Angiostatic actions of capsicodendrin through selective inhibition of VEGFR2-mediated AKT signaling and disregulated autophagy

Oncotarget

Volumn 8, Issue 8, 2017, Pages 12675-12685

  Pan, Christopher C ^a   Shah, Nirav ^a   Kumar, Sanjay ^a   Wheeler, Sarah E ^a   Cinti, Jason ^a   Hoyt, Dale G ^a   Beattie, Christine E ^a   An, Min ^a   Mythreye, Karthikeyan ^b   Rakotondraibe, L Harinantenaina ^a   Lee, Nam Y ^a,c  

^a OHIO STATE UNIVERSITY   (United States)

^b UNIVERSITY OF SOUTH CAROLINA   (United States)

^c OHIO STATE UNIVERSITY   (United States)

Author keywords

AKT; Angiogenesis; Autophagy; Endothelium; VEGF

Indexed keywords

ANGIOGENESIS INHIBITOR; AUTOPHAGY RELATED PROTEIN 5; BECLIN 1; CAPSICODENDRIN; CINNAMOSMA MACROCARPA EXTRACT; CYTOTOXIC AGENT; MICROTUBULE ASSOCIATED PROTEIN LIGHT CHAIN 3; MICROTUBULE PROTEIN; NATURAL PRODUCT; PLANT EXTRACT; PROTEIN KINASE B; UNCLASSIFIED DRUG; VASCULOTROPIN RECEPTOR 2;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIANGIOGENIC ACTIVITY; ARTICLE; AUTOPHAGY; CAPILLARY; CELL MIGRATION; CELL PROLIFERATION; CINNAMOSMA MACROCARPA; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG ISOLATION; EMBRYO; EMBRYO DEVELOPMENT; ENDOTHELIUM CELL; IN VIVO STUDY; INTERSEGMENTAL VESSEL; MEDICINAL PLANT; MOUSE; NONHUMAN; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; RECEPTOR BLOCKING; SIGNAL TRANSDUCTION; ZEBRA FISH; ANGIOGENESIS; ANIMAL; ANTAGONISTS AND INHIBITORS; C57BL MOUSE; CELL LINE; DRUG EFFECTS; FLUORESCENT ANTIBODY TECHNIQUE; HUMAN; MAGNOLIACEAE;

ANGIOGENESIS INHIBITORS; ANIMALS; AUTOPHAGY; CELL LINE; ENDOTHELIAL CELLS; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; MAGNOLIACEAE; MICE; MICE, INBRED C57BL; NEOVASCULARIZATION, PHYSIOLOGIC; PLANT EXTRACTS; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-2; ZEBRAFISH;

EID: 85013408059     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.9307     Document Type: Article

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