Oxidative damage in muscular dystrophy correlates with the severity of the pathology: Role of glutathione metabolism

Neurochemical Research

Volumn 37, Issue 4, 2012, Pages 885-898

  Renjini, R ^a   Gayathri, N ^a   Nalini, A ^a   Bharath, M M Srinivas ^a  

^a NATIONAL INSTITUTE OF MENTAL HEALTH AND NEUROSCIENCES   (India)

Author keywords

Cardiotoxin; Duchenne muscular dystrophy; Dysferlinopathy; Glutathione; Muscular dystrophy; Oxidative stress; Sarcoglycanopathy

Indexed keywords

CARDIOTOXIN; GLUTAMATE CYSTEINE LIGASE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE TRANSFERASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; BIOSYNTHESIS; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE EXACERBATION; DISEASE MARKER; DISEASE SEVERITY; DUCHENNE MUSCULAR DYSTROPHY; DYSFERLINOPATHY; ENZYME ACTIVITY; FEMALE; HUMAN; HUMAN TISSUE; LIPID OXIDATION; MALE; MOUSE; MUSCLE BIOPSY; MYOBLAST; NEUROPATHOLOGY; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN METABOLISM; SARCOGLYCANOPATHY;

ADOLESCENT; ADULT; ANIMALS; CELL LINE; CHILD; CHILD, PRESCHOOL; FEMALE; GLUTATHIONE; HUMANS; MALE; MICE; MUSCULAR DYSTROPHIES; OXIDATION-REDUCTION; OXIDATIVE STRESS; SEVERITY OF ILLNESS INDEX; YOUNG ADULT;

EID: 84862834965     PISSN: 03643190     EISSN: 15736903     Source Type: Journal    
DOI: 10.1007/s11064-011-0683-z     Document Type: Article

References (52)

