-
1
-
-
84943592745
-
Transmission: development, and plasticity of synapses
-
1 Harris, K.P., Littleton, J.T., Transmission: development, and plasticity of synapses. Genetics 201 (2015), 345–375.
-
(2015)
Genetics
, vol.201
, pp. 345-375
-
-
Harris, K.P.1
Littleton, J.T.2
-
2
-
-
0017089101
-
Properties of the larval neuromuscular junction in Drosophila melanogaster
-
2 Jan, L.Y., Jan, Y.N., Properties of the larval neuromuscular junction in Drosophila melanogaster. J Physiol 262 (1976), 189–214.
-
(1976)
J Physiol
, vol.262
, pp. 189-214
-
-
Jan, L.Y.1
Jan, Y.N.2
-
3
-
-
84896420088
-
Development and plasticity of the Drosophila larval neuromuscular junction
-
3 Menon, K.P., Carrillo, R.A., Zinn, K., Development and plasticity of the Drosophila larval neuromuscular junction. Wiley Interdiscip Rev Dev Biol 2 (2013), 647–670.
-
(2013)
Wiley Interdiscip Rev Dev Biol
, vol.2
, pp. 647-670
-
-
Menon, K.P.1
Carrillo, R.A.2
Zinn, K.3
-
4
-
-
84856475630
-
Experimental methods for examining synaptic plasticity in Drosophila
-
4 Olsen, D.P., Keshishian, H., Experimental methods for examining synaptic plasticity in Drosophila. Cold Spring Harb Protoc 2012 (2012), 162–173.
-
(2012)
Cold Spring Harb Protoc
, vol.2012
, pp. 162-173
-
-
Olsen, D.P.1
Keshishian, H.2
-
5
-
-
0025513585
-
Morphological plasticity of motor axons in Drosophila mutants with altered excitability
-
5 Budnik, V., Zhong, Y., Wu, C., Morphological plasticity of motor axons in Drosophila mutants with altered excitability. J Neurosci 10 (1990), 3754–3768.
-
(1990)
J Neurosci
, vol.10
, pp. 3754-3768
-
-
Budnik, V.1
Zhong, Y.2
Wu, C.3
-
6
-
-
0042343813
-
Experience-dependent strengthening of Drosophila neuromuscular junctions
-
6 Sigrist, S.J., et al. Experience-dependent strengthening of Drosophila neuromuscular junctions. J Neurosci 23 (2003), 6546–6556.
-
(2003)
J Neurosci
, vol.23
, pp. 6546-6556
-
-
Sigrist, S.J.1
-
7
-
-
84886645072
-
Spontaneous and evoked release are independently regulated at individual active zones
-
High spatial resolution imaging of synaptic transmission using membrane-targeted calcium sensors at the larval NMJ reveals that although nearly half of the active zones display both spontaneous and evoked glutamate release, the remaining sites are segregated in to stimulus dependent and independent active zones.
-
7•• Melom, J.E., et al. Spontaneous and evoked release are independently regulated at individual active zones. J Neurosci 33 (2013), 7253–7263 High spatial resolution imaging of synaptic transmission using membrane-targeted calcium sensors at the larval NMJ reveals that although nearly half of the active zones display both spontaneous and evoked glutamate release, the remaining sites are segregated in to stimulus dependent and independent active zones.
-
(2013)
J Neurosci
, vol.33
, pp. 7253-7263
-
-
Melom, J.E.1
-
8
-
-
84899846239
-
Miniature neurotransmission regulates Drosophila synaptic structural maturation
-
A complex series of experiments used to separate spontaneous and evoked glutamate release at the larval NMJ suggests that miniature events are largely responsible to stimulate synaptic growth via cytoskeletal effectors.
-
8•• Choi, B.J., et al. Miniature neurotransmission regulates Drosophila synaptic structural maturation. Neuron 82 (2014), 618–634 A complex series of experiments used to separate spontaneous and evoked glutamate release at the larval NMJ suggests that miniature events are largely responsible to stimulate synaptic growth via cytoskeletal effectors.
-
(2014)
Neuron
, vol.82
, pp. 618-634
-
-
Choi, B.J.1
-
9
-
-
84897693151
-
Neurotransmission: spontaneous and evoked release filing for divorce
-
9 Walter, A.M., Haucke, V., Sigrist, S.J., Neurotransmission: spontaneous and evoked release filing for divorce. Curr Biol 24 (2014), R192–R194.
-
(2014)
Curr Biol
, vol.24
, pp. R192-R194
-
-
Walter, A.M.1
Haucke, V.2
Sigrist, S.J.3
-
10
-
-
0033118555
-
Watching a synapse grow: noninvasive confocal imaging of synaptic growth in Drosophila
-
10 Zito, K., et al. Watching a synapse grow: noninvasive confocal imaging of synaptic growth in Drosophila. Neuron 22 (1999), 719–729.
-
(1999)
Neuron
, vol.22
, pp. 719-729
-
-
Zito, K.1
-
11
-
-
40249094509
-
Rapid activity-dependent modifications in synaptic structure and function require bidirectional Wnt signaling
-
Pioneering work on Wnt signaling at the Drosophila NMJ introduced the spaced potassium assay for activity induced bouton budding and showed that Wg is required for this process.
-
11•• Ataman, B., et al. Rapid activity-dependent modifications in synaptic structure and function require bidirectional Wnt signaling. Neuron 57 (2008), 705–718 Pioneering work on Wnt signaling at the Drosophila NMJ introduced the spaced potassium assay for activity induced bouton budding and showed that Wg is required for this process.
-
(2008)
Neuron
, vol.57
, pp. 705-718
-
-
Ataman, B.1
-
12
-
-
84896299753
-
Retrograde BMP signaling modulates rapid activity-dependent synaptic growth via presynaptic LIM kinase regulation of cofilin
-
Genetic analysis of requirements for activity-induced bouton formation shows that non-cannonical BMP signaling is required and associated with formation of cytoskeletal assembly.
