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Volumn 19, Issue 2, 2017, Pages

The Viral Connection to Glioblastoma

Author keywords

Cytomegalovirus; Glioblastoma; Herpesvirus; Immunotherapy; Valganciclovir

Indexed keywords

BEVACIZUMAB; CIDOFOVIR; DENDRITIC CELL VACCINE; PLACEBO; VALGANCICLOVIR; VIRUS DNA;

EID: 85013627817     PISSN: 15233847     EISSN: 15343146     Source Type: Journal    
DOI: 10.1007/s11908-017-0563-z     Document Type: Review
Times cited : (31)

References (35)
  • 1
    • 85020249099 scopus 로고    scopus 로고
    • CBTRUS statistical report: primary brain and central nervous system tumors diagnosed in the United States in 2008-2012
    • PID: 26511214
    • Ostrom QT, Gittleman H, Fulop J, Liu M, Blanda R, Kromer C, et al. CBTRUS statistical report: primary brain and central nervous system tumors diagnosed in the United States in 2008-2012. Neuro-Oncology. 2015;17 Suppl 4:iv1–62.
    • (2015) Neuro-Oncology , vol.17 , pp. iv1-iv62
    • Ostrom, Q.T.1    Gittleman, H.2    Fulop, J.3    Liu, M.4    Blanda, R.5    Kromer, C.6
  • 2
    • 84902489371 scopus 로고    scopus 로고
    • The epidemiology of glioma in adults: a “state of the science” review
    • COI: 1:CAS:528:DC%2BC2cXhtVaksrbN, PID: 24842956
    • Ostrom QT, Bauchet L, Davis FG, Deltour I, Fisher JL, Langer CE, et al. The epidemiology of glioma in adults: a “state of the science” review. Neuro-Oncology. 2014;16:896–913.
    • (2014) Neuro-Oncology , vol.16 , pp. 896-913
    • Ostrom, Q.T.1    Bauchet, L.2    Davis, F.G.3    Deltour, I.4    Fisher, J.L.5    Langer, C.E.6
  • 3
    • 0014433862 scopus 로고
    • Neoplastic transformation of hamster astrocytes in vitro by simian virus 40 and polyoma virus
    • COI: 1:STN:280:DyaF1M3lt1ymtg%3D%3D, PID: 4307975
    • Shein HM. Neoplastic transformation of hamster astrocytes in vitro by simian virus 40 and polyoma virus. Science. 1968;159:1476–7.
    • (1968) Science , vol.159 , pp. 1476-1477
    • Shein, H.M.1
  • 4
    • 0013855396 scopus 로고
    • Oncogenic activity of Mill Hill (Harris) strain of Rous sarcoma virus for hamsters
    • COI: 1:STN:280:DyaF28%2FjsFGhsA%3D%3D, PID: 4284590
    • Rabotti GF, Anderson WR, Sellers RL. Oncogenic activity of Mill Hill (Harris) strain of Rous sarcoma virus for hamsters. Nature. 1965;206:946–7.
    • (1965) Nature , vol.206 , pp. 946-947
    • Rabotti, G.F.1    Anderson, W.R.2    Sellers, R.L.3
  • 5
    • 0014524859 scopus 로고
    • Induction of brain tumors in newborn hamsters by simian adenovirus SA7
    • COI: 1:STN:280:DyaF1M3kt1eitA%3D%3D, PID: 4307781
    • Rapp F, Pauluzzi S, Waltz TA, Burdine JA, Matsen FA, Levy B. Induction of brain tumors in newborn hamsters by simian adenovirus SA7. Cancer Res. 1969;29:1173–8.
    • (1969) Cancer Res , vol.29 , pp. 1173-1178
    • Rapp, F.1    Pauluzzi, S.2    Waltz, T.A.3    Burdine, J.A.4    Matsen, F.A.5    Levy, B.6
  • 6
    • 0017279024 scopus 로고
    • Glioblastoma”. Induction of a reproducible autochonous tumor in rats with murine sarcoma virus
    • COI: 1:STN:280:DyaE287gtFWhsg%3D%3D, PID: 174026
    • Yung WK, Blank NK, Vick NA. “Glioblastoma”. Induction of a reproducible autochonous tumor in rats with murine sarcoma virus. Neurology. 1976;26:76–83.
