-
1
-
-
84879796970
-
Circulating tumour cells and cell-free DNA as tools for managing breast cancer
-
De Mattos-Arruda L, Cortes J, Santarpia L, et al. Circulating tumour cells and cell-free DNA as tools for managing breast cancer. Nat Rev Clin Oncol 2013;10:377-89.
-
(2013)
Nat Rev Clin Oncol
, vol.10
, pp. 377-389
-
-
De Mattos-Arruda, L.1
Cortes, J.2
Santarpia, L.3
-
5
-
-
84875520648
-
Analysis of circulating tumor DNA to monitor metastatic breast cancer
-
Dawson SJ, Tsui DW, Murtaza M, et al. Analysis of circulating tumor DNA to monitor metastatic breast cancer. N Engl J Med 2013;368:1199-209.
-
(2013)
N Engl J Med
, vol.368
, pp. 1199-1209
-
-
Dawson, S.J.1
Tsui, D.W.2
Murtaza, M.3
-
6
-
-
84877579861
-
Non-invasive analysis of acquired resistance to cancer therapy by sequencing of plasma DNA
-
Murtaza M, Dawson SJ, Tsui DW, et al. Non-invasive analysis of acquired resistance to cancer therapy by sequencing of plasma DNA. Nature 2013;497:108-12.
-
(2013)
Nature
, vol.497
, pp. 108-112
-
-
Murtaza, M.1
Dawson, S.J.2
Tsui, D.W.3
-
7
-
-
84861746437
-
Noninvasive identification and monitoring of cancer mutations by targeted deep sequencing of plasma DNA
-
Forshew T, Murtaza M, Parkinson C, et al. Noninvasive identification and monitoring of cancer mutations by targeted deep sequencing of plasma DNA. Sci Transl Med 2012;4:136ra68.
-
(2012)
Sci Transl Med
, vol.4
-
-
Forshew, T.1
Murtaza, M.2
Parkinson, C.3
-
8
-
-
63449103435
-
Single-molecule detection of epidermal growth factor receptor mutations in plasma by microfluidics digital PCR in non-small cell lung cancer patients
-
Yung TK, Chan KC, Mok TS, et al. Single-molecule detection of epidermal growth factor receptor mutations in plasma by microfluidics digital PCR in non-small cell lung cancer patients. Clin Cancer Res 2009;15:2076-84.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 2076-2084
-
-
Yung, T.K.1
Chan, K.C.2
Mok, T.S.3
-
9
-
-
12144289677
-
Mechanism of activation of the RAF-ERK signaling pathway by oncogenic mutations of B-RAF
-
Wan PT, Garnett MJ, Roe SM, et al. Mechanism of activation of the RAF-ERK signaling pathway by oncogenic mutations of B-RAF. Cell 2004;116:855-67.
-
(2004)
Cell
, vol.116
, pp. 855-867
-
-
Wan, P.T.1
Garnett, M.J.2
Roe, S.M.3
-
10
-
-
50349091081
-
Prognostic significance of defective mismatch repair and BRAF V600E in patients with colon cancer
-
French AJ, Sargent DJ, Burgart LJ, et al. Prognostic significance of defective mismatch repair and BRAF V600E in patients with colon cancer. Clin Cancer Res 2008;14:3408-15.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 3408-3415
-
-
French, A.J.1
Sargent, D.J.2
Burgart, L.J.3
-
11
-
-
33846016995
-
BRAF mutations in papillary thyroid carcinoma
-
Wojciechowska K, Lewinski A. BRAF mutations in papillary thyroid carcinoma. Endocr Regul 2006;40:129-38.
-
(2006)
Endocr Regul
, vol.40
, pp. 129-138
-
-
Wojciechowska, K.1
Lewinski, A.2
-
12
-
-
79251490374
-
New driver mutations in non-small-cell lung cancer
-
Pao W, Girard N. New driver mutations in non-small-cell lung cancer. Lancet Oncol 2011;12:175-80.
-
(2011)
Lancet Oncol
, vol.12
, pp. 175-180
-
-
Pao, W.1
Girard, N.2
-
13
-
-
18444374405
-
Mutations of the BRAF gene in human cancer
-
Davies H, Bignell GR, Cox C, et al. Mutations of the BRAF gene in human cancer. Nature 2002;417:949-54.