-
12• Piccioli, Z.D., Littleton, J.T., Retrograde BMP signaling modulates rapid activity-dependent synaptic growth via presynaptic LIM kinase regulation of cofilin. J Neurosci 34 (2014), 4371–4381 Genetic analysis of requirements for activity-induced bouton formation shows that non-cannonical BMP signaling is required and associated with formation of cytoskeletal assembly.
-
(2014)
J Neurosci
, vol.34
, pp. 4371-4381
-
-
Piccioli, Z.D.1
Littleton, J.T.2
-
13
-
-
84905689739
-
Synapsin regulates activity-dependent outgrowth of synaptic boutons at the Drosophila neuromuscular junction
-
Correlated light and electron microscopy of NMJ structure following spaced stimulation shows that synaptic vesicle entry into nascent boutons occurs very early in the process, and that PKA and Synapsin are required for this process.
-
13• Vasin, A., et al. Synapsin regulates activity-dependent outgrowth of synaptic boutons at the Drosophila neuromuscular junction. J Neurosci 34 (2014), 10554–10563 Correlated light and electron microscopy of NMJ structure following spaced stimulation shows that synaptic vesicle entry into nascent boutons occurs very early in the process, and that PKA and Synapsin are required for this process.
-
(2014)
J Neurosci
, vol.34
, pp. 10554-10563
-
-
Vasin, A.1
-
14
-
-
49649125106
-
Analysis of neuromuscular junctions: histology and in vivo imaging
-
14 Schmid, A., Sigrist, S.J., Analysis of neuromuscular junctions: histology and in vivo imaging. Methods Mol Biol 420 (2008), 239–251.
-
(2008)
Methods Mol Biol
, vol.420
, pp. 239-251
-
-
Schmid, A.1
Sigrist, S.J.2
-
15
-
-
69349095671
-
Glia and muscle sculpt neuromuscular arbors by engulfing destabilized synaptic boutons and shed presynaptic debris
-
15 Fuentes-Medel, Y., et al. Glia and muscle sculpt neuromuscular arbors by engulfing destabilized synaptic boutons and shed presynaptic debris. PLoS Biol, 7, 2009, e1000184.
-
(2009)
PLoS Biol
, vol.7
, pp. e1000184
-
-
Fuentes-Medel, Y.1
-
16
-
-
17444441559
-
Synaptic vesicles and pouches at the level of active zones of the neuromuscular junction
-
16 Couteaux, R., Pecot-Dechavassine, M., Synaptic vesicles and pouches at the level of active zones of the neuromuscular junction. C R Acad Sci Hebd Seances Acad Sci D 271 (1970), 2346–2349.
-
(1970)
C R Acad Sci Hebd Seances Acad Sci D
, vol.271
, pp. 2346-2349
-
-
Couteaux, R.1
Pecot-Dechavassine, M.2
-
17
-
-
0023736119
-
Membrane and cytoplasmic structure at synaptic junctions in the mammalian central nervous system
-
17 Landis, D.M., Membrane and cytoplasmic structure at synaptic junctions in the mammalian central nervous system. J Electron Microsc Tech 10 (1988), 129–151.
-
(1988)
J Electron Microsc Tech
, vol.10
, pp. 129-151
-
-
Landis, D.M.1
-
18
-
-
0037075207
-
wishful thinking encodes a BMP type II receptor that regulates synaptic growth in Drosophila
-
18 Aberle, H., et al. wishful thinking encodes a BMP type II receptor that regulates synaptic growth in Drosophila. Neuron 33 (2002), 545–558.
-
(2002)
Neuron
, vol.33
, pp. 545-558
-
-
Aberle, H.1
-
19
-
-
0036848075
-
The Drosophila Wnt: wingless, provides an essential signal for pre- and postsynaptic differentiation
-
19 Packard, M., et al. The Drosophila Wnt: wingless, provides an essential signal for pre- and postsynaptic differentiation. Cell 111 (2002), 319–330.
-
(2002)
Cell
, vol.111
, pp. 319-330
-
-
Packard, M.1
-
20
-
-
85027934678
-
Neurexins and neuroligins: recent insights from invertebrates
-
20 Knight, D., Xie, W., Boulianne, G.L., Neurexins and neuroligins: recent insights from invertebrates. Mol Neurobiol 44 (2011), 426–440.
-
(2011)
Mol Neurobiol
, vol.44
, pp. 426-440
-
-
Knight, D.1
Xie, W.2
Boulianne, G.L.3
-
21
-
-
84930616190
-
On the Teneurin track: a new synaptic organization molecule emerges
-
21 Mosca, T.J., On the Teneurin track: a new synaptic organization molecule emerges. Front Cell Neurosci, 9, 2015, 204.
-
(2015)
Front Cell Neurosci
, vol.9
, pp. 204
-
-
Mosca, T.J.1
-
22
-
-
0030273379
-
Genetic dissection of structural and functional components of synaptic plasticity. I. Fasciclin II controls synaptic stabilization and growth
-
22 Schuster, C.M., et al. Genetic dissection of structural and functional components of synaptic plasticity. I. Fasciclin II controls synaptic stabilization and growth. Neuron 17 (1996), 641–654.
-
(1996)
Neuron
, vol.17
, pp. 641-654
-
-
Schuster, C.M.1
-
23
-
-
80053922028
-
Extracellular matrix and its receptors in Drosophila neural development
-
23 Broadie, K., Baumgartner, S., Prokop, A., Extracellular matrix and its receptors in Drosophila neural development. Dev Neurobiol 71 (2011), 1102–1130.
-
(2011)
Dev Neurobiol
, vol.71
, pp. 1102-1130
-
-
Broadie, K.1
Baumgartner, S.2
Prokop, A.3
-
24
-
-
70349829157
-
Trans-synaptic transmission of vesicular Wnt signals through Evi/Wntless
-
24 Korkut, C., et al. Trans-synaptic transmission of vesicular Wnt signals through Evi/Wntless. Cell 139 (2009), 393–404.
-
(2009)
Cell
, vol.139
, pp. 393-404
-
-
Korkut, C.1
-
25
-
-
58149334854
-
Presynaptic local signaling by a canonical wingless pathway regulates development of the Drosophila neuromuscular junction
-
25 Miech, C., et al. Presynaptic local signaling by a canonical wingless pathway regulates development of the Drosophila neuromuscular junction. J Neurosci 28 (2008), 10875–10884.