    • (1976) Neurology , vol.26 , pp. 76-83
    • Yung, W.K.1    Blank, N.K.2    Vick, N.A.3
  • 7
    • 0037096733 scopus 로고    scopus 로고
    • Human cytomegalovirus infection and expression in human malignant glioma
    • COI: 1:CAS:528:DC%2BD38XkslWqsL4%3D, PID: 12067971, This study first detected human cytomegalovirus DNA, RNA and proteins in human glioblastoma post-surgical samples
    • Cobbs CS, Harkins L, Samanta M, Gillespie GY, Bharara S, King PH, et al. Human cytomegalovirus infection and expression in human malignant glioma. Cancer Res. 2002;62:3347–50. This study first detected human cytomegalovirus DNA, RNA and proteins in human glioblastoma post-surgical samples.
    • (2002) Cancer Res , vol.62 , pp. 3347-3350
    • Cobbs, C.S.1    Harkins, L.2    Samanta, M.3    Gillespie, G.Y.4    Bharara, S.5    King, P.H.6
  • 8
    • 39149136486 scopus 로고    scopus 로고
    • Sensitive detection of human cytomegalovirus in tumors and peripheral blood of patients diagnosed with glioblastoma
    • PID: 17951512
    • Mitchell DA, Xie W, Schmittling R, Learn C, Friedman A, McLendon RE, et al. Sensitive detection of human cytomegalovirus in tumors and peripheral blood of patients diagnosed with glioblastoma. Neuro-Oncology. 2008;10:10–8.
    • (2008) Neuro-Oncology , vol.10 , pp. 10-18
    • Mitchell, D.A.1    Xie, W.2    Schmittling, R.3    Learn, C.4    Friedman, A.5    McLendon, R.E.6
  • 9
    • 79959834313 scopus 로고    scopus 로고
    • The detection of CMV pp 65 and IE1 in glioblastoma multiforme
    • COI: 1:CAS:528:DC%2BC3MXmtl2nsL0%3D, PID: 20820869
    • Lucas KG, Bao L, Bruggeman R, Dunham K, Specht C. The detection of CMV pp 65 and IE1 in glioblastoma multiforme. J Neurooncol. 2011;103:231–8.
    • (2011) J Neurooncol , vol.103 , pp. 231-238
    • Lucas, K.G.1    Bao, L.2    Bruggeman, R.3    Dunham, K.4    Specht, C.5
  • 10
    • 20344383748 scopus 로고    scopus 로고
    • Lack of association of cytomegalovirus with human brain tumors
    • COI: 1:CAS:528:DC%2BD2MXktlWitLw%3D, PID: 15578071
    • Lau SK, Chen Y-Y, Chen W-G, Diamond DJ, Mamelak AN, Zaia JA, et al. Lack of association of cytomegalovirus with human brain tumors. Mod Pathol. 2005;18:838–43.
    • (2005) Mod Pathol , vol.18 , pp. 838-843
    • Lau, S.K.1    Chen, Y.-Y.2    Chen, W.-G.3    Diamond, D.J.4    Mamelak, A.N.5    Zaia, J.A.6
  • 12
    • 84920696061 scopus 로고    scopus 로고
    • Human cytomegalovirus viral load in tumor and peripheral blood samples of patients with malignant gliomas
    • PID: 25443081
    • Priel E, Wohl A, Teperberg M, Nass D, Cohen ZR. Human cytomegalovirus viral load in tumor and peripheral blood samples of patients with malignant gliomas. J Clin Neurosci. 2015;22:326–30.
    • (2015) J Clin Neurosci , vol.22 , pp. 326-330
    • Priel, E.1    Wohl, A.2    Teperberg, M.3    Nass, D.4    Cohen, Z.R.5
  • 13
    • 84979247227 scopus 로고    scopus 로고
    • Human herpesvirus multiplex ddPCR detection in brain tissue from low- and high-grade astrocytoma cases and controls
    • PID: 27462365, BioMed Central
    • Lin C-TM, Leibovitch EC, Almira-Suarez MI, Jacobson S. Human herpesvirus multiplex ddPCR detection in brain tissue from low- and high-grade astrocytoma cases and controls. Infect Agent Cancer. 2016;11:32. BioMed Central.
    • (2016) Infect Agent Cancer , vol.11 , pp. 32
    • Lin, C.-T.M.1    Leibovitch, E.C.2    Almira-Suarez, M.I.3    Jacobson, S.4
  • 14
    • 34047150060 scopus 로고    scopus 로고
    • RE: “Lack of association of herpesviruses with brain tumors
    • PID: 17454453, author reply 86–7
    • Scheurer ME, El-Zein R, Bondy ML, Harkins L, Cobbs CS. RE: “Lack of association of herpesviruses with brain tumors”. J Neurovirol. 2007;13:85. author reply 86–7.