-
(2002)
Nature
, vol.417
, pp. 949-954
-
-
Davies, H.1
Bignell, G.R.2
Cox, C.3
-
14
-
-
1842428668
-
Incidence of BRAF oncogene mutation and clinical relevance for primary cutaneous melanomas
-
Shinozaki M, Fujimoto A, Morton DL, et al. Incidence of BRAF oncogene mutation and clinical relevance for primary cutaneous melanomas. Clin Cancer Res 2004;10:1753-7.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 1753-1757
-
-
Shinozaki, M.1
Fujimoto, A.2
Morton, D.L.3
-
15
-
-
27844567142
-
Distinct sets of genetic alterations in melanoma
-
Curtin JA, Fridlyand J, Kageshita T, et al. Distinct sets of genetic alterations in melanoma. N Engl J Med 2005;353:2135-47.
-
(2005)
N Engl J Med
, vol.353
, pp. 2135-2147
-
-
Curtin, J.A.1
Fridlyand, J.2
Kageshita, T.3
-
16
-
-
0032858487
-
Phase III multicenter randomized trial of the Dartmouth regimen versus dacarbazine in patients with metastatic melanoma
-
Chapman PB, Einhorn LH, Meyers ML, et al. Phase III multicenter randomized trial of the Dartmouth regimen versus dacarbazine in patients with metastatic melanoma. J Clin Oncol 1999;17:2745-51.
-
(1999)
J Clin Oncol
, vol.17
, pp. 2745-2751
-
-
Chapman, P.B.1
Einhorn, L.H.2
Meyers, M.L.3
-
17
-
-
79958783120
-
Extended schedule, escalated dose temozolomide versus dacarbazine in stage IV melanoma: final results of a randomised phase III study (EORTC 18032)
-
Patel PM, Suciu S, Mortier L, et al. Extended schedule, escalated dose temozolomide versus dacarbazine in stage IV melanoma: final results of a randomised phase III study (EORTC 18032). Eur J Cancer 2011;47:1476-83.
-
(2011)
Eur J Cancer
, vol.47
, pp. 1476-1483
-
-
Patel, P.M.1
Suciu, S.2
Mortier, L.3
-
18
-
-
84863673204
-
Improved Survival with MEK inhibition in BRAF-mutated melanoma
-
Flaherty KT, Robert C, Hersey P, et al. Improved Survival with MEK inhibition in BRAF-mutated melanoma. N Engl J Med 2012;367:107-14.
-
(2012)
N Engl J Med
, vol.367
, pp. 107-114
-
-
Flaherty, K.T.1
Robert, C.2
Hersey, P.3
-
19
-
-
79959795786
-
Improved survival with vemurafenib in melanoma with BRAF V600E mutation
-
Chapman PB, Hauschild A, Robert C, et al. Improved survival with vemurafenib in melanoma with BRAF V600E mutation. N Engl J Med 2011;364:2507-16.
-
(2011)
N Engl J Med
, vol.364
, pp. 2507-2516
-
-
Chapman, P.B.1
Hauschild, A.2
Robert, C.3
-
20
-
-
84864285704
-
Dabrafenib in BRAF-mutated metastatic melanoma: a multicentre, open-label, phase 3 randomised controlled trial
-
Hauschild A, Grob JJ, Demidov LV, et al. Dabrafenib in BRAF-mutated metastatic melanoma: a multicentre, open-label, phase 3 randomised controlled trial. Lancet 2012;380:358-65.
-
(2012)
Lancet
, vol.380
, pp. 358-365
-
-
Hauschild, A.1
Grob, J.J.2
Demidov, L.V.3
-
21
-
-
84875706825
-
Resistance to BRAF-targeted therapy in melanoma
-
Sullivan RJ, Flaherty KT. Resistance to BRAF-targeted therapy in melanoma. Eur J Cancer 2013;49:1297-304.
-
(2013)
Eur J Cancer
, vol.49
, pp. 1297-1304
-
-
Sullivan, R.J.1
Flaherty, K.T.2
-
22
-
-
34247337993
-
Detection of mutated BRAFV600E variant in circulating DNA of stage III-IV melanoma patients
-
Daniotti M, Vallacchi V, Rivoltini L, et al. Detection of mutated BRAFV600E variant in circulating DNA of stage III-IV melanoma patients. Int J Cancer 2007;120:2439-44.
