Tissue transglutaminase modulates vascular stiffness and function through crosslinking-dependent and crosslinking-independent functions

Journal of the American Heart Association

Volumn 6, Issue 2, 2017, Pages

  Steppan, Jochen ^a   Bergman, Yehudit ^a   Viegas, Kayla ^e   Armstrong, Dinani ^a   Tan, Siqi ^b   Wang, Huilei ^c   Melucci, Sean ^b   Hori, Daijiro ^a   Park, Sung Yong ^f   Barreto, Sebastian F ^a   Isak, Abraham ^d   Jandu, Sandeep ^a   Flavahan, Nicholas ^a   Butlin, Mark ^e   An, Steven S ^b,d   Avolio, Alberto ^e   Berkowitz, Dan E ^a,c   Halushka, Marc K ^a   Santhanam, Lakshmi ^a,c  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Johns Hopkins University   (United States)

^c Johns Hopkins University   (United States)

^d Johns Hopkins University   (United States)

^e MACQUARIE UNIVERSITY   (Australia)

^f Yonsei University   (South Korea)

Author keywords

Crosslinking; Matrix remodeling; Tissue transglutaminase; Vascular biology; Vascular disease; Vascular smooth muscle; Vascular stiffness; Vessel

Indexed keywords

COLLAGEN; FIBRONECTIN; PHENYLEPHRINE; PROTEIN GLUTAMINE GAMMA GLUTAMYLTRANSFERASE; GUANINE NUCLEOTIDE BINDING PROTEIN; PROTEIN GLUTAMINE GAMMA GLUTAMYLTRANSFERASE 2;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTIC SMOOTH MUSCLE CELL; ARTERIAL STIFFNESS; ARTERY MEDIA; ARTICLE; ATHEROSCLEROTIC PLAQUE; BIOMECHANICS; BLOOD VESSEL FUNCTION; BLOOD VESSEL REACTIVITY; CELL ADHESION; CELL MOTILITY; CELL PROLIFERATION; CONTROLLED STUDY; CORONARY ARTERY; CYTOMETRY; CYTOSKELETON; ENZYME LOCALIZATION; GUINEA PIG; HUMAN; HUMAN TISSUE; IMPEDANCE; MALE; MOUSE; MYOGRAPHY; NONHUMAN; PROTEIN ASSEMBLY; PROTEIN CROSS LINKING; PROTEIN EXPRESSION; TENSILE STRENGTH; VASOCONSTRICTION; ANIMAL; APOPTOSIS; BIOSYNTHESIS; CELL CULTURE; CELL DIFFERENTIATION; CELL MOTION; CORONARY BLOOD VESSEL; CYTOLOGY; ENZYMOLOGY; IMMUNOHISTOCHEMISTRY; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; PULSE WAVE; THORACIC AORTA; TISSUE MICROARRAY; VASCULAR SMOOTH MUSCLE; WESTERN BLOTTING;

ANIMALS; AORTA, THORACIC; APOPTOSIS; BLOTTING, WESTERN; CELL DIFFERENTIATION; CELL MOVEMENT; CELL PROLIFERATION; CELLS, CULTURED; COLLAGEN; CORONARY VESSELS; GTP-BINDING PROTEINS; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MICE; MODELS, ANIMAL; MUSCLE, SMOOTH, VASCULAR; MYOGRAPHY; PULSE WAVE ANALYSIS; TISSUE ARRAY ANALYSIS; TRANSGLUTAMINASES; VASCULAR STIFFNESS;

EID: 85015983359     PISSN: None     EISSN: 20479980     Source Type: Journal    
DOI: 10.1161/JAHA.116.004161     Document Type: Article

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