-
(2008)
J Neurosci
, vol.28
, pp. 10875-10884
-
-
Miech, C.1
-
26
-
-
84906214368
-
Heterotrimeric Go protein links Wnt-Frizzled signaling with ankyrins to regulate the neuronal microtubule cytoskeleton
-
26 Luchtenborg, A.M., et al. Heterotrimeric Go protein links Wnt-Frizzled signaling with ankyrins to regulate the neuronal microtubule cytoskeleton. Development 141 (2014), 3399–3409.
-
(2014)
Development
, vol.141
, pp. 3399-3409
-
-
Luchtenborg, A.M.1
-
27
-
-
84894104048
-
Glial wingless/Wnt regulates glutamate receptor clustering and synaptic physiology at the Drosophila neuromuscular junction
-
27 Kerr, K.S., et al. Glial wingless/Wnt regulates glutamate receptor clustering and synaptic physiology at the Drosophila neuromuscular junction. J Neurosci 34 (2014), 2910–2920.
-
(2014)
J Neurosci
, vol.34
, pp. 2910-2920
-
-
Kerr, K.S.1
-
28
-
-
0035798238
-
The molecular biology of memory storage: a dialogue between genes and synapses
-
28 Kandel, E.R., The molecular biology of memory storage: a dialogue between genes and synapses. Science 294 (2001), 1030–1038.
-
(2001)
Science
, vol.294
, pp. 1030-1038
-
-
Kandel, E.R.1
-
29
-
-
84959885516
-
Phosphorylation of complexin by PKA regulates activity-dependent spontaneous neurotransmitter release and structural synaptic plasticity
-
29 Cho, R.W., et al. Phosphorylation of complexin by PKA regulates activity-dependent spontaneous neurotransmitter release and structural synaptic plasticity. Neuron 88 (2015), 749–761.
-
(2015)
Neuron
, vol.88
, pp. 749-761
-
-
Cho, R.W.1
-
30
-
-
84994709509
-
cAMP signals in Drosophila motor neurons are confined to single synaptic boutons
-
30 Maiellaro, I., et al. cAMP signals in Drosophila motor neurons are confined to single synaptic boutons. Cell Rep 17 (2016), 1238–1246.
-
(2016)
Cell Rep
, vol.17
, pp. 1238-1246
-
-
Maiellaro, I.1
-
31
-
-
85016765114
-
Cyclic nucleotide signaling is required during synaptic refinement at the Drosophila neuromuscular junction
-
31 Vonhoff, F., Keshishian, H., Cyclic nucleotide signaling is required during synaptic refinement at the Drosophila neuromuscular junction. Dev Neurobiol, 2016.
-
(2016)
Dev Neurobiol
-
-
Vonhoff, F.1
Keshishian, H.2
-
32
-
-
0033529567
-
Regulation of DLG localization at synapses by CaMKII-dependent phosphorylation
-
32 Koh, Y.H., et al. Regulation of DLG localization at synapses by CaMKII-dependent phosphorylation. Cell 98 (1999), 353–363.
-
(1999)
Cell
, vol.98
, pp. 353-363
-
-
Koh, Y.H.1
-
33
-
-
84983548634
-
Presynaptic CamKII regulates activity-dependent axon terminal growth
-
33 Nesler, K.R., et al. Presynaptic CamKII regulates activity-dependent axon terminal growth. Mol Cell Neurosci 76 (2016), 33–41.
-
(2016)
Mol Cell Neurosci
, vol.76
, pp. 33-41
-
-
Nesler, K.R.1
-
34
-
-
0033568865
-
2+/calmodulin-dependent protein Kinase II via dendritic protein synthesis in hippocampal neurons
-
2+/calmodulin-dependent protein Kinase II via dendritic protein synthesis in hippocampal neurons. J Neurosci 19 (1999), 7823–7833.
-
(1999)
J Neurosci
, vol.19
, pp. 7823-7833
-
-
Ouyang, Y.1
-
35
-
-
30344449514
-
Synaptic protein synthesis associated with memory is regulated by the RISC pathway in Drosophila
-
35 Ashraf, S.I., et al. Synaptic protein synthesis associated with memory is regulated by the RISC pathway in Drosophila. Cell 124 (2006), 191–205.
-
(2006)
Cell
, vol.124
, pp. 191-205
-
-
Ashraf, S.I.1
-
36
-
-
84879742663
-
The miRNA pathway controls rapid changes in activity-dependent synaptic structure at the Drosophila melanogaster neuromuscular junction
-
36 Nesler, K.R., et al. The miRNA pathway controls rapid changes in activity-dependent synaptic structure at the Drosophila melanogaster neuromuscular junction. PLoS One, 8, 2013, e68385.
-
(2013)
PLoS One
, vol.8
, pp. e68385
-
-
Nesler, K.R.1
-
37
-
-
84936748232
-
The translational regulator Cup controls NMJ presynaptic terminal morphology
-
37 Menon, K.P., Carrillo, R.A., Zinn, K., The translational regulator Cup controls NMJ presynaptic terminal morphology. Mol Cell Neurosci 67 (2015), 126–136.
-
(2015)
Mol Cell Neurosci
, vol.67
, pp. 126-136
-
-
Menon, K.P.1
Carrillo, R.A.2
Zinn, K.3
-
38
-
-
23944519706
-
LIM Kinase 1 controls synaptic stability downstream of the type II BMP receptor
-
38 Eaton, B.A., Davis, G.W., LIM Kinase 1 controls synaptic stability downstream of the type II BMP receptor. Neuron 47 (2005), 695–708.
-
(2005)
Neuron
, vol.47
, pp. 695-708
-
-
Eaton, B.A.1
Davis, G.W.2
-
39
-
-
77953260849
-
Retrograde BMP signaling controls synaptic growth at the NMJ by regulating trio expression in motor neurons
-
39 Ball, R.W., et al. Retrograde BMP signaling controls synaptic growth at the NMJ by regulating trio expression in motor neurons. Neuron 66 (2010), 536–549.
