The reverse-mode NCX1 activity inhibitor KB-R7943 promotes prostate cancer cell death by activating the JNK pathway and blocking autophagic flux

Oncotarget

Volumn 7, Issue 27, 2016, Pages 42059-42070

  Long, Zhou ^a   Chen, Baijun ^b   Liu, Qian ^a   Zhao, Jiang ^a   Yang, Zhenxing ^a   Dong, Xingyou ^a   Xia, Liubin ^a   Huang, Shengquan ^a   Hu, Xiaoyan ^a   Song, Bo ^a   Li, Longkun ^a  

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

^b FIRST AFFILIATED HOSPITAL   (China)

Author keywords

Apoptosis; Autophagy; Cell death; NCX1; Prostate cancer

Indexed keywords

2-(2-(4-(4-NITROBENZYLOXY)PHENYL)ETHYL)ISOTHIOUREA METHANESULFONATE; CHLOROQUINE; MITOGEN ACTIVATED PROTEIN KINASE KINASE 4; SODIUM CALCIUM EXCHANGE PROTEIN; SODIUM-CALCIUM EXCHANGER 1; THIOUREA;

ANALOGS AND DERIVATIVES; ANIMAL; ANTAGONISTS AND INHIBITORS; APOPTOSIS; AUTOPHAGY; CELL CYCLE; CELL MOTION; CELL SURVIVAL; CHEMISTRY; DRUG EFFECTS; HUMAN; MALE; MAPK SIGNALING; METABOLISM; MOUSE; NUDE MOUSE; PHAGOSOME; PROSTATE TUMOR; TUMOR CELL LINE; TUMOR INVASION;

ANIMALS; APOPTOSIS; AUTOPHAGY; CELL CYCLE; CELL LINE, TUMOR; CELL MOVEMENT; CELL SURVIVAL; CHLOROQUINE; HUMANS; MALE; MAP KINASE KINASE 4; MAP KINASE SIGNALING SYSTEM; MICE; MICE, NUDE; NEOPLASM INVASIVENESS; PHAGOSOMES; PROSTATIC NEOPLASMS; SODIUM-CALCIUM EXCHANGER; THIOUREA;

EID: 85012916583     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.9806     Document Type: Article

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