Antagonism of profibrotic microRNA-21 improves outcome of murine chronic renal allograft dysfunction

Kidney International

Volumn 92, Issue 3, 2017, Pages 646-656

  Schauerte, Celina ^a   Hübner, Anika ^a   Rong, Song ^a   Wang, Shijun ^a   Shushakova, Nelli ^a   Mengel, Michael ^b   Dettling, Angela ^a   Bang, Claudia ^a   Scherf, Kristian ^a   Koelling, Malte ^a   Melk, Anette ^a   Haller, Hermann ^a   Thum, Thomas ^a,c   Lorenzen, Johan M ^a,d  

^a HANNOVER MEDICAL SCHOOL   (Germany)

^b UNIVERSITY OF ALBERTA   (Canada)

^c NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

^d UNIVERSITY HOSPITAL ZURICH   (Switzerland)

Author keywords

chronic renal allograft dysfunction; IL 6; microRNA 21; Notch2

Indexed keywords

INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MICRORNA 21; MICRORNA 21A 5P; NOTCH2 RECEPTOR; STAT3 PROTEIN; UNCLASSIFIED DRUG; BIOLOGICAL MARKER; LOCKED NUCLEIC ACID; MICRORNA; MIRN-21 MICRORNA, MOUSE; NOTCH2 PROTEIN, MOUSE; OLIGONUCLEOTIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHRONIC ALLOGRAFT NEPHROPATHY; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; FEMALE; FIBROBLAST; IN VITRO STUDY; KIDNEY FUNCTION; KIDNEY TRANSPLANTATION; LUCIFERASE ASSAY; MACROPHAGE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; UPREGULATION; ALLOGRAFT; ALLOTRANSPLANTATION; ANIMAL; ANTAGONISTS AND INHIBITORS; BAGG ALBINO MOUSE; C57BL MOUSE; CHRONIC DISEASE; COCULTURE; DISEASE MODEL; DOWN REGULATION; FIBROSIS; GENE EXPRESSION PROFILING; GENETICS; GRAFT REJECTION; GRAFT SURVIVAL; HUMAN; KIDNEY; METABOLISM; PATHOLOGY;

ALLOGRAFTS; ANIMALS; BIOMARKERS; CHRONIC DISEASE; COCULTURE TECHNIQUES; DISEASE MODELS, ANIMAL; DOWN-REGULATION; FEMALE; FIBROBLASTS; FIBROSIS; GENE EXPRESSION PROFILING; GRAFT REJECTION; GRAFT SURVIVAL; HUMANS; KIDNEY; KIDNEY TRANSPLANTATION; MACROPHAGES; MALE; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICRORNAS; OLIGONUCLEOTIDES; RECEPTOR, NOTCH2; TRANSPLANTATION, HOMOLOGOUS; UP-REGULATION;

EID: 85017186278     PISSN: 00852538     EISSN: 15231755     Source Type: Journal    
DOI: 10.1016/j.kint.2017.02.012     Document Type: Article

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