메뉴 건너뛰기




Volumn 12, Issue 2, 2017, Pages 403-407

Checkpoint Inhibitors in Metastatic EGFR-Mutated Non–Small Cell Lung Cancer—A Meta-Analysis

Author keywords

EGFR mutation; Immune checkpoint inhibitors; NSCLC; Predictive biomarker

Indexed keywords

ATEZOLIZUMAB; DOCETAXEL; EPIDERMAL GROWTH FACTOR RECEPTOR; NIVOLUMAB; PEMBROLIZUMAB; ANTINEOPLASTIC AGENT; EGFR PROTEIN, HUMAN;

EID: 85015330057     PISSN: 15560864     EISSN: 15561380     Source Type: Journal    
DOI: 10.1016/j.jtho.2016.10.007     Document Type: Article
Times cited : (689)

References (15)
  • 1
    • 79953118839 scopus 로고    scopus 로고
    • Genotypic and histological evolution of lung cancers acquiring resistance to EGFR inhibitors
    • 75ra26–75ra26
    • 1 Sequist, L.V., Waltman, B.A., Dias-Santagata, D., et al. Genotypic and histological evolution of lung cancers acquiring resistance to EGFR inhibitors. Sci Transl Med, 3, 2011 75ra26–75ra26.
    • (2011) Sci Transl Med , vol.3
    • Sequist, L.V.1    Waltman, B.A.2    Dias-Santagata, D.3
  • 2
    • 49649127657 scopus 로고    scopus 로고
    • Mechanisms of acquired resistance to epidermal growth factor receptor tyrosine kinase inhibitors in non–small cell lung cancer
    • 2 Engelman, J.A., Jänne, P.A., Mechanisms of acquired resistance to epidermal growth factor receptor tyrosine kinase inhibitors in non–small cell lung cancer. Clin Cancer Res 14 (2008), 2895–2899.
    • (2008) Clin Cancer Res , vol.14 , pp. 2895-2899
    • Engelman, J.A.1    Jänne, P.A.2
  • 3
    • 34249075147 scopus 로고    scopus 로고
    • MET Amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling
    • 3 Engelman, J.A., Zejnullahu, K., Mitsudomi, T., et al. MET Amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling. Science 316 (2007), 1039–1043.
    • (2007) Science , vol.316 , pp. 1039-1043
    • Engelman, J.A.1    Zejnullahu, K.2    Mitsudomi, T.3
  • 4
    • 84867760241 scopus 로고    scopus 로고
    • HER2 amplification: a potential mechanism of acquired resistance to EGFR inhibition in EGFR-mutant lung cancers that lack the second-site EGFRT790M mutation
    • 4 Takezawa, K., Pirazzoli, V., Arcila, M.E., et al. HER2 amplification: a potential mechanism of acquired resistance to EGFR inhibition in EGFR-mutant lung cancers that lack the second-site EGFRT790M mutation. Cancer Discov 2 (2012), 922–933.
    • (2012) Cancer Discov , vol.2 , pp. 922-933
    • Takezawa, K.1    Pirazzoli, V.2    Arcila, M.E.3
  • 5
    • 84928739294 scopus 로고    scopus 로고
    • AZD9291 in EGFR inhibitor–resistant non–small-cell lung cancer
    • 5 Jänne, P.A., Yang, J.C.-H., Kim, D.-W., et al. AZD9291 in EGFR inhibitor–resistant non–small-cell lung cancer. N Engl J Med 372 (2015), 1689–1699.
    • (2015) N Engl J Med , vol.372 , pp. 1689-1699
    • Jänne, P.A.1    Yang, J.C.-H.2    Kim, D.-W.3
  • 6
    • 84944937210 scopus 로고    scopus 로고
    • Nivolumab versus docetaxel in advanced nonsquamous non–small-cell lung cancer
    • 6 Borghaei, H., Paz-Ares, L., Horn, L., et al. Nivolumab versus docetaxel in advanced nonsquamous non–small-cell lung cancer. N Engl J Med 373 (2015), 1627–1639.
    • (2015) N Engl J Med , vol.373 , pp. 1627-1639
    • Borghaei, H.1    Paz-Ares, L.2    Horn, L.3
  • 7
    • 84950117835 scopus 로고    scopus 로고
    • Pembrolizumab versus docetaxel for previously treated, PD-L1-positive, advanced non-small-cell lung cancer (KEYNOTE-010): a randomised controlled trial
    • 7 Herbst, R.S., Baas, P., Kim, D.-W., et al. Pembrolizumab versus docetaxel for previously treated, PD-L1-positive, advanced non-small-cell lung cancer (KEYNOTE-010): a randomised controlled trial. Lancet 387 (2015), 1540–1550.
    • (2015) Lancet , vol.387 , pp. 1540-1550
    • Herbst, R.S.1    Baas, P.2    Kim, D.-W.3
  • 8
    • 84890020587 scopus 로고    scopus 로고
    • Activation of the PD-1 pathway contributes to immune escape in EGFR-driven lung tumors
