Impaired social and role function in ultra-high risk for psychosis and first-episode schizophrenia: Its relations with negative symptoms

Psychiatry Investigation

Volumn 14, Issue 2, 2017, Pages 186-192

  Lee, So Jung ^a   Kim, Kyung Ran ^a,b   Lee, Su Young ^b,c   An, Suk Kyoon ^a,b,d  

^a Yonsei University College of Medicine   (South Korea)

^b Yonsei University College of Medicine   (South Korea)

^c Dankook University College of Medicine   (South Korea)

^d Yonsei University   (South Korea)

Author keywords

First episode; Role dysfunction; Schizophrenia; Social dysfunction; Ultra high risk

Indexed keywords

ADULT; APATHY; ARTICLE; CONTROLLED STUDY; DEPRESSION; DEPRESSION ASSESSMENT; FEMALE; GLOBAL ASSESSMENT OF FUNCTIONING; HUMAN; MAJOR CLINICAL STUDY; MALE; MENTAL DISEASE; MONTGOMERY ASBERG DEPRESSION RATING SCALE; NEGATIVE SYNDROME; PSYCHOSIS; SCHIZOPHRENIA; SCORING SYSTEM; SOCIAL DISABILITY; YOUNG ADULT;

EID: 85015176933     PISSN: 17383684     EISSN: 19763026     Source Type: Journal    
DOI: 10.4306/pi.2017.14.2.186     Document Type: Article

References (37)

