A learning health care system using computer-aided diagnosis

Journal of Medical Internet Research

Volumn 19, Issue 3, 2017, Pages

  Cahan, Amos ^a   Cimino, James J ^b  

^a IBM T J WATSON RESEARCH CENTER   (United States)

^b University of Alabama at Birmingham   (United States)

Author keywords

Crowdsourcing; Decision support systems, clinical; Diagnosis support systems; Diagnosis, computer assisted; Diagnostic errors; Knowledge bases; Knowledge management; Pattern recognition, automated; Structured knowledge representation

Indexed keywords

COMPUTER ASSISTED DIAGNOSIS; HEALTH CARE DELIVERY; HUMAN; PROCEDURES;

DELIVERY OF HEALTH CARE; DIAGNOSIS, COMPUTER-ASSISTED; HUMANS;

EID: 85016397972     PISSN: None     EISSN: 14388871     Source Type: Journal    
DOI: 10.2196/jmir.6663     Document Type: Review

References (54)

1. Del Mar C, Doust J, Glasziou P. Clinical Thinking. Malden, MA: Blackwell Publishing Inc; 2006.
2. Kahneman D, Klein G. Conditions for intuitive expertise: A failure to disagree. Am Psychol 2009 Sep;64(6):515-526. [doi: 10.1037/a0016755] [Medline: 19739881]
3. Sotos JG. Zebra Cards: An Aid To Obscure Diagnosis. Mt Vernon, VA: Mt Vernon Book Systems; 2006.
4. Phelps MA, Levitt MA. Pretest probability estimates: A pitfall to the clinical utility of evidence-based medicine?. Acad Emerg Med 2004 Jun;11(6):692-694 [FREE Full text] [Medline: 15175211]
5. Dolan JG, Bordley DR, Mushlin AI. An evaluation of clinicians' subjective prior probability estimates. Med Decis Making 1986;6(4):216-223. [Medline: 3773651]
6. Cahan A, Gilon D, Manor O, Paltiel O. Probabilistic reasoning and clinical decision-making: Do doctors overestimate diagnostic probabilities?. QJM 2003 Oct;96(10):763-769 [FREE Full text] [Medline: 14500863]
7. Balogh EP, Miller BT, Ball JR, editors. Improving Diagnosis in Health Care. Washington, DC: National Academy of Sciences; 2015.
8. McDonald CJ. Medical heuristics: The silent adjudicators of clinical practice. Ann Intern Med 1996 Jan 1;124(1 Pt 1):56-62. [Medline: 7503478]
9. Tversky A, Kahneman D. Judgment under uncertainty: Heuristics and biases. Science 1974 Sep 27;185(4157):1124-1131. [doi: 10.1126/science.185.4157.1124] [Medline: 17835457]
10. Redelmeier DA, Koehler DJ, Liberman V, Tversky A. Probability judgement in medicine: Discounting unspecified possibilities. Med Decis Making 1995;15(3):227-230. [Medline: 7564936]
11. Ledley RS, Lusted LB. The role of computers in medical diagnosis. Med Dok 1961 Jul;5:70-78. [Medline: 13760192]
12. Gorry GA, Barnett GO. Sequential diagnosis by computer. JAMA 1968 Sep 16;205(12):849-854. [Medline: 5695508]
13. Miller RA. Medical diagnostic decision support systems-past, present, and future: A threaded bibliography and brief commentary. J Am Med Inform Assoc 1994;1(1):8-27 [FREE Full text] [Medline: 7719792]
14. Miller RA. Computer-assisted diagnostic decision support: History, challenges, and possible paths forward. Adv Health Sci Educ Theory Pract 2009 Sep;14 Suppl 1:89-106. [doi: 10.1007/s10459-009-9186-y] [Medline: 19672686]
15. Mitchell JA, Gerdin U, Lindberg DA, Lovis C, Martin-Sanchez FJ, Miller RA, et al. 50 years of informatics research on decision support: what's next. Methods Inf Med 2011;50(6):525-535. [doi: 10.3414/ME11-06-0004] [Medline: 22146915]
16. Garg AX, Adhikari NKJ, McDonald H, Rosas-Arellano MP, Devereaux PJ, Beyene J, et al. Effects of computerized clinical decision support systems on practitioner performance and patient outcomes: A systematic review. JAMA 2005 Mar 9;293(10):1223-1238. [doi: 10.1001/jama.293.10.1223] [Medline: 15755945]
17. Barnett GO, Famiglietti KT, Kim RJ, Hoffer EP, Feldman MJ. DXplain on the Internet. Proc AMIA Symp 1998:607-611 [FREE Full text] [Medline: 9929291]
