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Volumn 61, Issue 3, 2017, Pages

In vitro activity of gepotidacin (GSK2140944) against Neisseria gonorrhoeae

Author keywords

Minimum bactericidal activity; Neisseria gonorrhoeae; Postantibiotic effect

Indexed keywords

AZITHROMYCIN; CEFTRIAXONE; CIPROFLOXACIN; GEPOTIDACIN; MOXIFLOXACIN; TETRACYCLINE; ACENAPHTHENE DERIVATIVE; ANTIINFECTIVE AGENT; DNA TOPOISOMERASE INHIBITOR; DNA TOPOISOMERASE IV; FUSED HETEROCYCLIC RINGS;

EID: 85014122938     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.02047-16     Document Type: Article
Times cited : (53)

References (24)
  • 1
    • 0003449320 scopus 로고    scopus 로고
    • Centers for Disease Control and Prevention. Centers for Disease Control and Prevention, Atlanta, GA
    • Centers for Disease Control and Prevention. 2014. 2013 sexually transmitted disease surveillance. Centers for Disease Control and Prevention, Atlanta, GA.
    • (2014) 2013 Sexually Transmitted Disease Surveillance
  • 2
    • 0033017798 scopus 로고    scopus 로고
    • From epidemiological synergy to public health policy and practice: The contribution of other sexually transmitted diseases to sexual transmission of HIV infection
    • Fleming DT, Wasserheit JN. 1999. From epidemiological synergy to public health policy and practice: the contribution of other sexually transmitted diseases to sexual transmission of HIV infection. Sex Transm Infect 75:3-17. https://doi.org/10.1136/sti.75.1.3.
    • (1999) Sex Transm Infect , vol.75 , pp. 3-17
    • Fleming, D.T.1    Wasserheit, J.N.2
  • 3
    • 34247145113 scopus 로고    scopus 로고
    • Update to CDC's sexually transmitted diseases treatment guidelines, 2006: Fluoroquinolones no longer recommended for treatment of gonococcal infections
    • Centers for Disease Control and Prevention
    • Centers for Disease Control and Prevention. 2007. Update to CDC's sexually transmitted diseases treatment guidelines, 2006: fluoroquinolones no longer recommended for treatment of gonococcal infections. MMWR Morb Mortal Wkly Rep 56:332-336.
    • (2007) MMWR Morb Mortal Wkly Rep , vol.56 , pp. 332-336
  • 5
    • 84864993313 scopus 로고    scopus 로고
    • Update to CDC's sexually transmitted diseases treatment guidelines, 2010: Oral cephalosporins no longer a recommended treatment for gonococcal infections
    • Centers for Disease Control and Prevention
    • Centers for Disease Control and Prevention. 2012. Update to CDC's sexually transmitted diseases treatment guidelines, 2010: oral cephalosporins no longer a recommended treatment for gonococcal infections. MMWR Morb Mortal Wkly Rep 61:590-594.
    • (2012) MMWR Morb Mortal Wkly Rep , vol.61 , pp. 590-594
  • 6
    • 84898670715 scopus 로고    scopus 로고
    • Azithromycin resistance is coevolving with reduced susceptibility to cephalosporins in Neisseria gonorrhoeae in Ontario, Canada
    • Allen VG, Seah C, Martin I, Melano RG. 2014. Azithromycin resistance is coevolving with reduced susceptibility to cephalosporins in Neisseria gonorrhoeae in Ontario, Canada. Antimicrob Agents Chemother 58:2528-2534. https://doi.org/10.1128/AAC.02608-13.
    • (2014) Antimicrob Agents Chemother , vol.58 , pp. 2528-2534
    • Allen, V.G.1    Seah, C.2    Martin, I.3    Melano, R.G.4
  • 8
    • 84960427471 scopus 로고    scopus 로고
    • In vitro activity of gepotidacin, a novel triazaacenaphthylene bacterial topoisomerase inhibitor, against a broad spectrum of bacterial pathogens
    • Biedenbach DJ, Bouchillon SK, Hackel M, Miller LA, Scangarella-Oman NE, Jakielaszek C, Sahm DF. 2016. In vitro activity of gepotidacin, a novel triazaacenaphthylene bacterial topoisomerase inhibitor, against a broad spectrum of bacterial pathogens. Antimicrob Agents Chemother 60:1918-1923. https://doi.org/10.1128/AAC.02820-15.
