Machine-learning algorithms define pathogen-specific local immune fingerprints in peritoneal dialysis patients with bacterial infections

Kidney International

Volumn 92, Issue 1, 2017, Pages 179-191

  Zhang, Jingjing ^a   Friberg, Ida M ^a,g   Kift Morgan, Ann ^a   Parekh, Gita ^b   Morgan, Matt P ^a,c   Liuzzi, Anna Rita ^a   Lin, Chan Yu ^a,d   Donovan, Kieron L ^c,e   Colmont, Chantal S ^e   Morgan, Peter H ^f   Davis, Paul ^b   Weeks, Ian ^a   Fraser, Donald J ^a,c,e   Topley, Nicholas ^a,e   Eberl, Matthias ^a  

^a CARDIFF UNIVERSITY   (United Kingdom)

^b Mologic Ltd   (United Kingdom)

^c UNIVERSITY HOSPITAL OF WALES   (United Kingdom)

^d CHANG GUNG UNIVERSITY COLLEGE OF MEDICINE   (Taiwan)

^e Heath Park   (United Kingdom)

^f CARDIFF UNIVERSITY   (United Kingdom)

^g UNIVERSITY OF SALFORD   (United Kingdom)

Author keywords

biomarkers; inflammation; machine learning methods; microbial infection; peritoneal dialysis

Indexed keywords

CHEMOKINE; CYTOKINE; BIOLOGICAL MARKER;

ADULT; AGED; ALGORITHM; ARTICLE; BACTERIAL INFECTION; COAGULASE NEGATIVE STAPHYLOCOCCUS; EFFLUENT; FEMALE; GRAM NEGATIVE BACTERIUM; GRAM NEGATIVE INFECTION; GRAM POSITIVE BACTERIUM; GRAM POSITIVE INFECTION; HEMODIALYSIS PATIENT; HUMAN; IMMUNE RESPONSE; IMMUNE SYSTEM; IMMUNOCOMPETENT CELL; MACHINE LEARNING; MAJOR CLINICAL STUDY; MALE; MATHEMATICAL MODEL; PERITONEAL DIALYSIS; PERITONITIS; PRIORITY JOURNAL; STREPTOCOCCUS; VERY ELDERLY; ACUTE DISEASE; ADOLESCENT; AREA UNDER THE CURVE; AUTOMATED PATTERN RECOGNITION; BACTERIUM; CASE CONTROL STUDY; CLASSIFICATION; COMPARATIVE STUDY; HOST PATHOGEN INTERACTION; IMMUNOLOGY; METABOLISM; MICROBIOLOGY; MIDDLE AGED; NONLINEAR SYSTEM; PATHOGENICITY; PEPTIDE MAPPING; POINT OF CARE SYSTEM; POINT OF CARE TESTING; PREDICTIVE VALUE; PROCEDURES; RECEIVER OPERATING CHARACTERISTIC; REPRODUCIBILITY; TIME FACTOR; YOUNG ADULT;

ACUTE DISEASE; ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; AREA UNDER CURVE; BACTERIA; BIOMARKERS; CASE-CONTROL STUDIES; FEMALE; GRAM-NEGATIVE BACTERIAL INFECTIONS; GRAM-POSITIVE BACTERIAL INFECTIONS; HOST-PATHOGEN INTERACTIONS; HUMANS; MACHINE LEARNING; MALE; MIDDLE AGED; NONLINEAR DYNAMICS; PATTERN RECOGNITION, AUTOMATED; PEPTIDE MAPPING; PERITONEAL DIALYSIS; PERITONITIS; POINT-OF-CARE SYSTEMS; POINT-OF-CARE TESTING; PREDICTIVE VALUE OF TESTS; REPRODUCIBILITY OF RESULTS; ROC CURVE; TIME FACTORS; YOUNG ADULT;

EID: 85015297808     PISSN: 00852538     EISSN: 15231755     Source Type: Journal    
DOI: 10.1016/j.kint.2017.01.017     Document Type: Article

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