18. Berger SA. GIDEON: A computer program for diagnosis, simulation, and informatics in the fields of geographic medicine and emerging diseases. Emerg Infect Dis 2001;7(3 Suppl):550 [FREE Full text] [doi: 10.3201/eid0707.010729] [Medline: 11485667]
19. Vardell E, Moore M. Isabel, a clinical decision support system. Med Ref Serv Q 2011;30(2):158-166. [doi: 10.1080/02763869.2011.562800] [Medline: 21534115]
20. Riches N, Panagioti M, Alam R, Cheraghi-Sohi S, Campbell S, Esmail A, et al. The effectiveness of electronic differential diagnoses (DDX) generators: A systematic review and meta-analysis. PLoS One 2016;11(3):e0148991 [FREE Full text] [doi: 10.1371/journal.pone.0148991] [Medline: 26954234]
21. El-Kareh R, Hasan O, Schiff GD. Use of health information technology to reduce diagnostic errors. BMJ Qual Saf 2013 Oct;22 Suppl 2:ii40-ii51 [FREE Full text] [doi: 10.1136/bmjqs-2013-001884] [Medline: 23852973]
22. Lupton D, Jutel A. 'It's like having a physician in your pocket!' A critical analysis of self-diagnosis smartphone apps. Soc Sci Med 2015 May;133:128-135. [doi: 10.1016/j.socscimed.2015.04.004] [Medline: 25864149]
23. Semigran HL, Linder JA, Gidengil C, Mehrotra A. Evaluation of symptom checkers for self diagnosis and triage: Audit study. BMJ 2015;351:h3480 [FREE Full text] [Medline: 26157077]
24. Berner ES, Webster GD, Shugerman AA, Jackson JR, Algina J, Baker AL, et al. Performance of four computer-based diagnostic systems. N Engl J Med 1994 Jun 23;330(25):1792-1796. [doi: 10.1056/NEJM199406233302506] [Medline: 8190157]
25. Umscheid CA, Hanson CW. A follow-up report card on computer-assisted diagnosis-the grade: C+. J Gen Intern Med 2012 Feb;27(2):142-144 [FREE Full text] [doi: 10.1007/s11606-011-1944-x] [Medline: 22160816]
26. Bond WF, Schwartz LM, Weaver KR, Levick D, Giuliano M, Graber ML. Differential diagnosis generators: An evaluation of currently available computer programs. J Gen Intern Med 2012 Feb;27(2):213-219 [FREE Full text] [doi: 10.1007/s11606-011-1804-8] [Medline: 21789717]
27. Tang H, Ng JKH. Googling for a diagnosis-use of Google as a diagnostic aid: Internet based study. BMJ 2006 Dec 2;333(7579):1143-1145 [FREE Full text] [doi: 10.1136/bmj.39003.640567.AE] [Medline: 17098763]
28. Warner H, Haug P, Bouhaddou O, Lincoln M, Warner H, Sorenson D. ILIAD as an expert consultant to teach differential diagnosis. Proc Annu Symp Comput Appl Med Care 1988;Nov 9:371-376.
29. Miller RA, McNeil MA, Challinor SM, Masarie FE, Myers JD. The INTERNIST-1/QUICK MEDICAL REFERENCE project-status report. West J Med 1986 Dec;145(6):816-822 [FREE Full text] [Medline: 3544509]
30. DxPlain. Boston, MA: The Massachussets General Hospital Laboratory of Computer Science; 2015. URL: Http://www.mghlcs.org/projects/dxplain [accessed 2016-09-18] [WebCite Cache ID 6kcFQQxqe]
31. Ledley RS, Lusted LB. Reasoning foundations of medical diagnosis; symbolic logic, probability, and value theory aid our understanding of how physicians reason. Science 1959 Jul 3;130(3366):9-21. [Medline: 13668531]
32. Human Diagnosis Project.: Human Dx, Ltd; 2016. URL: Https://www.humandx.org/ [accessed 2016-09-19] [WebCite Cache ID 6kdEt5zBX]
33. Pryor TA, Gardner RM, Clayton PD, Warner HR. The HELP system. J Med Syst 1983 Apr;7(2):87-102. [Medline: 6688267]
34. Graber ML, Mathew A. Performance of a web-based clinical diagnosis support system for internists. J Gen Intern Med 2008 Jan;23 Suppl 1:37-40 [FREE Full text] [doi: 10.1007/s11606-007-0271-8] [Medline: 18095042]
35. Weber GM, Mandl KD, Kohane IS. Finding the missing link for big biomedical data. JAMA 2014 Jun 25;311(24):2479-2480. [doi: 10.1001/jama.2014.4228] [Medline: 24854141]
