Association of radiologic indicators of frailty with 1-year mortality in older trauma patients: Opportunistic screening for sarcopenia and osteopenia

JAMA Surgery

Volumn 152, Issue 2, 2017, Pages

  Kaplan, Stephen J ^a,b   Pham, Tam N ^c   Arbabi, Saman ^c   Gross, Joel A ^b   Damodarasamy, Mamatha ^b   Bentov, Itay ^c   Taitsman, Lisa A ^b   Mitchell, Steven H ^c   Reed, May J ^b  

^a VIRGINIA MASON MEDICAL CENTER   (United States)

^b UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF WASHINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AGED; ARTICLE; COHORT ANALYSIS; DISEASE ASSOCIATION; FEMALE; FRAILTY; HOSPITAL COST; HOSPITAL DISCHARGE; HOSPITAL MORTALITY; HOSPITAL READMISSION; HUMAN; INJURY; LENGTH OF STAY; MAJOR CLINICAL STUDY; MALE; MORTALITY RISK; OSTEOPENIA; OUTCOME ASSESSMENT; PRIORITY JOURNAL; RETROSPECTIVE STUDY; SARCOPENIA; SCREENING TEST; VERY ELDERLY; X-RAY COMPUTED TOMOGRAPHY; ABDOMEN; BONE DISEASES, METABOLIC; CASE CONTROL STUDY; CAUSE OF DEATH; DIAGNOSTIC IMAGING; ECONOMICS; FRAIL ELDERLY; HEALTH STATUS INDICATOR; PELVIS; STATISTICS AND NUMERICAL DATA; TIME FACTOR; WASHINGTON;

ABDOMEN; AGED; AGED, 80 AND OVER; BONE DISEASES, METABOLIC; CASE-CONTROL STUDIES; CAUSE OF DEATH; FEMALE; FRAIL ELDERLY; HEALTH STATUS INDICATORS; HOSPITAL COSTS; HUMANS; LENGTH OF STAY; MALE; PATIENT DISCHARGE; PATIENT READMISSION; PELVIS; RETROSPECTIVE STUDIES; SARCOPENIA; TIME FACTORS; TOMOGRAPHY, X-RAY COMPUTED; WASHINGTON; WOUNDS AND INJURIES;

EID: 85014780757     PISSN: 21686254     EISSN: None     Source Type: Journal    
DOI: 10.1001/jamasurg.2016.4604     Document Type: Article

References (38)

