Using gonadotropin-releasing hormone agonist before frozen embryo transfer may improve ongoing pregnancy rates in hyperandrogenic polycystic ovary syndrome women

Gynecological Endocrinology

Volumn 33, Issue 9, 2017, Pages 686-689

  Tsai, Hsiao Wen ^a,b,c   Wang, Peng Hui ^b,d,e   Lin, Li Te ^a,b,f   Chen, San Nung ^a   Tsui, Kuan Hao ^a,b,f,g  

^a KAOHSIUNG VETERANS GENERAL HOSPITAL   (Taiwan)

^b NATIONAL YANG MING UNIVERSITY   (Taiwan)

^c KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^d TAIPEI VETERANS GENERAL HOSPITAL   (Taiwan)

^e CHINA MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^f NATIONAL SUN YAT SEN UNIVERSITY   (Taiwan)

^g TAJEN UNIVERSITY   (Taiwan)

Author keywords

Frozen thawed embryo transfer; hyperandrogenism; polycystic ovary syndrome; pregnancy

Indexed keywords

DYDROGESTERONE; ESTRADIOL VALERATE; LEUPRORELIN; PROGESTERONE DERIVATIVE; FERTILITY PROMOTING AGENT;

ADULT; ARTICLE; CONFIDENCE INTERVAL; CONTROLLED STUDY; EMBRYO TRANSFER; FEMALE; FREEZE THAWING; HORMONAL THERAPY; HUMAN; MAJOR CLINICAL STUDY; OVARY POLYCYSTIC DISEASE; PREGNANCY OUTCOME; PREGNANCY RATE; PREMEDICATION; PRIORITY JOURNAL; RETROSPECTIVE STUDY; TREATMENT OUTCOME; FEMALE INFERTILITY; HYPERANDROGENISM; PATHOPHYSIOLOGY; PREGNANCY; PROCEDURES;

ADULT; EMBRYO TRANSFER; FEMALE; FERTILITY AGENTS, FEMALE; HUMANS; HYPERANDROGENISM; INFERTILITY, FEMALE; LEUPROLIDE; POLYCYSTIC OVARY SYNDROME; PREGNANCY; PREGNANCY RATE; RETROSPECTIVE STUDIES; TREATMENT OUTCOME;

EID: 85017235145     PISSN: 09513590     EISSN: 14730766     Source Type: Journal    
DOI: 10.1080/09513590.2017.1307961     Document Type: Article

References (25)

