Endolichenic Fungi: A Hidden Reservoir of Next Generation Biopharmaceuticals

Trends in Biotechnology

Volumn 35, Issue 9, 2017, Pages 808-813

  Singh, Brahma N ^a   Upreti, Dalip K ^a   Gupta, Vijai K ^b   Dai, Xiao Feng ^c   Jiang, Yueming ^d  

^a CSIR NATIONAL BOTANICAL RESEARCH INSTITUTE   (India)

^b TALLINN UNIVERSITY OF TECHNOLOGY   (Estonia)

^c INSTITUTE OF PLANT PROTECTION   (China)

^d SOUTH CHINA INSTITUTE OF BOTANY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BIOPHARMACEUTICAL DEVELOPMENT; BIOPHARMACEUTICALS; BIORESOURCES; CHEMICAL DIVERSITY; STRUCTURAL CLASS;

FUNGI;

BIOPROSPECTING; BIOTECHNOLOGY; ENDOLICHENIC FUNGI; FUNGUS; HUMAN; METABOLITE; METABOLOMICS; MICROBIAL DIVERSITY; NONHUMAN; PRIORITY JOURNAL; SHORT SURVEY; CHEMISTRY; DRUG DEVELOPMENT; LICHEN (ORGANISM); PHARMACEUTICS;

BIOPHARMACEUTICS; DRUG DISCOVERY; LICHENS;

EID: 85016748091     PISSN: 01677799     EISSN: 18793096     Source Type: Journal    
DOI: 10.1016/j.tibtech.2017.03.003     Document Type: Short Survey

References (15)

1. Lutzoni, F., Miadlikowska, J., Lichens. Curr. Biol. 19 (2009), R502–R503.
2. Divakar, P.K., et al. Evolution of complex symbiotic relationships in a morphologically derived family of lichen-forming fungi. New Phytol. 208 (2015), 1217–1226.
3. Kellogg, J.J., Raja, H.A., Endolichenic fungi: a new source of rich bioactive secondary metabolites on the horizon. Phytochem. Rev., 2016, 10.1007/s11101-016-9473-1 Published online July 12, 2016.
4. U'ren, J.M., et al. Community analysis reveals close affinities between endophytic and endolichenic fungi in mosses and lichens. Microb. Ecol. 60 (2010), 340–353.
5. Nisa, H., et al. Fungal endophytes as prolific source of phytochemicals and other bioactive natural products: a review. Microb. Pathogen. 82 (2015), 50–59.
6. Paranagama, P.A., et al. Bioactive secondary metabolites from an endolichenic fungus, Corynespora sp inhabiting the cavern beard lichen, Usnea cavernosa. Planta Med. 74 (2008), 933–934.
7. Cheon, D.M., J.D, Kim, H.Y., Detection of antifungal endolichenic fungi and antifungal compound. Korean J. Microbiol. 4 (2013), 165–171.
8. Jiao, Y., et al. New metabolites from endolichenic fungus Pleosporales sp. Chem. Biodivers. 12 (2015), 1095–1104.
9. Li, X.B., et al. Identification and biological evaluation of secondary metabolites from the endolichenic fungus Aspergillus versicolor. Chem. Biodivers. 12 (2015), 575–592.
10. Xie, F., et al. Quinone derivatives isolated from the endolichenic fungus Phialocephala fortinii are Mdr1 modulators that combat azole resistance in Candida albicans. Sci. Rep., 6, 2016, 33687.
11. Skirycz, A., et al. Medicinal bioprospecting of the Amazon rainforest: a modern Eldorado?. Trends Biotechnol. 34 (2016), 781–790.
12. Kueger, S., et al. High-resolution plant metabolomics: from mass spectral features to metabolites and from whole-cell analysis to subcellular metabolite distributions. Plant J. 70 (2012), 39–50.
13. Hulce, J.J., et al. Proteome-wide mapping of cholesterol-interacting proteins in mammalian cells. Nat. Methods 10 (2013), 259–264.
14. Wang, Q.X., et al. Ophiobolins P-T, five new cytotoxic and antibacterial sesterterpenes from the endolichenic fungus Ulocladium sp. Fitoterapia 90 (2013), 220–227.
15. Ro, D.K., et al. Production of the antimalarial drug precursor artemisinic acid in engineered yeast. Nature 440 (2006), 940–943.