Lactobacillus casei rhamnosus Lcr35 in the Management of Functional Constipation in Children: A Randomized Trial

Journal of Pediatrics

Volumn 184, Issue , 2017, Pages 101-105.e1

  Wojtyniak, Katarzyna ^a   Horvath, Andrea ^a   Dziechciarz, Piotr ^a   Szajewska, Hania ^a  

^a MEDICAL UNIVERSITY OF WARSAW   (Poland)

Author keywords

gastrointestinal disorders; pediatrics; probiotics

Indexed keywords

LCR 35; MACROGOL 3350; PROBIOTIC AGENT; UNCLASSIFIED DRUG;

ABDOMINAL PAIN; ADVERSE OUTCOME; ARTICLE; CHILD; CHILD HEALTH CARE; COLONY FORMING UNIT; CONSTIPATION; CONTROLLED STUDY; DEFECATION HABIT; DISEASE DURATION; DOUBLE BLIND PROCEDURE; FECES IMPACTION; FEMALE; FLATULENCE; FOLLOW UP; FUNCTIONAL CONSTIPATION; GASTROINTESTINAL MOTILITY; HUMAN; LACTOBACILLUS RHAMNOSUS; LOSS OF APPETITE; MAJOR CLINICAL STUDY; MALE; ONSET AGE; OUTCOME ASSESSMENT; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RISK FACTOR; SCHOOL CHILD; TOILETING; BIOLOGICAL THERAPY; LACTOBACILLUS CASEI; PRESCHOOL CHILD;

BIOLOGICAL THERAPY; CHILD, PRESCHOOL; CONSTIPATION; DOUBLE-BLIND METHOD; FEMALE; HUMANS; LACTOBACILLUS CASEI; LACTOBACILLUS RHAMNOSUS; MALE;

EID: 85015690853     PISSN: 00223476     EISSN: 10976833     Source Type: Journal    
DOI: 10.1016/j.jpeds.2017.01.068     Document Type: Article

References (28)