1. Franks S., Polycystic ovary syndrome. N Engl J Med 1995;333:853–61
2. Goodarzi MO, Dumesic DA, Chazenbalk G, Azziz R., Polycystic ovary syndrome: etiology, pathogenesis and diagnosis. Nat Rev Endocrinol 2011;7:219–31
3. Hart R., Polycystic ovarian syndrome–prognosis and treatment outcomes. Curr Opin Obstet Gynecol 2007;19:529–35
4. Pundir J, Sunkara SK, El-Toukhy T, Khalaf Y., Meta-analysis of GnRH antagonist protocols: do they reduce the risk of OHSS in PCOS? Reprod Biomed Online 2012;24:6–22
5. Wong KM, Mastenbroek S, Repping S., Cryopreservation of human embryos and its contribution to in vitro fertilization success rates. Fertil Steril 2014;102:19–26
6. Chen H, Wang Y, Lyu Q, et al. Comparison of live-birth defects after luteal-phase ovarian stimulation vs. conventional ovarian stimulation for in vitro fertilization and vitrified embryo transfer cycles. Fertil Steril 2015;103:1194–201 e2
7. Ashrafi M, Jahangiri N, Hassani F, et al. The factors affecting the outcome of frozen-thawed embryo transfer cycle. Taiwanese J Obstet Gynecol 2011;50:159–64
8. Savaris RF, Groll JM, Young SL, et al. Progesterone resistance in PCOS endometrium: a microarray analysis in clomiphene citrate-treated and artificial menstrual cycles. J Clin Endocrinol Metab 2011;96:1737–46
9. Gonzalez D, Thackeray H, Lewis PD, et al. Loss of WT1 expression in the endometrium of infertile PCOS patients: a hyperandrogenic effect? J Clin Endocrinol Metab 2012;97:957–66
10. Cermik D, Selam B, Taylor HS., Regulation of HOXA-10 expression by testosterone in vitro and in the endometrium of patients with polycystic ovary syndrome. J Clin Endocrinol Metab 2003;88:238–43
11. Niu Z, Chen Q, Sun Y, Feng Y., Long-term pituitary downregulation before frozen embryo transfer could improve pregnancy outcomes in women with adenomyosis. Gynecol Endocrinol 2013;29:1026–30
12. Mijatovic V, Florijn E, Halim N, et al. Adenomyosis has no adverse effects on IVF/ICSI outcomes in women with endometriosis treated with long-term pituitary down-regulation before IVF/ICSI. Eur J Obstet Gynecol Reprod Biol 2010;151:62–5
13. Merseburger AS, Hupe MC., An update on triptorelin: current thinking on androgen deprivation therapy for prostate cancer. Adv Ther 2016;33:1072–93
14. Rotterdam EA-SPcwg. Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome (PCOS). Hum Reprod 2004;19:41–7
15. Okon MA, Laird SM, Tuckerman EM, Li TC., Serum androgen levels in women who have recurrent miscarriages and their correlation with markers of endometrial function. Fertil Steril 1998;69:682–90
16. Homburg R, Armar NA, Eshel A, et al. Influence of serum luteinising hormone concentrations on ovulation, conception, and early pregnancy loss in polycystic ovary syndrome. BMJ 1988;297:1024–6
17. Tulppala M, Stenman UH, Cacciatore B, Ylikorkala O., Polycystic ovaries and levels of gonadotrophins and androgens in recurrent miscarriage: prospective study in 50 women. Br J Obstet Gynaecol 1993;100:348–52
18. Mokhtar HM, Giribabu N, Muniandy S, Salleh N., Testosterone decreases the expression of endometrial pinopode and l-selectin ligand (MECA-79) in adult female rats during uterine receptivity period. Int J Clin Exp Pathol 2014;7:1967–76
19. Kollmann M, Martins WP, Lima ML, et al. Strategies for improving outcome of assisted reproduction in women with polycystic ovary syndrome: systematic review and meta-analysis. Ultrasound Obstet Gynecol 2016;48:709–18
20. Fedorcsak P, Dale PO, Storeng R, et al. The effect of metformin on ovarian stimulation and in vitro fertilization in insulin-resistant women with polycystic ovary syndrome: an open-label randomized cross-over trial. Gynecol Endocrinol 2003;17:207–14
21. Al-Biate MA., Effect of metformin on early pregnancy loss in women with polycystic ovary syndrome. Taiwan J Obstet Gynecol 2015;54:266–9
22. Rashidi B, Haghollahi F, Shariat M, Zayerii F., The effects of calcium-vitamin D and metformin on polycystic ovary syndrome: a pilot study. Taiwanese J Obstet Gynecol 2009;48:142–7
23. Groenewoud ER, Cantineau AE, Kollen BJ, et al. What is the optimal means of preparing the endometrium in frozen-thawed embryo transfer cycles? A systematic review and meta-analysis. Hum Reprod Updat 2013;19:458–70
24. Azziz R, Carmina E, Dewailly D, et al. Positions statement: criteria for defining polycystic ovary syndrome as a predominantly hyperandrogenic syndrome: an androgen excess society guideline. J Clin Endocrinol Metab 2006;91:4237–45
25. Miller KK, Rosner W, Lee H, et al. Measurement of free testosterone in normal women and women with androgen deficiency: comparison of methods. J Clin Endocrinol Metab 2004;89:525–33