36. Miller RA, Pople HE, Myers JD. Internist-1, an experimental computer-based diagnostic consultant for general internal medicine. N Engl J Med 1982 Aug 19;307(8):468-476. [doi: 10.1056/NEJM198208193070803] [Medline: 7048091]
37. Kohane I. Temporal Reasoning in Medical Expert Systems: Technical Report. Cambridge, MA: Massachusetts Institute of Technology; 1987.
38. [No authors listed]. Present and future of isolation systems in Auckland. N Z Med J 1975 Dec 24;82(554):410-413. [Medline: 1062725]
39. Shahar Y, Combi C. Timing is everything. Time-oriented clinical information systems. West J Med 1998 Feb;168(2):105-113 [FREE Full text] [Medline: 9499744]
40. Denekamp Y, Gal A. A clinical problem-oriented decision support model based on extended temporal database functionalities. AMIA Annu Symp Proc 2005:936 [FREE Full text] [Medline: 16779223]
41. Williamson M, Snyder L, Wallach J. Wallach's Interpretation of Diagnostic Tests. 9th edition. Philadelphia, PA: Wolters Kluwer; 2011.
42. Thorner AR, Walker DH, Petri WA. Rocky Mountain spotted fever. Clin Infect Dis 1998 Dec;27(6):1353-9; quiz 1360. [Medline: 9868640]
43. Pauker SG, Kassirer JP. The threshold approach to clinical decision making. N Engl J Med 1980 May 15;302(20):1109-1117. [doi: 10.1056/NEJM198005153022003] [Medline: 7366635]
44. Hauser RG, Jackson BR, Shirts BH. A bayesian approach to laboratory utilization management. J Pathol Inform 2015;6:10 [FREE Full text] [doi: 10.4103/2153-3539.151921] [Medline: 25774321]
45. Halkin A, Reichman J, Schwaber M, Paltiel O, Brezis M. Likelihood ratios: Getting diagnostic testing into perspective. QJM 1998 Apr;91(4):247-258 [FREE Full text] [Medline: 9666947]
46. AHIP white paper focuses on patients and diagnostic imaging. Washington, DC: AHIP Coverage; 2011 Apr 18. URL: Http:/ /03664d9.netsolhost.com/devwordpress/2011/04/18/ahip-white-paper-focuses-on-patients-and-diagnostic-imaging/ [accessed 2016-09-18] [WebCite Cache ID 6kcGEbVEn]
47. Reich C, Ryan PB, Stang PE, Rocca M. Evaluation of alternative standardized terminologies for medical conditions within a network of observational healthcare databases. J Biomed Inform 2012 Aug;45(4):689-696 [FREE Full text] [doi: 10.1016/j.jbi.2012.05.002] [Medline: 22683994]
48. Hripcsak G, Duke JD, Shah NH, Reich CG, Huser V, Schuemie MJ, et al. Observational Health Data Sciences and Informatics (OHDSI): Opportunities for observational researchers. Stud Health Technol Inform 2015;216:574-578 [FREE Full text] [Medline: 26262116]
49. Posey JE, Harel T, Liu P, Rosenfeld JA, James RA, Coban Akdemir ZH, et al. Resolution of disease phenotypes resulting from multilocus genomic variation. N Engl J Med 2017 Jan 05;376(1):21-31. [doi: 10.1056/NEJMoa1516767] [Medline: 27959697]
50. Fung CH. Computerized condition-specific templates for improving care of geriatric syndromes in a primary care setting. J Gen Intern Med 2006 Sep;21(9):989-994 [FREE Full text] [doi: 10.1111/j.1525-1497.2006.00522.x] [Medline: 16918747]
51. Archer JC. State of the science in health professional education: Effective feedback. Med Educ 2010 Jan;44(1):101-108. [doi: 10.1111/j.1365-2923.2009.03546.x] [Medline: 20078761]
52. McIver DJ, Brownstein JS. Wikipedia usage estimates prevalence of influenza-like illness in the United States in near real-time. PLoS Comput Biol 2014 Apr;10(4):e1003581 [FREE Full text] [doi: 10.1371/journal.pcbi.1003581] [Medline: 24743682]
53. Velardi P, Stilo G, Tozzi AE, Gesualdo F. Twitter mining for fine-grained syndromic surveillance. Artif Intell Med 2014 Jul;61(3):153-163. [doi: 10.1016/j.artmed.2014.01.002] [Medline: 24613716]
54. World Health Organization. Diagnostic errors: Technical series on safer primary care. Geneva, Switzerland: WHO; 2016. URL: Http://apps.who.int/iris/bitstream/10665/252410/1/9789241511636-eng.pdf?ua=1 [accessed 2017-03-02] [WebCite Cache ID 6ofYC0mp5]