-
(2010)
Neuron
, vol.66
, pp. 536-549
-
-
Ball, R.W.1
-
40
-
-
84887034082
-
Retrograde BMP signaling at the synapse: a permissive signal for synapse maturation and activity-dependent plasticity
-
40 Berke, B., et al. Retrograde BMP signaling at the synapse: a permissive signal for synapse maturation and activity-dependent plasticity. J Neurosci 33 (2013), 17937–17950.
-
(2013)
J Neurosci
, vol.33
, pp. 17937-17950
-
-
Berke, B.1
-
41
-
-
84918590276
-
Crimpy enables discrimination of presynaptic and postsynaptic pools of a BMP at the Drosophila neuromuscular junction
-
Analysis of the Gbb-associated protein Crimpy reveals that this factor is co-released with a specialized pool of Gbb from presynaptic terminals whose function appears to be distinct from retrograde Gbb signaling from the postsynaptic muscle source.
-
41•• James, R.E., et al. Crimpy enables discrimination of presynaptic and postsynaptic pools of a BMP at the Drosophila neuromuscular junction. Dev Cell 31 (2014), 586–598 Analysis of the Gbb-associated protein Crimpy reveals that this factor is co-released with a specialized pool of Gbb from presynaptic terminals whose function appears to be distinct from retrograde Gbb signaling from the postsynaptic muscle source.
-
(2014)
Dev Cell
, vol.31
, pp. 586-598
-
-
James, R.E.1
-
42
-
-
84891516104
-
Postsynaptic glutamate receptors regulate local BMP signaling at the Drosophila neuromuscular junction
-
Detailed analysis of BMP signaling during the maturation of synaptic sites at the NMJ suggests that postsynaptic receptors themselves regulate a Wit and Mad-dependent local signaling to mediate the exchange of GluR subunits.
-
42• Sulkowski, M., Kim, Y.J., Serpe, M., Postsynaptic glutamate receptors regulate local BMP signaling at the Drosophila neuromuscular junction. Development 141 (2014), 436–447 Detailed analysis of BMP signaling during the maturation of synaptic sites at the NMJ suggests that postsynaptic receptors themselves regulate a Wit and Mad-dependent local signaling to mediate the exchange of GluR subunits.
-
(2014)
Development
, vol.141
, pp. 436-447
-
-
Sulkowski, M.1
Kim, Y.J.2
Serpe, M.3
-
43
-
-
84867401472
-
Integration of a retrograde signal during synapse formation by glia-secreted TGF-beta ligand
-
43 Fuentes-Medel, Y., et al. Integration of a retrograde signal during synapse formation by glia-secreted TGF-beta ligand. Curr Biol 22 (2012), 1831–1838.
-
(2012)
Curr Biol
, vol.22
, pp. 1831-1838
-
-
Fuentes-Medel, Y.1
-
44
-
-
84979538992
-
Syncrip/hnRNP Q influences synaptic transmission and regulates BMP signaling at the Drosophila neuromuscular synapse
-
44 Halstead, J.M., et al. Syncrip/hnRNP Q influences synaptic transmission and regulates BMP signaling at the Drosophila neuromuscular synapse. Biol Open 3 (2014), 839–849.
-
(2014)
Biol Open
, vol.3
, pp. 839-849
-
-
Halstead, J.M.1
-
45
-
-
84973512776
-
Augmented noncanonical BMP tyle II receptor signaling mediates the synaptic abnormality of fragile X syndrome
-
45 Kashima, R., et al. Augmented noncanonical BMP tyle II receptor signaling mediates the synaptic abnormality of fragile X syndrome. Sci Signal, 9, 2016, ra58.
-
(2016)
Sci Signal
, vol.9
, pp. ra58
-
-
Kashima, R.1
-
46
-
-
84950297406
-
Control of synaptic connectivity by a network of Drosophila IgSF cell surface proteins
-
Pioneering work on members of the Dpr and DIP receptor families during neuromuscular development reveals phenotypic signatures and genetic interactions indicative of a functional role in BMP signaling require for larval NMJ expansion.
-
46•• Carrillo, R.A., et al. Control of synaptic connectivity by a network of Drosophila IgSF cell surface proteins. Cell 163 (2015), 1770–1782 Pioneering work on members of the Dpr and DIP receptor families during neuromuscular development reveals phenotypic signatures and genetic interactions indicative of a functional role in BMP signaling require for larval NMJ expansion.
-
(2015)
Cell
, vol.163
, pp. 1770-1782
-
-
Carrillo, R.A.1
-
47
-
-
84974569646
-
Angelman syndrome protein Ube3a regulates synaptic growth and endocytosis by inhibiting BMP signaling in Drosophila
-
47 Li, W., et al. Angelman syndrome protein Ube3a regulates synaptic growth and endocytosis by inhibiting BMP signaling in Drosophila. PLoS Genet, 12, 2016, e1006062.
-
(2016)
PLoS Genet
, vol.12
, pp. e1006062
-
-
Li, W.1
-
48
-
-
84926199468
-
Drosophila S6 Kinase like inhibits neuromuscular junction growth by downregulating the BMP receptor thickveins
-
48 Zhao, G., et al. Drosophila S6 Kinase like inhibits neuromuscular junction growth by downregulating the BMP receptor thickveins. PLoS Genet, 11, 2015, e1004984.
-
(2015)
PLoS Genet
, vol.11
, pp. e1004984
-
-
Zhao, G.1
-
49
-
-
84995477424
-
MAN1 restricts BMP signaling during synaptic growth in Drosophila
-
49 Laugks, U., Hieke, M., Wagner, N., MAN1 restricts BMP signaling during synaptic growth in Drosophila. Cell Mol Neurobiol, 2016.
-
(2016)
Cell Mol Neurobiol
-
-
Laugks, U.1
Hieke, M.2
Wagner, N.3
-
50
-
-
27644593348
-
Retrograde signaling by Syt 4 induces presynaptic release and synapse-specific growth
-
50 Yoshihara, M., et al. Retrograde signaling by Syt 4 induces presynaptic release and synapse-specific growth. Science 310 (2005), 858–863.
