PSA Detection with Femtomolar Sensitivity and a Broad Dynamic Range Using SERS Nanoprobes and an Area-Scanning Method

ACS Sensors

Volumn 1, Issue 6, 2016, Pages 645-649

  Chang, Hyejin ^a   Kang, Homan ^a,d   Ko, Eunbyeol ^a   Jun, Bong Hyun ^b   Lee, Ho Young ^c   Lee, Yoon Sik ^a   Jeong, Dae Hong ^a  

^a Seoul National University   (South Korea)

^b Konkuk University   (South Korea)

^c Seoul National University Bundang Hospital   (South Korea)

^d MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

area scanning; immunoassay; prostate specific antigen (PSA); SERS nanoprobe; surface enhanced Raman scattering (SERS)

Indexed keywords

ANTIGENS; NANOPROBES; RAMAN SCATTERING; RELIABILITY ANALYSIS; SCANNING; SENSITIVITY ANALYSIS; UROLOGY;

IMMUNOASSAY; LIMITED DYNAMIC RANGES; PARTICLE VARIATIONS; PROSTATE SPECIFIC ANTIGEN; RELIABILITY AND SENSITIVITY; SINGLE PARTICLE DETECTION; SURFACE ENHANCED RAMAN SCATTERING (SERS); WIDE DYNAMIC RANGE;

SURFACE SCATTERING;

EID: 85014322160     PISSN: None     EISSN: 23793694     Source Type: Journal    
DOI: 10.1021/acssensors.6b00053     Document Type: Article

References (26)

