Correcting for cell-type heterogeneity in epigenome-wide association studies: Revisiting previous analyses

Nature Methods

Volumn 14, Issue 3, 2017, Pages 216-217

  Zheng, Shijie C ^a   Beck, Stephan ^b   Jaffe, Andrew E ^c,d   Koestler, Devin C ^e   Hansen, Kasper D ^c,f   Houseman, Andres E ^g   Irizarry, Rafael A ^h,i   Teschendorff, Andrew E ^a,b,j  

^a INSTITUTE OF GEOLOGY AND GEOPHYSICS   (China)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

^d Johns Hopkins University   (United States)

^e UNIVERSITY OF KANSAS SCHOOL OF MEDICINE   (United States)

^f JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^g OREGON STATE UNIVERSITY   (United States)

^h DANA FARBER CANCER INSTITUTE   (United States)

ⁱ HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^j UNIVERSITY COLLEGE LONDON   (United Kingdom)

more..

Author keywords

[No Author keywords available]

Indexed keywords

DNA;

BREAST CANCER; BREAST CANCER CELL LINE; BREAST TISSUE; CELLS BY BODY ANATOMY; DNA METHYLATION; HUMAN; LETTER; PRIORITY JOURNAL; CPG ISLAND; GENOME-WIDE ASSOCIATION STUDY;

CPG ISLANDS; GENOME-WIDE ASSOCIATION STUDY; HUMANS;

EID: 85014341578     PISSN: 15487091     EISSN: 15487105     Source Type: Journal    
DOI: 10.1038/nmeth.4187     Document Type: Letter

References (9)

1. Jaffe, A.E. & Irizarry, R.A. Genome Biol. 15, R31 (2014).
2. Houseman, E.A. et al. BMC Bioinformatics 13, 86 (2012).
3. Houseman, E.A., Molitor, J. & Marsit, C.J. Bioinformatics 30, 1431-1439 (2014).
4. Leek, J.T. & Storey, J.D. PLoS Genet. 3, e161 (2007).
5. Zou, J., Lippert, C., Heckerman, D., Aryee, M. & Listgarten, J. Nat. Methods 11, 309-311 (2014).
6. Gagnon-Bartsch, J.A. & Speed, T.P. Biostatistics 13, 539-552 (2012).
7. Teschendorff, A.E., Zhuang, J. & Widschwendter, M. Bioinformatics 27, 1496-1505 (2011).
8. Rahmani, E. et al. Nat. Methods 13, 443-445 (2016).
9. Liu, Y. et al. Nat. Biotechnol. 31, 142-147 (2013).