Association between maternal body mass index in early pregnancy and incidence of cerebral palsy

JAMA - Journal of the American Medical Association

Volumn 317, Issue 9, 2017, Pages 925-936

  Villamor, Eduardo ^a,b   Tedroff, Kristina ^b   Peterson, Mark ^a   Johansson, Stefan ^b   Neovius, Martin ^a   Petersson, Gunnar ^a,b   Cnattingius, Sven ^b  

^a UNIVERSITY OF MICHIGAN   (United States)

^b KAROLINSKA INSTITUTE   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; BODY HEIGHT; BODY MASS; CEREBRAL PALSY; CHILD; COHORT ANALYSIS; EDUCATION; FEMALE; FIRST TRIMESTER PREGNANCY; FOLLOW UP; GESTATIONAL AGE; HUMAN; MAJOR CLINICAL STUDY; MALE; MATERNAL AGE; MATERNAL OBESITY; MORBIDITY; OBSTETRIC DELIVERY; POPULATION RESEARCH; REGISTER; RETROSPECTIVE STUDY; SMOKING; SWEDEN; UNDERWEIGHT; ADOLESCENT; COMPLICATION; INCIDENCE; INFANT; NEWBORN; OBESITY; OVERWEIGHT; PREGNANCY; PREGNANCY COMPLICATIONS; PRESCHOOL CHILD; RISK FACTOR; YOUNG ADULT;

ADOLESCENT; ADULT; BODY MASS INDEX; CEREBRAL PALSY; CHILD; CHILD, PRESCHOOL; COHORT STUDIES; FEMALE; GESTATIONAL AGE; HUMANS; INCIDENCE; INFANT; INFANT, NEWBORN; OBESITY; OVERWEIGHT; PREGNANCY; PREGNANCY COMPLICATIONS; RETROSPECTIVE STUDIES; RISK FACTORS; SWEDEN; YOUNG ADULT;

EID: 85015890774     PISSN: 00987484     EISSN: 15383598     Source Type: Journal    
DOI: 10.1001/jama.2017.0945     Document Type: Article

References (47)