-
(2007)
Int J Cancer
, vol.120
, pp. 2439-2444
-
-
Daniotti, M.1
Vallacchi, V.2
Rivoltini, L.3
-
23
-
-
34247537858
-
Utility of circulating B-RAF DNA mutation in serum for monitoring melanoma patients receiving biochemotherapy
-
Shinozaki M, O'Day SJ, Kitago M, et al. Utility of circulating B-RAF DNA mutation in serum for monitoring melanoma patients receiving biochemotherapy. Clin Cancer Res 2007;13:2068-74.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 2068-2074
-
-
Shinozaki, M.1
O'Day, S.J.2
Kitago, M.3
-
24
-
-
70449535638
-
Detection of BRAF mutations in the tumour and serum of patients enrolled in the AZD6244 (ARRY-142886) advanced melanoma phase II study
-
Board RE, Ellison G, Orr MC, et al. Detection of BRAF mutations in the tumour and serum of patients enrolled in the AZD6244 (ARRY-142886) advanced melanoma phase II study. Br J Cancer 2009;101:1724-30.
-
(2009)
Br J Cancer
, vol.101
, pp. 1724-1730
-
-
Board, R.E.1
Ellison, G.2
Orr, M.C.3
-
25
-
-
84898786810
-
Analytical validation of BRAF mutation testing from circulating free DNA using the amplification refractory mutation testing system
-
Aung KL, Donald E, Ellison G, et al. Analytical validation of BRAF mutation testing from circulating free DNA using the amplification refractory mutation testing system. J Mol Diagn 2014;16:343-9.
-
(2014)
J Mol Diagn
, vol.16
, pp. 343-349
-
-
Aung, K.L.1
Donald, E.2
Ellison, G.3
-
26
-
-
84891648456
-
Phase II trial (BREAK-2) of the BRAF inhibitor dabrafenib (GSK2118436) in patients with metastatic melanoma
-
Ascierto PA, Minor D, Ribas A, et al. Phase II trial (BREAK-2) of the BRAF inhibitor dabrafenib (GSK2118436) in patients with metastatic melanoma. J Clin Oncol 2013;31:3205-11.
-
(2013)
J Clin Oncol
, vol.31
, pp. 3205-3211
-
-
Ascierto, P.A.1
Minor, D.2
Ribas, A.3
-
27
-
-
84946499416
-
BRAF mutation analysis in circulating free tumor DNA of melanoma patients treated with BRAF inhibitors
-
Gonzalez-Cao M, Mayo-de-las-Casas C, Molina-Vila MA, et al. BRAF mutation analysis in circulating free tumor DNA of melanoma patients treated with BRAF inhibitors. Melanoma Res 2015;25:486-95.
-
(2015)
Melanoma Res
, vol.25
, pp. 486-495
-
-
Gonzalez-Cao, M.1
Mayo-de-las-Casas, C.2
Molina-Vila, M.A.3
-
28
-
-
84965092386
-
Association of EGFR L858R Mutation in Circulating Free DNA With Survival in the EURTAC Trial
-
Karachaliou N, Mayo-de las Casas C, Queralt C, et al. Association of EGFR L858R Mutation in Circulating Free DNA With Survival in the EURTAC Trial. JAMA Oncol 2015;1:149-57.
-
(2015)
JAMA Oncol
, vol.1
, pp. 149-157
-
-
Karachaliou, N.1
Mayo-de las Casas, C.2
Queralt, C.3
-
29
-
-
85015493604
-
BRAF mutation analysis in tumoral cell free DNA (cfDNA) of melanoma patients: preliminary results from the Spanish Melanoma Group prospective study GEM1304
-
Gonzalez-Cao M, Soriano V, Rodriguez D, et al. BRAF mutation analysis in tumoral cell free DNA (cfDNA) of melanoma patients: preliminary results from the Spanish Melanoma Group prospective study GEM1304. Annals Oncol 2014;25:iv384.
-
(2014)
Annals Oncol
, vol.25
, pp. iv384
-
-
Gonzalez-Cao, M.1
Soriano, V.2
Rodriguez, D.3
-
30
-
-
84918505173
-
Clinical utility of a blood-based BRAF(V600E) mutation assay in melanoma
-
Panka DJ, Buchbinder E, Giobbie-Hurder A, et al. Clinical utility of a blood-based BRAF(V600E) mutation assay in melanoma. Mol Cancer Ther 2014;13:3210-8.
-
(2014)
Mol Cancer Ther
, vol.13
, pp. 3210-3218
-
-
Panka, D.J.1
Buchbinder, E.2
Giobbie-Hurder, A.3
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