-
(2005)
Science
, vol.310
, pp. 858-863
-
-
Yoshihara, M.1
-
51
-
-
84875495379
-
Regulation of postsynaptic retrograde signaling by presynaptic exosome release
-
51 Korkut, C., et al. Regulation of postsynaptic retrograde signaling by presynaptic exosome release. Neuron 77 (2013), 1039–1046.
-
(2013)
Neuron
, vol.77
, pp. 1039-1046
-
-
Korkut, C.1
-
52
-
-
84971657694
-
The postsynaptic t-SNARE Syntaxin 4 controls traffic of Neuroligin 1 and Synaptotagmin 4 to regulate retrograde signaling
-
52 Harris, K.P., et al. The postsynaptic t-SNARE Syntaxin 4 controls traffic of Neuroligin 1 and Synaptotagmin 4 to regulate retrograde signaling. Elife, 5, 2016.
-
(2016)
Elife
, vol.5
-
-
Harris, K.P.1
-
53
-
-
77953658943
-
Drosophila neuroligin 1 promotes growth and postsynaptic differentiation at glutamatergic neuromuscular junctions
-
53 Banovic, D., et al. Drosophila neuroligin 1 promotes growth and postsynaptic differentiation at glutamatergic neuromuscular junctions. Neuron 66 (2010), 724–738.
-
(2010)
Neuron
, vol.66
, pp. 724-738
-
-
Banovic, D.1
-
54
-
-
84884419438
-
LAR-RPTPs: synaptic adhesion molecules that shape synapse development
-
54 Um, J.W., Ko, J., LAR-RPTPs: synaptic adhesion molecules that shape synapse development. Trends Cell Biol 23 (2013), 465–475.
-
(2013)
Trends Cell Biol
, vol.23
, pp. 465-475
-
-
Um, J.W.1
Ko, J.2
-
55
-
-
84866065861
-
Cooperation of Syd-1 with Neurexin synchronizes pre- with postsynaptic assembly
-
A key study linking Neurexin function with the establishment of active zones at the NMJ.
-
55• Owald, D., et al. Cooperation of Syd-1 with Neurexin synchronizes pre- with postsynaptic assembly. Nat Neurosci 15 (2012), 1219–1226 A key study linking Neurexin function with the establishment of active zones at the NMJ.
-
(2012)
Nat Neurosci
, vol.15
, pp. 1219-1226
-
-
Owald, D.1
-
56
-
-
84901614648
-
Composition of isolated synaptic boutons reveals the amounts of vesicle trafficking proteins
-
A tour de force characterization of synaptic protein composition demonstrates the complexity and relative expression of the many factors that reside in these synaptic varicosities.
-
56•• Wilhelm, B.G., et al. Composition of isolated synaptic boutons reveals the amounts of vesicle trafficking proteins. Science 344 (2014), 1023–1028 A tour de force characterization of synaptic protein composition demonstrates the complexity and relative expression of the many factors that reside in these synaptic varicosities.
-
(2014)
Science
, vol.344
, pp. 1023-1028
-
-
Wilhelm, B.G.1
-
57
-
-
84863826404
-
The presynaptic active zone
-
57 Sudhof, T.C., The presynaptic active zone. Neuron 75 (2012), 11–25.
-
(2012)
Neuron
, vol.75
, pp. 11-25
-
-
Sudhof, T.C.1
-
59
-
-
84975487872
-
Role of Bassoon and Piccolo in assembly and molecular organization of the active zone
-
59 Gundelfinger, E.D., Reissner, C., Garner, C.C., Role of Bassoon and Piccolo in assembly and molecular organization of the active zone. Front Synaptic Neurosci, 7, 2015, 19.
-
(2015)
Front Synaptic Neurosci
, vol.7
, pp. 19
-
-
Gundelfinger, E.D.1
Reissner, C.2
Garner, C.C.3
-
60
-
-
83755169214
-
RIM-binding protein: a central part of the active zone, is essential for neurotransmitter release
-
60 Liu, K.S., et al. RIM-binding protein: a central part of the active zone, is essential for neurotransmitter release. Science 334 (2011), 1565–1569.
-
(2011)
Science
, vol.334
, pp. 1565-1569
-
-
Liu, K.S.1
-
61
-
-
33646724067
-
2+ channel clustering, and vesicle release
-
2+ channel clustering, and vesicle release. Science 312 (2006), 1051–1054.
-
(2006)
Science
, vol.312
, pp. 1051-1054
-
-
Kittel, R.J.1
-
62
-
-
84942134033
-
RIM-BPs mediate tight coupling of action potentials to Ca(2+)-triggered neurotransmitter release
-
First genetic study analyzing the active zone function of Rim-BPs in mice.
-
62• Acuna, C., et al. RIM-BPs mediate tight coupling of action potentials to Ca(2+)-triggered neurotransmitter release. Neuron 87 (2015), 1234–1247 First genetic study analyzing the active zone function of Rim-BPs in mice.
-
(2015)
Neuron
, vol.87
, pp. 1234-1247
-
-
Acuna, C.1
-
63
-
-
84991059218
-
How to make an active zone: unexpected universal functional redundancy between RIMs and RIM-BPs
-
Consistent with previous analysis of Drosophila Rim-BPs, Rim-BPs are shown to execute an important function in AZ assembly together and functionally overlapping with RIM family proteins.
-
63•• Acuna, C., Liu, X., Sudhof, T.C., How to make an active zone: unexpected universal functional redundancy between RIMs and RIM-BPs. Neuron 91 (2016), 792–807 Consistent with previous analysis of Drosophila Rim-BPs, Rim-BPs are shown to execute an important function in AZ assembly together and functionally overlapping with RIM family proteins.
-
(2016)
Neuron
, vol.91
, pp. 792-807
-
-
Acuna, C.1
Liu, X.2
Sudhof, T.C.3
-
64
-
-
84991108519
-
Fusion competent synaptic vesicles persist upon active zone disruption and loss of vesicle docking
-
Analyzes mice lacking RIM and ELKS, whose AZs consequently loose Munc13, Bassoon, Piccolo, and RIM-BP as well. While ultrastructural analysis indicates a severe disassembly of the active zone, some SV release remains.