1. Dubowitz V, Sewry CA (2007) Muscle biopsy-A practical approach, 3rd edn. Saunders Elsevier, London
2. Munoz P, Rosemblatt M, Testar X, Palacin M, Zorzano A (1995) Isolation and characterization of distinct domains of sarcolemma and T-tubules from rat skeletal muscle. Biochem J 307(Pt 1): 273-280
3. Rando TA (2001) The dystrophin-glycoprotein complex, cellular signaling, and the regulation of cell survival in the muscular dystrophies. Muscle Nerve 24(12):1575-1594 (Pubitemid 33101403)
4. Emery AEH (1999) Neuromuscular disorders: clinical and molecular genetics. Wiley, England
5. Burr IM, Asayama K, Fenichel GM (1987) Superoxide dismutases, glutathione peroxidase, and catalase in neuromuscular disease. Muscle Nerve 10(2):150-154. doi:10.1002/mus.880100208 (Pubitemid 17004219)
6. Kar NC, Pearson CM (1979) Catalase, superoxide dismutase, glutathione reductase and thiobarbituric acid-reactive products in normal and dystrophic human muscle. Clin Chim Acta 94(3): 277-280 (Pubitemid 9204033)
7. Jongpiputvanich S, Sueblinvong T, Norapucsunton T (2005) Mitochondrial respiratory chain dysfunction in various neuromuscular diseases. J Clin Neurosci 12(4):426-428. doi:10.1016/j.jocn.2004.06.014 (Pubitemid 40745228)
8. Haslbeck KM, Friess U, Schleicher ED, Bierhaus A, Nawroth PP, Kirchner A, Pauli E, Neundorfer B, Heuss D (2005) The RAGE pathway in inflammatory myopathies and limb girdle muscular dystrophy. Acta Neuropathol 110(3):247-254. doi:10.1007/s00401-005-1043-3 (Pubitemid 41430653)
9. Burri BJ, Chan SG, Berry AJ, Yarnell SK (1980) Blood levels of superoxide dismutase and glutathione peroxidase in Duchenne muscular dystrophy. Clin Chim Acta 105(2):249-255 (Pubitemid 10078348)
10. Grosso S, Perrone S, Longini M, Bruno C, Minetti C, Gazzolo D, Balestri P, Buonocore G (2008) Isoprostanes in dystrophinopathy: evidence of increased oxidative stress. Brain Dev 30(6): 391-395. doi:10.1016/j.braindev.2007.11.005 (Pubitemid 351602223)
11. Haycock JW, Mac Neil S, Mantle D (1998) Differential protein oxidation in Duchenne and Becker muscular dystrophy. Neuro Report 9(10):2201-2207 (Pubitemid 28338206)
12. Nakae Y, Stoward PJ, Kashiyama T, Shono M, Akagi A, Matsuzaki T, Nonaka I (2004) Early onset of lipofuscin accumulation in dystrophin-deficient skeletal muscles of DMD patients and mdx mice. J Mol Histol 35(5):489-499 (Pubitemid 41410964)
13. Dudley RW, Khairallah M, Mohammed S, Lands L, Des Rosiers C, Petrof BJ (2006) Dynamic responses of the glutathione system to acute oxidative stress in dystrophic mouse (mdx) muscles. Am J Physiol Regul Integr Comp Physiol 291(3):704-710. doi: 10.1152/ajpregu.00031.2006 (Pubitemid 44352353)
14. Ragusa RJ, Chow CK, Porter JD (1997) Oxidative stress as a potential pathogenic mechanism in an animal model of Duchenne muscular dystrophy. Neuromuscul Disord 7(6-7):379-386 (Pubitemid 27445322)
15. Dudley RW, Danialou G, Govindaraju K, Lands L, Eidelman DE, Petrof BJ (2006) Sarcolemmal damage in dystrophin deficiency is modulated by synergistic interactions between mechanical and oxidative/nitrosative stresses. Am J Pathol 168(4): 1276-1287; quiz 1404-1275. doi:10.2353/ajpath.2006.050683
16. Murphy ME, Kehrer JP (1986) Activities of antioxidant enzymes in muscle, liver and lung of chickens with inherited muscular dystrophy. Biochem Biophys Res Commun 134(2):550-556 (Pubitemid 16070533)
17. Salminen A, Kihlstrom M (1989) Increased susceptibility to lipid peroxidation in skeletal muscles of dystrophic hamsters. Experientia 45(8):747-749 (Pubitemid 19198322)
18. Bradford MM (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72:248-254
