Yanagisawa K, Uchida K, Nagatake M, et al. Heterogeneities in the biological and biochemical functions of Smad2 and Smad4 mutants naturally occurring in human lung cancers. Oncogene. 2000; 19:2305–2311.
    • (2000) Oncogene , vol.19 , pp. 2305-2311
    • Yanagisawa, K.1    Uchida, K.2    Nagatake, M.3
  • 21
    • 84974725292 scopus 로고    scopus 로고
    • Prognostic value of SMAD4 in pancreatic cancer: a meta-Analysis
    • Shugang X, Hongfa Y, Jianpeng L, et al. Prognostic value of SMAD4 in pancreatic cancer: a meta-Analysis. Transl Oncol. 2016; 9:1–7.
    • (2016) Transl Oncol , vol.9 , pp. 1-7
    • Shugang, X.1    Hongfa, Y.2    Jianpeng, L.3
  • 22
    • 84924082957 scopus 로고    scopus 로고
    • TGF-beta-activated SMAD3/4 complex transcriptionally upregulates N-cadherin expression in non-small cell lung cancer
    • Yang H, Wang L, Zhao J, et al. TGF-beta-activated SMAD3/4 complex transcriptionally upregulates N-cadherin expression in non-small cell lung cancer. Lung Cancer. 2015; 87:249–257.
    • (2015) Lung Cancer , vol.87 , pp. 249-257
    • Yang, H.1    Wang, L.2    Zhao, J.3
  • 23
    • 85020543458 scopus 로고    scopus 로고
    • MicroRNA-132 inhibits migration, invasion and epithelial-mesenchymal transition by regulating TGFbeta1/Smad2 in human non-small cell lung cancer
    • Zhang JX, Zhai JF, Yang XT, Wang J. MicroRNA-132 inhibits migration, invasion and epithelial-mesenchymal transition by regulating TGFbeta1/Smad2 in human non-small cell lung cancer. Eur Rev Med Pharmac Sci. 2016; 20:3793–3801.
    • (2016) Eur Rev Med Pharmac Sci , vol.20 , pp. 3793-3801
    • Zhang, J.X.1    Zhai, J.F.2    Yang, X.T.3    Wang, J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.