-
64•• Wang, S.S., et al. Fusion competent synaptic vesicles persist upon active zone disruption and loss of vesicle docking. Neuron 91 (2016), 777–791 Analyzes mice lacking RIM and ELKS, whose AZs consequently loose Munc13, Bassoon, Piccolo, and RIM-BP as well. While ultrastructural analysis indicates a severe disassembly of the active zone, some SV release remains.
-
(2016)
Neuron
, vol.91
, pp. 777-791
-
-
Wang, S.S.1
-
65
-
-
84982166075
-
2+ channel-vesicle coupling
-
Shows that two independent SV release components can co-exist within a single active zone via two differentially positioned Unc13 isoforms. Isoform-specific Unc13-AZ scaffold interactions regulate SV-Ca(2+)-channel topology which tightens during development to optimize synaptic transmission.
-
2+ channel-vesicle coupling. Nat Neurosci, 2016 Shows that two independent SV release components can co-exist within a single active zone via two differentially positioned Unc13 isoforms. Isoform-specific Unc13-AZ scaffold interactions regulate SV-Ca(2+)-channel topology which tightens during development to optimize synaptic transmission.
-
(2016)
Nat Neurosci
-
-
Bohme, M.A.1
-
66
-
-
84959013884
-
Presynaptic spinophilin tunes neurexin signalling to control active zone architecture and function
-
Demonstrates that different PDZ-domain proteins compete for Neurexin and thereby tune the assembly of the AZ matrix.
-
66•• Muhammad, K., et al. Presynaptic spinophilin tunes neurexin signalling to control active zone architecture and function. Nat Commun, 6, 2015, p8362 Demonstrates that different PDZ-domain proteins compete for Neurexin and thereby tune the assembly of the AZ matrix.
-
(2015)
Nat Commun
, vol.6
, pp. p8362
-
-
Muhammad, K.1
-
67
-
-
79953200774
-
Optical quantal analysis of synaptic transmission in wild-type and rab3-mutant Drosophila motor axons
-
67 Peled, E.S., Isacoff, E.Y., Optical quantal analysis of synaptic transmission in wild-type and rab3-mutant Drosophila motor axons. Nat Neurosci 14 (2011), 519–526.
-
(2011)
Nat Neurosci
, vol.14
, pp. 519-526
-
-
Peled, E.S.1
Isacoff, E.Y.2
-
68
-
-
84895560356
-
Evoked and spontaneous transmission favored by distinct sets of synapses
-
68 Peled, E.S., Newman, Z.L., Isacoff, E.Y., Evoked and spontaneous transmission favored by distinct sets of synapses. Curr Biol 24 (2014), 484–493.
-
(2014)
Curr Biol
, vol.24
, pp. 484-493
-
-
Peled, E.S.1
Newman, Z.L.2
Isacoff, E.Y.3
-
69
-
-
77952729399
-
Rapid structural alterations of the active zone lead to sustained changes in neurotransmitter release
-
69 Matz, J., et al. Rapid structural alterations of the active zone lead to sustained changes in neurotransmitter release. Proc Natl Acad Sci U S A 107 (2010), 8836–8841.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 8836-8841
-
-
Matz, J.1
-
70
-
-
84862860810
-
Release probability of hippocampal glutamatergic terminals scales with the size of the active zone
-
70 Holderith, N., et al. Release probability of hippocampal glutamatergic terminals scales with the size of the active zone. Nat Neurosci 15 (2012), 988–997.
-
(2012)
Nat Neurosci
, vol.15
, pp. 988-997
-
-
Holderith, N.1
-
71
-
-
84867295592
-
Molecular machines governing exocytosis of synaptic vesicles
-
71 Jahn, R., Fasshauer, D., Molecular machines governing exocytosis of synaptic vesicles. Nature 490 (2012), 201–207.
-
(2012)
Nature
, vol.490
, pp. 201-207
-
-
Jahn, R.1
Fasshauer, D.2
-
72
-
-
84908246400
-
The morphological and molecular nature of synaptic vesicle priming at presynaptic active zones
-
72 Imig, C., et al. The morphological and molecular nature of synaptic vesicle priming at presynaptic active zones. Neuron 84 (2014), 416–431.
-
(2014)
Neuron
, vol.84
, pp. 416-431
-
-
Imig, C.1
-
73
-
-
76349098018
-
Synaptobrevin N-terminally bound to syntaxin-SNAP-25 defines the primed vesicle state in regulated exocytosis
-
73 Walter, A.M., et al. Synaptobrevin N-terminally bound to syntaxin-SNAP-25 defines the primed vesicle state in regulated exocytosis. J Cell Biol 188 (2010), 401–413.
-
(2010)
J Cell Biol
, vol.188
, pp. 401-413
-
-
Walter, A.M.1
-
74
-
-
85027945821
-
Munc13 mediates the transition from the closed syntaxin-Munc18 complex to the SNARE complex
-
74 Ma, C., et al. Munc13 mediates the transition from the closed syntaxin-Munc18 complex to the SNARE complex. Nat Struct Mol Biol 18 (2011), 542–549.
-
(2011)
Nat Struct Mol Biol
, vol.18
, pp. 542-549
-
-
Ma, C.1
-
75
-
-
84957928455
-
Identification of a Munc 13-sensitive step in chromaffin cell large dense-core vesicle exocytosis
-
Provides interesting mechanistic details comparing fusion processes of dense-core vesicle with exocytosis of regular synaptic vesicles.
-
75• Man, K.M., et al. Identification of a Munc 13-sensitive step in chromaffin cell large dense-core vesicle exocytosis. Elife, 2015, 4 Provides interesting mechanistic details comparing fusion processes of dense-core vesicle with exocytosis of regular synaptic vesicles.
-
(2015)
Elife
, pp. 4
-
-
Man, K.M.1
-
76
-
-
0037172972
-
Total arrest of spontaneous and evoked synaptic transmission but normal synaptogenesis in the absence of Munc13-mediated vesicle priming
-
76 Varoqueaux, F., et al. Total arrest of spontaneous and evoked synaptic transmission but normal synaptogenesis in the absence of Munc13-mediated vesicle priming. Proc Natl Acad Sci U S A 99 (2002), 9037–9042.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 9037-9042
-
-
Varoqueaux, F.1
-
77
-
-
84880039882
-
Dynamic control of synaptic vesicle replenishment and short-term plasticity by Ca(2+)-calmodulin-Munc13-1 signaling
-
77 Lipstein, N., et al. Dynamic control of synaptic vesicle replenishment and short-term plasticity by Ca(2+)-calmodulin-Munc13-1 signaling. Neuron 79 (2013), 82–96.