    • (2007) J Neurovirol , vol.13 , pp. 85
    • Scheurer, M.E.1    El-Zein, R.2    Bondy, M.L.3    Harkins, L.4    Cobbs, C.S.5
  • 15
    • 0025221366 scopus 로고
    • Cytomegalovirus in the brain: in vitro infection of human brain-derived cells
    • COI: 1:STN:280:DyaK3M%2FjslWquw%3D%3D, PID: 2172400
    • Poland SD, Costello P, Dekaban GA, Rice GP. Cytomegalovirus in the brain: in vitro infection of human brain-derived cells. J Infect Dis. 1990;162:1252–62.
    • (1990) J Infect Dis , vol.162 , pp. 1252-1262
    • Poland, S.D.1    Costello, P.2    Dekaban, G.A.3    Rice, G.P.4
  • 16
    • 0023029105 scopus 로고
    • Human cytomegalovirus persistent infection in a human central nervous system cell line: production of a variant virus with different growth characteristics
    • PID: 3025342
    • Ogura T, Tanaka J, Kamiya S, Sato H, Ogura H, Hatano M. Human cytomegalovirus persistent infection in a human central nervous system cell line: production of a variant virus with different growth characteristics. J Gen Virol. 1986;67(Pt 12):2605–16.
    • (1986) J Gen Virol , vol.67 , pp. 2605-2616
    • Ogura, T.1    Tanaka, J.2    Kamiya, S.3    Sato, H.4    Ogura, H.5    Hatano, M.6
  • 17
    • 58249118272 scopus 로고    scopus 로고
    • The story of human cytomegalovirus and cancer: increasing evidence and open questions
    • COI: 1:CAS:528:DC%2BD1MXhvVOls7w%3D, PID: 19107226
    • Michaelis M, Doerr HW, Cinatl J. The story of human cytomegalovirus and cancer: increasing evidence and open questions. Neoplasia. 2009;11:1–9.
    • (2009) Neoplasia , vol.11 , pp. 1-9
    • Michaelis, M.1    Doerr, H.W.2    Cinatl, J.3
  • 18
    • 84879247198 scopus 로고    scopus 로고
    • Effects of valganciclovir as an add-on therapy in patients with cytomegalovirus-positive glioblastoma: a randomized, double-blind, hypothesis-generating study
    • COI: 1:CAS:528:DC%2BC3sXjslKnt7w%3D, PID: 23404447, This small, exploratory, double-blind, randomized control trial showed no benefit to adjuvant valganciclovir in regards to tumor progression, overall survival or progression free survival at 6 months
    • Stragliotto G, Rahbar A, Solberg NW, Lilja A, Taher C, Orrego A, et al. Effects of valganciclovir as an add-on therapy in patients with cytomegalovirus-positive glioblastoma: a randomized, double-blind, hypothesis-generating study. Int J Cancer. 2013;133:1204–13. This small, exploratory, double-blind, randomized control trial showed no benefit to adjuvant valganciclovir in regards to tumor progression, overall survival or progression free survival at 6 months.
    • (2013) Int J Cancer , vol.133 , pp. 1204-1213
    • Stragliotto, G.1    Rahbar, A.2    Solberg, N.W.3    Lilja, A.4    Taher, C.5    Orrego, A.6
  • 19
    • 84883439743 scopus 로고    scopus 로고
    • Survival in patients with glioblastoma receiving valganciclovir
    • PID: 24004141, This retrospective analysis of the VIGAS trial, as well as other, non-study patients receiving valganciclovir, suggests a survival benefit to receiving at least 6 months of adjuvant valganciclovir
    • Söderberg-Nauclér C, Rahbar A, Stragliotto G. Survival in patients with glioblastoma receiving valganciclovir. N Engl J Med. 2013;369:985–6. This retrospective analysis of the VIGAS trial, as well as other, non-study patients receiving valganciclovir, suggests a survival benefit to receiving at least 6 months of adjuvant valganciclovir.
    • (2013) N Engl J Med , vol.369 , pp. 985-986
    • Söderberg-Nauclér, C.1    Rahbar, A.2    Stragliotto, G.3
  • 20
    • 84891543033 scopus 로고    scopus 로고
    • The legend of cytomegalovirus and glioblastoma lives on
    • PID: 24311642
    • Weller M, Soffietti R, Brada M. The legend of cytomegalovirus and glioblastoma lives on. Neuro-Oncology. 2014;16:166.
    • (2014) Neuro-Oncology , vol.16 , pp. 166
    • Weller, M.1    Soffietti, R.2    Brada, M.3
  • 21
    • 84899430653 scopus 로고    scopus 로고
    • Immortal time bias in retrospective analysis: is there a survival benefit in patients with glioblastoma who received prolonged treatment of adjuvant valganciclovir?