1. National Trauma Data Bank (NTDB). NTDB 2015 annual report. https://www.facs.org/quality-programs/trauma/ntdb/docpub. Accessed February 24, 2016.
2. Fawcett VJ, Flynn-O'Brien KT, Shorter Z, et al. Risk factors for unplanned readmissions in older adult trauma patients in Washington State: a competing risk analysis. J AmColl Surg. 2015;220 (3):330-338.
3. DeLa'O CM, Kashuk J, Rodriguez A, Zipf J, Dumire RD. The Geriatric Trauma Institute: reducing the increasing burden of senior trauma care. Am J Surg. 2014;208(6):988-994.
4. Min L, Cryer H, Chan C-L, Roth C, Tillou A. Quality of care delivered before vs after a quality-improvement intervention for acute geriatric trauma. J AmColl Surg. 2015;220(5): 820-830.
5. Mackersie RC; Care of the Underserved. For the care of the underserved. J Trauma Acute Care Surg. 2014;77(5):653-659.
6. Morley JE, Vellas B, van Kan GA, et al. Frailty consensus: a call to action. J AmMed Dir Assoc. 2013;14(6):392-397.
7. Joseph B, Pandit V, Zangbar B, et al. Superiority of frailty over age in predicting outcomes among geriatric trauma patients: a prospective analysis. JAMA Surg. 2014;149(8):766-772.
8. Maxwell CA, Mion LC, Mukherjee K, et al. Feasibility of screening for preinjury frailty in hospitalized injured older adults. J Trauma Acute Care Surg. 2015;78(4):844-851.
9. Joseph B, Pandit V, Zangbar B, et al. Validating trauma-specific frailty index for geriatric trauma patients: a prospective analysis. J AmColl Surg. 2014;219(1):10-17.e1.
10. Bauer JM, Sieber CC. Sarcopenia and frailty: a clinician's controversial point of view. Exp Gerontol. 2008;43(7):674-678.
11. Landi F, Calvani R, Cesari M, et al. Sarcopenia as the biological substrate of physical frailty. Clin Geriatr Med. 2015;31(3):367-374.
12. Cesari M, Landi F, Vellas B, Bernabei R, Marzetti E. Sarcopenia and physical frailty: two sides of the same coin. Front Aging Neurosci. 2014;6:192.
13. Cooper C, Dere W, Evans W, et al. Frailty and sarcopenia: definitions and outcome parameters. Osteoporos Int. 2012;23(7):1839-1848.
14. Morley JE, von Haehling S, Anker SD, Vellas B. From sarcopenia to frailty: a road less traveled. J Cachexia Sarcopenia Muscle. 2014;5(1):5-8.
15. Cruz-Jentoft AJ, Baeyens JP, Bauer JM, et al; European Working Group on Sarcopenia in Older People. Sarcopenia: European consensus on definition and diagnosis: report of the European Working Group on Sarcopenia in Older People. Age Ageing. 2010;39(4):412-423.
16. Levolger S, van Vugt JL, de Bruin RW, Ijzermans JN. Systematic review of sarcopenia in patients operated on for gastrointestinal and hepatopancreatobiliary malignancies. Br J Surg. 2015;102(12):1448-1458.
17. Landi F, Cruz-Jentoft AJ, Liperoti R, et al. Sarcopenia and mortality risk in frail older persons aged 80 years and older: results from il SIRENTE study. Age Ageing. 2013;42(2):203-209.
18. Moisey LL, Mourtzakis M, Cotton BA, et al; Nutrition and Rehabilitation Investigators Consortium (NUTRIC). Skeletal muscle predicts ventilator-free days, ICU-free days, and mortality in elderly ICU patients. Crit Care. 2013;17(5):R206.
19. Fairchild B, Webb TP, Xiang Q, Tarima S, Brasel KJ. Sarcopenia and frailty in elderly trauma patients. World J Surg. 2015;39(2):373-379.
20. Mueller N, Murthy S, Tainter CR, et al. Can sarcopenia quantified by ultrasound of the rectus femoris muscle predict adverse outcome of surgical intensive care unit patients as well as frailty? a prospective, observational cohort study. Ann Surg. 2015;264(6):1116-1124.
21. Fried LP, Ferrucci L, Darer J, Williamson JD, Anderson G. Untangling the concepts of disability, frailty, and comorbidity: implications for improved targeting and care. J Gerontol A Biol Sci Med Sci. 2004;59(3):255-263.
22. Frisoli A Jr, Chaves PH, Ingham SJM, Fried LP. Severe osteopenia and osteoporosis, sarcopenia, and frailty status in community-dwelling older women: results from the Women's Health and Aging Study (WHAS) II. Bone. 2011;48(4):952-957.
23. Topinková E. Aging, disability and frailty. Ann Nutr Metab. 2008;52(suppl 1):6-11.
24. Ensrud KE, Ewing SK, Cawthon PM, et al; Osteoporotic Fractures in Men Research Group. A comparison of frailty indexes for the prediction of falls, disability, fractures, and mortality in older men. J AmGeriatr Soc. 2009;57(3):492-498.
25. Ensrud KE, Ewing SK, Taylor BC, et al. Comparison of 2 frailty indexes for prediction of falls, disability, fractures, and death in older women. Arch Intern Med. 2008;168(4):382-389.
26. de Vries OJ, Peeters GM, Lips P, Deeg DJ. Does frailty predict increased risk of falls and fractures? a prospective population-based study. Osteoporos Int. 2013;24(9):2397-2403.
27. Johnell O, Kanis JA, Oden A, et al. Predictive value of BMD for hip and other fractures. J Bone Miner Res. 2005;20(7):1185-1194.
28. Bliuc D, Alarkawi D, Nguyen TV, Eisman JA, Center JR. Risk of subsequent fractures and mortality in elderly women and men with fragility fractures with and without osteoporotic bone density: the Dubbo Osteoporosis Epidemiology Study. J Bone Miner Res. 2015;30(4):637-646.
29. Pickhardt PJ, Pooler BD, Lauder T, del Rio AM, Bruce RJ, Binkley N. Opportunistic screening for osteoporosis using abdominal computed tomography scans obtained for other indications. Ann Intern Med. 2013;158(8):588-595.
30. Prado CM, Lieffers JR, McCargar LJ, et al. Prevalence and clinical implications of sarcopenic obesity in patients with solid tumours of the respiratory and gastrointestinal tracts: a population-based study. Lancet Oncol. 2008;9(7): 629-635.
31. Boutin RD, Yao L, Canter RJ, Lenchik L. Sarcopenia: current concepts and imaging implications. AJR AmJ Roentgenol. 2015;205(3): W255-W266.
32. Pickhardt PJ, Lee LJ, del Rio AM, et al. Simultaneous screening for osteoporosis at CT colonography: bone mineral density assessment using MDCT attenuation techniques compared with the DXA reference standard. J Bone Miner Res. 2011;26(9):2194-2203.
33. Quan H, Li B, Couris CM, et al. Updating and validating the Charlson comorbidity index and score for risk adjustment in hospital discharge abstracts using data from 6 countries. Am J Epidemiol. 2011; 173(6):676-682.
34. Suzman R, Riley MW. Introducing the "oldest old." Milbank Mem Fund Q Health Soc. 1985;63(2): 177-186.
35. Buta BJ, Walston JD, Godino JG, et al. Frailty assessment instruments: systematic characterization of the uses and contexts of highly-cited instruments. Ageing Res Rev. 2016;26: 53-61.
36. Buettner S, Wagner D, Kim Y, et al. Inclusion of sarcopenia outperforms the modified frailty index in predicting 1-year mortality among 1,326 patients undergoing gastrointestinal surgery for a malignant indication. J AmColl Surg. 2016;222(4):397-407.e2.
37. Collard RM, Boter H, Schoevers RA, Oude Voshaar RC. Prevalence of frailty in community-dwelling older persons: a systematic review. J AmGeriatr Soc. 2012;60(8):1487-1492.
38. McDonald VS, Thompson KA, Lewis PR, Sise CB, Sise MJ, Shackford SR. Frailty in trauma: a systematic review of the surgical literature for clinical assessment tools. J Trauma Acute Care Surg. 2016;80(5):824-834.