Diurnal and long-term variation in plasma concentrations and renal clearances of circulating markers of kidney proximal tubular secretion

Clinical Chemistry

Volumn 63, Issue 4, 2017, Pages 915-923

  Rivara, Matthew B ^a,b   Zelnick, Leila R ^a,b   Hoofnagle, Andrew N ^a,c   Newitt, Rick ^a   Tracy, Russell P ^a,d   Kratz, Mario ^b,c,e   Weigle, David S ^b   Kestenbaum, Bryan R ^a,b,e  

^a Kidney Research Institute   (United States)

^b UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF WASHINGTON   (United States)

^d UNIVERSITY OF VERMONT COLLEGE OF MEDICINE   (United States)

^e Fred Hutchinson Cancer Research Center   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 CRESOL SULFATE; BIOLOGICAL MARKER; CINNAMOYLGLYCINE; CREATININE; CYSTATIN C; GLYCINE DERIVATIVE; HIPPURIC ACID; INDICAN; PARA CRESOL; UNCLASSIFIED DRUG; 4-CRESOL SULFATE; CRESOL; GLYCINE; HIPPURIC ACID DERIVATIVE; SULFATE;

ADULT; ARTICLE; BLOOD LEVEL; CIRCADIAN RHYTHM; CLINICAL ARTICLE; ESTIMATED GLOMERULAR FILTRATION RATE; FEMALE; FOLLOW UP; HUMAN; KIDNEY PROXIMAL TUBULE; KIDNEY TUBULE EXCRETION; LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY; MALE; RENAL CLEARANCE; URINE LEVEL; ANALOGS AND DERIVATIVES; BLOOD; CHEMISTRY; LIQUID CHROMATOGRAPHY; METABOLISM; SECRETION (PROCESS); TANDEM MASS SPECTROMETRY;

ADULT; BIOMARKERS; CHROMATOGRAPHY, LIQUID; CRESOLS; FEMALE; GLYCINE; HIPPURATES; HUMANS; INDICAN; KIDNEY TUBULES, PROXIMAL; MALE; SULFURIC ACID ESTERS; TANDEM MASS SPECTROMETRY;

EID: 85017021744     PISSN: 00099147     EISSN: 15308561     Source Type: Journal    
DOI: 10.1373/clinchem.2016.260117     Document Type: Article

References (36)