    • COI: 1:CAS:528:DC%2BC2cXis1amsA%3D%3D, PID: 24338590
    • Liu C-J, Hu Y-W. Immortal time bias in retrospective analysis: is there a survival benefit in patients with glioblastoma who received prolonged treatment of adjuvant valganciclovir? Int J Cancer. 2014;135:250–1.
    • (2014) Int J Cancer , vol.135 , pp. 250-251
    • Liu, C.-J.1    Hu, Y.-W.2
  • 22
    • 84899450232 scopus 로고    scopus 로고
    • Use of Cox regression with treatment status as a time-dependent covariate to re-analyze survival benefit excludes immortal time bias effect in patients with glioblastoma who received prolonged adjuvant treatment with valganciclovir
    • PID: 24338548
    • Söderberg-Nauclér C, Peredo I, Rahbar A, Hansson F, Nordlund A, Stragliotto G. Use of Cox regression with treatment status as a time-dependent covariate to re-analyze survival benefit excludes immortal time bias effect in patients with glioblastoma who received prolonged adjuvant treatment with valganciclovir. Int J Cancer. 2014;135:248–9.
    • (2014) Int J Cancer , vol.135 , pp. 248-249
    • Söderberg-Nauclér, C.1    Peredo, I.2    Rahbar, A.3    Hansson, F.4    Nordlund, A.5    Stragliotto, G.6
  • 23
    • 85013640009 scopus 로고    scopus 로고
    • Valganciclovir and bevacizumab for recurrent glioblastoma: a single-institution experience
    • PID: 26893852
    • Peng C, Wang J, Tanksley JP, Mobley BC, Ayers GD, Moots PL, et al. Valganciclovir and bevacizumab for recurrent glioblastoma: a single-institution experience. Mol Clin Oncol. 2016;4:154–8.
    • (2016) Mol Clin Oncol , vol.4 , pp. 154-158
    • Peng, C.1    Wang, J.2    Tanksley, J.P.3    Mobley, B.C.4    Ayers, G.D.5    Moots, P.L.6
  • 24
    • 80053390591 scopus 로고    scopus 로고
    • Detection of human cytomegalovirus in medulloblastomas reveals a potential therapeutic target
    • COI: 1:CAS:528:DC%2BC3MXht12ht7bN, PID: 21946257
    • Baryawno N, Rahbar A, Wolmer-Solberg N, Taher C, Odeberg J, Darabi A, et al. Detection of human cytomegalovirus in medulloblastomas reveals a potential therapeutic target. J Clin Invest. 2011;121:4043–55.
    • (2011) J Clin Invest , vol.121 , pp. 4043-4055
    • Baryawno, N.1    Rahbar, A.2    Wolmer-Solberg, N.3    Taher, C.4    Odeberg, J.5    Darabi, A.6
  • 25
    • 84889850876 scopus 로고    scopus 로고
    • Valganciclovir in patients with glioblastoma
    • COI: 1:CAS:528:DC%2BC3sXhvVCjtbzL, PID: 24256397
    • Hellstrand K, Martner A, Bergström T. Valganciclovir in patients with glioblastoma. N Engl J Med. 2013;369:2066.
    • (2013) N Engl J Med , vol.369 , pp. 2066
    • Hellstrand, K.1    Martner, A.2    Bergström, T.3
  • 27
    • 0035879367 scopus 로고    scopus 로고
    • Prevalence of antibodies to four herpesviruses among adults with glioma and controls
    • COI: 1:STN:280:DC%2BD3MvhsFCqsQ%3D%3D, PID: 11447050
    • Wrensch M, Weinberg A, Wiencke J, Miike R, Barger G, Kelsey K. Prevalence of antibodies to four herpesviruses among adults with glioma and controls. Am J Epidemiol. 2001;154:161–5.
    • (2001) Am J Epidemiol , vol.154 , pp. 161-165
    • Wrensch, M.1    Weinberg, A.2    Wiencke, J.3    Miike, R.4    Barger, G.5    Kelsey, K.6
  • 28
    • 84944448592 scopus 로고    scopus 로고
    • Discordant humoral and cellular immune responses to Cytomegalovirus (CMV) in glioblastoma patients whose tumors are positive for CMV
    • PID: 25949880
    • Rahbar A, Peredo I, Solberg NW, Taher C, Dzabic M, Xu X, et al. Discordant humoral and cellular immune responses to Cytomegalovirus (CMV) in glioblastoma patients whose tumors are positive for CMV. OncoImmunology. 2015;4:e982391.
