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Volumn 6, Issue 7, 2016, Pages

An open-label phase I dose-finding study of APR-246 in hematological malignancies

Author keywords

[No Author keywords available]

Indexed keywords

2-HYDROXYMETHYL-2-METHOXYMETHYLAZABICYCLO(2.2.2)OCTAN-3-ONE; ANTINEOPLASTIC AGENT; QUINUCLIDINE DERIVATIVE;

EID: 85016437418     PISSN: None     EISSN: 20445385     Source Type: Journal    
DOI: 10.1038/BCJ.2016.60     Document Type: Letter
Times cited : (69)

References (5)
  • 1
    • 0036674617 scopus 로고    scopus 로고
    • Live or let die: The cell's response to p53
    • Vousden KH, Lu X. Live or let die: the cell's response to p53. Nat Rev Cancer 2002; 2: 594–604.
    • (2002) Nat Rev Cancer , vol.2 , pp. 594-604
    • Vousden, K.H.1    Lu, X.2
  • 3
    • 84867615093 scopus 로고    scopus 로고
    • Targeting p53 in vivo: Afirst-in-human study with p53-targeting compound APR-246 in refractory hematologic malignancies and prostate cancer
    • Lehmann S, Bykov VJ, Ali D, Andren O, Cherif H, Tidefelt U et al. Targeting p53 in vivo: afirst-in-human study with p53-targeting compound APR-246 in refractory hematologic malignancies and prostate cancer. J Clin Oncol 2012; 30: 3633–3639.
    • (2012) J Clin Oncol , vol.30 , pp. 3633-3639
    • Lehmann, S.1    Bykov, V.J.2    Ali, D.3    Andren, O.4    Cherif, H.5    Tidefelt, U.6
  • 5
    • 0036128899 scopus 로고    scopus 로고
    • Restoration of the tumor suppressor function to mutant p53 by a low-molecular-weight compound
    • Bykov VJ, Issaeva N, Shilov A, Hultcrantz M, Pugacheva E, Chumakov P et al. Restoration of the tumor suppressor function to mutant p53 by a low-molecular-weight compound. Nat Med 2002; 8: 282–288.
    • (2002) Nat Med , vol.8 , pp. 282-288
    • Bykov, V.J.1    Issaeva, N.2    Shilov, A.3    Hultcrantz, M.4    Pugacheva, E.5    Chumakov, P.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.