1. Levey AS, de Jong PE, Coresh J, El Nahas M, Astor BC, Matsushita K, et al. The definition, classification, and prognosis of chronic kidney disease: A KDIGO Controversies Conference report. Kidney Int 2011; 80: 17-28.
2. Levey AS, Bosch JP, Lewis JB, Greene T, Rogers N, Roth D.A more accurate method to estimate glomerular filtration rate from serum creatinine: A new prediction equation. Ann Intern Med 1999; 130: 461-70. Authors are on behalf of Modification of Diet in Renal Disease Study Group.
3. Levey AS, Stevens LA, Schmid CH, Zhang YL, Castro AF, Feldman HI, et al. A new equation to estimate glomerular filtration rate. Ann Intern Med 2009; 150: 604-12.
4. Inker LA, Schmid CH, Tighiouart H, Eckfeldt JH, Feldman HI, Greene T, et al. Estimating glomerular filtration rate from serum creatinine and cystatin C. N Engl J Med 2012; 367: 20-9.
5. Nolin TD, Naud J, Leblond FA, Pichette V. Emerging evidence of the impact of kidney disease on drug metabolism and transport. Clin Pharmacol Ther 2008; 83: 898-903.
6. Ramezani A, Raj DS. The gut microbiome, kidney disease, and targeted interventions. J Am Soc Nephrol 2014; 25: 657-70.
7. Ramezani A, Massy ZA, Meijers B, Evenepoel P, Vanholder R, Raj DS. Role of the gut microbiome in uremia: A potential therapeutic target. Am J Kidney Dis 2016; 67: 483-98.
8. Nigam SK,WuW, Bush KT, Hoenig MP, Blantz RC, Bhatnagar V. Handling of drugs, metabolites, and uremic toxins by kidney proximal tubule drug transporters. Clin J Am Soc Nephrol 2015; 10: 2039-49.
9. Meyer TW, Hostetter TH. Uremia. N Engl J Med 2007; 357: 1316-25.
10. Meyer TW, Hostetter TH. Approaches to Uremia. J Am Soc Nephrol 2014; 25: 2151-8.
11. Rossi M, Campbell KL, Johnson DW, Stanton T, Vesey DA, Coombes JS, et al. Protein-bound uremic toxins, inflammation and oxidative stress: A cross-sectional study in stage 3-4 chronic kidney disease. Arch Med Res 2014; 45: 309-17.
12. Suchy-Dicey AM, Laha T, Hoofnagle A, Newitt R, Sirich TL, Meyer TW, et al. Tubular secretion in CKD. J Am Soc Nephrol 2016; 27: 2148-55.
13. Poesen R, Claes K, Evenepoel P, Loor H de, Augustijns P, Kuypers D, et al. Microbiota-derived phenylacetylglutamine associates with overall mortality and cardiovascular disease in patients with CKD. J AmSoc Nephrol 2016; 27: 3479-87.
14. Poesen R, Viaene L, Verbeke K, Claes K, Bammens B, Sprangers B, et al. Renal clearance and intestinal generation of p-cresyl sulfate and indoxyl sulfate in CKD. Clin J Am Soc Nephrol 2013; 8: 1508-14.
15. Putt TL, Duffull SB, Schollum JBW, Walker RJ. GFR may not accurately predict aspects of proximal tubule drug handling. Eur J Clin Pharmacol 2014; 70: 1221-6.
16. Sirich TL, Funk BA, Plummer NS, Hostetter TH, Meyer TW. Prominent accumulation in hemodialysis patients of solutes normally cleared by tubular secretion. J Am Soc Nephrol 2014; 25: 615-22.
17. Sirich TL, Aronov PA, Plummer NS, Hostetter TH, Meyer TW. Numerous protein-bound solutes are cleared by the kidney with high efficiency. Kidney Int 2013; 84: 585-90.
18. Kratz M, Callahan HS, Yang PY, Matthys CC, Weigle DS. Dietary n-3-polyunsaturated fatty acids and energy balance in overweight or moderately obese men and women: A randomized controlled trial. Nutr Metab (Lond) 2009; 6: 24.
19. Kratz M, Swarbrick MM, Callahan HS, Matthys CC, Havel PJ, Weigle DS. Effect of dietary n-3 polyunsaturated fatty acids on plasma total and high-molecularweight adiponectin concentrations in overweight to moderately obese men and women. Am J Clin Nutr 2008; 87: 347-53.
20. Reed AH, Henry RJ, Mason WB. Influence of statistical method used on the resulting estimate of normal range. Clin Chem 1971; 17: 275-84.
21. Fraser GG, Harris EK. Generation and application of data on biological variation in clinical chemistry. Crit Rev Clin Lab Sci 1989; 27: 409-37.
22. Røraas T, Petersen PH, Sandberg S. Confidence intervals and power calculations for within-person biologi-cal variation: Effect of analytical imprecision, number of replicates, number of samples, and number of individuals. Clin Chem 2012; 58: 1306-13.
23. Burdick R, Graybill F. Confidence intervals on variance components. New York: Marcel Dekker; 1992.
24. Fokkema MR, Herrmann Z, Muskiet FAJ, Moecks J. Reference change values for brain natriuretic peptides revisited. Clin Chem 2006; 52: 1602-3.
25. Walser M. Creatinine excretion as a measure of protein nutrition in adults of varying age. J Parenter Enter Nutr 1987; 11: 73S-78S.
26. Meijers BKI, Claes K, Bammens B, Loor H de, Viaene L, Verbeke K, et al. p-Cresol and cardiovascular risk in mild-To-moderate kidney disease. Clin J Am Soc Nephrol 2010; 5: 1182-9.
27. Meijers BKI, Bammens B, De Moor B, Verbeke K, Vanrenterghem Y, Evenepoel P. Free p-cresol is associated with cardiovascular disease in hemodialysis patients. Kidney Int 2008; 73: 1174-80.
28. Meijers BKI, Van kerckhoven S, Verbeke K, Dehaen W, Vanrenterghem Y, Hoylaerts MF, et al. The uremic retention solute p-cresyl sulfate and markers of endothelial damage. Am J Kidney Dis 2009; 54: 891-901.
29. Cao XS, Chen J, Zou JZ, Zhong YH, Teng J, Ji J, et al. Association of indoxyl sulfate with heart failure among patients on hemodialysis. Clin J AmSoc Nephrol 2015; 10: 111-9.
30. Wu IW, Hsu KH, Lee CC, Sun CY, Hsu HJ, Tsai CJ, et al. p-cresyl sulphate and indoxyl sulphate predict progression of chronic kidney disease. Nephrol Dial Transplant 2011; 26: 938-47.
31. Hsu HJ, Yen CH, Chen CK, Wu IW, Lee CC, Sun CY, et al. Association between uremic toxins and depression in patients with chronic kidney disease undergoing maintenance hemodialysis. Gen Hosp Psychiatry 2013; 35: 23-7.
32. Wu CC, Hsieh MY, Hung SC, Kuo KL, Tsai TH, Lai CL, et al. Serum indoxyl sulfate associates with postangioplasty thrombosis of dialysis grafts. J Am Soc Nephrol 2015; 27: 1254-64.
33. Duan P, You G. Short-Term regulation of organic anion transporters. Pharmacol Ther 2010; 125: 55-61.
34. Toffaletti JG, McDonnell EH. Variation of serum creatinine, cystatin C, and creatinine clearance tests in persons with normal renal function. Clin Chim Acta 2008; 395: 115-9.
35. Gowans EM, Fraser CG. Biological variation of serum and urine creatinine and creatinine clearance: Ramifications for interpretation of results and patient care. Ann Clin Biochem 1988; 25: 259-63.
36. Agarwal R. Ambulatory GFR measurement with cold iothalamate in adults with chronic kidney disease.AmJ Kidney Dis 2003; 41: 752-9.