Optimal strategies for controlling particle size in antisolvent crystallization operations

IFAC Proceedings Volumes (IFAC-PapersOnline)

Volumn 40, Issue 5, 2007, Pages 177-182

  Nowee, S M ^a   Abbas, A ^b   Romagnoli, J A ^c   Yeo, P ^d  

^a UNIVERSITY OF SYDNEY   (Australia)

^b The University of New South Wales Singapore   (Singapore)

^c LOUISIANA STATE UNIVERSITY   (United States)

^d Nanyang Technological University   (Singapore)

Author keywords

Antisolvent crystallization; Crystal size distribution; FBRM; Feed profile; Growth; Nucleation; Optimization; Parameter estimation; Particle size; Pharmaceutical

Indexed keywords

CRYSTALLIZATION KINETICS; DRUG PRODUCTS; GROWTH (MATERIALS); NUCLEATION; OPTIMAL SYSTEMS; OPTIMIZATION; PARAMETER ESTIMATION;

ANTI-SOLVENT CRYSTALLIZATION; CRYSTAL SIZE DISTRIBUTIONS; DYNAMIC OPTIMIZATION; EXPERIMENTAL VALIDATIONS; FBRM; FEED PROFILES; OPTIMAL STRATEGIES; POPULATION BALANCES;

PARTICLE SIZE;

EID: 85014185209     PISSN: 14746670     EISSN: None     Source Type: Conference Proceeding    
DOI: 10.3182/20070606-3-MX-2915.00077     Document Type: Conference Paper

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