-
(2013)
Neuron
, vol.79
, pp. 82-96
-
-
Lipstein, N.1
-
78
-
-
84055189415
-
Nanodomain coupling between Ca(2)(+) channels and sensors of exocytosis at fast mammalian synapses
-
78 Eggermann, E., et al. Nanodomain coupling between Ca(2)(+) channels and sensors of exocytosis at fast mammalian synapses. Nat Rev Neurosci 13 (2012), 7–21.
-
(2012)
Nat Rev Neurosci
, vol.13
, pp. 7-21
-
-
Eggermann, E.1
-
79
-
-
84883814255
-
Superpriming of synaptic vesicles after their recruitment to the readily releasable pool
-
79 Lee, J.S., et al. Superpriming of synaptic vesicles after their recruitment to the readily releasable pool. Proc Natl Acad Sci U S A 110 (2013), 15079–15084.
-
(2013)
Proc Natl Acad Sci U S A
, vol.110
, pp. 15079-15084
-
-
Lee, J.S.1
-
80
-
-
33846785411
-
2+ channels determines fast neurotransmitter release
-
2+ channels determines fast neurotransmitter release. Neuron 53 (2007), 563–575.
-
(2007)
Neuron
, vol.53
, pp. 563-575
-
-
Wadel, K.1
Neher, E.2
Sakaba, T.3
-
81
-
-
78651509693
-
2+ channels to presynaptic active zones via a direct PDZ-domain interaction
-
2+ channels to presynaptic active zones via a direct PDZ-domain interaction. Cell 144 (2011), 282–295.
-
(2011)
Cell
, vol.144
, pp. 282-295
-
-
Kaeser, P.S.1
-
82
-
-
78651481610
-
RIM determines Ca(2)+ channel density and vesicle docking at the presynaptic active zone
-
82 Han, Y., et al. RIM determines Ca(2)+ channel density and vesicle docking at the presynaptic active zone. Neuron 69 (2011), 304–316.
-
(2011)
Neuron
, vol.69
, pp. 304-316
-
-
Han, Y.1
-
83
-
-
84985994308
-
Presynaptic DLG regulates synaptic function through the localization of voltage-activated Ca(2+) Channels
-
83 Astorga, C., et al. Presynaptic DLG regulates synaptic function through the localization of voltage-activated Ca(2+) Channels. Sci Rep, 6, 2016, 32132.
-
(2016)
Sci Rep
, vol.6
, pp. 32132
-
-
Astorga, C.1
-
84
-
-
67650470999
-
Maturation of active zone assembly by Drosophila Bruchpilot
-
84 Fouquet, W., et al. Maturation of active zone assembly by Drosophila Bruchpilot. J Cell Biol 186 (2009), 129–145.
-
(2009)
J Cell Biol
, vol.186
, pp. 129-145
-
-
Fouquet, W.1
-
85
-
-
84880000317
-
Liprin-alpha2 promotes the presynaptic recruitment and turnover of RIM1/CASK to facilitate synaptic transmission
-
85 Spangler, S.A., et al. Liprin-alpha2 promotes the presynaptic recruitment and turnover of RIM1/CASK to facilitate synaptic transmission. J Cell Biol 201 (2013), 915–928.
-
(2013)
J Cell Biol
, vol.201
, pp. 915-928
-
-
Spangler, S.A.1
-
86
-
-
0033598333
-
The liprin protein SYD-2 regulates the differentiation of presynaptic termini in C. elegans
-
86 Zhen, M., Jin, Y., The liprin protein SYD-2 regulates the differentiation of presynaptic termini in C. elegans. Nature 401 (1999), 371–375.
-
(1999)
Nature
, vol.401
, pp. 371-375
-
-
Zhen, M.1
Jin, Y.2
-
87
-
-
77149135790
-
A Syd-1 homologue regulates pre- and postsynaptic maturation in Drosophila
-
87 Owald, D., et al. A Syd-1 homologue regulates pre- and postsynaptic maturation in Drosophila. J Cell Biol 188 (2010), 565–579.
-
(2010)
J Cell Biol
, vol.188
, pp. 565-579
-
-
Owald, D.1
-
88
-
-
84884238345
-
The Bruchpilot cytomatrix determines the size of the readily releasable pool of synaptic vesicles
-
88 Matkovic, T., et al. The Bruchpilot cytomatrix determines the size of the readily releasable pool of synaptic vesicles. J Cell Biol 202 (2013), 667–683.
-
(2013)
J Cell Biol
, vol.202
, pp. 667-683
-
-
Matkovic, T.1
-
89
-
-
84978792169
-
ELKS controls the pool of readily releasable vesicles at excitatory synapses through its N-terminal coiled-coil domains
-
89 Held, R.G., Liu, C., Kaeser, P.S., ELKS controls the pool of readily releasable vesicles at excitatory synapses through its N-terminal coiled-coil domains. Elife, 5, 2016.
-
(2016)
Elife
, vol.5
-
-
Held, R.G.1
Liu, C.2
Kaeser, P.S.3
-
90
-
-
84890819665
-
Liprin-alpha/SYD-2 determines the size of dense projections in presynaptic active zones in C. elegans
-
90 Kittelmann, M., et al. Liprin-alpha/SYD-2 determines the size of dense projections in presynaptic active zones in C. elegans. J Cell Biol 203 (2013), 849–863.
-
(2013)
J Cell Biol
, vol.203
, pp. 849-863
-
-
Kittelmann, M.1
-
91
-
-
84922154929
-
Super-resolution microscopy of the synaptic active zone
-
91 Ehmann, N., Sauer, M., Kittel, R.J., Super-resolution microscopy of the synaptic active zone. Front Cell Neurosci, 9, 2015, p. 7.
