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Volumn 389, Issue 10073, 2017, Pages 1066-1074

Putting polypills into practice: challenges and lessons learned

Author keywords

[No Author keywords available]

Indexed keywords

CARDIOVASCULAR AGENT; ESSENTIAL DRUG;

EID: 85015176282     PISSN: 01406736     EISSN: 1474547X     Source Type: Journal    
DOI: 10.1016/S0140-6736(17)30558-5     Document Type: Review
Times cited : (81)

References (39)
  • 2
    • 84944037667 scopus 로고    scopus 로고
    • Obstacles to developing cost-lowering health technology: the inventor's dilemma
    • 2 Kellermann, AL, Desai, NR, Obstacles to developing cost-lowering health technology: the inventor's dilemma. JAMA 314 (2015), 1447–1448.
    • (2015) JAMA , vol.314 , pp. 1447-1448
    • Kellermann, A.L.1    Desai, N.R.2
  • 3
    • 84982113684 scopus 로고    scopus 로고
    • 2016 European Guidelines on cardiovascular disease prevention in clinical practice: The Sixth Joint Task Force of the European Society of Cardiology and Other Societies on Cardiovascular Disease Prevention in Clinical Practice (constituted by representatives of 10 societies and by invited experts) developed with the special contribution of the European Association for Cardiovascular Prevention & Rehabilitation (EACPR)
    • 3 Piepoli, MF, Hoes, AW, Agewall, S, et al. 2016 European Guidelines on cardiovascular disease prevention in clinical practice: The Sixth Joint Task Force of the European Society of Cardiology and Other Societies on Cardiovascular Disease Prevention in Clinical Practice (constituted by representatives of 10 societies and by invited experts) developed with the special contribution of the European Association for Cardiovascular Prevention & Rehabilitation (EACPR). Eur Heart J 37 (2016), 2315–2381.
    • (2016) Eur Heart J , vol.37 , pp. 2315-2381
    • Piepoli, M.F.1    Hoes, A.W.2    Agewall, S.3
  • 4
    • 85015185851 scopus 로고    scopus 로고
    • HEARTS technical package for cardiovascular disease management in primary health care
    • (accessed Feb 21, 2017).
    • 4 WHO. HEARTS technical package for cardiovascular disease management in primary health care. http://www.who.int/cardiovascular_diseases/hearts/Hearts_package.pdf, 2016 (accessed Feb 21, 2017).
    • (2016)
  • 5
    • 85015162154 scopus 로고    scopus 로고
    • Polypill uses and evidence to date
    • 5 Huffman, MD, Xavier, D, Perel, P, Polypill uses and evidence to date. Lancet 389 (2017), 953–963.
    • (2017) Lancet , vol.389 , pp. 953-963
    • Huffman, M.D.1    Xavier, D.2    Perel, P.3
  • 6
    • 84962050293 scopus 로고    scopus 로고
    • Pragmatic trials for noncommunicable diseases: relieving constraints
    • 6 Patel, A, Webster, R, Pragmatic trials for noncommunicable diseases: relieving constraints. PLoS Med, 13, 2016, e1001986.
    • (2016) PLoS Med , vol.13 , pp. e1001986
    • Patel, A.1    Webster, R.2
  • 7
    • 78650762207 scopus 로고    scopus 로고
    • A Polypill for primary prevention of cardiovascular disease: a feasibility study of the World Health Organization
    • 7 Soliman, E, Mendis, S, Dissanayake, W, et al. A Polypill for primary prevention of cardiovascular disease: a feasibility study of the World Health Organization. Trials, 12, 2011, 3.
    • (2011) Trials , vol.12 , pp. 3
    • Soliman, E.1    Mendis, S.2    Dissanayake, W.3
  • 8
    • 84901723858 scopus 로고    scopus 로고
    • Effect of fixed dose combination treatment on adherence and risk factor control among patients at high risk of cardiovascular disease: randomised controlled trial in primary care
    • 8 Selak, V, Elley, CR, Bullen, C, et al. Effect of fixed dose combination treatment on adherence and risk factor control among patients at high risk of cardiovascular disease: randomised controlled trial in primary care. BMJ, 348, 2014, g3318.
    • (2014) BMJ , vol.348 , pp. g3318
    • Selak, V.1    Elley, C.R.2    Bullen, C.3
  • 9
    • 84883392138 scopus 로고    scopus 로고
    • Effects of a fixed-dose combination strategy on adherence and risk factors in patients with or at high risk of CVD: the UMPIRE randomized clinical trial
