Short-lived recombinant adeno-associated virus transgene expression in dystrophic muscle is associated with oxidative damage to transgene mRNA

Molecular Therapy Methods and Clinical Development

Volumn 2, Issue , 2015, Pages 15010-

  Dupont, Jean Baptiste ^a,b,c   Tournaire, Benoit ^a,b,c   Georger, Christophe ^d   Marolleau, Béatrice ^d   Jeanson Leh, Laurence ^d   Ledevin, Mireille ^e   Lindenbaum, Pierre ^b,c,f   Lecomte, Emilie ^a,b,c   Cogné, Benjamin ^a,b,c   Dubreil, Laurence ^e   Larcher, Thibaut ^e   Gjata, Bernard ^d   Van Wittenberghe, Laetitia ^d   Le Guiner, Caroline ^a,b,c,d   Penaud Budloo, Magalie ^a,b,c   Snyder, Richard O ^a,g   Moullier, Philippe ^a,b,c,g   Léger, Adrien ^a,b,c  

^a UNIVERSITÉ DE NANTES   (France)

^b UNIVERSITÉ DE NANTES   (France)

^c NANTES UNIVERSITY HOSPITAL   (France)

^d GÉNÉTHON   (France)

^e LUNAM UNIVERSITÉ   (France)

^f L INSTITUT DU THORAX   (France)

^g UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; ADENO ASSOCIATED VIRUS VECTOR;

ADENO ASSOCIATED VIRUS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DUCHENNE MUSCULAR DYSTROPHY; EPIGENETICS; GENE SILENCING; MOUSE; MUSCULAR DYSTROPHY; NONHUMAN; OXIDATION; OXIDATIVE STRESS; PATHOPHYSIOLOGY; PRIORITY JOURNAL; TRANSGENE; VIRUS GENE; VIRUS GENOME; ANIMAL TISSUE; CANINE MODEL; GENE EXPRESSION; GENE VECTOR; MOUSE MODEL; POSTTRANSCRIPTIONAL GENE SILENCING;

EID: 85015224577     PISSN: None     EISSN: 23290501     Source Type: Journal    
DOI: 10.1038/mtm.2015.10     Document Type: Article

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