19. Renjini R, Gayathri N, Nalini A, Srinivas Bharath MM (2011) Analysis of Calpain 3 protein in muscle biopsies of different muscular dystrophies from India. Indian J Med Res (in press)
20. Hsu DK, Guo Y, Alberts GF, Copeland NG, Gilbert DJ, Jenkins NA, Peifley KA, Winkles JA (1996) Identification of a murine TEF-1-related gene expressed after mitogenic stimulation of quiescent fibroblasts and during myogenic differentiation. J Biol Chem 271(23):13786-13795 (Pubitemid 26187990)
21. Ardite E, Barbera JA, Roca J, Fernandez-Checa JC (2004) Glutathione depletion impairs myogenic differentiation of murine skeletal muscle C2C12 cells through sustained NF-kappaB activation. Am J Pathol 165(3):719-728 (Pubitemid 39129280)
22. Vali S, Mythri RB, Jagatha B, Padiadpu J, Ramanujan KS, Andersen JK, Gorin F, Bharath MM (2007) Integrating glutathione metabolism and mitochondrial dysfunction with implications for Parkinson's disease: a dynamic model. Neuroscience 149(4):917-930. doi:10.1016/j.neuroscience.2007.08.028 (Pubitemid 350130291)
23. Ohashi T, Kakimoto K, Sokawa Y, Taketani S (2002) Semiquantitative estimation of heme/hemoprotein with dichlorodihy-drofluorescin diacetate. Anal Biochem 308(2):392-395 (Pubitemid 35177155)
24. Harish G, Venkateshappa C, Mythri RB, Dubey SK, Mishra K, Singh N, Vali S, Bharath MM (2010) Bioconjugates of curcumin display improved protection against glutathione depletion mediated oxidative stress in a dopaminergic neuronal cell line: implications for Parkinson's disease. Bioorg Med Chem 18(7):2631-2638. doi:10.1016/j.bmc.2010.02.029
25. Kherif S, Lafuma C, Dehaupas M, Lachkar S, Fournier JG, Verdiere-Sahuque M, Fardeau M, Alameddine HS (1999) Expression of matrix metalloproteinases 2 and 9 in regenerating skeletal muscle: a study in experimentally injured and mdx muscles. Dev Biol 205(1):158-170. doi:10.1006/dbio.1998.9107 (Pubitemid 29042665)
26. Ohkawa H, Ohishi N, Yagi K (1979) Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem 95(2):351-358 (Pubitemid 9194347)
27. Mythri RB, Venkateshappa C, Harish G, Mahadevan A, Muthane UB, Yasha TC, Srinivas Bharath MM, Shankar SK (2011) Evaluation of markers of oxidative stress, antioxidant function and astrocytic proliferation in the striatum and frontal cortex of Parkinson's disease brains. Neurochem Res 36(8):1452-1463. doi:10.1007/s11064-011-0471-9
28. Levine RL, Garland D, Oliver CN, Amici A, Climent I, Lenz AG, Ahn BW, Shaltiel S, Stadtman ER (1990) Determination of carbonyl content in oxidatively modified proteins. Methods Enzymol 186:464-478 (Pubitemid 20279989)
29. Mythri RB, Jagatha B, Pradhan N, Andersen J, Bharath MM (2007) Mitochondrial complex I inhibition in Parkinson's disease: how can curcumin protect mitochondria? Antioxid Redox Signal 9(3):399-408. doi:10.1089/ars.2007. 9.ft-25 (Pubitemid 46145986)
30. Sambrook J, Russell DW (2001) Molecular cloning, a laboratory manual, 3rd ed edn. Cold spring Harbor Laboratory Press, New York
31. Bagnyukova TV, Storey KB, Lushchak VI (2003) Induction of oxidative stress in Rana ridibunda during recovery from winter hibernation. J Therm Biol 28(1):21-28. doi:10.1016/s0306-4565(02)00031-1 (Pubitemid 36164273)
32. Aebi H (1984) Catalase in vitro. Methods Enzymol 105:121-126
33. Flohe L, Gunzler WA (1984) Assays of glutathione peroxidase. Methods Enzymol 105:114-121 (Pubitemid 14165378)
34. Carlberg I, Mannervik B (1985) Glutathione reductase. Methods Enzymol 113:484-490 (Pubitemid 16195819)
35. Guthenberg C, Alin P, Mannervik B (1985) Glutathione transferase from rat testis. Methods Enzymol 113:507-510 (Pubitemid 16195824)
36. Seelig GF, Meister A (1985) Glutathione biosynthesis; gamma-glutamylcysteine synthetase from rat kidney. Methods Enzymol 113:379-390 (Pubitemid 16195807)