1. Henry, N. L.; Hayes, D. F. Cancer biomarkers Mol. Oncol. 2012, 6, 140-146 10.1016/j.molonc.2012.01.010
2. Ray, S.; Reddy, P. J.; Jain, R.; Gollapalli, K.; Moiyadi, A.; Srivastava, S. Proteomic technologies for the identification of disease biomarkers in serum: advances and challenges ahead Proteomics 2011, 11, 2139-2161 10.1002/pmic.201000460
3. Cretich, M.; Monroe, M. R.; Reddington, A.; Zhang, X.; Daaboul, G. G.; Damin, F.; Sola, L.; Unlu, M. S.; Chiari, M. Interferometric silicon biochips for label and label-free DNA and protein microarrays Proteomics 2012, 12, 2963-2977 10.1002/pmic.201200202
4. Lang, Q.; Wang, F.; Yin, L.; Liu, M.; Petrenko, V. A.; Liu, A. Specific probe selection from landscape phage display library and its application in enzyme-linked immunosorbent assay of free prostate-specific antigen Anal. Chem. 2014, 86, 2767-2774 10.1021/ac404189k
5. Gu, B.; Xu, C.; Yang, C.; Liu, S.; Wang, M. ZnO quantum dot labeled immunosensor for carbohydrate antigen 19-9 Biosens. Bioelectron. 2011, 26, 2720-2723 10.1016/j.bios.2010.09.031
6. Gao, Z.; Hou, L.; Xu, M.; Tang, D. Enhanced colorimetric immunoassay accompanying with enzyme cascade amplification strategy for ultrasensitive detection of low-abundance protein Sci. Rep. 2014, 4, 3966 10.1038/srep03966
7. Wu, L.; Wang, Z.; Zong, S.; Huang, Z.; Zhang, P.; Cui, Y. A SERS-based immunoassay with highly increased sensitivity using gold/silver core-shell nanorods Biosens. Bioelectron. 2012, 38, 94-99 10.1016/j.bios.2012.05.005
8. Rusling, J. F. Multiplexed electrochemical protein detection and translation to personalized cancer diagnostics Anal. Chem. 2013, 85, 5304-5310 10.1021/ac401058v
9. Alvarez-Puebla, R. A.; Liz-Marzan, L. M. SERS-based diagnosis and biodetection Small 2010, 6, 604-610 10.1002/smll.200901820
10. Narayanan, R.; Lipert, R. J.; Porter, M. D. Cetyltrimethylammonium bromide-modified spherical and cube-like gold nanoparticles as extrinsic Raman labels in surface-enhanced Raman spectroscopy based heterogeneous immunoassays Anal. Chem. 2008, 80, 2265-2271 10.1021/ac7026436
11. Lee, H. E.; Lee, H. K.; Chang, H.; Ahn, H. Y.; Erdene, N.; Lee, H. Y.; Lee, Y.-S.; Jeong, D. H.; Chung, J.; Nam, K. T. Virus templated gold nanocube chain for SERS nanoprobe Small 2014, 10, 3007-3011 10.1002/smll.201400527
12. Granger, J. H.; Granger, M. C.; Firpo, M. A.; Mulvihill, S. J.; Porter, M. D. Toward development of a surface-enhanced Raman scattering (SERS)-based cancer diagnostic immunoassay panel Analyst 2013, 138, 410-416 10.1039/C2AN36128K
13. Guarrotxena, N.; Bazan, G. C. Antitags: SERS-encoded nanoparticle assemblies that enable single-spot multiplex protein detection Adv. Mater. 2014, 26, 1941-1946 10.1002/adma.201304107
14. Wang, Y.; Salehi, M.; Schutz, M.; Schlücker, S. Femtogram detection of cytokines in a direct dot-blot assay using SERS microspectroscopy and hydrophilically stabilized Au-Ag nanoshells Chem. Commun. 2014, 50, 2711-2714 10.1039/c3cc48633h
15. Lee, M.; Lee, S.; Lee, J. H.; Lim, H. W.; Seong, G. H.; Lee, E. K.; Chang, S. I.; Oh, C. H.; Choo, J. Highly reproducible immunoassay of cancer markers on a gold-patterned microarray chip using surface-enhanced Raman scattering imaging Biosens. Bioelectron. 2011, 26, 2135-2141 10.1016/j.bios.2010.09.021
16. Wang, G.; Lipert, R. J.; Jain, M.; Kaur, S.; Chakraboty, S.; Torres, M. P.; Batra, S. K.; Brand, R. E.; Porter, M. D. Detection of the potential pancreatic cancer marker MUC4 in serum using surface-enhanced Raman scattering Anal. Chem. 2011, 83, 2554-2561 10.1021/ac102829b
17. Chang, H.; Kang, H.; Jeong, S.; Ko, E.; Lee, Y.-S.; Lee, H.-Y.; Jeong, D. H. A fast and reliable readout method for quantitative analysis of surface-enhanced Raman scattering nanoprobes on chip surface Rev. Sci. Instrum. 2015, 86, 055004 10.1063/1.4921100
18. Thaxton, C. S.; Elghanian, R.; Thomas, A. D.; Stoeva, S. I.; Lee, J. S.; Smith, N. D.; Schaeffer, A. J.; Klocker, H.; Horninger, W.; Bartsch, G.; Mirkin, C. A. Nanoparticle-based bio-barcode assay redefines ″undetectable″ PSA and biochemical recurrence after radical prostatectomy Proc. Natl. Acad. Sci. U. S. A. 2009, 106, 18437-18442 10.1073/pnas.0904719106
19. De Angelis, G.; Rittenhouse, H. G.; Mikolajczyk, S. D.; Blair Shamel, L.; Semjonow, A. Twenty Years of PSA: From Prostate Antigen to Tumor Marker Rev. Urol. 2007, 9, 113-123
20. Kim, J. H.; Kim, J. S.; Choi, H.; Lee, S. M.; Jun, B. H.; Yu, K. N.; Kuk, E.; Kim, Y. K.; Jeong, D. H.; Cho, M. H.; Lee, Y.-S. Nanoparticle probes with surface enhanced Raman spectroscopic tags for cellular cancer targeting Anal. Chem. 2006, 78, 6967-6973 10.1021/ac0607663
21. Kim, J. H.; Kang, H.; Kim, S.; Jun, B. H.; Kang, T.; Chae, J.; Jeong, S.; Kim, J.; Jeong, D. H.; Lee, Y.-S. Encoding peptide sequences with surface-enhanced Raman spectroscopic nanoparticles Chem. Commun. 2011, 47, 2306-2308 10.1039/C0CC04415F
22. Pieczonka, N. P.; Aroca, R. F. Single molecule analysis by surfaced-enhanced Raman scattering Chem. Soc. Rev. 2008, 37, 946-954 10.1039/b709739p
23. Kang, H.; Jeong, S.; Park, Y.; Yim, J.; Jun, B.-H.; Kyeong, S.; Yang, J.-K.; Kim, G.; Hong, S.; Lee, L. P.; Kim, J.-H.; Lee, H.-Y.; Jeong, D. H.; Lee, Y.-S. Near-Infrared SERS Nanoprobes with Plasmonic Au/Ag Hollow-Shell Assemblies for In Vivo Multiplex Detection Adv. Funct. Mater. 2013, 23, 3719-3727 10.1002/adfm.201203726
24. Jalani, G.; Lee, S.; Jung, C. W.; Jang, H.; Choo, J.; Lim, D. W. Controlled biohybrid nanoprobes with silver nanoparticle clusters for Raman imaging Analyst 2013, 138, 4756-4759 10.1039/c3an00943b
25. Huang, P.-J.; Chau, L.-K.; Yang, T.-S.; Tay, L.-L.; Lin, T.-T. Nanoaggregate-Embedded Beads as Novel Raman Labels for Biodetection Adv. Funct. Mater. 2009, 19, 242-248 10.1002/adfm.200800961
26. Chen, G.; Wang, Y.; Yang, M.; Xu, J.; Goh, S. J.; Pan, M.; Chen, H. Measuring ensemble-averaged surface-enhanced Raman scattering in the hotspots of colloidal nanoparticle dimers and trimers J. Am. Chem. Soc. 2010, 132, 3644-3645 10.1021/ja9090885