    • 9 Thom, S, Poulter, N, Field, J, et al. Effects of a fixed-dose combination strategy on adherence and risk factors in patients with or at high risk of CVD: the UMPIRE randomized clinical trial. JAMA 310 (2013), 918–929.
    • (2013) JAMA , vol.310 , pp. 918-929
    • Thom, S.1    Poulter, N.2    Field, J.3
  • 10
    • 84929903254 scopus 로고    scopus 로고
    • Patients' and providers' perspectives of a polypill strategy to improve cardiovascular prevention in Australian primary health care: a qualitative study set within a pragmatic randomized, controlled trial
    • 10 Liu, H, Massi, L, Laba, TL, et al. Patients' and providers' perspectives of a polypill strategy to improve cardiovascular prevention in Australian primary health care: a qualitative study set within a pragmatic randomized, controlled trial. Circ Cardiovasc Qual Outcomes 8 (2015), 301–308.
    • (2015) Circ Cardiovasc Qual Outcomes , vol.8 , pp. 301-308
    • Liu, H.1    Massi, L.2    Laba, T.L.3
  • 11
    • 84928230401 scopus 로고    scopus 로고
    • Patient preferences for a polypill for the prevention of cardiovascular diseases
    • 11 Laba, TL, Howard, K, Rose, J, et al. Patient preferences for a polypill for the prevention of cardiovascular diseases. Ann Pharmacother 49 (2015), 528–539.
    • (2015) Ann Pharmacother , vol.49 , pp. 528-539
    • Laba, T.L.1    Howard, K.2    Rose, J.3
  • 12
    • 78650529764 scopus 로고    scopus 로고
    • Acceptance of a Polypill approach to prevent cardiovascular disease among a sample of U.S. physicians
    • 12 Viera, AJ, Sheridan, SL, Edwards, T, Soliman, EZ, Harris, R, Furberg, CD, Acceptance of a Polypill approach to prevent cardiovascular disease among a sample of U.S. physicians. Prev Med 52 (2011), 10–15.
    • (2011) Prev Med , vol.52 , pp. 10-15
    • Viera, A.J.1    Sheridan, S.L.2    Edwards, T.3    Soliman, E.Z.4    Harris, R.5    Furberg, C.D.6
  • 13
    • 84874622362 scopus 로고    scopus 로고
    • Could the polypill improve adherence? The patient perspective
    • 13 Bryant, L, Martini, N, Chan, J, et al. Could the polypill improve adherence? The patient perspective. J Prim Health Care 5 (2013), 28–35.
    • (2013) J Prim Health Care , vol.5 , pp. 28-35
    • Bryant, L.1    Martini, N.2    Chan, J.3
  • 14
    • 84971330845 scopus 로고    scopus 로고
    • Stroke survivors', caregivers' and GPs' attitudes towards a polypill for the secondary prevention of stroke: a qualitative interview study
    • 14 Jamison, J, Graffy, J, Mullis, R, Mant, J, Sutton, S, Stroke survivors', caregivers' and GPs' attitudes towards a polypill for the secondary prevention of stroke: a qualitative interview study. BMJ Open, 6, 2016, e010458.
    • (2016) BMJ Open , vol.6 , pp. e010458
    • Jamison, J.1    Graffy, J.2    Mullis, R.3    Mant, J.4    Sutton, S.5
  • 15
    • 84876109223 scopus 로고    scopus 로고
    • Would primary healthcare professionals prescribe a polypill to manage cardiovascular risk? A qualitative interview study
    • 15 Virdee, SK, Greenfield, SM, Fletcher, K, McManus, RJ, Hobbs, FD, Mant, J, Would primary healthcare professionals prescribe a polypill to manage cardiovascular risk? A qualitative interview study. BMJ Open, 3, 2013, e002498.
    • (2013) BMJ Open , vol.3 , pp. e002498
    • Virdee, S.K.1    Greenfield, S.M.2    Fletcher, K.3    McManus, R.J.4    Hobbs, F.D.5    Mant, J.6
  • 16
    • 84937692966 scopus 로고    scopus 로고
    • Patients' views about taking a polypill to manage cardiovascular risk: a qualitative study in primary care
    • 16 Virdee, SK, Greenfield, SM, Fletcher, K, McManus, RJ, Mant, J, Patients' views about taking a polypill to manage cardiovascular risk: a qualitative study in primary care. Br J Gen Pract 65 (2015), e447–e453.
    • (2015) Br J Gen Pract , vol.65 , pp. e447-e453
    • Virdee, S.K.1    Greenfield, S.M.2    Fletcher, K.3    McManus, R.J.4    Mant, J.5
  • 17
    • 84970937465 scopus 로고    scopus 로고
    • Process evaluation of the impact and acceptability of a polypill for prevention of cardiovascular disease
    • 17 Wood, F, Salam, A, Singh, K, et al. Process evaluation of the impact and acceptability of a polypill for prevention of cardiovascular disease. BMJ Open, 5, 2015, e008018.