-
(2015)
Front Cell Neurosci
, vol.9
, pp. p. 7
-
-
Ehmann, N.1
Sauer, M.2
Kittel, R.J.3
-
92
-
-
79951948881
-
Protein scaffolds in the coupling of synaptic exocytosis and endocytosis
-
92 Haucke, V., Neher, E., Sigrist, S.J., Protein scaffolds in the coupling of synaptic exocytosis and endocytosis. Nat Rev Neurosci 12 (2011), 127–138.
-
(2011)
Nat Rev Neurosci
, vol.12
, pp. 127-138
-
-
Haucke, V.1
Neher, E.2
Sigrist, S.J.3
-
93
-
-
84961282260
-
A network of three types of filaments organizes synaptic vesicles for storage mobilization, and docking
-
93 Cole, A.A., Chen, X., Reese, T.S., A network of three types of filaments organizes synaptic vesicles for storage mobilization, and docking. J Neurosci 36 (2016), 3222–3230.
-
(2016)
J Neurosci
, vol.36
, pp. 3222-3230
-
-
Cole, A.A.1
Chen, X.2
Reese, T.S.3
-
94
-
-
78049340976
-
Naked dense bodies provoke depression
-
94 Hallermann, S., et al. Naked dense bodies provoke depression. J Neurosci 30 (2010), 14340–14345.
-
(2010)
J Neurosci
, vol.30
, pp. 14340-14345
-
-
Hallermann, S.1
-
95
-
-
84961934910
-
Nanoscale dynamics of synaptic vesicle trafficking and fusion at the presynaptic active zone
-
95 Vaithianathan, T., et al. Nanoscale dynamics of synaptic vesicle trafficking and fusion at the presynaptic active zone. Elife, 5, 2016.
-
(2016)
Elife
, vol.5
-
-
Vaithianathan, T.1
-
96
-
-
85008683526
-
Fife organizes synaptic vesicles and calcium channels for high-probability neurotransmitter release
-
Uses super-resolution imaging to track single vesicles at voltage-clamped presynaptic terminals containing large ribbon-type active zone cytomatrices. SVs are found to diffuse along ribbons.
-
96• Bruckner, J.J., et al. Fife organizes synaptic vesicles and calcium channels for high-probability neurotransmitter release. J Cell Biol 216 (2016), 231–246 Uses super-resolution imaging to track single vesicles at voltage-clamped presynaptic terminals containing large ribbon-type active zone cytomatrices. SVs are found to diffuse along ribbons.
-
(2016)
J Cell Biol
, vol.216
, pp. 231-246
-
-
Bruckner, J.J.1
-
97
-
-
79955784858
-
Rapid active zone remodeling during synaptic plasticity
-
97 Weyhersmuller, A., et al. Rapid active zone remodeling during synaptic plasticity. J Neurosci 31 (2011), 6041–6052.
-
(2011)
J Neurosci
, vol.31
, pp. 6041-6052
-
-
Weyhersmuller, A.1
-
98
-
-
84907319813
-
Quantitative super-resolution imaging of Bruchpilot distinguishes active zone states
-
98 Ehmann, N., et al. Quantitative super-resolution imaging of Bruchpilot distinguishes active zone states. Nat Commun, 5, 2014, 4650.
-
(2014)
Nat Commun
, vol.5
, pp. 4650
-
-
Ehmann, N.1
-
99
-
-
84923221448
-
Bruchpilot and Synaptotagmin collaborate to drive rapid glutamate release and active zone differentiation
-
99 Paul, M.M., et al. Bruchpilot and Synaptotagmin collaborate to drive rapid glutamate release and active zone differentiation. Front Cell Neurosci, 9, 2015, 29.
-
(2015)
Front Cell Neurosci
, vol.9
, pp. 29
-
-
Paul, M.M.1
-
100
-
-
84928980796
-
Molecular remodeling of the presynaptic active zone of Drosophila photoreceptors via activity-dependent feedback
-
100 Sugie, A., et al. Molecular remodeling of the presynaptic active zone of Drosophila photoreceptors via activity-dependent feedback. Neuron 86 (2015), 711–725.
-
(2015)
Neuron
, vol.86
, pp. 711-725
-
-
Sugie, A.1
-
101
-
-
71149094853
-
Rab3 dynamically controls protein composition at active zones
-
101 Graf, E.R., et al. Rab3 dynamically controls protein composition at active zones. Neuron 64 (2009), 663–677.
-
(2009)
Neuron
, vol.64
, pp. 663-677
-
-
Graf, E.R.1
-
102
-
-
84943329366
-
Mutational analysis of Rab3 function for controlling active zone protein composition at the Drosophila neuromuscular junction
-
102 Chen, S., et al. Mutational analysis of Rab3 function for controlling active zone protein composition at the Drosophila neuromuscular junction. PLoS One, 10, 2015, e0136938.
-
(2015)
PLoS One
, vol.10
, pp. e0136938
-
-
Chen, S.1
-
103
-
-
85019538558
-
RabGEF controls active zone development at the Drosophila neuromuscular junction
-
103 Bae, H., et al. RabGEF controls active zone development at the Drosophila neuromuscular junction. eNeuro, 3, 2016.
-
(2016)
eNeuro
, vol.3
-
-
Bae, H.1
-
104
-
-
84988650182
-
The Drosophila KIF1A homolog unc-104 is important for site-specific synapse maturation
-
104 Zhang, Y.V., et al. The Drosophila KIF1A homolog unc-104 is important for site-specific synapse maturation. Front Cell Neurosci, 10, 2016, 207.
-
(2016)
Front Cell Neurosci
, vol.10
, pp. 207
-
-
Zhang, Y.V.1
-
105
-
-
85008343659
-
In vivo single-molecule imaging of syntaxin1A reveals polyphosphoinositide- and activity-dependent trapping in presynaptic nanoclusters
-
105 Bademosi, A.T., et al. In vivo single-molecule imaging of syntaxin1A reveals polyphosphoinositide- and activity-dependent trapping in presynaptic nanoclusters. Nat Commun, 8, 2017, 13660.
-
(2017)
Nat Commun
, vol.8
, pp. 13660
-
-
Bademosi, A.T.1
|