    • 8 Akbay, E.A., Koyama, S., Carretero, J., et al. Activation of the PD-1 pathway contributes to immune escape in EGFR-driven lung tumors. Cancer Discov 3 (2013), 1355–1363.
    • (2013) Cancer Discov , vol.3 , pp. 1355-1363
    • Akbay, E.A.1    Koyama, S.2    Carretero, J.3
  • 9
    • 84990938506 scopus 로고    scopus 로고
    • EGFR mutations and ALK rearrangements are associated with low response rates to PD-1 pathway blockade in non-small cell lung cancer (NSCLC): a retrospective analysis
    • 9 Gainor, J.F., Shaw, A.T., Sequist, L.V., et al. EGFR mutations and ALK rearrangements are associated with low response rates to PD-1 pathway blockade in non-small cell lung cancer (NSCLC): a retrospective analysis. Clin Cancer Res 22 (2016), 4585–4593.
    • (2016) Clin Cancer Res , vol.22 , pp. 4585-4593
    • Gainor, J.F.1    Shaw, A.T.2    Sequist, L.V.3
  • 10
    • 84984708502 scopus 로고    scopus 로고
    • Updated survival and biomarker analyses of a randomized phase II study of atezolizumab vs. docetaxel in 2L/3L NSCLC (POPLAR)
    • [abstract]
    • 10 Smith, D.A., Vansteenkiste, J.F., Fehrenbacher, L., et al. Updated survival and biomarker analyses of a randomized phase II study of atezolizumab vs. docetaxel in 2L/3L NSCLC (POPLAR). [abstract] J Clin Oncol, 34(suppl), 2016, 9028.
    • (2016) J Clin Oncol , vol.34 , pp. 9028
    • Smith, D.A.1    Vansteenkiste, J.F.2    Fehrenbacher, L.3
  • 11
    • 84962038946 scopus 로고    scopus 로고
    • Atezolizumab versus docetaxel for patients with previously treated non-small-cell lung cancer (POPLAR): a multicentre, open-label, phase 2 randomised controlled trial
    • 11 Fehrenbacher, L., Spira, A., Ballinger, M., et al. Atezolizumab versus docetaxel for patients with previously treated non-small-cell lung cancer (POPLAR): a multicentre, open-label, phase 2 randomised controlled trial. Lancet 387 (2016), 1837–1846.
    • (2016) Lancet , vol.387 , pp. 1837-1846
    • Fehrenbacher, L.1    Spira, A.2    Ballinger, M.3
  • 12
    • 84984686125 scopus 로고    scopus 로고
    • Long-term OS for patients with advanced NSCLC enrolled in the KEYNOTE-001 study of pembrolizumab (pembro)
    • [abstract]
    • 12 Hui, R., Gandhi, L., Carcereny Costa, E., et al. Long-term OS for patients with advanced NSCLC enrolled in the KEYNOTE-001 study of pembrolizumab (pembro). [abstract] J Clin Oncol, 34(suppl), 2016, 9026.
    • (2016) J Clin Oncol , vol.34 , pp. 9026
    • Hui, R.1    Gandhi, L.2    Carcereny Costa, E.3
  • 13
    • 84928761118 scopus 로고    scopus 로고
    • Mutational landscape determines sensitivity to PD-1 blockade in non–small cell lung cancer
    • 13 Rizvi, N.A., Hellmann, M.D., Snyder, A., et al. Mutational landscape determines sensitivity to PD-1 blockade in non–small cell lung cancer. Science 348 (2015), 125–128.
    • (2015) Science , vol.348 , pp. 125-128
    • Rizvi, N.A.1    Hellmann, M.D.2    Snyder, A.3
  • 14
    • 84979213912 scopus 로고    scopus 로고
    • Total mutation burden (TMB) in lung cancer (LC) and relationship with response to PD-1/PD-L1 targeted therapies
    • [abstract]
    • 14 Spigel, D.R., Schrock, A.B., Fabrizio, D., et al. Total mutation burden (TMB) in lung cancer (LC) and relationship with response to PD-1/PD-L1 targeted therapies. [abstract] J Clin Oncol, 34(suppl), 2016, 9017.
    • (2016) J Clin Oncol , vol.34 , pp. 9017
    • Spigel, D.R.1    Schrock, A.B.2    Fabrizio, D.3
  • 15
    • 84984681480 scopus 로고    scopus 로고
    • CheckMate 012: safety and efficacy of first-line (1L) nivolumab (nivo; N) and ipilimumab (ipi; I) in advanced (adv) NSCLC
    • [abstract]
    • 15 Hellmann, M.D., Gettinger, S.N., Goldman, J.W., et al. CheckMate 012: safety and efficacy of first-line (1L) nivolumab (nivo; N) and ipilimumab (ipi; I) in advanced (adv) NSCLC. [abstract] J Clin Oncol, 34(suppl), 2016, 3001.
    • (2016) J Clin Oncol , vol.34 , pp. 3001
    • Hellmann, M.D.1    Gettinger, S.N.2    Goldman, J.W.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.