    • (2016) Antimicrob Agents Chemother , vol.60 , pp. 1918-1923
    • Biedenbach, D.J.1    Bouchillon, S.K.2    Hackel, M.3    Miller, L.A.4    Scangarella-Oman, N.E.5    Jakielaszek, C.6    Sahm, D.F.7
  • 10
    • 84977137214 scopus 로고    scopus 로고
    • Multicenter investigation of gepotidacin (GSK2140944) agar dilution quality control determinations for Neisseria gonorrhoeae ATCC 49226
    • Jones RN, Fedler KA, Scangarella-Oman NE, Ross JE, Flamm RK. 2016. Multicenter investigation of gepotidacin (GSK2140944) agar dilution quality control determinations for Neisseria gonorrhoeae ATCC 49226. Antimicrob Agents Chemother 60:4404-4406. https://doi.org/10.1128/AAC.00527-16.
    • (2016) Antimicrob Agents Chemother , vol.60 , pp. 4404-4406
    • Jones, R.N.1    Fedler, K.A.2    Scangarella-Oman, N.E.3    Ross, J.E.4    Flamm, R.K.5
  • 12
    • 50949110901 scopus 로고    scopus 로고
    • Mechanism of action of the antibiotic NXL101, a novel nonfluoroquinolone inhibitor of bacterial type II topoisomerases
    • Black MT, Stachyra T, Platel D, Girard AM, Claudon M, Bruneau JM, Miossec C. 2008. Mechanism of action of the antibiotic NXL101, a novel nonfluoroquinolone inhibitor of bacterial type II topoisomerases. Antimicrob Agents Chemother 52:3339-3349. https://doi.org/10.1128/AAC.00496-08.
    • (2008) Antimicrob Agents Chemother , vol.52 , pp. 3339-3349
    • Black, M.T.1    Stachyra, T.2    Platel, D.3    Girard, A.M.4    Claudon, M.5    Bruneau, J.M.6    Miossec, C.7
  • 13
    • 84940938500 scopus 로고    scopus 로고
    • Insights into the mechanism of inhibition of novel bacterial topoisomerase inhibitors from characterization of resistant mutants of Staphylococcus aureus
    • Lahiri SD, Kutschke A, McCormack K, Alm RA. 2015. Insights into the mechanism of inhibition of novel bacterial topoisomerase inhibitors from characterization of resistant mutants of Staphylococcus aureus. Antimicrob Agents Chemother 59:5278-5287. https://doi.org/10.1128/AAC.00571-15.
    • (2015) Antimicrob Agents Chemother , vol.59 , pp. 5278-5287
    • Lahiri, S.D.1    Kutschke, A.2    McCormack, K.3    Alm, R.A.4
  • 14
    • 84920173087 scopus 로고    scopus 로고
    • Target-based resistance in Pseudomonas aeruginosa and Escherichia coli to NBTI 5463, a novel bacterial type II topoisomerase inhibitor
    • Nayar AS, Dougherty TJ, Reck F, Thresher J, Gao N, Shapiro AB, Ehmann DE. 2015. Target-based resistance in Pseudomonas aeruginosa and Escherichia coli to NBTI 5463, a novel bacterial type II topoisomerase inhibitor. Antimicrob Agents Chemother 59:331-337. https://doi.org/10.1128/AAC.04077-14.
    • (2015) Antimicrob Agents Chemother , vol.59 , pp. 331-337
    • Nayar, A.S.1    Dougherty, T.J.2    Reck, F.3    Thresher, J.4    Gao, N.5    Shapiro, A.B.6    Ehmann, D.E.7
  • 16
    • 0034752425 scopus 로고    scopus 로고
    • Frequency of selection of fluoroquinolone-resistant mutants of Neisseria gonorrhoeae exposed to gemifloxacin and four other quinolones
    • Ruiz J, Jurado A, Garcia-Mendez E, Marco F, Aguilar L, Jimenez de Anta MT, Vila J. 2001. Frequency of selection of fluoroquinolone-resistant mutants of Neisseria gonorrhoeae exposed to gemifloxacin and four other quinolones. J Antimicrob Chemother 48:545-548. https://doi.org/10.1093/jac/48.4.545.
    • (2001) J Antimicrob Chemother , vol.48 , pp. 545-548
    • Ruiz, J.1    Jurado, A.2    Garcia-Mendez, E.3    Marco, F.4    Aguilar, L.5    Jimenez De Anta, M.T.6    Vila, J.7
  • 17
    • 84902491074 scopus 로고    scopus 로고
