Specific folic-acid targeted photosensitizer. The first step toward intraperitoneal photodynamic therapy for epithelial ovarian cancer;Photosensibilisateur spécifique pour la thérapie photodynamique ciblée des métastases péritonéales des cancers ovariens

Gynecologie Obstetrique Fertilite et Senologie

Volumn 45, Issue 4, 2017, Pages 190-196

  Azais H ^a,b   Frochot, C ^c   Grabarz, A ^b,d   Khodja Bach, S ^b   Colombeau, L ^c   Delhem, N ^d   Mordon, S ^b   Collinet, P ^b  

^a ASSISTANCE PUBLIQUE HÔPITAUX DE PARIS   (France)

^b LILLE UNIVERSITY HOSPITAL   (France)

^c UNIVERSITÉ DE LORRAINE   (France)

^d UNIV LILLE   (France)

Author keywords

Fluorescence; Folate receptor; Ovarian cancer; Photodynamic therapy; Photosensitizer

Indexed keywords

FOLATE RECEPTOR; FOLIC ACID; PHOTOSENSITIZING AGENT;

ARTICLE; CANCER CHEMOTHERAPY; CANCER SURGERY; CELL DEATH; CYTOREDUCTIVE SURGERY; FEMALE; HUMAN; IN VITRO STUDY; IN VIVO STUDY; MULTIMODALITY CANCER THERAPY; NONHUMAN; OVARY CARCINOMA; OVARY METASTASIS; PHOTODYNAMIC THERAPY; PRECLINICAL STUDY; TUMOR REGRESSION; ANIMAL; DRUG EFFECT; FISCHER 344 RAT; METASTASIS; MOUSE; NECROSIS; NEOPLASM; OVARY TUMOR; PATHOLOGY; PERITONEUM TUMOR; PHOTOCHEMOTHERAPY; PREVENTION AND CONTROL; PROCEDURES; RAT; SECONDARY; TUMOR CELL LINE; TUMOR RECURRENCE;

ANIMALS; CELL LINE, TUMOR; COMBINED MODALITY THERAPY; CYTOREDUCTION SURGICAL PROCEDURES; FEMALE; FOLATE RECEPTORS, GPI-ANCHORED; FOLIC ACID; HUMANS; MICE; NECROSIS; NEOPLASM METASTASIS; NEOPLASM RECURRENCE, LOCAL; NEOPLASMS, GLANDULAR AND EPITHELIAL; OVARIAN NEOPLASMS; PERITONEAL NEOPLASMS; PHOTOCHEMOTHERAPY; PHOTOSENSITIZING AGENTS; RATS; RATS, INBRED F344;

EID: 85017433586     PISSN: 24687197     EISSN: 24687189     Source Type: Journal    
DOI: 10.1016/j.gofs.2017.02.010     Document Type: Article

References (25)