    • (2015) BMJ Open , vol.5 , pp. e008018
    • Wood, F.1    Salam, A.2    Singh, K.3
  • 18
    • 84945972329 scopus 로고    scopus 로고
    • The effect of a cardiovascular polypill strategy on pill burden
    • 18 Truelove, M, Patel, A, Bompoint, S, et al. The effect of a cardiovascular polypill strategy on pill burden. Cardiovasc Ther 33 (2015), 347–352.
    • (2015) Cardiovasc Ther , vol.33 , pp. 347-352
    • Truelove, M.1    Patel, A.2    Bompoint, S.3
  • 19
    • 84930590680 scopus 로고    scopus 로고
    • A pragmatic randomized trial of a polypill-based strategy to improve use of indicated preventive treatments in people at high cardiovascular disease risk
    • 19 Patel, A, Cass, A, Peiris, D, et al., for the Kanyini Guidelines Adherence with the Polypill (Kanyini GAP) Collaboration. A pragmatic randomized trial of a polypill-based strategy to improve use of indicated preventive treatments in people at high cardiovascular disease risk. Eur J Prev Cardiol 22 (2015), 920–930.
    • (2015) Eur J Prev Cardiol , vol.22 , pp. 920-930
    • Patel, A.1    Cass, A.2    Peiris, D.3
  • 20
    • 84888003452 scopus 로고    scopus 로고
    • Prospective meta-analysis of trials comparing fixed dose combination based care with usual care in individuals at high cardiovascular risk: the SPACE Collaboration
    • 20 Webster, R, Patel, A, Billot, L, et al., SPACE Collaboration. Prospective meta-analysis of trials comparing fixed dose combination based care with usual care in individuals at high cardiovascular risk: the SPACE Collaboration. Int J Cardiol 170 (2013), 30–35.
    • (2013) Int J Cardiol , vol.170 , pp. 30-35
    • Webster, R.1    Patel, A.2    Billot, L.3
  • 21
    • 84955451028 scopus 로고    scopus 로고
    • Effectiveness of fixed dose combination medication (‘polypills’) compared with usual care in patients with cardiovascular disease or at high risk: a prospective, individual patient data meta-analysis of 3140 patients in six countries
    • 21 Webster, R, Patel, A, Selak, V, et al. Effectiveness of fixed dose combination medication (‘polypills’) compared with usual care in patients with cardiovascular disease or at high risk: a prospective, individual patient data meta-analysis of 3140 patients in six countries. Int J Cardiol 205 (2016), 147–156.
    • (2016) Int J Cardiol , vol.205 , pp. 147-156
    • Webster, R.1    Patel, A.2    Selak, V.3
  • 22
    • 84922645435 scopus 로고    scopus 로고
    • A polypill strategy to improve adherence: results from FOCUS (Fixed-dose Combination Drug for Secondary Cardiovascular Prevention) Project
    • 22 Castellano, JM, Sanz, G, Penalvo, JL, et al. A polypill strategy to improve adherence: results from FOCUS (Fixed-dose Combination Drug for Secondary Cardiovascular Prevention) Project. J Am Coll Cardiol 64 (2014), 2071–2082.
    • (2014) J Am Coll Cardiol , vol.64 , pp. 2071-2082
    • Castellano, J.M.1    Sanz, G.2    Penalvo, J.L.3
  • 23
    • 84981516856 scopus 로고    scopus 로고
    • Do polypills lead to neglect of lifestyle risk factors? Findings from an individual participant data meta-analysis among 3140 patients at high risk of cardiovascular disease
    • 23 Selak, V, Bullen, C, Stepien, S, et al. Do polypills lead to neglect of lifestyle risk factors? Findings from an individual participant data meta-analysis among 3140 patients at high risk of cardiovascular disease. Eur J Prev Cardiol 23 (2016), 1393–1400.
    • (2016) Eur J Prev Cardiol , vol.23 , pp. 1393-1400
    • Selak, V.1    Bullen, C.2    Stepien, S.3
  • 24
    • 84964914194 scopus 로고    scopus 로고
    • The Fuster-CNIC-Ferrer cardiovascular polypill: a polypill for secondary cardiovascular prevention
    • 24 Tamargo, J, Castellano, JM, Fuster, V, The Fuster-CNIC-Ferrer cardiovascular polypill: a polypill for secondary cardiovascular prevention. Int J Cardiol 201 (2015), S15–S22.
    • (2015) Int J Cardiol , vol.201 , pp. S15-S22
    • Tamargo, J.1    Castellano, J.M.2    Fuster, V.3
  • 25
    • 79957456895 scopus 로고    scopus 로고
    • An international randomised placebo-controlled trial of a four-component combination pill (“polypill”) in people with raised cardiovascular risk