    • High in vitro activity of a novel dual bacterial topoisomerase inhibitor of the ATPase activities of GyrB and ParE (VT12-008911) against Neisseria gonorrhoeae isolates with various high-level antimicrobial resistance and multidrug resistance
    • Jeverica S, Golparian D, Hanzelka B, Fowlie AJ, Maticic M, Unemo M. 2014. High in vitro activity of a novel dual bacterial topoisomerase inhibitor of the ATPase activities of GyrB and ParE (VT12-008911) against Neisseria gonorrhoeae isolates with various high-level antimicrobial resistance and multidrug resistance. J Antimicrob Chemother 69:1866-1872. https://doi.org/10.1093/jac/dku073.
    • (2014) J Antimicrob Chemother , vol.69 , pp. 1866-1872
    • Jeverica, S.1    Golparian, D.2    Hanzelka, B.3    Fowlie, A.J.4    Maticic, M.5    Unemo, M.6
  • 18
    • 24744441027 scopus 로고    scopus 로고
    • Cultivation of Neisseria gonorrhoeae in liquid media and determination of its in vitro susceptibilities to quinolones
    • Takei M, Yamaguchi Y, Fukuda H, Yasuda M, Deguchi T. 2005. Cultivation of Neisseria gonorrhoeae in liquid media and determination of its in vitro susceptibilities to quinolones. J Clin Microbiol 43:4321-4327. https://doi.org/10.1128/JCM.43.9.4321-4327.2005.
    • (2005) J Clin Microbiol , vol.43 , pp. 4321-4327
    • Takei, M.1    Yamaguchi, Y.2    Fukuda, H.3    Yasuda, M.4    Deguchi, T.5
  • 20
    • 0001986819 scopus 로고    scopus 로고
    • Antimicrobial susceptibility testing
    • 4th ed. ASM Press, Washington, DC
    • Leber AL (ed). 2016. Antimicrobial susceptibility testing, p. 5.16.1-5.16.21. Clinical microbiology procedures handbook, 4th ed. ASM Press, Washington, DC.
    • (2016) Clinical Microbiology Procedures Handbook , pp. 5.16.1-5.16.21
    • Leber, A.L.1
  • 21
    • 0001986819 scopus 로고    scopus 로고
    • Antimicrobial susceptibility testing
    • 4th ed. ASM Press, Washington, DC
    • Leber AL (ed). 2016. Antimicrobial susceptibility testing, p. 5.14.2.1-5.14.2.12. Clinical microbiology procedures handbook, 4th ed. ASM Press, Washington, DC.
    • (2016) Clinical Microbiology Procedures Handbook , pp. 5.14.2.1-5.14.2.12
    • Leber, A.L.1
  • 22
    • 0027236995 scopus 로고
    • Studies on the postantibiotic effect and the postantibiotic sub-MIC effect of meropenem
    • Odenholt-Tornqvist I. 1993. Studies on the postantibiotic effect and the postantibiotic sub-MIC effect of meropenem. J Antimicrob Chemother 31:881-892. https://doi.org/10.1093/jac/31.6.881.
    • (1993) J Antimicrob Chemother , vol.31 , pp. 881-892
    • Odenholt-Tornqvist, I.1
  • 23
    • 0026760113 scopus 로고
    • Postantibiotic sub-MIC effects of vancomycin, roxithromycin, sparfloxacin, and amikacin
    • Odenholt-Tornqvist I, Lowdin E, Cars O. 1992. Postantibiotic sub-MIC effects of vancomycin, roxithromycin, sparfloxacin, and amikacin. Antimicrob Agents Chemother 36:1852-1858. https://doi.org/10.1128/AAC.36.9.1852.
    • (1992) Antimicrob Agents Chemother , vol.36 , pp. 1852-1858
    • Odenholt-Tornqvist, I.1    Lowdin, E.2    Cars, O.3
  • 24
    • 0031960126 scopus 로고    scopus 로고
    • Postantibiotic effect and postantibiotic sub-MIC effect of levofloxacin compared to those of ofloxacin, ciprofloxacin, erythromycin, azithromycin, and clarithromycin against 20 pneumococci
    • Spangler SK, Lin G, Jacobs MR, Appelbaum PC. 1998. Postantibiotic effect and postantibiotic sub-MIC effect of levofloxacin compared to those of ofloxacin, ciprofloxacin, erythromycin, azithromycin, and clarithromycin against 20 pneumococci. Antimicrob Agents Chemother 42:1253-1255.
    • (1998) Antimicrob Agents Chemother , vol.42 , pp. 1253-1255
    • Spangler, S.K.1    Lin, G.2    Jacobs, M.R.3    Appelbaum, P.C.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.