1. Christensen D, Van Naarden Braun K, Doernberg NS, et al. Prevalence of cerebral palsy, co-occurring autism spectrum disorders, and motor functioning-Autism and Developmental Disabilities Monitoring Network, USA, 2008. Dev Med Child Neurol. 2014;56(1):59-65.
2. Himmelmann K, Uvebrant P. The panorama of cerebral palsy in Sweden. XI: Changing patterns in the birth-year period 2003-2006. Acta Paediatr. 2014;103(6):618-624.
3. Peterson MD, Ryan JM, Hurvitz EA, Mahmoudi E. Chronic conditions in adults with cerebral palsy. JAMA. 2015;314(21):2303-2305.
4. Kruse M, Michelsen SI, Flachs EM, Bronnum-Hansen H, Madsen M, Uldall P. Lifetime costs of cerebral palsy. Dev Med Child Neurol. 2009; 51(8):622-628.
5. Nelson KB, Blair E. Prenatal factors in singletons with cerebral palsy born at or near term. N Engl J Med. 2015;373(10):946-953.
6. Villamor E, Cnattingius S. Interpregnancy weight change and risk of adverse pregnancy outcomes: A population-based study. Lancet. 2006;368 (9542):1164-1170.
7. Cnattingius S, Villamor E, Johansson S, et al. Maternal obesity and risk of preterm delivery. JAMA. 2013;309(22):2362-2370.
8. Persson M, Johansson S, Villamor E, Cnattingius S. Maternal overweight and obesity and risks of severe birth-asphyxia-related complications in term infants: A population-based cohort study in Sweden. PLoS Med. 2014;11(5): E1001648.
9. LiM, Fallin MD, Riley A, et al. The association of maternal obesity and diabetes with autism and other developmental disabilities. Pediatrics. 2016; 137(2):e20152206.
10. Walstab J, Bell R, Reddihough D, Brennecke S, Bessell C, Beischer N. Antenatal and intrapartum antecedents of cerebral palsy: A case-control study. Aust N Z J Obstet Gynaecol. 2002;42(2):138-146.
11. Crisham Janik MD, Newman TB, Cheng YW, Xing G, Gilbert WM,Wu YW. Maternal diagnosis of obesity and risk of cerebral palsy in the child. J Pediatr. 2013;163(5):1307-1312.
12. Pan C, Deroche CB, Mann JR, McDermott S, Hardin JW. Is prepregnancy obesity associated with risk of cerebral palsy and epilepsy in children?. J Child Neurol. 2014;29(12):NP196-NP201.
13. Ahlin K, Himmelmann K, Nilsson S, Sengpiel V, Jacobsson B. Antecedents of cerebral palsy according to severity of motor impairment. Acta Obstet Gynecol Scand. 2016;95(7):793-802.
14. Forthun I, Wilcox AJ, Strandberg-Larsen K, et al. Maternal prepregnancy BMI and risk of cerebral palsy in offspring. Pediatrics. 2016;138(4):1-9.
15. Ludvigsson JF, Otterblad-Olausson P, Pettersson BU, Ekbom A. The Swedish personal identity number: Possibilities and pitfalls in healthcare and medical research. Eur J Epidemiol. 2009;24(11):659-667.
16. Swedish National Board of Health andWelfare. The Swedish Medical Birth Register: A summary of content and quality. http://www.socialstyrelsen.se/Lists/Artikelkatalog/Attachments/10655/2003-112-3-20031123.pdf. Accessed February 15, 2016.
17. Ludvigsson JF, Andersson E, Ekbom A, et al. External review and validation of the Swedish national inpatient register. BMC Public Health. 2011; 11:450.
18. Swedish National Board of Health andWelfare. Quality and content in the Swedish Patient Register [in Swedish]. http://www.socialstyrelsen.se/Lists/Artikelkatalog/Attachments/8306/2009-125-15-200912515-rev2.pdf. Accessed February 19, 2016.
19. Swedish National Board of Health andWelfare. Causes of death. http://www.socialstyrelsen.se/statistics/statisticaldatabase/help/causeofdeath. Accessed February 19, 2016.
20. Ludvigsson JF, Almqvist C, Bonamy AK, et al. Registers of the Swedish total population and their use in medical research. Eur J Epidemiol. 2016;31(2): 125-136.
21. Statistics Sweden. Evaluation of the Swedish register of education. http://www.scb.se/statistik/-publikationer/BE9999-2006A01-BR-BE96ST0604.pdf. Accessed February 15,2016.
22. Villamor E, Cnattingius S. Interpregnancy weight change and risk of preterm delivery. Obesity (Silver Spring). 2016;24(3):727-734.
23. Villamor E, Bosch RJ. Optimal treatment of replicate measurements in anthropometric studies. Ann Hum Biol. 2015;42(5):507-510.