    • 25 PILL Collaborative Group, Rodgers, A, Patel, A, et al. An international randomised placebo-controlled trial of a four-component combination pill (“polypill”) in people with raised cardiovascular risk. PLoS One, 6, 2011, e19857.
    • (2011) PLoS One , vol.6 , pp. e19857
    • Rodgers, A.1    Patel, A.2
  • 26
    • 84945260743 scopus 로고    scopus 로고
    • Polypill: progress and challenges to global use—update on the trials and policy implementation
    • 26 Webster, R, Rodgers, A, Polypill: progress and challenges to global use—update on the trials and policy implementation. Curr Cardiol Rep 17 (2015), 1–8.
    • (2015) Curr Cardiol Rep , vol.17 , pp. 1-8
    • Webster, R.1    Rodgers, A.2
  • 27
    • 80053563341 scopus 로고    scopus 로고
    • Use of secondary prevention drugs for cardiovascular disease in the community in high-income, middle-income, and low-income countries (the PURE Study): a prospective epidemiological survey
    • 27 Yusuf, S, Islam, S, Chow, CK, et al. Use of secondary prevention drugs for cardiovascular disease in the community in high-income, middle-income, and low-income countries (the PURE Study): a prospective epidemiological survey. Lancet 378 (2011), 1231–1243.
    • (2011) Lancet , vol.378 , pp. 1231-1243
    • Yusuf, S.1    Islam, S.2    Chow, C.K.3
  • 31
    • 33746578047 scopus 로고    scopus 로고
    • The WHO public-health approach to antiretroviral treatment against HIV in resource-limited settings
    • 31 Gilks, CF, Crowley, S, Ekpini, R, et al. The WHO public-health approach to antiretroviral treatment against HIV in resource-limited settings. Lancet 368 (2006), 505–510.
    • (2006) Lancet , vol.368 , pp. 505-510
    • Gilks, C.F.1    Crowley, S.2    Ekpini, R.3
  • 32
    • 33747361000 scopus 로고    scopus 로고
    • Cardiovascular disease prevention with a multidrug regimen in the developing world: a cost-effectiveness analysis
    • 32 Gaziano, TA, Opie, LH, Weinstein, MC, Cardiovascular disease prevention with a multidrug regimen in the developing world: a cost-effectiveness analysis. Lancet 368 (2006), 679–686.
    • (2006) Lancet , vol.368 , pp. 679-686
    • Gaziano, T.A.1    Opie, L.H.2    Weinstein, M.C.3
  • 33
    • 84903159932 scopus 로고    scopus 로고
    • 2013 ACC/AHA guideline on the assessment of cardiovascular risk: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines
    • 33 Goff, DC Jr, Lloyd-Jones, DM, Bennett, G, et al. 2013 ACC/AHA guideline on the assessment of cardiovascular risk: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. Circulation 129:suppl 2 (2014), S49–S73.
    • (2014) Circulation , vol.129 , pp. S49-S73
    • Goff, D.C.1    Lloyd-Jones, D.M.2    Bennett, G.3
  • 35
    • 47149088261 scopus 로고    scopus 로고
    • Predicting cardiovascular risk in England and Wales: prospective derivation and validation of QRISK2
    • 35 Hippisley-Cox, J, Coupland, C, Vinogradova, Y, et al. Predicting cardiovascular risk in England and Wales: prospective derivation and validation of QRISK2. BMJ 336 (2008), 1475–1482.
    • (2008) BMJ , vol.336 , pp. 1475-1482
    • Hippisley-Cox, J.1    Coupland, C.2    Vinogradova, Y.3
  • 38
    • 85015209956 scopus 로고    scopus 로고
    • Essential medicines and health products: prequalification of medicines. Guidance documents
    • (accessed Feb 21, 2017).
    • 38 WHO. Essential medicines and health products: prequalification of medicines. Guidance documents. https://extranet.who.int/prequal/content/WHOguidance-documents, 2017 (accessed Feb 21, 2017).
    • (2017)
  • 39
    • 85016924858 scopus 로고    scopus 로고
    • A step ahead in secondary prevention of cardiovascular risk. consensus document on clinical use of the polypill
    • 39 González-Juanatey, JR, Mostaza, JM, Lobos, JM, Abarca, B, Llisterri, JL, A step ahead in secondary prevention of cardiovascular risk. consensus document on clinical use of the polypill. Rev Esp Cardiol (Engl ed) 69 (2016), 547–550.
    • (2016) Rev Esp Cardiol (Engl ed) , vol.69 , pp. 547-550
    • González-Juanatey, J.R.1    Mostaza, J.M.2    Lobos, J.M.3    Abarca, B.4    Llisterri, J.L.5


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