Frequency of selection of fluoroquinolone-resistant mutants of Neisseria gonorrhoeae exposed to gemifloxacin and four other quinolones

Journal of Antimicrobial Chemotherapy

Volumn 48, Issue 4, 2001, Pages 545-548

  Ruiz, Joaquim ^a   Jurado, Angels ^a   Garcia Méndez, Elena ^b   Marco, Francesc ^a   Aguilar, Lorenzo ^b   Jimenez De Anta M T ^a   Vila, Jordi ^a  

^a HOSPITAL CLÍNIC   (Spain)

^b GLAXOSMITHKLINE   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; CIPROFLOXACIN; DNA TOPOISOMERASE (ATP HYDROLYSING) A; GEMIFLOXACIN; LEVOFLOXACIN; MOXIFLOXACIN; NALIDIXIC ACID; PROTEIN PARC; QUINOLINE DERIVED ANTIINFECTIVE AGENT; TROVAFLOXACIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL GENE; BACTERIAL MUTATION; BACTERIUM ISOLATE; BACTERIUM MUTANT; CONTROLLED STUDY; DRUG EXPOSURE; MINIMUM INHIBITORY CONCENTRATION; NEISSERIA GONORRHOEAE; NONHUMAN;

EID: 0034752425     PISSN: 03057453     EISSN: None     Source Type: Journal    
DOI: 10.1093/jac/48.4.545     Document Type: Article

References (10)

1. Fluoroquinolone resistance in Neisseria gonorrhoeae
2. Development of in-vivo resistance after quinolone treatment of gonococcal urethritis
3. Relative potential for selection of fluoroquinolone-resistant Streptococcus pneumoniae strains by levofloxacin: Comparison with ciprofloxacin, sparfloxacin and ofloxacin
4. Levofloxacin selects fluoroquinolone-resistant methicillin-resistant Staphylococcus aureus less frequently than ciprofloxacin
5. Gemifloxacin
6. Mechanisms involved in the development of resistance to fluoroquinolones in Escherichia coli isolates
7. The in-vitro activity and tentative breakpoint of gemifloxacin, a new fluoroquinolone
8. In vitro activity of gemifloxacin against clinical isolates of Neisseria gonorrhoeae with and without mutations in the gyrA gene
9. Pharmacodynamic evaluation of factors associated with the development of bacterial resistance in acutely ill patients during therapy