1. American Psychiatric Association. DSM-5: Diagnostic and Statistical Manual of Mental Disorders, 5th Edition. Washington, DC: American Psychiatric Publishing; 2013.
2. Yung AR, Phillips LJ, Yuen HP, Francey SM, McFarlane CA, Hallgren M, et al. Psychosis prediction: 12-month follow up of a high-risk (“prodromal”) group. Schizophr Res 2003;60:21-32.
3. Yung AR, Phillips LJ, Yuen HP, McGorry PD. Risk factors for psychosis in an ultra high-risk group: Psychopathology and clinical features. Schizophr Res 2004;67:131-142.
4. Velthorst E, Nelson B, Wiltink S, de Haan L, Wood SJ, Lin A, et al. Transition to first episode psychosis in ultra high risk populations: does baseline functioning hold the key?. Schizophr Res 2013;143:132-137.
5. Valmaggia LR, Stahl D, Yung AR, Nelson B, Fusar-Poli P, McGorry PD, et al. Negative psychotic symptoms and impaired role functioning predict transition outcomes in the at-risk mental state: a latent class cluster analysis study. Psychol Med 2013;43:2311-2325.
6. Addington J, van Mastrigt S, Addington D. Patterns of premorbid functioning in first-episode psychosis: initial presentation. Schizophr Res 2003;62:23-30.
7. Rapoport JL, Addington AM, Frangou S, Psych MR. The neurodevel-opmental model of schizophrenia: update 2005. Mol Psychiatry 2005;10: 434-449.
8. Addington J, Penn D, Woods SW, Addington D, Perkins DO. Social functioning in individuals at clinical high-risk for psychosis. Schizophr Res 2008;99:119-124.
9. Cannon TD, Cadenhead K, Cornblatt B, Woods SW, Addington J, Walker E, et al. Prediction of psychosis in youth at high clinical risk: a multisite longitudinal study in North America. Arch Gen Psychiatry 2008;65:28-37.
10. Perlick DA, Rosenheck RA, Kaczynski R, Bingham S, Collins J. Association of symptomatology and cognitive deficits to functional capacity in schizophrenia. Schizophr Res 2008;99:192-199.
11. Yamauchi K, Aki H, Tomotake M, Iga J, Numata S, Motoki I, et al. Predictors of subjective and objective quality of life in outpatients with schizophrenia. Psychiatry Clin Neurosci 2008;62:404-411.
12. Woon PS, Chia MY, Chan WY, Sim K. Neurocognitive, clinical and functional correlates of subjective quality of life in Asian outpatients with schizophrenia. Prog Neuropsychopharmacol Biol Psychiatry 2010;34:463-468.
13. Narvaez JM, Twamley EW, McKibbin CL, Heaton RK, Patterson TL. Subjective and objective quality of life in schizophrenia. Schizophr Res 2008;98:201-208.
14. Mohamed S, Rosenheck R, Swartz M, Stroup S, Lieberman JA, Keefe RS. Relationship of cognition and psychopathology to functional impairment in schizophrenia. Am J Psychiatry 2008;165:978-987.
15. Stouten LH, Veling W, Laan W, van der Helm M, van der Gaag M. Psychotic symptoms, cognition and affect as predictors of psychosocial problems and functional change in first-episode psychosis. Schizophr Res 2014;158:113-119.
16. Strauss GP, Sandt AR, Catalano LT, Allen DN. Negative symptoms and depression predict lower psychological well-being in individuals with schizophrenia. Compr Psychiatry 2012;53:1137-1144.
17. Rabinowitz J, Levine SZ, Garibaldi G, Bugarski-Kirola D, Berardo CG, Kapur S. Negative symptoms have greater impact on functioning than positive symptoms in schizophrenia: analysis of CATIE data. Schizophr Res 2012;137:147-150.
18. Hunter R, Barry S. Negative symptoms and psychosocial functioning in schizophrenia: neglected but important targets for treatment. Eur Psychiatry 2012;27:432-436.
19. Song YY, Kim KR, Park JY, Lee SY, Kang JI, Lee E, et al. Associated factors of quality of life in first-episode schizophrenia patients. Psychiatry Investig 2011;8:201-206.
20. Rocca P, Bellino S, Calvarese P, Marchiaro L, Patria L, Rasetti R. et al. Depressive and negative symptoms in schizophrenia: different effects on clinical features. Compr Psychiatry 2005;46:304-310.
21. Masillo A, Valmaggia LR, Saba R, Brandizzi M, Lindau JF, Solfanelli A, et al. Interpersonal sensitivity and functioning impairment in youth at ultra-high risk for psychosis. Eur Child Adolesc Psychiatry 2016;25:7-16.
22. Svirskis T, Korkeila J, Heinimaa M, Huttunen J, Ilonen T, Ristkari T, et al. Quality of life and functioning ability in subjects vulnerable to psy- chosis. Compr Psychiatry 2007;48:155-160.
23. Schlosser DA, Campellone TR, Biagianti B, Delucchi KL, Gard DE, Fulford D, et al. Modeling the role of negative symptoms in determining social functioning in individuals at clinical high risk of psychosis. Schizophr Res 2015;169:204-208.
24. Kim KR, Song YY, Park JY, Lee EH, Lee M, Lee SY, et al. The relationship between psychosocial functioning and resilience and negative symptoms in individuals at ultra-high risk for psychosis. Aust N Z J Psychiatry 2013;47:762-771.
25. Corcoran CM, Kimhy D, Parrilla-Escobar MA, Cressman VL, Stanford AD, Thompson J, et al. The relationship of social function to depressive and negative symptoms in individuals at clinical high risk for psychosis. Psychol Med 2011;41:251-261.
26. Ruhrmann S, Paruch J, Bechdolf A, Pukrop R, Wagner M, Berning J, et al. Reduced subjective quality of life in persons at risk for psychosis. Acta Psychiatr Scand 2008;117:357-368.
27. Olvet DM, Carrión RE, Auther AM, Cornblatt BA. Self-awareness of functional impairment in individuals at clinical high-risk for psychosis. Early Interv Psychiatry 2015;9:100-107.
28. First MB, Gibbon M, Spitzer RL, Williams JB. Structured Clinical Interview for DSM-IV Axis I Disorders: Non-Patients Edition (SCID-I/ NP). New York: Biometrics Research, New York State Psychiatric Institute; 2002.
29. First MB, Gibbon M, Spitzer RL, Williams JB. Structured Clinical Interview for DSM-IV Axis I Disorders: Patient Edition (SCID-I/P). New York: Biometrics Research, New York State Psychiatric Institute; 2002.
30. McGlashan TH, Miller TJ, Woods SW. Structured Interview for Prodromal Syndromes (SIPS), Version 4.0. New Heaven: Yale University; 2003.
31. Auther AM, Smith CW, Cornblatt BA. Global functioning: Social Scale (GF: Social). Glen Oaks, NY: Zucker-Hillside Hospital; 2006.
32. Niendam TA, Bearden CE, Johnson JK, Cannon TD. Global functioning: Role Scale (GF: Role). Los Angeles, CA: University of California, Los Angeles; 2006.
33. Andreasen NC. The Scale for the Assessment of Positive Symptoms (SAPS). Iowa City: University of Iowa; 1983.
34. Andreasen NC. The Scale for the Assessment of Negative Symptoms (SANS). Iowa City: University of Iowa; 1983.
35. Montgomery SA, Asberg M. A new depression scale designed to be sensitive to change. Br J Psychiatry 1979;134:382-389.
36. Mattila-Evenden M, Svanborg P, Gustavsson P, Åsberg M. Determinants of self-rating and expert rating concordance in psychiatric outpatients, using the affective subscales of the CPRS. Acta Psychiatr Scand 1996; 94:386-396.
37. Fusar-Poli P, Nelson B, Valmaggia L, Yung AR, McGuire PK. Comorbid depressive and anxiety disorders in 509 individuals with an at-risk mental state: impact on psychopathology and transition into psychosis. Schizophr Bull 2014; 40:120-131.