Epicardial adipose tissue microbial colonization and inflammasome activation in acute coronary syndrome

International Journal of Cardiology

Volumn 236, Issue , 2017, Pages 95-99

  Pedicino, Daniela ^a   Severino, Anna ^a   Ucci, Sara ^a   Bugli, Francesca ^a   Flego, Davide ^a   Giglio, Ada F ^a   Trotta, Francesco ^a   Ruggio, Aureliano ^a   Lucci, Claudia ^a   Iaconelli, Antonio ^a   Paroni Sterbini, Francesco ^a   Biasucci, Luigi M ^a   Sanguinetti, Maurizio ^a   Glieca, Franco ^b   Luciani, Nicola ^b   Massetti, Massimo ^b   Crea, Filippo ^a   Liuzzo, Giovanna ^a  

^a CATHOLIC UNIVERSITY   (Italy)

^b CATHOLIC UNIVERSITY   (Italy)

Author keywords

Acute coronary syndrome; Atherosclerosis; Epicardial adipose tissue; Inflammasome; Inflammation; Microbiome

Indexed keywords

BACTERIAL DNA; CRYOPYRIN; INFLAMMASOME; INTERLEUKIN 1BETA; MESSENGER RNA;

ACUTE CORONARY SYNDROME; ADULT; AGED; ARTICLE; BACTERIUM IDENTIFICATION; CONTROLLED STUDY; CORONARY ARTERY ATHEROSCLEROSIS; CORONARY ARTERY BYPASS GRAFT; EPICARDIAL FAT; FEMALE; GENE EXPRESSION; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; MICROBIAL COLONIZATION; MICROBIAL COMMUNITY; MITRAL VALVE REGURGITATION; NEXT GENERATION SEQUENCING; NONHUMAN; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPECIES IDENTIFICATION; STABLE ANGINA PECTORIS; ADIPOSE TISSUE; BACTERIAL COUNT; CORONARY BLOOD VESSEL; IMMUNOLOGY; ISOLATION AND PURIFICATION; ITALY; MICROBIOLOGY; MICROFLORA; MIDDLE AGED; PATHOLOGY; PERICARDIUM; PHYSIOLOGY; PROCEDURES; STATISTICS;

ACUTE CORONARY SYNDROME; ADIPOSE TISSUE; AGED; COLONY COUNT, MICROBIAL; CORONARY ARTERY BYPASS; CORONARY VESSELS; DNA, BACTERIAL; FEMALE; HUMANS; INFLAMMASOMES; INTERLEUKIN-1BETA; ITALY; MALE; MICROBIOTA; MIDDLE AGED; NLR FAMILY, PYRIN DOMAIN-CONTAINING 3 PROTEIN; PERICARDIUM; STATISTICS AS TOPIC;

EID: 85014348545     PISSN: 01675273     EISSN: 18741754     Source Type: Journal    
DOI: 10.1016/j.ijcard.2017.02.040     Document Type: Article

References (14)

1. [1] Libby, P., Ridker, P.M., Hansson, G.K., Inflammation in atherosclerosis: from pathophysiology to practice. J. Am. Coll. Cardiol. 54 (2009), 2129–2138.
2. [2] Man, S.M., Kanneganti, T.D., Regulation of inflammasome activation. Immunol. Rev. 265:1 (2015), 6–21.
3. [3] Bando, S., Fukuda, D., Soeki, T., et al. Expression of NLRP3 in subcutaneous adipose tissue is associated with coronary atherosclerosis. Atherosclerosis 242:2 (2015), 407–414.
4. [4] Afrasyab, A., Qu, P., Zhao, Y., et al. Correlation of NLRP3 with severity and prognosis of coronary atherosclerosis in acute coronary syndrome patients. Heart Vessel. 31:8 (2016), 1218–1229.
5. [5] Pedicino, D., Giglio, A.F., Galiffa, V.A., et al. Infections, immunity and atherosclerosis: pathogenic mechanisms and unsolved questions. Int. J. Cardiol. 166:3 (2013), 572–583.
6. [6] Liuzzo, G., Ciervo, A., Niccoli, G., et al. Chlamydia pneumoniae in coronary atherosclerotic plaques and coronary instability. Int. J. Cardiol. 147:1 (2011), 176–178.
7. [7] Niccoli, G., Severino, A., Pieroni, M., et al. Parvovirus B19 at the culprit coronary stenosis predicts outcome after stenting. Eur. J. Clin. Investig. 44:2 (2014), 208–218.
8. [8] Mazurek, T., Zhang, L., Zalewski, A., et al. Human epicardial adipose tissue is a source of inflammatory mediators. Circulation 108:20 (2003), 2460–2466.
9. [9] Coats, A.J.S., Shewan, L.G., Statement on authorship and publishing ethics in the International Journal of Cardiology. Int. J. Cardiol. 153 (2011), 239–240.
10. [10] Crea, F., Liuzzo, G., Pathogenesis of acute coronary syndromes. J. Am. Coll. Cardiol. 61:1 (2013), 1–11.
11. [11] Serra e Silva Filho, W., Casarin, R.C., Nicolela, E.L. Jr., Passos, H.M., Sallum, A.W., Gonçalves, R.B., Microbial diversity similarities in periodontal pockets and atheromatous plaques of cardiovascular disease patients. PLoS One, 9(10), Oct 16 2014, e109761.
12. [12] Pedicino, D., Severino, A., Ucci, S., et al. Epicardial adipose tissue microbial colonization and inflammasome activation in acute coronary syndrome. Int. J. Cardiol. 236 (2017), 95–99.
13. [13] Altschul, S.F., Madden, T.L., Schaffer, A.A., et al. Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. Nucleic Acids Res. 25 (1997), 3389–3402.
14. [14] Curran, S.A., Hollan, I., Erridge, C., et al. Bacteria in the adventitia of cardiovascular disease patients with and without rheumatoid arthritis. PLoS One, 9(5), 2014, e98627.