Salvia miltiorrhiza polysaccharide activates T Lymphocytes of cancer patients through activation of TLRs mediated -MAPK and -NF-κB signaling pathways

Journal of Ethnopharmacology

Volumn 200, Issue , 2017, Pages 165-173

  Chen, Yanan ^a   Li, Haifeng ^a   Li, Meifeng ^a   Niu, Shubin ^c   Wang, Jiaxin ^a   Shao, Hongwei ^a   Li, Ting ^b   Wang, Hui ^a,c  

^a GUANGDONG PHARMACEUTICAL UNIVERSITY   (China)

^b MACAU UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Macao)

^c BEIJING CITY UNIVERSITY   (China)

Author keywords

mitogen activated protein kinase (MAPK); nuclear factor kappa B (NF B); proliferation; Salvia miltiorrhiza polysaccharide(SMP); T lymphocyte; toll like receptor (TLR)

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 3 (4 METHYLPHENYLSULFONYL) 2 PROPENENITRILE; ACETOXYMETHYL; ALCOHOL; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; BETA ACTIN; CALCEIN; GAMMA INTERFERON; I KAPPA B KINASE ALPHA; I KAPPA B KINASE BETA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 6; METHYL GROUP; MITOGEN ACTIVATED PROTEIN KINASE; POLYSACCHARIDE; STRESS ACTIVATED PROTEIN KINASE; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 1; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 7; UNCLASSIFIED DRUG; PLANT EXTRACT;

A-549 CELL LINE; ADULT; AGED; ARTICLE; BLOOD SAMPLING; CANCER PATIENT; CELL COUNTER; CELL COUNTING; CELL PROLIFERATION; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; CYTOTOXICITY; FLOW CYTOMETRY; GENE EXPRESSION; HCT 116 CELL LINE; HEP-G2 CELL LINE; HUMAN; HUMAN CELL; IMMUNOREGULATION; IN VITRO STUDY; LYMPHOCYTE COUNT; LYMPHOCYTE PROLIFERATION; MTT ASSAY; POLYMERASE CHAIN REACTION; PRECIPITATION; PROTEIN EXPRESSION; SALVIA MILTIORRHIZA; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION; UPREGULATION; WESTERN BLOTTING; CELL CULTURE; DRUG EFFECTS; ISOLATION AND PURIFICATION; K-562 CELL LINE; METABOLISM; MIDDLE AGED; NEOPLASM; PHYSIOLOGY; PLANT ROOT; T LYMPHOCYTE;

A549 CELLS; ADULT; AGED; CELL PROLIFERATION; CELLS, CULTURED; HCT116 CELLS; HEP G2 CELLS; HUMANS; K562 CELLS; MIDDLE AGED; MITOGEN-ACTIVATED PROTEIN KINASES; NEOPLASMS; NF-KAPPA B; PLANT EXTRACTS; PLANT ROOTS; POLYSACCHARIDES; SALVIA MILTIORRHIZA; SIGNAL TRANSDUCTION; T-LYMPHOCYTES; TOLL-LIKE RECEPTORS;

EID: 85013768927     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2017.02.029     Document Type: Article

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