37. Hill KE, McCollum GW, Burk RF (1997) Determination of thioredoxin reductase activity in rat liver supernatant. Anal Biochem 253(1):123-125. doi:10.1006/abio.1997.2373 (Pubitemid 27490613)
38. Brancaccio P, Lippi G, Maffulli N (2010) Biochemical markers of muscular damage. Clin Chem Lab Med 48(6):757-767. doi: 10.1515/cclm.2010.179
39. Degl'Innocenti D, Rosati F, Iantomasi T, Vincenzini MT, Ramponi G (1999) GSH system in relation to redox state in dystrophic skin fibroblasts. Biochimie 81(11):1025-1029
40. Khouzami L, Bourin MC, Christov C, Damy T, Escoubet B, Caramelle P, Perier M, Wahbi K, Meune C, Pavoine C, Pecker F (2010) Delayed cardiomyopathy in dystrophin deficient mdx mice relies on intrinsic glutathione resource. Am J Pathol 177(3):1356-1364. doi:10.2353/ajpath.2010.090479
41. Spassov A, Gredes T, Gedrange T, Pavlovic D, Lupp A, Kunert-Keil C (2010) Increased oxidative stress in dystrophin deficient (mdx) mice masticatory muscles. Exp Toxicol Pathol. doi: 10.1016/j.etp.2010.04.006
42. Jackson MJ (2008) Redox regulation of skeletal muscle. IUBMB Life 60(8):497-501. doi:10.1002/iub.72
43. Dorchies OM, Wagner S, Buetler TM, Ruegg UT (2009) Protection of dystrophic muscle cells with polyphenols from green tea correlates with improved glutathione balance and increased expression of 67LR, a receptor for (-)-epigallocatechin gallate. Biofactors 35(3):279-294. doi:10.1002/biof.34
44. Jackson MJ, Brooke MH, Kaiser K, Edwards RH (1991) Glutathione depletion during experimental damage to rat skeletal muscle and its relevance to Duchenne muscular dystrophy. Clin Sci (Lond) 80(6):559-564
45. Lesgards JF, Gauthier C, Iovanna J, Vidal N, Dolla A, Stocker P (2011) Effect of reactive oxygen and carbonyl species on crucial cellular antioxidant enzymes. Chem Biol Interact 190(1):28-34. doi:10.1016/j.cbi.2010.12.028
46. Kramerova I, Kudryashova E, Wu B, Germain S, Vandenborne K, Romain N, Haller RG, Verity MA, Spencer MJ (2009) Mitochondrial abnormalities, energy deficit and oxidative stress are features of calpain 3 deficiency in skeletal muscle. Hum Mol Genet 18(17):3194-3205. doi:10.1093/hmg/ddp257
47. Dioszeghy P, Imre S, Mechler F (1989) Lipid peroxidation and superoxide dismutase activity in muscle and erythrocytes in adult muscular dystrophies and neurogenic atrophies. Eur Arch Psychiatry Neurol Sci 238(3):175-177 (Pubitemid 19097635)
48. Potgieter M, Pretorius E, Van der Merwe CF, Beukes M, Vieira WA, Auer RE, Auer M, Meyer S (2011) Histological assessment of SJL/J mice treated with the antioxidants coenzyme Q10 and resveratrol. Micron 42(3):275-282. doi:10.1016/j.micron.2010.10.001
49. Bharath S, Hsu M, Kaur D, Rajagopalan S, Andersen JK (2002) Glutathione, iron and Parkinson's disease. Biochem Pharmacol 64(5-6):1037-1048 (Pubitemid 35232279)
50. Tidball JG, Wehling-Henricks M (2007) The role of free radicals in the pathophysiology of muscular dystrophy. J Appl Physiol 102(4):1677-1686 (Pubitemid 46571068)
51. Vidal B, Serrano AL, Tjwa M, Suelves M, Ardite E, De Mori R, Baeza-Raja B, Martinez de Lagran M, Lafuste P, Ruiz-Bonilla V, Jardi M, Gherardi R, Christov C, Dierssen M, Carmeliet P, Degen JL, Dewerchin M, Munoz-Canoves P (2008) Fibrinogen drives dystrophic muscle fibrosis via a TGFbeta/alternative macrophage activation pathway. Genes Dev 22(13):1747-1752. doi:10.1101/gad. 465908 (Pubitemid 351915499)
52. Yuasa K, Hagiwara Y, Ando M, Nakamura A, Takeda S, Hijikata T (2008) MicroRNA-206 is highly expressed in newly formed muscle fibers: implications regarding potential for muscle regeneration and maturation in muscular dystrophy. Cell Struct Funct 33(2):163-169