    • (2015) OncoImmunology , vol.4
    • Rahbar, A.1    Peredo, I.2    Solberg, N.W.3    Taher, C.4    Dzabic, M.5    Xu, X.6
  • 30
    • 84956610707 scopus 로고    scopus 로고
    • Antitumor action of temozolomide, ritonavir and aprepitant against human glioma cells
    • COI: 1:CAS:528:DC%2BC2MXhvFGktr%2FK, PID: 26603162, Springer US
    • Kast RE, Ramiro S, Lladó S, Toro S, Coveñas R, Muñoz M. Antitumor action of temozolomide, ritonavir and aprepitant against human glioma cells. J Neurooncol. 2016;126:425–31. Springer US.
    • (2016) J Neurooncol , vol.126 , pp. 425-431
    • Kast, R.E.1    Ramiro, S.2    Lladó, S.3    Toro, S.4    Coveñas, R.5    Muñoz, M.6
  • 31
    • 48249102647 scopus 로고    scopus 로고
    • Cytomegalovirus immunity after vaccination with autologous glioblastoma lysate
    • COI: 1:CAS:528:DC%2BD1cXpt1SgsLs%3D, PID: 18669440
    • Prins RM, Cloughesy TF, Liau LM. Cytomegalovirus immunity after vaccination with autologous glioblastoma lysate. N Engl J Med. 2008;359:539–41.
    • (2008) N Engl J Med , vol.359 , pp. 539-541
    • Prins, R.M.1    Cloughesy, T.F.2    Liau, L.M.3
  • 32
    • 84925045090 scopus 로고    scopus 로고
    • Tetanus toxoid and CCL3 improve dendritic cell vaccines in mice and glioblastoma patients
    • COI: 1:CAS:528:DC%2BC2MXks1yqsLc%3D, PID: 25762141, This small, double-blinded, randomized-control trial of vaccination with pp65-exposed dendritic cells (a HCMV antigen) after tetanus/diphteria toxin preconditioning showed increased progression-free survival and overall survival in glioblastoma patients
    • Mitchell DA, Batich KA, Gunn MD, Huang M-N, Sanchez-Perez L, Nair SK, et al. Tetanus toxoid and CCL3 improve dendritic cell vaccines in mice and glioblastoma patients. Nature. 2015;519:366–9. This small, double-blinded, randomized-control trial of vaccination with pp65-exposed dendritic cells (a HCMV antigen) after tetanus/diphteria toxin preconditioning showed increased progression-free survival and overall survival in glioblastoma patients.
    • (2015) Nature , vol.519 , pp. 366-369
    • Mitchell, D.A.1    Batich, K.A.2    Gunn, M.D.3    Huang, M.-N.4    Sanchez-Perez, L.5    Nair, S.K.6
  • 33
    • 84906516244 scopus 로고    scopus 로고
    • Immunological targeting of cytomegalovirus for glioblastoma therapy
    • PID: 25101224
    • Nair SK, Sampson JH, Mitchell DA. Immunological targeting of cytomegalovirus for glioblastoma therapy. OncoImmunology. 2014;3:e29289.
    • (2014) OncoImmunology , vol.3
    • Nair, S.K.1    Sampson, J.H.2    Mitchell, D.A.3
  • 34
    • 84867744197 scopus 로고    scopus 로고
    • Ex vivo functional analysis, expansion and adoptive transfer of cytomegalovirus-specific T-cells in patients with glioblastoma multiforme
    • COI: 1:CAS:528:DC%2BC38XhsFChs7fO, PID: 22508289
    • Crough T, Beagley L, Smith C, Jones L, Walker DG, Khanna R. Ex vivo functional analysis, expansion and adoptive transfer of cytomegalovirus-specific T-cells in patients with glioblastoma multiforme. Immunol Cell Biol. 2012;90:872–80.
    • (2012) Immunol Cell Biol , vol.90 , pp. 872-880
    • Crough, T.1    Beagley, L.2    Smith, C.3    Jones, L.4    Walker, D.G.5    Khanna, R.6
  • 35
    • 84903621256 scopus 로고    scopus 로고
    • Autologous T-cell therapy for cytomegalovirus as a consolidative treatment for recurrent glioblastoma
    • COI: 1:CAS:528:DC%2BC2cXhtVKlurjE, PID: 24795429
    • Schuessler A, Smith C, Beagley L, Boyle GM, Rehan S, Matthews K, et al. Autologous T-cell therapy for cytomegalovirus as a consolidative treatment for recurrent glioblastoma. Cancer Res. 2014;74:3466–76.
    • (2014) Cancer Res , vol.74 , pp. 3466-3476
    • Schuessler, A.1    Smith, C.2    Beagley, L.3    Boyle, G.M.4    Rehan, S.5    Matthews, K.6


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