1. 1 Mugie, S.M., Benninga, M.A., Di Lorenzo, C., Epidemiology of constipation in children and adults: a systematic review. Best Pract Res Clin Gastroenterol 25 (2011), 3–18.
2. 2 Tabbers, M.M., Dilorenzo, C., Berger, M.Y., Faure, C., Langendam, M.W., Nurko, S., et al. Evaluation and treatment of functional constipation in infants and children: evidence-based recommendations from ESPGHAN and NASPGHAN. J Pediatr Gastroenterol Nutr 58 (2014), 265–281.
3. 3 Attaluri, A., Jackson, M., Valestin, J., Rao, S.S., Methanogenic flora is associated with altered colonic transit but not stool characteristics in constipation without IBS. Am J Gastroenterol 105 (2010), 1407–1411.
4. 4 Zhu, L., Liu, W., Alkhouri, R., Baker, R.D., Bard, J.E., Quigley, E.M., et al. Structural changes in the gut microbiome of constipated patients. Physiol Genomics 46 (2014), 679–686.
5. 5 Khalif, I.L., Quigley, E.M., Konovitch, E.A., Maximova, I.D., Alternations in the colonic flora and intestinal permeability and evidence of immune activation in chronic constipation. Dig Liver Dis 37 (2005), 838–849.
6. 6 Zhao, Y., Yu, Y.B., Intestinal microbiota and chronic constipation. Springerplus, 5, 2016, 1130.
7. 7 Hill, C., Guarner, F., Reid, G., Gibson, G.R., Merenstein, D.J., Pot, B., et al. Expert consensus document. The International Scientific Association for Probiotics and Prebiotics consensus statement on the scope and appropriate use of the term probiotic. Nat Rev Gastroenterol Hepatol 11 (2014), 506–514.
8. 8 Ait-Belgnaoui, A., Han, W., Lamine, F., Eutamene, H., Fioramonti, J., Bueno, L., et al. Lactobacillus farciminis treatment suppresses stress induced visceral hypersensitivity: a possible action through interaction with epithelial cell cytoskeleton contraction. Gut 55 (2006), 1090–1094.
9. 9 Rousseaux, C., Thuru, X., Gelot, A., Barnich, N., Neut, C., Dubuquoy, L., et al. Lactobacillus acidophilus modulates intestinal pain and induces opioid and cannabinoid receptors. Nat Med 13 (2007), 35–37.
10. 10 Bueno, L., de Ponti, F., Fried, M., Kullak-Ublick, G.A., Kwiatek, M.A., Pohl, D., et al. Serotonergic and non-serotonergic targets in the pharmacotherapy of visceral hypersensitivity. Neurogastroenterol Motil 19:suppl (2007), 89–119.
11. 11 Quigley, E.M., Bacteria: a new player in gastrointestinal motility disorders—infections, bacterial overgrowth, and probiotics. Gastroenterol Clin North Am 36 (2007), 735–748.
12. 12 Waller, P.A., Gopal, P.K., Leyer, G.J., Ouwehand, A.C., Reifer, C., Stewart, M.E., et al. Dose-response effect of Bifidobacterium lactis HN019 on whole gut transit time and functional gastrointestinal symptoms in adults. Scand J Gastroenterol 46 (2011), 1057–1064.
13. 13 Salminen, S., Salminen, E., Lactulose, lactic acid bacteria, intestinal microecology and mucosal protection. Scand J Gastroenterol Suppl 222 (1997), 45–48.
14. 14 Bu, L.N., Chang, M.H., Ni, Y.H., Chen, H.L., Cheng, C.C., Lactobacillus casei rhamnosus Lcr35 in children with chronic constipation. Pediatr Int 49 (2007), 485–490.
15. 15 Moher, D., Hopewell, S., Schulz, K.F., Montori, V., Gøtzsche, P.C., Devereaux, P.J., et al. CONSORT 2010 explanation and elaboration: updated guidelines for reporting parallel group randomised trials. BMJ, 340, 2010, c869.
16. 16 Hyman, P.E., Milla, P.J., Benninga, M.A., Davidson, G.P., Fleisher, D.F., Taminiau, J., Childhood functional gastrointestinal disorders: neonate/toddler. Gastroenterology 130 (2006), 1519–1526.
17. 17 Rasquin, A., Di Lorenzo, C., Forbes, D., Guiraldes, E., Hyams, J.S., Staiano, A., et al. Childhood functional gastrointestinal disorders: child/adolescent. Gastroenterology 130 (2006), 1527–1537.
18. 18 Lewis, S.J., Heaton, K.W., Stool form scale as a useful guide to intestinal transit time. Scand J Gastroenterol 32 (1997), 920–924.
19. 19 Chmielewska, A., Horvath, A., Dziechciarz, P., Szajewska, H., Glucomannan is not effective for the treatment of functional constipation in children: a double-blind, placebo-controlled, randomized trial. Clin Nutr 30 (2011), 462–468.
20. 20 Nurko, S., Youssef, N.N., Sabri, M., Langseder, A., McGowan, J., Cleveland, M., et al. PEG3350 in the treatment of childhood constipation: a multicenter, double-blinded, placebo-controlled trial. J Pediatr 153 (2008), 254–261.
21. 21 Koppen, I.J.N., Benninga, M.A., Tabbers, M.M., Is there a role for pre-, pro- and symbiotics in the treatment of functional constipation in children? A systematic review. J Pediatr Gastroenterol Nutr 63 (2016), S27–35.
22. 22 Guerra, P.V., Lima, L.N., Souza, T.C., Mazochi, V., Penna, F.J., Silva, A.M., et al. Pediatric functional constipation treatment with Bifidobacterium-containing yogurt: a crossover, double-blind, controlled trial. World J Gastroenterol 17 (2011), 3916–3921.
23. 23 Coccorullo, P., Strisciuglio, C., Martinelli, M., Miele, E., Greco, L., Staiano, A., Lactobacillus reuteri (DSM 17938) in infants with functional chronic constipation: a double-blind, randomized, placebo-controlled study. J Pediatr 157 (2010), 598–602.
24. 24 Sadeghzadeh, M., Rabieefar, A., Khoshnevisasl, P., Mousavinasab, N., Eftekhari, K., The effect of probiotics on childhood constipation: a randomized controlled double blind clinical trial. Int J Pediatr, 2014, 2014, 937212.
25. 25 Banaszkiewicz, A., Szajewska, H., Ineffectiveness of Lactobacillus GG as an adjunct to lactulose for the treatment of constipation in children: a double-blind, placebo controlled randomized trial. J Pediatr 146 (2005), 364–369.
26. 26 Tabbers, M.M., Chmielewska, A., Roseboom, M.G., Crastes, N., Perrin, C., Reitsma, J.B., et al. Fermented milk containing Bifidobacterium lactis DN-173 010 in childhood constipation: a randomized, double-blind, controlled trial. Pediatrics 127 (2011), e1392–9.
27. 27 Benninga, M.A., Nurko, S., Faure, C., Hyman, P.E., Roberts, I., Schechter, N.L., Childhood functional gastrointestinal disorders: neonate/toddler. Gastroenterology 150 (2016), 1433–1455.
28. 28 Hyams, J.S., Di Lorenzo, C., Saps, M., Shulman, R.J., Staiano, A., van Tilburg, M., Childhood functional gastrointestinal disorders: child/adolescent. Gastroenterology 150 (2016), 1456–1468.