24. World Health Organization. Global database on body mass index: BMI classification. http://apps .who.int/bmi/index.jsp?introPage=intro-3.html. Accessed February 19, 2016.
25. George L, Granath F, Johansson AL, Cnattingius S. Self-reported nicotine exposure and plasma levels of cotinine in early and late pregnancy. Acta Obstet Gynecol Scand. 2006;85(11):1331-1337.
26. Hogberg U, Larsson N. Early dating by ultrasound and perinatal outcome: A cohort study. Acta Obstet Gynecol Scand. 1997;76(10):907-912.
27. Durrleman S, Simon R. Flexible regression models with cubic splines. Stat Med. 1989;8(5):551-561.
28. Johansson S, Villamor E, Altman M, Bonamy AK, Granath F, Cnattingius S. Maternal overweight and obesity in early pregnancy and risk of infant mortality: A population based cohort study in Sweden. BMJ. 2014;349:g6572.
29. Greenland S, Pearl J, Robins JM. Causal diagrams for epidemiologic research. Epidemiology. 1999;10(1):37-48.
30. Valeri L, Vanderweele TJ. Mediation analysis allowing for exposure-mediator interactions and causal interpretation: Theoretical assumptions and implementation with SAS and SPSS macros. Psychol Methods. 2013;18(2):137-150.
31. Valeri L, VanderWeele TJ. SAS macro for causal mediation analysis with survival data. Epidemiology. 2015;26(2):e23-e24.
32. Schafer J. Analysis of Incomplete Multivariate Data. New York, NY: Chapman and Hall; 1997.
33. Carter BS, Haverkamp AD, Merenstein GB. The definition of acute perinatal asphyxia. Clin Perinatol. 1993;20(2):287-304.
34. Hoffmann AL, Hjortdal JO, Secher NJ,Weile B. The relationship between Apgar score, umbilical artery pH and operative delivery for fetal distress in 2778 infants born at term. Eur J Obstet Gynecol Reprod Biol. 1991;38(2):97-101.
35. Ellenberg JH, Nelson KB. The association of cerebral palsy with birth asphyxia: A definitional quagmire. Dev Med Child Neurol. 2013;55(3):210-216.
36. Ovesen P, Rasmussen S, Kesmodel U. Effect of prepregnancy maternal overweight and obesity on pregnancy outcome. Obstet Gynecol. 2011; 118(2 Pt 1):305-312.
37. Martinez-Biarge M, Diez-Sebastian J,Wusthoff CJ, Mercuri E, Cowan FM. Antepartum and intrapartum factors preceding neonatal hypoxic-ischemic encephalopathy. Pediatrics. 2013; 132(4):e952-e959.
38. HAPO Study Cooperative Research Group. Hyperglycaemia and Adverse Pregnancy Outcome (HAPO) Study: Associations with maternal body mass index. BJOG. 2010;117(5):575-584.
39. Edlow AG, Hui L, Wick HC, Fried I, Bianchi DW. Assessing the fetal effects of maternal obesity via transcriptomic analysis of cord blood: A prospective case-control study. BJOG. 2016;123(2):180-189.
40. Andersen GL, Irgens LM, Haagaas I, Skranes JS, Meberg AE, Vik T. Cerebral palsy in Norway: Prevalence, subtypes and severity. Eur J Paediatr Neurol. 2008;12(1):4-13.
41. Himmelmann K, Hagberg G, Wiklund LM, Eek MN, Uvebrant P. Dyskinetic cerebral palsy: A population-based study of children born between 1991 and 1998. Dev Med Child Neurol. 2007;49(4): 246-251.
42. Surveillance of Cerebral Palsy in Europe. Surveillance of cerebral palsy in Europe: A collaboration of cerebral palsy surveys and registers. Surveillance of Cerebral Palsy in Europe (SCPE). Dev Med Child Neurol. 2000;42(12):816-824.
43. Rosenbaum P, Paneth N, Leviton A, et al. A report: The definition and classification of cerebral palsy April 2006. Dev Med Child Neurol Suppl. 2007;109:8-14.
44. NCD Risk Factor Collaboration. Trends in adult body-mass index in 200 countries from 1975 to 2014: A pooled analysis of 1698 population-based measurement studies with 19 2 million participants. Lancet. 2016;387(10026):1377-1396.
45. Branum AM, Kirmeyer SE, Gregory EC. Prepregnancy body mass index by maternal characteristics and state: Data from the birth certificate, 2014. Natl Vital Stat Rep. 2016; 65(6):1-11.
46. Sturm R, Hattori A. Morbid obesity rates continue to rise rapidly in the United States. Int J Obes (Lond). 2013;37(6):889-891.
47. World Health Organization. International statistical classification of diseases and related health problems 10th revision. http://apps.who.int/classifications/icd10/browse/2010/en. Accessed February 3, 2017.