1. [1] Eisenkop, S.M., Spirtos, N.M., Lin, W-C.M., “Optimal” cytoreduction for advanced epithelial ovarian cancer: a commentary. Gynecol Oncol 103:1 (2006), 329–335.
2. [2] Vergote, I., Amant, F., Kristensen, G., Ehlen, T., Reed, N.S., Casado, A., Primary surgery or neoadjuvant chemotherapy followed by interval debulking surgery in advanced ovarian cancer. Eur J Cancer 47:Supplement 3 (2011), S88–S92.
3. [3] Al Rawahi, T., Lopes, A.D., Bristow, R.E., Bryant, A., Elattar, A., Chattopadhyay, S., et al. Surgical cytoreduction for recurrent epithelial ovarian cancer. Cochrane Database Syst Rev, 2, 2013, CD008765.
4. [4] Querleu, D., Gladieff, L., Ferron, G., Rougé, P., [Towards a new standard in cytoreductive surgery for advanced ovarian cancer]. Bull Cancer (Paris) 96:12 (2009), 1175–1182.
5. [5] Azaïs, H., Estevez, J.P., Foucher, P., Kerbage, Y., Mordon, S., Collinet, P., Dealing with microscopic peritoneal metastases of epithelial ovarian cancer. A surgical challenge. Surg Oncol 26:1 (2017), 46–52.
6. [6] Azaïs, H., Betrouni, N., Mordon, S., Collinet, P., Targeted approaches and innovative illumination solutions: a new era for photodynamic therapy applications in gynecologic oncology?. Photodiagnosis Photodyn Ther 13 (2016), 128–129.
7. [7] Rose, G.S., Tocco, L.M., Granger, G.A., DiSaia, P.J., Hamilton, T.C., Santin, A.D., et al. Development and characterization of a clinically useful animal model of epithelial ovarian cancer in the Fischer 344 rat. Am J Obstet Gynecol 175:3 Pt 1 (1996), 593–599.
8. [8] Azaïs, H., Queniat, G., Bonner, C., Kerdraon, O., Tardivel, M., Jetpisbayeva, G., et al. Fischer 344 rat: a preclinical model for epithelial ovarian cancer folate-targeted therapy. Int J Gynecol Cancer 25:7 (2015), 1194–1200.
9. [9] Werner, M.E., Karve, S., Sukumar, R., Cummings, N.D., Copp, J.A., Chen, R.C., et al. Folate-targeted nanoparticle delivery of chemo- and radiotherapeutics for the treatment of ovarian cancer peritoneal metastasis. Biomaterials 32:33 (2011), 8548–8554.
10. [10] Müller, C., Schibli, R., Krenning, E.P., de Jong, M., Pemetrexed improves tumor selectivity of 111In-DTPA-folate in mice with folate receptor-positive ovarian cancer. J Nucl Med 49:4 (2008), 623–629.
11. [11] Azaïs, H., Moussaron, A., Khodja Bach, S., Bassil, A., Betrouni, N., Frochot, C., et al. [FRα: a target for prophylactic photodynamic therapy of ovarian peritoneal metastasis?]. Bull Cancer (Paris) 101:12 (2014), 1109–1113.
12. [12] Cochrane, C., Mordon, S.R., Lesage, J.C., Koncar, V., New design of textile light diffusers for photodynamic therapy. Mater Sci Eng C 33:3 (2013), 1170–1175.
13. [13] Mordon S, Cochrane C, Vignion AS, Betrouni N, Mortier L, Koncar V. Light emitting fabric technologies for photodynamic therapy. Photodiagnosis Photodyn Ther 2015;12(1):1–8. Available from: http://www.sciencedirect.com/science/article/pii/S1572100014001380].
14. [14] Sudimack, J., Lee, R.J., Targeted drug delivery via the folate receptor. Adv Drug Deliv Rev 41:2 (2000), 147–162.
15. [15] Leamon, C.P., Low, P.S., Delivery of macromolecules into living cells: a method that exploits folate receptor endocytosis. Proc Natl Acad Sci U S A 88:13 (1991), 5572–5576.
16. [16] Leamon, C.P., Low, P.S., Folate-mediated targeting: from diagnostics to drug and gene delivery. Drug Discov Today 6:1 (2001), 44–51.
17. [17] Azaïs, H., Schmitt, C., Tardivel, M., Kerdraon, O., Stallivieri, A., Frochot, C., et al. Assessment of the specificity of a new folate-targeted photosensitizer for peritoneal metastasis of epithelial ovarian cancer to enable intraperitoneal photodynamic therapy. A preclinical study. Photodiagnosis Photodyn Ther 13 (2016), 130–138.
18. [18] Guyon, L., Farine, M.-O., Lesage, J.C., Gevaert, A.-M., Simonin, S., Schmitt, C., et al. Photodynamic therapy of ovarian cancer peritoneal metastasis with hexaminolevulinate: a toxicity study. Photodiagnosis Photodyn Ther 11:3 (2014), 265–274.
19. [19] Kennedy, M.D., Jallad, K.N., Thompson, D.H., Ben-Amotz, D., Low, P.S., Optical imaging of metastatic tumors using a folate-targeted fluorescent probe. J Biomed Opt 8:4 (2003), 636–641.
20. [20] Guyon, L., Ascencio, M., Collinet, P., Mordon, S., Photodiagnosis and photodynamic therapy of peritoneal metastasis of ovarian cancer. Photodiagnosis Photodyn Ther 9:1 (2012), 16–31.
21. [21] van Dam, G.M., Themelis, G., Crane, L.M.A., Harlaar, N.J., Pleijhuis, R.G., Kelder, W., et al. Intraoperative tumor-specific fluorescence imaging in ovarian cancer by folate receptor-α targeting: first in-human results. Nat Med 17:10 (2011), 1315–1319.
22. [22] Tummers, Q.R.J.G., Hoogstins, C.E.S., Gaarenstroom, K.N., de Kroon, C.D., van Poelgeest, M.I.E., Vuyk, J., et al. Intraoperative imaging of folate receptor alpha positive ovarian and breast cancer using the tumor-specific agent EC17. Oncotarget 7:22 (2016), 32144–32155.
23. [23] Hoogstins, C.E.S., Tummers, Q.R.J.G., Gaarenstroom, K.N., de Kroon, C.D., Trimbos, J.B.M.Z., Bosse, T., et al. A novel tumor-specific agent for intraoperative near-infrared fluorescence imaging: a translational study in healthy volunteers and patients with ovarian cancer. Am Assoc Cancer Res 22:12 (2016), 2929–2938.
24. [24] Tummers, Q.R.J.G., Hoogstins, C.E.S., Peters, A.A.W., de Kroon, C.D., Trimbos, J.B.M.Z., van de Velde, C.J.H., et al. The value of intraoperative near-infrared fluorescence imaging based on enhanced permeability and retention of indocyanine green: feasibility and false-positives in ovarian cancer. PLoS One, 10(6), 2015, e0129766, 10.1371/journal.pone.0129766.
25. [25] Liu, Y., Endo, Y., Fujita, T., Ishibashi, H., Nishioka, T., Canbay, E., et al. Cytoreductive surgery under aminolevulinic acid-mediated photodynamic diagnosis plus hyperthermic intraperitoneal chemotherapy in patients with peritoneal carcinomatosis from ovarian cancer and primary peritoneal carcinoma: results of a phase I trial. Ann Surg Oncol 21:13 (2014), 4256–4262.